KEGG   NETWORK: N01123
Entry
N01123                      Network                                

Name
Salmonella AvrA to TNF-NFKB signaling pathway
Definition
AvrA -| NFKBIA
  Expanded
K08598 -| 4792
Class
nt06123 TNF signaling (viruses and bacteria)
Type
Pathogen
Pathway
hsa05132  Salmonella infection
Disease
H00113  Salmonellosis
Gene
4792  NFKBIA; NFKB inhibitor alpha
Perturbant
K08598 (AvrA)  yopJ; YopJ protease family
Reference
  Authors
Ye Z, Petrof EO, Boone D, Claud EC, Sun J
  Title
Salmonella effector AvrA regulation of colonic epithelial cell inflammation by deubiquitination.
  Journal
Am J Pathol 171:882-92 (2007)
DOI:10.2353/ajpath.2007.070220
Reference
  Authors
Collier-Hyams LS, Zeng H, Sun J, Tomlinson AD, Bao ZQ, Chen H, Madara JL, Orth K, Neish AS
  Title
Cutting edge: Salmonella AvrA effector inhibits the key proinflammatory, anti-apoptotic NF-kappa B pathway.
  Journal
J Immunol 169:2846-50 (2002)
DOI:10.4049/jimmunol.169.6.2846
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