KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100604706Help
Entry
100604706         CDS       T03265                                 

Gene name
GSTO1
Definition
(RefSeq) glutathione S-transferase omega 1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00480  Glutathione metabolism
nle00980  Metabolism of xenobiotics by cytochrome P450
nle00982  Drug metabolism - cytochrome P450
nle00983  Drug metabolism - other enzymes
nle01524  Platinum drug resistance
nle05200  Pathways in cancer
nle05204  Chemical carcinogenesis
nle05225  Hepatocellular carcinoma
nle05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nle00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    100604706 (GSTO1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100604706 (GSTO1)
   00982 Drug metabolism - cytochrome P450
    100604706 (GSTO1)
   00983 Drug metabolism - other enzymes
    100604706 (GSTO1)
 09160 Human Diseases
  09161 Cancers: Overview
   05200 Pathways in cancer
    100604706 (GSTO1)
   05204 Chemical carcinogenesis
    100604706 (GSTO1)
  09162 Cancers: Specific types
   05225 Hepatocellular carcinoma
    100604706 (GSTO1)
  09166 Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    100604706 (GSTO1)
  09176 Drug resistance: Antineoplastic
   01524 Platinum drug resistance
    100604706 (GSTO1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:nle02000]
    100604706 (GSTO1)
Enzymes [BR:nle01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     100604706 (GSTO1)
Transporters [BR:nle02000]
 Other Transporters
  Pores ion channels [TC:1]
   100604706 (GSTO1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N_3 GST_N_2 GST_N GST_C_3 GST_C GST_C_2 Glutaredoxin GST_C_5
Motif
Other DBs
NCBI-GeneID: 100604706
NCBI-ProteinID: XP_003255483
UniProt: G1RZH2
LinkDB All DBs
Position
3
AA seq 241 aa AA seqDB search
MSGESARSLGKGSAPPEPVPEGSIRVYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP
EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF
SKVPSLVGSFIRRQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPW
FERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYG
L
NT seq 726 nt NT seq  +upstreamnt  +downstreamnt
atgtccggggagtcagccaggagcttgggaaagggaagcgcgcccccggagccggtcccg
gagggctcgatccgcgtctacagcatgaggttctgcccgtttgctgagaggacgcgtctg
gtcctgaaggccaagggaatcaggcatgaagtcatcaatatcaacctgaaaaataagcct
gagtggttctttaagaaaaatccctttggtctggtgccagttctggaaaatagtcagggt
cagctgatctacgagtctgccatcacctgtgagtacctggatgaagcatacccagggaag
aagctgttgccggatgacccctatgagaaagcttgccagaagatgatcttagagttgttt
tctaaggtgccatccttggtaggaagctttattagaagacaaaataaagaagactatgct
ggcctaaaagaagaatttcgtaaagaatttaccaagctagaggaggttctgactaataag
aagacgaccttctttggtggcaattctatctctatgattgattacctcatctggccctgg
tttgaacggctggaagcaatgaagttaaatgagtgtgtagaccacactccaaaactgaaa
ctgtggatggcagccatgaaggaagatcccacagtctcagccctgcttactagtgagaag
gactggcaaggtttcctagagctctacttacagaacagccctgaggcctgtgactatggg
ctctga

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