Nomascus leucogenys (northern white-cheeked gibbon): 100597533
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Entry
100597533 CDS
T03265
Symbol
INSR
Name
(RefSeq) insulin receptor isoform X1
KO
K04527
insulin receptor [EC:
2.7.10.1
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04010
MAPK signaling pathway
nle04014
Ras signaling pathway
nle04015
Rap1 signaling pathway
nle04022
cGMP-PKG signaling pathway
nle04066
HIF-1 signaling pathway
nle04068
FoxO signaling pathway
nle04072
Phospholipase D signaling pathway
nle04150
mTOR signaling pathway
nle04151
PI3K-Akt signaling pathway
nle04152
AMPK signaling pathway
nle04211
Longevity regulating pathway
nle04213
Longevity regulating pathway - multiple species
nle04520
Adherens junction
nle04910
Insulin signaling pathway
nle04913
Ovarian steroidogenesis
nle04923
Regulation of lipolysis in adipocytes
nle04930
Type II diabetes mellitus
nle04931
Insulin resistance
nle04932
Non-alcoholic fatty liver disease
nle04960
Aldosterone-regulated sodium reabsorption
nle05010
Alzheimer disease
nle05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100597533 (INSR)
04014 Ras signaling pathway
100597533 (INSR)
04015 Rap1 signaling pathway
100597533 (INSR)
04066 HIF-1 signaling pathway
100597533 (INSR)
04068 FoxO signaling pathway
100597533 (INSR)
04072 Phospholipase D signaling pathway
100597533 (INSR)
04022 cGMP-PKG signaling pathway
100597533 (INSR)
04151 PI3K-Akt signaling pathway
100597533 (INSR)
04152 AMPK signaling pathway
100597533 (INSR)
04150 mTOR signaling pathway
100597533 (INSR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04520 Adherens junction
100597533 (INSR)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100597533 (INSR)
04923 Regulation of lipolysis in adipocytes
100597533 (INSR)
04913 Ovarian steroidogenesis
100597533 (INSR)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
100597533 (INSR)
09149 Aging
04211 Longevity regulating pathway
100597533 (INSR)
04213 Longevity regulating pathway - multiple species
100597533 (INSR)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100597533 (INSR)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100597533 (INSR)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
100597533 (INSR)
04932 Non-alcoholic fatty liver disease
100597533 (INSR)
04931 Insulin resistance
100597533 (INSR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nle01001
]
100597533 (INSR)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
nle04090
]
100597533 (INSR)
Enzymes [BR:
nle01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100597533 (INSR)
Protein kinases [BR:
nle01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
100597533 (INSR)
CD molecules [BR:
nle04090
]
Proteins
100597533 (INSR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
Insulin_TMD
fn3
Kinase-like
DUF4476
B2
Motif
Other DBs
NCBI-GeneID:
100597533
NCBI-ProteinID:
XP_030663572
Ensembl:
ENSNLEG00000000403
LinkDB
All DBs
Position
Unknown
AA seq
1382 aa
AA seq
DB search
MGTGGRRGAAAAPLLVAVAALLLGAAGHLYPGEVCPGMDIRNNLTRLHELENCSVIEGHL
QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL
VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE
ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL
GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNSRRQG
CHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC
TVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL
EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE
RNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQ
NVTEFDGQDACGSNSWTVVDIDPPLRSTDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS
DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE
RQAEDSELFELDYCLKGLKLPSRTWSPPFESEDSQKHNQSEYEDSAGECCSCPKTDSQIL
KELEESSFRKTFEDYLHNVVFVPRKTSSGTGAEDPRPSRKRRSLGDVGNVTAAVPTVAAF
PNTSSTSVPTSPEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYV
SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCV
SRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIG
PLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR
EKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKG
FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA
AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV
RWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDN
CPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENKAPESEELEME
FEDMENVPLDRSSHCQREEAGGRDGGSSLGFKRSYEEHIPYTHMNGGKKNGRILTLPRSN
