KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103742642
Entry
103742642         CDS       T03372                                 

Gene name
Egf
Definition
(RefSeq) epidermal growth factor
  KO
K04357  epidermal growth factor
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi01521  EGFR tyrosine kinase inhibitor resistance
ngi04010  MAPK signaling pathway
ngi04012  ErbB signaling pathway
ngi04014  Ras signaling pathway
ngi04015  Rap1 signaling pathway
ngi04020  Calcium signaling pathway
ngi04066  HIF-1 signaling pathway
ngi04068  FoxO signaling pathway
ngi04072  Phospholipase D signaling pathway
ngi04151  PI3K-Akt signaling pathway
ngi04510  Focal adhesion
ngi04540  Gap junction
ngi04630  JAK-STAT signaling pathway
ngi04810  Regulation of actin cytoskeleton
ngi05160  Hepatitis C
ngi05165  Human papillomavirus infection
ngi05200  Pathways in cancer
ngi05210  Colorectal cancer
ngi05212  Pancreatic cancer
ngi05213  Endometrial cancer
ngi05214  Glioma
ngi05215  Prostate cancer
ngi05218  Melanoma
ngi05219  Bladder cancer
ngi05223  Non-small cell lung cancer
ngi05224  Breast cancer
ngi05226  Gastric cancer
ngi05231  Choline metabolism in cancer
ngi05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103742642 (Egf)
   04012 ErbB signaling pathway
    103742642 (Egf)
   04014 Ras signaling pathway
    103742642 (Egf)
   04015 Rap1 signaling pathway
    103742642 (Egf)
   04630 JAK-STAT signaling pathway
    103742642 (Egf)
   04066 HIF-1 signaling pathway
    103742642 (Egf)
   04068 FoxO signaling pathway
    103742642 (Egf)
   04020 Calcium signaling pathway
    103742642 (Egf)
   04072 Phospholipase D signaling pathway
    103742642 (Egf)
   04151 PI3K-Akt signaling pathway
    103742642 (Egf)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103742642 (Egf)
   04540 Gap junction
    103742642 (Egf)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103742642 (Egf)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103742642 (Egf)
   05231 Choline metabolism in cancer
    103742642 (Egf)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103742642 (Egf)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103742642 (Egf)
   05212 Pancreatic cancer
    103742642 (Egf)
   05226 Gastric cancer
    103742642 (Egf)
   05214 Glioma
    103742642 (Egf)
   05218 Melanoma
    103742642 (Egf)
   05219 Bladder cancer
    103742642 (Egf)
   05215 Prostate cancer
    103742642 (Egf)
   05213 Endometrial cancer
    103742642 (Egf)
   05224 Breast cancer
    103742642 (Egf)
   05223 Non-small cell lung cancer
    103742642 (Egf)
  09172 Infectious disease: viral
   05160 Hepatitis C
    103742642 (Egf)
   05165 Human papillomavirus infection
    103742642 (Egf)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103742642 (Egf)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:ngi04052]
    103742642 (Egf)
Cytokines and growth factors [BR:ngi04052]
 Growth factors
  Growth factors (RTK binding)
   103742642 (Egf)
SSDB
Motif
Pfam: Ldl_recept_b EGF_CA EGF_3 cEGF EGF FXa_inhibition MTABC_N hEGF Tr-sialidase_C
Other DBs
NCBI-GeneID: 103742642
NCBI-ProteinID: XP_017656270
LinkDB
Position
Un
AA seq 774 aa
MQKLNRKLQSAGRVTSASNLKRVLNAVIFEIRLTGPQPFLLFANSQDIRHMHFDGTDYGT
