KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103732729
Entry
103732729         CDS       T03372                                 

Gene name
Grb2
Definition
(RefSeq) growth factor receptor bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi01521  EGFR tyrosine kinase inhibitor resistance
ngi01522  Endocrine resistance
ngi04010  MAPK signaling pathway
ngi04012  ErbB signaling pathway
ngi04014  Ras signaling pathway
ngi04062  Chemokine signaling pathway
ngi04068  FoxO signaling pathway
ngi04072  Phospholipase D signaling pathway
ngi04150  mTOR signaling pathway
ngi04151  PI3K-Akt signaling pathway
ngi04380  Osteoclast differentiation
ngi04510  Focal adhesion
ngi04540  Gap junction
ngi04550  Signaling pathways regulating pluripotency of stem cells
ngi04630  JAK-STAT signaling pathway
ngi04650  Natural killer cell mediated cytotoxicity
ngi04660  T cell receptor signaling pathway
ngi04662  B cell receptor signaling pathway
ngi04664  Fc epsilon RI signaling pathway
ngi04714  Thermogenesis
ngi04722  Neurotrophin signaling pathway
ngi04910  Insulin signaling pathway
ngi04912  GnRH signaling pathway
ngi04915  Estrogen signaling pathway
ngi04917  Prolactin signaling pathway
ngi04926  Relaxin signaling pathway
ngi04935  Growth hormone synthesis, secretion and action
ngi05034  Alcoholism
ngi05160  Hepatitis C
ngi05161  Hepatitis B
ngi05163  Human cytomegalovirus infection
ngi05165  Human papillomavirus infection
ngi05200  Pathways in cancer
ngi05203  Viral carcinogenesis
ngi05205  Proteoglycans in cancer
ngi05206  MicroRNAs in cancer
ngi05210  Colorectal cancer
ngi05211  Renal cell carcinoma
ngi05213  Endometrial cancer
ngi05214  Glioma
ngi05215  Prostate cancer
ngi05220  Chronic myeloid leukemia
ngi05221  Acute myeloid leukemia
ngi05223  Non-small cell lung cancer
ngi05224  Breast cancer
ngi05225  Hepatocellular carcinoma
ngi05226  Gastric cancer
ngi05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103732729 (Grb2)
   04012 ErbB signaling pathway
    103732729 (Grb2)
   04014 Ras signaling pathway
    103732729 (Grb2)
   04630 JAK-STAT signaling pathway
    103732729 (Grb2)
   04068 FoxO signaling pathway
    103732729 (Grb2)
   04072 Phospholipase D signaling pathway
    103732729 (Grb2)
   04151 PI3K-Akt signaling pathway
    103732729 (Grb2)
   04150 mTOR signaling pathway
    103732729 (Grb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103732729 (Grb2)
   04540 Gap junction
    103732729 (Grb2)
   04550 Signaling pathways regulating pluripotency of stem cells
    103732729 (Grb2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    103732729 (Grb2)
   04660 T cell receptor signaling pathway
    103732729 (Grb2)
   04662 B cell receptor signaling pathway
    103732729 (Grb2)
   04664 Fc epsilon RI signaling pathway
    103732729 (Grb2)
   04062 Chemokine signaling pathway
    103732729 (Grb2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    103732729 (Grb2)
   04912 GnRH signaling pathway
    103732729 (Grb2)
   04915 Estrogen signaling pathway
    103732729 (Grb2)
   04917 Prolactin signaling pathway
    103732729 (Grb2)
   04926 Relaxin signaling pathway
    103732729 (Grb2)
   04935 Growth hormone synthesis, secretion and action
    103732729 (Grb2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    103732729 (Grb2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103732729 (Grb2)
  09159 Environmental adaptation
   04714 Thermogenesis
    103732729 (Grb2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103732729 (Grb2)
   05206 MicroRNAs in cancer
    103732729 (Grb2)
   05205 Proteoglycans in cancer
    103732729 (Grb2)
   05203 Viral carcinogenesis
    103732729 (Grb2)
   05231 Choline metabolism in cancer
    103732729 (Grb2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103732729 (Grb2)
   05225 Hepatocellular carcinoma
    103732729 (Grb2)
   05226 Gastric cancer
    103732729 (Grb2)
   05214 Glioma
    103732729 (Grb2)
   05221 Acute myeloid leukemia
    103732729 (Grb2)
   05220 Chronic myeloid leukemia
    103732729 (Grb2)
   05211 Renal cell carcinoma
    103732729 (Grb2)
   05215 Prostate cancer
    103732729 (Grb2)
   05213 Endometrial cancer
    103732729 (Grb2)
   05224 Breast cancer
    103732729 (Grb2)
   05223 Non-small cell lung cancer
    103732729 (Grb2)
  09165 Substance dependence
   05034 Alcoholism
    103732729 (Grb2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    103732729 (Grb2)
   05160 Hepatitis C
    103732729 (Grb2)
   05163 Human cytomegalovirus infection
    103732729 (Grb2)
   05165 Human papillomavirus infection
    103732729 (Grb2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103732729 (Grb2)
   01522 Endocrine resistance
    103732729 (Grb2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ngi04131]
    103732729 (Grb2)
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:ngi04990]
    103732729 (Grb2)
Membrane trafficking [BR:ngi04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    103732729 (Grb2)
Domain-containing proteins not elsewhere classified [BR:ngi04990]
 Src homology (SH) domain-containing proteins
  Signal transducing adaptor proteins
   103732729 (Grb2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH2_2 SH3_3 DUF5093 hSH3 SH3_4
Other DBs
NCBI-GeneID: 103732729
NCBI-ProteinID: XP_008829635
LinkDB
Position
Un
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagctactgctgacgatgagctgagcttcaaa
aggggggacatccttaaggttttgaatgaagaatgtgatcagaactggtacaaggcagaa
ctcaatgggaaggatggctttattcccaagaactacatagaaatgaagccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcatgat
ggggccttcctaatccgagagagtgagagtgctcctggggatttctccctctccgtcaag
tttggaaatgatgtgcagcacttcaaggtgctccgagatggagctgggaagtatttcctc
tgggtggtgaagttcaattctttgaatgagctggtagattaccacagatcaacatccgtg
tcaaggaaccagcagatatttctacgggacatagaacaggtgccacagcagccaacatac
gtccaggccctctttgactttgacccccaggaggatggtgagctgggcttccgccgggga
gacttcatccacgtcatggataactcagaccccaattggtggaagggggcttgccacggg
cagaccggcatgtttccccgcaattatgtcacccctgtgaaccggaacgtctaa

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