PS
NT seq
4149 nt
NT seq
+upstream
nt +downstream
nt
atgggcacagggggccggcggggggcggcggcggcgccgctgctggtggcggtggccgcg
ctgctattgggcgccgcgggccacctgtaccccggagaggtgtgtcccggcatggatatc
cggaacaacctcactaggttgcatgagctggagaattgctctgtcatcgaaggacacttg
cagatactcttgatgttcaaaacgaggcccgaagatttccgagacctcagtttccccaaa
ctcataatgatcactgattacttgctgctcttccgtgtctatgggctcgagagcctgaag
gacctgttccccaacctcacggtcatccggggatcacgactgttctttaactacgcgctg
gtcatcttcgagatggttcacctcaaggaactcggcctctacaacctgatgaacatcacc
cggggttctgtccgcatcgagaagaacaatgagctctgttacttggccactatcgactgg
tcccgtatcctggattctgtggaggataattacatcgtattgaacaaagatgacaacgag
gagtgtggagacatctgtccgggtaccgcgaagggcaaaaccaactgcccagccaccgtc
atcaacgggcagtttgtcgaacggtgttggactcatagtcactgccagaaagtttgcccg
accatctgtaagtcacatggctgcactgccgaaggcctctgttgccacagcgagtgcctg
ggcaactgttctgagcccgacgaccccaccaagtgcgtggcctgccgcaacttctacctg
gacggcagatgtgtggagacctgcccgcccccgtactaccacttccaggactggcgctgt
gtgaacttcagcttctgccaggacctgcaccacaaatgcaagaactcgcggaggcagggc
tgccaccagtacgtcattcacaacaacaagtgcatccctgagtgtccctccgggtacacg
atgaattccagcaacttgctgtgcaccccatgcctgggtccctgtcccaaggtgtgccac
ctcctagaaggcgagaagaccatcgactcggtgacgtctgcccaggagctccgaggatgc
accgtcatcaacgggagtctgatcatcaacattcgaggaggcaacaatctggcagctgag
ctagaagccaacctcggcctcattgaagaaatttcaggttatctaaaaatccgccgatcc
tacgctctggtgtcactttccttcttccggaagttacgtctgattcgaggagagaccttg
gaaatcgggaactactccttctatgccttggacaaccagaacctaaggcagctctgggat
tggagcaaacacaacctcaccatcactcaggggaaactcttcttccactataaccccaaa
ctctgcctgtcagaaatccacaagatggaagaagtttcaggaaccaaggggcgccaggag
agaaatgacattgccctgaagaccaatggggaccaggcatcctgtgaaaatgagttactt
aaattttcttacattcggacatcttttgacaagatcttgctgagatgggagccgtactgg
ccccccgacttccgagacctcttggggttcatgctgttctacaaagaggccccttatcag
aatgtgacggagttcgacgggcaggatgcgtgtggttccaacagctggacggtggtagac
attgatccacccctgaggtccaccgaccccaaatcacagaaccacccaggatggctgatg
cggggtctcaagccctggacccagtatgccatctttgtgaagaccctggtcaccttttcg
gatgaacgccggacctatggggccaagagtgacatcatttatgtccagacagatgccacc
aacccctccgtgcccctggatccaatctcagtgtctaactcatcatcccagattattctg
aagtggaagcccccctcagaccccaatggcaacatcacccactacctggttttctgggag
aggcaggcggaagacagtgagctgttcgagctggattattgcctcaaagggctgaagctg
ccctcgaggacctggtctccaccattcgagtctgaagattctcagaagcacaaccagagt
gaatatgaggattcggccggcgaatgttgctcctgtccaaagacagactctcagatcctg
aaggagctggaggagtcctcgtttaggaagacgttcgaggattacctgcacaacgtggtt
ttcgtccccagaaaaacctcttcaggcactggtgccgaggaccctaggccatctcggaaa
cgcaggtcccttggcgatgttgggaatgtgacggcagccgtgcccacggtggcagctttc
cccaacacttcctcaaccagcgtgcccacgagtccggaggagcacaggccctttgagaag
gtggtgaacaaggagtcactggtcatctccggcttgcgacacttcacgggctatcgcatc
gagctgcaggcttgcaaccaagacacccctgaggaacggtgcagtgtggcagcctacgtc
agtgccaggaccatgcctgaagccaaggctgatgacattgtcggccctgtgacgcacgaa
atctttgagaacaacgtcgtccacttgatgtggcaggagccgaaggaacccaatggtctg
attgtgctgtatgaagtgagttatcggcgatatggcgatgaggagctgcatctctgcgtc
tcccgcaagcacttcgctctggaacggggctgcaggctgcgcgggctgtcgccggggaac
tacagcgtgcgagtccgggccacctccctcgcgggcaacggctcctggacagaacccacc
tatttctacgtgacagactatttagatgtcccgtcaaatattgcaaaaattatcatcggc
cccctcatctttgtctttctcttcagtgttgtgattggaagtatttatctattcctgaga
aagaggcagccagatgggccgctgggaccactttacgcttcttcaaatcccgagtatctc
agtgccagtgatgtgtttccatgctctgtgtacgtgccggacgagtgggaggtgcctcga
gagaagatcaccctccttcgagagctggggcagggctcctttggcatggtgtatgagggc
aacgccagggacatcatcaagggtgaggcagagacccgcgtggcagtgaagacggtcaac
gagtcagccagtctccgagagcggattgagttcctcaatgaggcctcggtcatgaagggc
ttcacctgccatcatgtggtgcgcctcctgggagtggtgtccaagggccagcccacgctg
gtggtgatggagctgatggctcacggagacctgaagagctacctccgttctctgcggcca
gaggctgagaataatcctggccgccctccccctaccctgcaagagatgattcagatggcg
gcagagattgctgacgggatggcctacctgaacgccaagaagtttgtgcatcgggacctg
gcagcgagaaactgcatggttgcccatgattttactgtcaaaattggagactttggaatg
accagagacatctatgaaacggattactaccggaaagggggcaagggtctactccctgta
cggtggatggcgccggagtccctgaaggatggggtctttaccacttcttctgacatgtgg
tcctttggcgtggtcctttgggaaatcaccagcttggcagaacagccttaccaaggcctg
tcgaatgaacaggtgttgaaatttgtcatggatggagggtatctggatcaacctgacaac
tgtccagagagagtcactgacctcatgcgcatgtgctggcaattcaaccccaagatgagg
ccaaccttcctggagattgtcaacctgctcaaggatgacctgcaccccagctttccggag
gtgtcgttcttccacagcgaggagaacaaggctcccgagagtgaggagctggagatggag
tttgaggacatggagaatgtgcccctggaccgttcctcgcactgtcagagggaggaggcg
gggggccgggatggagggtcctcgctaggtttcaagcggagctacgaggaacacatccct
tacacacacatgaacggaggcaagaaaaacgggcggattctgaccttgcctcggtccaat
ccttcctaa
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integrated database retrieval system