LLSQQMGMVFALDYDPVESKIYFSHTALKLIERANMDGSQRERLIQGVDRPEGLAVDWIG
RRVYWTNSGKSLIEGSYLSGKNRQIIIKENVFQPRGIAVHPKAKRLFWTDTGRNPRIESS
SLQGSGRLVIVSSDLLEPSGITIDYLTDTLYWCDTKQSVIEMADLDGSKRRRLAQNDVGQ
PFAVAVFEDHLWFSDLTISSVIRVNKRTGENRVRLRGGMLKPSSLLVVHPLAKPGADPCL
HENGGCEHVCQGSFGAAQCSCHEGFMTAQDGKTCLSLEGHQTLAGNNTDLSNVVTPLDNL
TKGGASEDDNTECQRGLVSEIMVSGMNQFYQDDCAPGGCGRHAQCVSEGENATCQCLEGF
AGDGKLCSDIDECALGNMNCPAVSSQCINTEGGYVCRCSDGYEGDGIHCLDIDECQQGTH
ICGENANCTNTEGGYNCTCAGHPSAPGLTCPDSTLPSPLGEDGRHLVRNSYPGCPPSHDG
YCLHGGVCMYVEALDSYACNCVVGYIGERCQHRDLRWWGLRHAGQGQECNVTVVAVCVVV
LALLLLLGLWGAHYCRTQKQLLKNPKNPYEESSRDRSANRRAGTGAATSSCPQPWFVVLE
EHQDLKNGSLPMAGRNGQAVDAGLPSSLEPGPVHLTSWRQKPHIYGTGTKQGCXNPPSSD
KRPGFQVREGNVHLPLYREWPLAVGVEKLHPLQSADXSXQQRASDLPHXTEPIQ
NT seq 2325 nt   +upstreamnt  +downstreamnt
atgcagaaattaaacaggaagctgcagtcagcaggaagagtcacaagtgcctccaatctg
aagcgtgttttaaatgcagtcatatttgaaattcggttaacaggaccacagccattttta
ctgtttgctaattctcaagacatccgacacatgcactttgatggaaccgattatggaact
ctgctcagccagcagatgggaatggtttttgctctggattatgaccccgtggaaagcaag
atatacttttcacatacagccttgaaattgatagagagagctaatatggatggttcccag
cgggaaaggcttatccagggtgtagacaggccagaaggtcttgctgtggactggattggc
cgaagagtctactggacaaacagtgggaaatctctcatagaaggcagttatttaagcgga
aagaaccgtcaaataatcatcaaggagaatgtctttcagccacgaggaattgctgttcat
ccaaaggccaagagattattctggacagatacagggagaaatcctcgaattgaaagctct
tcccttcaaggctctggtcggctggtgatagtaagctctgatctgttggagcctagtgga
atcactattgactacttaacagacactttgtattggtgtgataccaagcagtctgtgatc
gaaatggccgatctggatggttccaaacgccgaaggcttgcccagaatgatgtaggtcag
ccctttgcggtagctgtgtttgaggatcacctgtggttctcagatttgactatatcatcg
gtaataagggtgaacaagaggactggcgagaacagggtacgtctccgcggcggcatgctg
aagccttcatcactgcttgtggtccatccactggcaaaaccaggtgcagatccctgctta
catgagaatggaggctgcgaacacgtttgtcaagggagcttcggagctgcccagtgttca
tgtcatgaaggttttatgacagctcaggatgggaaaacgtgcctttccctggagggtcac
cagacactggccggcaataatactgatctaagtaatgtggtaacaccattggacaactta
acaaagggcggagcatcggaagatgacaacacagagtgtcagcgtgggcttgtgtctgaa
atcatggtgtcaggtatgaaccagttctatcaagatgactgtgcccctggaggatgtggc
aggcatgcccagtgtgtttcagagggagagaatgccacctgtcagtgtttggaaggattt
gctggggatggaaaactgtgttctgatatagacgagtgtgcgctgggaaacatgaactgt
cctgccgtctcatcccagtgcatcaatactgaaggtggctatgtctgccggtgctcagac
ggctatgaaggagacgggatccactgtctcgatattgacgagtgccagcaagggacgcac
atctgtggagagaatgccaactgcaccaacacggagggaggctacaactgcacctgtgct
ggccacccatctgcacctggactgacttgcccagactctaccttaccctctccccttggg
gaagatggccgccatctggtcagaaatagttacccaggatgccccccgtcacatgatggg
tactgcctccatgggggtgtgtgcatgtatgttgaagcattagacagctacgcatgcaac
tgtgtggtcggctacatcggggagcgatgtcagcaccgagacttgcgatggtggggactg
cgtcacgcgggccagggtcaggagtgcaacgtcaccgtggtggctgtctgtgtggtggtg
ctggccctgttgctcctcttgggactgtggggggctcactactgcaggactcagaaacag
ctattgaaaaacccaaagaatccttatgaagagtcgagcagagacagaagtgctaacagg
cgtgccggcactggggctgcaacgtcttcttgtccccaaccttggtttgtggtcctagaa
gaacaccaagacctcaagaatgggagtctgcctatggctggcaggaatggccaggcagtg
gatgctggcctgccttcctccctggagcctgggccagtgcatctgacttcatggagacag
aagccccacatatatggaacaggcacaaaacaaggctgtntgaatccgccatccagtgat
aaaagacctggtttccaggtcagggagggaaacgtccatctacccctctatagggaatgg
cctttggctgtgggggttgagaagctgcatcctctccagtcagctgactagtcatgacaa
caaagagcctcagatctcccacactaaacagagccaattcagtga

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