Nannospalax galili (Upper Galilee mountains blind mole rat): 103750609
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Entry
103750609 CDS
T03372
Symbol
Ulk1
Name
(RefSeq) unc-51 like autophagy activating kinase 1
KO
K21357
serine/threonine-protein kinase ULK1 [EC:
2.7.11.1
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi04137
Mitophagy - animal
ngi04140
Autophagy - animal
ngi04150
mTOR signaling pathway
ngi04152
AMPK signaling pathway
ngi04211
Longevity regulating pathway
ngi05010
Alzheimer disease
ngi05014
Amyotrophic lateral sclerosis
ngi05016
Huntington disease
ngi05017
Spinocerebellar ataxia
ngi05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
103750609 (Ulk1)
04150 mTOR signaling pathway
103750609 (Ulk1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
103750609 (Ulk1)
04137 Mitophagy - animal
103750609 (Ulk1)
09150 Organismal Systems
09149 Aging
04211 Longevity regulating pathway
103750609 (Ulk1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
103750609 (Ulk1)
05014 Amyotrophic lateral sclerosis
103750609 (Ulk1)
05016 Huntington disease
103750609 (Ulk1)
05017 Spinocerebellar ataxia
103750609 (Ulk1)
05022 Pathways of neurodegeneration - multiple diseases
103750609 (Ulk1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ngi01001
]
103750609 (Ulk1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ngi04131
]
103750609 (Ulk1)
03029 Mitochondrial biogenesis [BR:
ngi03029
]
103750609 (Ulk1)
Enzymes [BR:
ngi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
103750609 (Ulk1)
Protein kinases [BR:
ngi01001
]
Serine/threonine kinases: Other
ULK family [OT]
103750609 (Ulk1)
Membrane trafficking [BR:
ngi04131
]
Autophagy
Autophagosome formation proteins
ULK complex
103750609 (Ulk1)
Mitochondrial biogenesis [BR:
ngi03029
]
Mitochondrial quality control factors
Mitophagy factors
Parkin-independent mechanism factors
103750609 (Ulk1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ATG1-like_MIT2
ATG1-like_MIT1
Kdo
ABC1
RIO1
Pkinase_fungal
Kinase-like
Motif
Other DBs
NCBI-GeneID:
103750609
NCBI-ProteinID:
XP_008851980
UniProt:
A0A8C6W3K3
LinkDB
All DBs
Position
Un
AA seq
1051 aa
AA seq
DB search
MEPGRGGVETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLL
GKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHTMRTLSEDTVRLFLQ
QIAGAMQLLHSKGIIHRDLKPQNILLSNPGGRRANPSNIRVKIADFGFARYLQSNMMAAT
LCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLV
PVIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDANASIKKSPPVPVPSYPSSGS
GSSSSSSSASHLASPPSLGEMPQLQKTLTSPADAAGFLHGSRDSGGSSKDSCDTDDFVMV
PAQFPGDLVAEAASAKPPPDSLLCSGSSLVASAGLESHGRTPSPSPTCSSSPSPSGRAGP
FSSSRYGASVPIPVPTQVHNYQRIEQNLQSPTQHQITRSSAIRRSGSTSPLGFARASPSP
PSHADGTMLARKLSLGGGRPYTPSPQVGTIPERPSWNRVPSPQGAEMRPGRSPRPGSSVP
ENSPRTTGLGCRLHSAPNLSDLYVVRPKLPKPPTDPLGTAFSPPQASTPQPCPVLQSCRP
LRGSPKLPDFLQRSPLPPILGSPTKAGPSFDFPKAPSSQNLLTLLARQGVVMTPPRNRTL
PDLSEAGPFQGQQLGPGLRPAEDTRGPFGRSFSTSRLTDLLLKAAFGTQASDSGSTDSLQ
EKPMEIAPSAGFGGNLHPGARAGGASSPAPVVFTVGSPPSGTTPPQGTRTRMFSVGSSSS
LGSAGSCSARHLVAGACGEAPELSAPGHCCSFADPLAANLEGAVTFEAPDLPEETLMEQE
HTETLHSLRFTLAFVQQVLEIAALKGSASEAAGGPVYQLQESVVADQISQLSREWGFAEQ
LVLYLKVAELLSSGLQTAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSCQGLSLRLQR
FFLDKQRLLDGIHGVTAERLILSHAVQMVQSAALDEMFQHREGCVPRYHKALLLLEGLQH
TLTDQADIENIAKCKLCIERRLSALLSGICA
NT seq
3156 nt
