Nomascus leucogenys (northern white-cheeked gibbon): 100589614
Help
Entry
100589614 CDS
T03265
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04010
MAPK signaling pathway
nle04020
Calcium signaling pathway
nle04022
cGMP-PKG signaling pathway
nle04024
cAMP signaling pathway
nle04260
Cardiac muscle contraction
nle04261
Adrenergic signaling in cardiomyocytes
nle04270
Vascular smooth muscle contraction
nle04723
Retrograde endocannabinoid signaling
nle04725
Cholinergic synapse
nle04726
Serotonergic synapse
nle04727
GABAergic synapse
nle04911
Insulin secretion
nle04912
GnRH signaling pathway
nle04921
Oxytocin signaling pathway
nle04924
Renin secretion
nle04925
Aldosterone synthesis and secretion
nle04927
Cortisol synthesis and secretion
nle04929
GnRH secretion
nle04934
Cushing syndrome
nle04935
Growth hormone synthesis, secretion and action
nle05010
Alzheimer disease
nle05020
Prion disease
nle05022
Pathways of neurodegeneration - multiple diseases
nle05207
Chemical carcinogenesis - receptor activation
nle05410
Hypertrophic cardiomyopathy
nle05412
Arrhythmogenic right ventricular cardiomyopathy
nle05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100589614 (CACNA1S)
04020 Calcium signaling pathway
100589614 (CACNA1S)
04024 cAMP signaling pathway
100589614 (CACNA1S)
04022 cGMP-PKG signaling pathway
100589614 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
100589614 (CACNA1S)
04929 GnRH secretion
100589614 (CACNA1S)
04912 GnRH signaling pathway
100589614 (CACNA1S)
04921 Oxytocin signaling pathway
100589614 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
100589614 (CACNA1S)
04924 Renin secretion
100589614 (CACNA1S)
04925 Aldosterone synthesis and secretion
100589614 (CACNA1S)
04927 Cortisol synthesis and secretion
100589614 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
100589614 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
100589614 (CACNA1S)
04270 Vascular smooth muscle contraction
100589614 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
100589614 (CACNA1S)
04725 Cholinergic synapse
100589614 (CACNA1S)
04726 Serotonergic synapse
100589614 (CACNA1S)
04723 Retrograde endocannabinoid signaling
100589614 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
100589614 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
100589614 (CACNA1S)
05020 Prion disease
100589614 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
100589614 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100589614 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
100589614 (CACNA1S)
05414 Dilated cardiomyopathy
100589614 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100589614 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
nle04040
]
100589614 (CACNA1S)
Ion channels [BR:
nle04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
100589614 (CACNA1S)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
CAC1F_C
Motif
Other DBs
NCBI-GeneID:
100589614
NCBI-ProteinID:
XP_030674542
Ensembl:
ENSNLEG00000018075
LinkDB
All DBs
Position
9:14873626..14947060
Genome browser
AA seq
1873 aa
AA seq
DB search
MEPSSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLENPLRKACISIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNSLNLSLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFTIVFLGVFTVILEQVNVIQSHTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFTGTDIVATVENE
EPSPCARTGSGRRCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLD
EDLRGYMSWITQGEVMDVEDFREGKLSLDEGGSDTESLYEIAGLNKIIQFIRHWRQWNRI
FRWKCHDIVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTRLQDIANRVLLSLFTVEML
VKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVRRSNFDNF
PQALISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERKRRKMSKGLPEKSEEEKSTMAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPLSPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILKHFDIGFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNMLDLLVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCMFVAISTIGNIVLVTTLLQFMFACIGVQLFKGKFFRCTDL
SKMTEEECRGYYYVYKDGDPTQIELRHREWVHSDFHFDNVLSAMMSLFTVSTFEGWPQLL
YKAIDSNEEDMGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LNKNQRQCVQYALKARPLRCYIPKNPYQYQVWYIVTSSYFEYLMFALIMLNTICLGMQHY
NQSEQMNHISDILNVAFTIIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNIDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKLCDPESDYAPGEEYTCGTNFAYYYFISFYMLCAFLVINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDVVQIQAGLR
TIEEEAAPEIRRTISGDLAAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPP
VMANQRPLQFAEIEMEEMESPVFLEDFPQDPRTNPLARANINNANANVAYGNSNHSNSQV
FSSVHYEKEFPEETETPATRGRALGQPCRALGPHSKPCVEMLKGLLTQRAMPRGQALPAP
CQCPRVESPMPEDRKSSTSGSLHEETPHSRSDGENTSRCSAPATALLIQEALVRGGLGTL
AADANFIMATGQALADACQMEPEEVEVMATELLKGREAPEGMASSLGCLNLGSSLGSLDQ
HQGSQETLIPPRL
NT seq
5622 nt
NT seq
+upstream
nt +downstream
nt
atggagccgtcctcaccccaggatgaaggcctgaggaagaaacagcccaagaagccggtt
cctgagattctgccaaggccacccagggccttgttctgcctgaccctggagaatcccctg
aggaaggcctgcatcagcatcgtagaatggaagccctttgagacaatcatcttgctcacc
atctttgccaactgtgtggccctggccgtgtacctgcccatgccggaagatgacaacaac
tctctgaacctcagcctggagaagctggagtatttcttcctcatcgtcttctcaattgaa
gccgccatgaagatcattgcctacggcttcttattccaccaggacgcttacctgcgcagt
ggctggaatgtgctggacttcaccattgtcttcctgggggtcttcaccgtgattctggaa
caggttaacgtcatccaaagccacacagccccaatgagcagcaaaggagccggcttggat
gtcaaggccctcagagccttccgagtgctcagacccctccggctggtgtcgggggtgcct
agcctgcaggtggtcctgaactccatcttcaaggccatgctccccctcttccacatcgcc
ctgctggtcctctttatggtcatcatctatgccatcatcgggctggagctcttcaagggc
aagatgcacaagacctgctacttcactggcacagatatcgtggccacggtggagaatgag
gagccatcaccctgcgccaggacgggctcagggcgccggtgcaccatcaatggcagtgag
tgccggggcggctggccagggcccaaccatggcatcacccacttcgacaacttcggcttc
tccatgctcaccgtgtaccagtgcatcaccatggagggatggactgacgtcctttactgg
gtcaatgatgccatcgggaatgagtggccctggatctattttgtcaccctcattctgctg
ggatccttcttcatcctcaacctggtgctgggtgtcctgagcggggaattcaccaaggag
cgggagaaggccaagtccaggggaaccttccagaagctccgggagaagcagcagctagat
gaggaccttcggggctacatgagctggatcacgcagggcgaggtcatggacgttgaggac
ttcagagaaggaaaactgtctttggatgaaggtggctctgacacagagagcctgtatgaa
attgcaggcttgaacaaaatcatccagttcatccggcattggaggcagtggaaccgcatc
tttcgctggaagtgccatgacatcgtgaagtccaaggtcttctattggctggtgattctc
atcgttgccctcaacaccctgtctatcgcctcagagcaccacaaccagcctctctggctg
acccgtttgcaagacattgccaaccgggtgctgctgtccctcttcaccgttgagatgctg
gtgaagatgtacgggctgggcctgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggcatcctggagatcctgctggtggagtcaggcgccatgacg
cccctgggcatctccgtgcttcgctgcatccgcctgctgaggatcttcaagatcaccaaa
tattggacatcgctgagcaacctggtggcatccctgctcaattccatccgctccatcgcc
tccctgctgctgctgctcttcctcttcatcgtcatcttcgccctcctgggcatgcagctc
tttgggggaaggtatgactttgaggacacagaagtacggcgcagcaacttcgacaacttt
ccccaagccctcatcagcgtcttccaggtcctgacaggtgaagactggacctcgatgatg
tacaatgggatcatggcctatggcgggccgtcctaccccggcatgcttgtgtgcatttac
ttcatcatccttttcgtctgtggcaactacatcctgctcaatgtcttcctggccattgcc
gtggacaacctggctgaggcagagagcctgacttctgctcagaaggccaaggccgaggag
agaaaacgcaggaagatgtccaagggtctcccagaaaagtcagaggaggagaagtccacg
atggccaagaagctggagcagaaacccaagggtgagggcatccccaccactgccaagctg
aaaatcgatgagtttgaatctaatgtcaatgaggtgaaggatccctacccctcagccgac
