Nannospalax galili (Upper Galilee mountains blind mole rat): 103744430
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Entry
103744430 CDS
T03372
Symbol
Ndufs1
Name
(RefSeq) NADH:ubiquinone oxidoreductase core subunit S1
KO
K03934
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:
7.1.1.2
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00190
Oxidative phosphorylation
ngi01100
Metabolic pathways
ngi04714
Thermogenesis
ngi04723
Retrograde endocannabinoid signaling
ngi04932
Non-alcoholic fatty liver disease
ngi05010
Alzheimer disease
ngi05012
Parkinson disease
ngi05014
Amyotrophic lateral sclerosis
ngi05016
Huntington disease
ngi05020
Prion disease
ngi05022
Pathways of neurodegeneration - multiple diseases
ngi05208
Chemical carcinogenesis - reactive oxygen species
ngi05415
Diabetic cardiomyopathy
Module
ngi_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
103744430 (Ndufs1)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
103744430 (Ndufs1)
09159 Environmental adaptation
04714 Thermogenesis
103744430 (Ndufs1)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
103744430 (Ndufs1)
09164 Neurodegenerative disease
05010 Alzheimer disease
103744430 (Ndufs1)
05012 Parkinson disease
103744430 (Ndufs1)
05014 Amyotrophic lateral sclerosis
103744430 (Ndufs1)
05016 Huntington disease
103744430 (Ndufs1)
05020 Prion disease
103744430 (Ndufs1)
05022 Pathways of neurodegeneration - multiple diseases
103744430 (Ndufs1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
103744430 (Ndufs1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
103744430 (Ndufs1)
Enzymes [BR:
ngi01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
103744430 (Ndufs1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Molybdopterin
Fer2_4
NADH-G_4Fe-4S_3
NADH_dhqG_C
Fer2
Motif
Other DBs
NCBI-GeneID:
103744430
NCBI-ProteinID:
XP_008844399
UniProt:
A0A8C6R9J1
LinkDB
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Position
Un
AA seq
727 aa
AA seq
DB search
MLRIPVKRALIGISKSPKGYVRTTGTAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQI
PRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKTKKAREGVMEFL
LANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCT
RCIRFASEIAGVDDLGTTGRGNEMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTA
RPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQ
RLTEPMVRNEKGLLIYTSWEDALSQVAGMLQSFQGKDVAAIAGGLVDAEALVSLKDLLNK
VDSDTLCTEEIFPTEGAGTDLRSNYLLNTTIAGVEEADIVLLIGTNPRFEAPLFNARIRK
SWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIASGNHPFSQVLKEAKKPMVVLGSSA
LQRNDGAAILAAVSSIAQKIRVTSGVAGDWKVMNILHRIASQVAALDLGYKPGVDAIRKN
PPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPMADVILPGAAYTEKSATYVNTE
GRAQQTKVAVTPPGLAREDWKIIRALSEIAGITLPYDTLDQVRNRLEEVSPNLVRYDDVE
GANYFQQANELAKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQA
VEEPSIC
NT seq
2184 nt
NT seq
+upstream
nt +downstream
nt
atgttaaggatacctgttaaaagggccttaataggcatttctaagtctcctaaaggatat
gtccgaacaactggcacagcagcaagcaacttgattgaagtatttgttgatggtcagtct
gtcatggtggaaccaggaactactgtcctacaagcttgtgagaaagttggcatgcagatc
cctcgattctgttatcatgaaaggttgtctgttgctggaaattgcagaatgtgcctggtt
gaaattgagaaagctcctaaggttgtagctgcttgtgctatgccagtaatgaagggctgg
aatattctgacaaactcggaaaaaactaagaaagccagagaaggtgtgatggaattctta
ttagcaaatcaccctttggactgtcctatttgtgaccagggaggtgaatgtgatcttcag
gaccagtccatgatgtttggaagtgacaggagccgatttctagaggggaaacgtgctgta
gaagacaagaacattgggccattggtaaagaccatcatgactagatgcatacagtgtacc
cggtgcatcaggtttgcaagtgagattgctggagtagatgatttgggaacaacaggcaga
gggaatgagatgcaagttggcacatacattgaaaaaatgttcatgtctgaattgtctggg
aacatcattgacatctgccctgtaggtgccctaacctctaagccttatgcctttactgcc
cgaccctgggaaaccagaaagacagaatccattgatgtaatggatgcagttggaagtaac
attgtggttagcacaagaactggagaggtgatgaggattttgccacgaatgcatgaagat
attaacgaagaatggatctctgacaaaaccagatttgcttatgatggattaaaacgtcag
agacttactgagccaatggtcagaaatgaaaaagggcttttaatatatacctcctgggaa
gatgcactctctcaagttgctggaatgttgcagagttttcaaggcaaggatgtagcagcc
attgcaggtggcttagtggatgctgaagccctagtgtctctgaaagatttgcttaataaa
gtggactctgacactttgtgcactgaagagatcttccccaccgaaggagcaggcacagat
ttacgttccaattaccttctcaatacaacaattgctggcgtggaagaggcagatattgtc
cttctgattggtacaaatccacgttttgaggcaccactgtttaatgctagaattcgaaag
agctggcttcataatgacttaaaagtggctctcataggtagtccagtggaccttacttac
agatacgaccatcttggagactctcctaaaattctgcaggacattgcttcgggaaaccac
ccattcagccaggtcttaaaggaagctaaaaaaccaatggtggttttaggcagttcggca
ctccagagaaatgatggggcagcaattcttgcagctgtgtctagcattgcacaaaagatt
cgagtaacaagtggtgttgctggagattggaaagttatgaatatccttcataggattgca
agccaggtagctgctttggaccttggctataaacctggggtagacgcaattaggaagaac
cctcccaaagtgctgtttctcctgggagcagatggaggttgtatcacacggcaggatttg
ccaaaggattgtttcattatttatcaaggacatcatggtgatgttggtgctcccatggca
gatgttattctcccaggggctgcttacacagaaaaatctgctacttatgtcaatactgag
ggccgagctcaacagaccaaagtagcagtgacacctcctggcttggcaagagaagactgg
aaaatcataagagcgctctctgagatagcaggtattactcttccatatgatactctggat
caagtgaggaaccgtttggaagaggtctcccctaatcttgttcgatatgatgatgttgaa
ggagctaattactttcaacaagcaaatgagcttgccaagctagtgaaccagcaacttctt
gctgacccacttgttccacctcagctaactataaaagacttctatatgacagattcaatt
agcagagcctcacagacaatggccaagtgtgtcaaagctgtcacagagggtgctcaggcc
gtagaggaaccatccatatgctga
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