NT seq
+upstream
nt +downstream
nt
atggagccgggccgcggcggcgtcgagaccgtgggcaagttcgagttctcccgcaaggac
ctgatcggtcatggcgccttcgcggtggtcttcaagggacgccaccgcgagaagcacgac
ctggaggttgccgtcaaatgtattaataagaagaacctcgccaagtcccagacactgctg
ggaaaggaaatcaaaatcctcaaggaactaaagcatgaaaacattgtggcgttgtatgac
ttccaggagatggccaattctgtctacctggtcatggagtactgtaatggtggagacctg
gctgattacctacacaccatgcgtacactgagtgaagacactgtcaggctgttcctacag
cagattgctggtgccatgcagctgctacacagcaagggcatcatccaccgagatttgaag
ccccagaacatcctgctctccaaccctgggggacgccgtgccaatcccagcaacattcgt
gtcaagattgctgactttggatttgcgaggtacctccagagcaatatgatggcggccaca
ctctgcggctctcccatgtacatggcccctgaggtcatcatgtcccagcactatgatggg
aaagctgacctttggagcatcggcaccatcgtttatcagtgtctgactgggaaggcccct
ttccaggccagcagtcctcaggacctgcgtctgttttatgagaagaacaagacactggtc
cctgtcattccacgagagacgtcggctcctctgcggcagctgctcctggctctgttgcaa
cgcaaccacaaggaccgaatggattttgatgagtttttccaccaccctttcttggatgcc
aacgcgtccatcaagaagtcccctccagtgcctgtaccttcttacccaagttcggggtct
ggtagcagctctagcagcagttctgcttcccacctggcctccccaccgtccctgggagaa
atgccacagctgcagaagacgcttacctccccagctgatgctgctggcttcctgcatggt
tcccgggactctggtggcagcagcaaagactcttgtgacacagatgactttgtcatggtc
ccagcccagtttccaggtgacctagtagctgaagcagcaagtgccaagcctccgcctgac
agcctgctgtgcagcgggagctcactggtggcctctgctggcctggagagccatggtcgc
accccatctccctctccaacctgcagcagctctcccagcccctctggccgggctggcccc
ttctccagcagcaggtatggtgcctcggtccccattcctgtccccactcaggtacacaat
taccagcgcattgagcagaacctgcagtcacccacccagcaccagataacccggtcctct
gccatccgaaggtcaggcagtaccagccccctgggctttgctcgggccagcccgtcaccc
ccttcccatgctgatggaactatgctggccaggaagttgtcactgggtggtggccgcccc
tacacaccatctccccaagtgggaaccatccctgagcgacccagctggaacagagtgccc
tccccacaaggagctgagatgcggcctggcaggtcaccacgaccaggctcctctgtgcct
gagaactccccaagaaccaccggtttgggctgccgcctacacagcgcccccaacctgtct
gacctctatgttgtgcgcccgaagctacccaagcccccaacagacccgctgggaactgcc
ttcagtccgcctcaggccagcacaccccagccatgcccagtgttgcagtcctgccggccc
cttcgtggctcacccaagctgcctgacttcctgcagcggagccccctgccccccatcctg
ggctctcccaccaaggctgggccttcattcgacttccccaaggcccccagctctcagaac
ttgctgaccctgttggcccggcagggtgtggtgatgacacctcctcggaaccgcacattg
cctgacctctcagaggcagggcccttccagggacagcagctgggacctggcctgcggcct
gccgaagataccaggggcccctttggccggtccttcagtaccagccgccttacagaccta
ctgcttaaggctgcctttggaacacaagcctcagactcaggcagcactgacagtctgcag
gaaaagcccatggagattgcaccctctgctggctttggagggaacctgcatccaggagcc
cgtgctgggggtgccagcagcccggcacctgtggtgttcaccgtgggttccccacccagt
ggaaccacaccaccccagggcacccgaaccaggatgttctcagtgggctcttccagctcc
ctgggctctgctggctcctgctctgcccgccacctggtggctggggcctgtggtgaggcc
cctgagctttctgccccaggccactgctgcagctttgctgatcctcttgctgccaacctg
gagggggctgtgacgtttgaggctcctgaccttcctgaggagactcttatggagcaagag
cacacagagaccttgcacagtctgcgcttcacactggcatttgtgcagcaagttctggag
attgcggccttgaagggtagtgccagtgaggcagctgggggccctgtgtaccagcttcag
gagagcgtggtggctgaccagattagccagctgagccgagagtggggttttgctgagcag
ctggtgctgtacttgaaggtggctgagctgctgtcctcaggcctacagaccgccattgat
cagatccgagctggcaagctttgcctgtcgtccactgtgaagcaggtggtacgcagactg
aacgagctatataaggccagtgtggtgtcctgccagggcctcagcctgcggttgcagcgc
ttcttcctggacaagcaacggctcctggatggcatccatggtgtcaccgctgagaggctt
atcctcagccatgctgtgcagatggtacagtcggctgccctagatgagatgttccagcac
cgagagggctgtgtaccacgctatcataaggccctgctgttgctagagggtctacaacac
acactcacggaccaggcagacatagagaacatagccaagtgcaagctatgcattgagcgg
agactttcggccctgctgagtggcatctgtgcctaa
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