KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100598877
Entry
100598877         CDS       T03265                                 

Gene name
STAT3
Definition
(RefSeq) signal transducer and activator of transcription 3 isoform X1
  KO
K04692  signal transducer and activator of transcription 3
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle01521  EGFR tyrosine kinase inhibitor resistance
nle04062  Chemokine signaling pathway
nle04066  HIF-1 signaling pathway
nle04068  FoxO signaling pathway
nle04217  Necroptosis
nle04550  Signaling pathways regulating pluripotency of stem cells
nle04630  JAK-STAT signaling pathway
nle04659  Th17 cell differentiation
nle04917  Prolactin signaling pathway
nle04920  Adipocytokine signaling pathway
nle04931  Insulin resistance
nle04933  AGE-RAGE signaling pathway in diabetic complications
nle04935  Growth hormone synthesis, secretion and action
nle05145  Toxoplasmosis
nle05160  Hepatitis C
nle05161  Hepatitis B
nle05162  Measles
nle05163  Human cytomegalovirus infection
nle05167  Kaposi sarcoma-associated herpesvirus infection
nle05169  Epstein-Barr virus infection
nle05200  Pathways in cancer
nle05203  Viral carcinogenesis
nle05205  Proteoglycans in cancer
nle05206  MicroRNAs in cancer
nle05212  Pancreatic cancer
nle05221  Acute myeloid leukemia
nle05223  Non-small cell lung cancer
nle05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
nle05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:nle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100598877 (STAT3)
   04066 HIF-1 signaling pathway
    100598877 (STAT3)
   04068 FoxO signaling pathway
    100598877 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100598877 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100598877 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    100598877 (STAT3)
   04062 Chemokine signaling pathway
    100598877 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    100598877 (STAT3)
   04917 Prolactin signaling pathway
    100598877 (STAT3)
   04935 Growth hormone synthesis, secretion and action
    100598877 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100598877 (STAT3)
   05206 MicroRNAs in cancer
    100598877 (STAT3)
   05205 Proteoglycans in cancer
    100598877 (STAT3)
   05203 Viral carcinogenesis
    100598877 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100598877 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    100598877 (STAT3)
   05221 Acute myeloid leukemia
    100598877 (STAT3)
   05223 Non-small cell lung cancer
    100598877 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100598877 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100598877 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100598877 (STAT3)
  09172 Infectious disease: viral
   05162 Measles
    100598877 (STAT3)
   05161 Hepatitis B
    100598877 (STAT3)
   05160 Hepatitis C
    100598877 (STAT3)
   05163 Human cytomegalovirus infection
    100598877 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100598877 (STAT3)
   05169 Epstein-Barr virus infection
    100598877 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100598877 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100598877 (STAT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:nle03000]
    100598877 (STAT3)
Transcription factors [BR:nle03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    100598877 (STAT3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 E2R135 DUF4795 Syntaxin-6_N AP1AR Fib_alpha
Other DBs
NCBI-GeneID: 100598877
NCBI-ProteinID: XP_003279510
Ensembl: ENSNLEG00000011454
UniProt: G1RLB0
LinkDB
Position
Unknown
AA seq 770 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM
NT seq 2313 nt   +upstreamnt  +downstreamnt
atggcccaatggaatcagctacagcagcttgacacacggtacttggagcagctccatcag
ctctacagtgacagcttcccaatggagctgcggcagtttctggccccttggattgagagt
caagattgggcatatgcggccagcaaagaatcacatgccactttggtgtttcataatctc
ctgggagagattgaccagcagtatagccgcttcctgcaagagtcgaatgttctctatcag
cacaatctacgaagaatcaagcagtttcttcagagcaggtatcttgagaagccaatggag
attgcccggattgtggcccggtgcctgtgggaagaatcacgcctcctacagactgcagcc
actgcggcccagcaagggggccaggccaaccaccccacagcagctgtggtgacggagaag
cagcagatgctggaacagcaccttcaggatgtccggaagagagtgcaggatctagaacag
aaaatgaaagtggtagagaatctccaggatgactttgatttcaactataaaaccctcaag
agtcaaggagacatgcaagatctgaatggaaacaaccagtcagtgaccaggcagaagatg
cagcagctggaacagatgctcactgcactggaccagatgcggagaagcatcgtgagtgag
ctggcggggcttttgtcagcgatggagtacgtgcagaaaactctcacggacgaggagctg
gctgactggaagaggcggcaacagattgcctgcattggaggcccgcccaacatctgccta
gatcggctagaaaactggataacgtcattagcagaatctcaacttcagacccgtcaacaa
attaagaaactggaggagttgcagcaaaaagtttcctacaaaggggaccccattgtacag
caccggccgatgctggaggagagaatcgtggagctgtttagaaacttaatgaaaagtgcc
tttgtggtggagcggcagccctgcatgcccatgcatcctgaccggcccctcgtcatcaaa
actggcgttcagttcactaccaaagtcaggttgctggtcaaattccctgagttgaattat
cagcttaaaattaaagtgtgcattgacaaagactctggggacgttgcagctctcagagga
tcccggaaatttaacattctgggcacaaacacaaaagtgatgaacatggaagaatccaac
aatggcagcctctctgcagaattcaaacacttgaccctgagggagcagagatgtgggaat
gggggccgagccaattgtgatgcttccctgattgtgactgaggagctgcacctgatcacc
tttgagaccgaggtgtatcaccaaggcctcaagattgacctagagacccactccttgcca
gttgtggtgatctccaacatctgtcagatgccaaatgcctgggcgtccatcctgtggtac
aacatgctgaccaacaatcccaagaacgtaaacttttttaccaagcccccaattggaacc
tgggatcaggtggctgaggtcctgagctggcaattctcctccaccaccaagcgaggactg
agcatcgagcagctgactacactggcagagaaactcttgggacctggtgtgaattattca
gggtgtcagatcacatgggctaaattttgcaaagaaaacatggctggcaagggcttctcc
ttctgggtctggctggacaatatcattgaccttgtgaaaaagtacatcctggccctttgg
aacgaagggtacatcatgggctttatcagtaaggagcgggagcgggccatcttgagcact
aagcctccaggcaccttcctgctaagattcagtgaaagcagcaaagaaggcggcgtcact
ttcacttgggtggagaaggacatcagtggtaagacccagatccagtccgtggaaccatac
accaagcagcagctgaacaacatgtcatttgctgaaatcatcatgggctataagatcatg
gatgctaccaatatcctggtgtctccgctggtctatctctaccctgacattcccaaggag
gaggcattcggaaagtattgtcggccagagagccaggagcatcctgaagctgacccaggt
agcgctgccccatacctgaagaccaagtttatctgtgtgacaccaacgacctgcagcaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataat
ggtgaaggtgctgaaccctcagcaggagggcagtttgagtccctcacctttgacatggag
ttgacctcggagtgcgctacctcccccatgtga

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