KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103731383Help
Entry
103731383         CDS       T03372                                 

Gene name
Ezh2
Definition
(RefSeq) enhancer of zeste 2 polycomb repressive complex 2 subunit
  KO
K11430  histone-lysine N-methyltransferase EZH2 [EC:2.1.1.43]
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00310  Lysine degradation
ngi05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    103731383 (Ezh2)
 09160 Human Diseases
  09161 Cancers
   05206 MicroRNAs in cancer
    103731383 (Ezh2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:ngi03036]
    103731383 (Ezh2)
Enzymes [BR:ngi01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     103731383 (Ezh2)
Chromosome and associated proteins [BR:ngi03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     103731383 (Ezh2)
   Polycomb group proteins
    PRC2-EZH2 complex
     103731383 (Ezh2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: SET EZH2_WD-Binding
Motif
Other DBs
NCBI-GeneID: 103731383
NCBI-ProteinID: XP_008827972
LinkDB All DBs
Position
Un
AA seq 748 aa AA seqDB search
MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEW
KQRRIQPVHIMTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNF
MVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQ
YNDDGDDDDDDGDDPDERTEKQKDLEDSQDDKESRPPRKFPSDKIFEAISSMFPDKGTAE
ELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHP
FHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRRGRL
PNNSSRPSTPTINVLEAKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPI
KMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIA
PAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVI
AQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKN
VSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVY
DKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQT
GEELFFDYRYSQADALKYVGIEREMEIP
NT seq 2247 nt NT seq  +upstreamnt  +downstreamnt
atgggccagactgggaagaaatctgagaaggggcccgtttgttggcggaagcgtgtaaaa
tcagagtacatgcggctgagacagcttaagagattcagacgagctgatgaagtaaagagt
atgtttagttccaatcgacagaaaattttggaaagaacggaaatcttaaaccaagaatgg
aagcagcgaaggatacagcctgtgcacatcatgacttctgtgagctcattgcgcgggact
agggagtgttcggtgaccagtgacttggattttccaacacaagtcatcccattaaagacc
ctgaatgcagttgcttcagtacccataatgtattcttggtctcccttacagcagaatttt
atggtggaagatgaaactgtgttgcataacattccttacatgggagatgaagttttagac
caggatggcacttttattgaagaactaataaaaaattatgatggaaaagtacatggagac
agagaatgtgggtttataaatgatgaaatttttgtggagttggtgaatgcccttggtcaa
tacaatgatgatggtgatgatgatgatgatgatggagatgatcctgatgaaagaacagaa
aaacagaaagatctagaggatagtcaagatgataaagaaagtcgaccacctcggaaattt
ccttctgataaaatttttgaagccatttcctcaatgtttccagataagggcacggcagaa
gaactaaaagaaaagtataaagagctcacagagcagcagctcccaggtgctcttcctcct
gaatgtaccccaaacatagatggaccaaatgctaaatctgttcagagggagcaaagctta
cattcatttcatacacttttctgtcggcgatgttttaagtatgactgcttcctacatccc
ttccatgcaacacccaatacatacaagcgaaaaaacacagaaacagctctggacaacaaa
ccttgtggaccacagtgttaccagcatctggagggagcaaaggaatttgccgctgccctc
actgcagagcggataaagacaccaccaaaacgcccagggggccgcagaagaggacgactt
ccaaataatagcagcagacctagcacccccaccattaatgtgctggaggcaaaggataca
gacagtgacagagaagcagggactgaaacggggggagagaacaatgataaagaagaagaa
gagaaaaaagatgagacttctagctcctcggaagcaaattctcggtgtcaaacaccaata
aagatgaagccaaatattgaacctcctgaaaatgtggaatggagtggtgctgaagcttca
atgttcagagtcctcattggtacctactacgataatttctgtgccattgctaggttaatc
gggaccaaaacatgtagacaggtgtatgagtttagagtcaaagaatccagtatcatagca
cctgcccctgctgaggatgtggacactcctccaaggaaaaagaaaagaaaacaccggttg
tgggctgcacactgcagaaagatacagctgaaaaaggatggttcctctaaccatgtttac
aactatcaaccctgtgatcatccacggcagccttgtgacagttcgtgcccttgtgtaata
gcacaaaatttttgtgagaagttttgtcaatgtagttcagagtgtcaaaaccgctttcct
ggatgccgatgcaaagcccagtgcaacaccaagcagtgcccatgctatcttgctgtccga
gagtgtgaccctgacctctgtctgacatgtggagctgctgaccattgggatagtaaaaat
gtgtcctgcaagaactgtagtattcagcgaggctccaaaaaacacttactgctggcacca
tctgatgtggcaggttggggaatttttatcaaagatcctgtacagaaaaatgaattcatc
tcagaatactgtggagagataatttctcaagatgaagcagacagacgagggaaagtgtat
gacaaatacatgtgcagctttcttttcaacttaaacaatgattttgtggtggatgcaacc
cgcaagggtaataaaattcgttttgcaaatcattcagtaaatccaaattgctatgcaaaa
gttatgatggttaatggtgatcacaggataggcatctttgccaagagagccatccagact
ggtgaagagctattttttgattacagatacagccaggctgatgccctgaagtatgtgggc
atcgaaagagaaatggaaatcccttga

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