ttcccaggggacgacgaggaagatgagcccgagatcccgctgagcccccgaccacgtccc
ctggctgagctgcagctgaaagagaaggccgtgcccattccagaagccagctccttcttc
atcttcagccccaccaataagatccgtgtcctgtgtcaccgcatcgtcaatgccacctgg
ttcaccaacttcatcctgctcttcatcctgctcagcagtgctgcactggctgcggaagac
cccatccgggctgattccatgaggaatcagatccttaaacactttgacatcgggttcacc
tctgtcttcactgtggagattgtcctcaagatgacgacctacggagccttcctgcacaag
ggttccttctgccgcaattacttcaacatgctggacctgctggtggtggccgtgtccctc
atctccatgggacttgagtccagcgccatctccgtggtgaagatcctgagggtgctgagg
gtgcttcgaccactcagagccatcaacagagccaaggggttgaagcacgtggtgcagtgc
atgttcgtggccatcagcaccatcgggaacatcgtgctggtcactaccctcctacagttc
atgtttgcctgcatcggcgtccagctcttcaaggggaagttcttcaggtgcaccgacttg
tccaagatgacagaggaggagtgcaggggctactactacgtgtacaaggacggggacccc
acacagatagagctgcgtcaccgcgagtgggtacacagcgacttccacttcgacaatgtg
ctctcagccatgatgtccctcttcacggtctccaccttcgagggatggcctcagctgctg
tacaaggccatagactccaatgaggaggacatgggtcccatctacaacaaccgtgtggag
atggccatcttcttcatcatctacatcatcctcattgccttcttcatgatgaacatcttc
gtgggctttgtcattgtcaccttccaggagcagggagagactgagtacaagaactgtgag
ctgaacaagaaccagcgccaatgtgtacagtatgccctgaaggcccgcccactgaggtgc
tacattcccaaaaacccataccagtaccaggtgtggtacattgtcacctcctcctacttc
gaatacctgatgtttgccctcatcatgctcaacaccatctgcctcggcatgcagcactac
aaccagtcagagcagatgaaccacatctcagacatcctcaatgtggccttcactatcatc
ttcaccctggagatgatcctcaagctcatggccttcaaggccaggggctactttggggac
ccctggaacgtgtttgacttcctgattgtcattggcagcatcattgatgtcatcctcagc
gagatcgacactttcctggcctccagcgggggactgtattgcctgggtggaggctgcggg
aacattgacccagatgagagtgcccgcatctccagcgccttcttccgcctgttccgtgtc
atgaggctgatcaagctgctgagccgggcagagggagtgcgcaccctcctgtggacgttc
atcaagtccttccaggccctaccctacgtggctctgctcatcgtcatgctcttcttcatc
tacgctgtcatcggcatgcagatgtttgggaagatcgccttggtggatgggacccaaata
aaccggaacaacaacttccagaccttcccacaagctgtgctactgctcttcaggtgtgca
acaggtgaggcctggcaggagatcctactggcctgcagctatgggaagctgtgtgaccca
gaatcggactatgccccaggggaggagtacacatgtggcaccaactttgcatactactac
ttcatcagcttctacatgctctgtgccttcctggtcatcaacctctttgtggctgtcatc
atggacaattttgactacctcacccgggactggtccatcctgggccctcatcacctggat
gagttcaaggccatctgggcagagtatgacccagaggctaaggggagaatcaaacacctg
gacgtggtgaccctgctgagaaggattcagcctcctctgggctttgggaagttctgccca
catcgggtagcttgtaagcggctggtgggcatgaacatgcccctgaacagcgacggcaca
gtcaccttcaatgccacactgttcgccctggtccgcacagcactcaagatcaagacggaa
ggtaactttgagcaggccaatgaggagctgagggccatcatcaagaagatctggaagaga
accagcatgaagctcttggaccaggtcatccctccaataggagatgatgaggtgacagtg
gggaagttctacgccacattcctcatccaggagcacttccggaagttcatgaaacgccag
gaggagtattatggctatcggcccaagaaggacgttgtacagatccaggcaggactgcgg
accattgaggaagaggcagcccccgagatccgtcgcaccatctcaggagacctggctgct
gaggaggagctggagagagccatggtggaggctgcaatggaagagggaatattccggagg
actggaggcctgtttggccaggtggacaacttcctggaaaggaccaactccctgcccccc
gtcatggccaatcagagacccctccagtttgccgagatagagatggaagagatggagtca
cctgtcttcttggaggacttcccacaagatccacgcaccaaccccctggctcgtgccaat
atcaacaacgccaacgccaatgtcgcctatggcaacagcaaccatagcaacagccaggtg
ttttccagtgtccactatgaaaaggagttcccagaagagacagagacgcctgctaccaga
ggacgagcccttggccaaccctgcagggccctgggaccccacagcaaaccctgtgtggag
atgctgaagggactgctgacccagagggcaatgccaagaggccaggcacttcctgccccc
tgccagtgccccagggtggagtcccccatgcctgaggacagaaagagctccacatcaggg
tctctgcatgaggagacgccccacagcaggagcgatggggagaatacttccaggtgctca
gcaccagctacagccctgctgatccaagaggctctagttcgagggggcctgggcaccttg
gcggctgatgcaaacttcatcatggcaacaggccaggccctggcagatgcctgccaaatg
gaaccagaggaagtggaggtcatggcaacagagctactgaaaggacgagaggccccagaa
ggcatggccagctccctgggatgcctgaacctcgggtcctccctgggcagcctcgaccag
caccagggctcccaggagacccttattcctcccaggctgtga
DBGET
integrated database retrieval system
