Nannospalax galili (Upper Galilee mountains blind mole rat): 103745559
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Entry
103745559 CDS
T03372
Gene name
Ptpn11
Definition
(RefSeq) protein tyrosine phosphatase, non-receptor type 11
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi04014
Ras signaling pathway
ngi04072
Phospholipase D signaling pathway
ngi04360
Axon guidance
ngi04625
C-type lectin receptor signaling pathway
ngi04630
JAK-STAT signaling pathway
ngi04650
Natural killer cell mediated cytotoxicity
ngi04670
Leukocyte transendothelial migration
ngi04722
Neurotrophin signaling pathway
ngi04920
Adipocytokine signaling pathway
ngi04931
Insulin resistance
ngi05168
Herpes simplex virus 1 infection
ngi05205
Proteoglycans in cancer
ngi05211
Renal cell carcinoma
ngi05220
Chronic myeloid leukemia
ngi05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
103745559 (Ptpn11)
04630 JAK-STAT signaling pathway
103745559 (Ptpn11)
04072 Phospholipase D signaling pathway
103745559 (Ptpn11)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
103745559 (Ptpn11)
04650 Natural killer cell mediated cytotoxicity
103745559 (Ptpn11)
04670 Leukocyte transendothelial migration
103745559 (Ptpn11)
09152 Endocrine system
04920 Adipocytokine signaling pathway
103745559 (Ptpn11)
09156 Nervous system
04722 Neurotrophin signaling pathway
103745559 (Ptpn11)
09158 Development and regeneration
04360 Axon guidance
103745559 (Ptpn11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
103745559 (Ptpn11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
103745559 (Ptpn11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
103745559 (Ptpn11)
05211 Renal cell carcinoma
103745559 (Ptpn11)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
103745559 (Ptpn11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
103745559 (Ptpn11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
ngi01009
]
103745559 (Ptpn11)
Enzymes [BR:
ngi01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
103745559 (Ptpn11)
Protein phosphatases and associated proteins [BR:
ngi01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
103745559 (Ptpn11)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Y_phosphatase
SH2
DSPc
Y_phosphatase3
PTPlike_phytase
Motif
Other DBs
NCBI-GeneID:
103745559
NCBI-ProteinID:
XP_008845726
LinkDB
All DBs
Position
Un
AA seq
593 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD
VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF
RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR
EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGH
EYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR
NT seq
1782 nt
NT seq
+upstream
nt +downstream
nt
atgacatcccggagatggtttcacccaaacatcactggtgtggaggcagaaaatctcctg
ttgaccagaggagtcgatggcagttttttggccaggcccagtaaaagtaaccctggagac
ttcactctgtccgttagaagaaatggagctgtcacccacatcaagattcagaacactggt
gactactacgacctgtatggcggggaaaagtttgccaccttggctgagctggtccagtat
tacatggaacaccatgggcagttgaaagagaagaatggagatgtcattgagctcaaatat
ccactgaactgtgcagatcctacctctgaaaggtggttccatggtcacctgtctggaaaa
gaagcagagaagctactaacggagaaggggaagcatggcagctttcttgtccgggagagc
cagagccaccctggcgacttcgttctctcagttcgcacaggtgacgacaaaggggagagc
aacgatggcaagtccaaagtgacccacgtcatgatccgctgtcaggagctgaaatatgat
gttggtggaggagagcggtttgactctttgacagacctggtggagcattacaagaagaat
cccatggtagaaacgctgggtacagtactgcagctcaagcagcccctcaacacaactcgt
attaatgctgctgaaattgaaagccgggttcgagagctaagcaaactagctgagaccaca
gataaagtcaaacagggcttttgggaagaatttgagacactacaacaacaggagtgcaaa
cttctctacagccgcaaagaaggtcagaggcaagaaaataaaaacaaaaacagatacaaa
aacatcctaccctttgatcataccagggttgtcctgcatgatggggatcctaatgagcca
gtttccgattacatcaacgcaaatatcatcatgcctgaatttgaaaccaagtgcaacaat
tcaaagcccaaaaagagttacattgctacacaaggctgcctgcaaaatacggtgaatgac
ttctggcggatggtgttccaggagaactcccgagtcattgttatgaccacaaaggaggtg
gaaagaggaaagagcaaatgtgtcaagtactggcctgatgagtatgcactcaaagaatat
ggagttatgcgtgttaggaacgtcaaagaaagtgctgctcatgactacaccttaagagaa
ctgaaactctccaaggtcggacaagggaatacggagagaaccgtctggcaataccacttt
cggacctggccggaccatggtgtgcccagtgaccccggaggcgtactggatttcctggag
gaggtccaccacaagcaggagagcatcatggacgcaggccctgttgtggttcactgcagt
gctggaattggccggacagggacgttcattgtgatcgatatccttattgacatcatcaga
gagaaaggtgttgactgtgacattgacgttcccaaaaccattcagatggtgaggtcccag
aggtcagggatggtccagacagaagcacagtaccgtttcatctacatggccgtccaacat
tatattgaaacgctgcagcgcagaattgaggaggagcagaaaagcaagaggaaagggcat
gaatataccaatattaagtattccctcgcggaccagacaagtggtgatcagagtcccctg
ccgccttgcaccccaacaccaccctgtgcggaaatgagggaagacagcgctagagtctat
gagaacgtgggcctgatgcagcagcagaagagcttcagatga
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