Neisseria meningitidis G2136 (serogroup B): NMBG2136_1020
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Entry
NMBG2136_1020 CDS
T01929
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
nmd
Neisseria meningitidis G2136 (serogroup B)
Pathway
nmd00290
Valine, leucine and isoleucine biosynthesis
nmd00620
Pyruvate metabolism
nmd01100
Metabolic pathways
nmd01110
Biosynthesis of secondary metabolites
nmd01210
2-Oxocarboxylic acid metabolism
nmd01230
Biosynthesis of amino acids
Module
nmd_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
nmd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
NMBG2136_1020 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NMBG2136_1020 (leuA)
Enzymes [BR:
nmd01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
NMBG2136_1020 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
ADY93733
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Position
1032989..1034542
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AA seq
517 aa
AA seq
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MTQANRVIIFDTTLRDGEQSPGAAMTKEEKIRVARQLEKLGVDIIEAGFAAASPGDFEAV
NAIAKTITKSTVCSLSRAIERDIRQAGEAVAPAPKKRIHTFIATSPIHMEYKLKMKPKQV
IEAAVKAVKIAREYTDDVEFSCEDALRSEIDFLAEICGAVIEAGATTINIPDTVGYSIPY
KTEEFFRELIAKTPNGGKVVWSAHCHNDLGLAVANSLAALKGGARQVECTVNGLGERAGN
ASVEEIVMALKVRHDLFGLETGIDTTQIVPSSKLVSTITGYPVQPNKAIVGANAFSHESG
IHQDGVLKHRETYEIMSAESVGWSANRLSLGKLSGRNAFKTKLADLGIELESEEALNAAF
ARFKELADKKREIFDEDLHALVSDEMGNMNTESYKFISQKISTETGEEPRADIVFSIKGE
EKRASATGSGPVDAIFKAIESVAQSGATLQIYSVNAVTQGTESQGETSVRLARGNRVVNG
QGADTDVLVATAKAYLSALSKLEFSAAKPKAQGSGTI
NT seq
1554 nt
NT seq
+upstream
nt +downstream
nt
atgacacaggccaaccgcgttatcattttcgacaccaccctgcgcgacggcgagcagtcg
cccggcgctgctatgaccaaagaggaaaaaatccgcgtcgcccgccagctggaaaaattg
ggtgtggacatcatcgaagcgggttttgccgctgccagcccgggcgatttcgaggcggtc
aatgcgattgcgaaaaccattaccaaatcaacggtctgttcattgtcccgcgccatcgag
cgggacatccgtcaggcgggtgaggccgttgcgcccgcgccgaaaaaacgcatccacacc
ttcatcgccaccagccccatccatatggagtacaaattgaagatgaagccgaagcaggtg
attgaggcggcggtcaaagcggtgaaaatcgctcgtgaatacaccgacgatgtggaattt
tcctgcgaagacgcgttgcgttcggaaatcgatttccttgccgaaatctgcggcgcggta
attgaagcgggcgcgaccaccatcaatattcccgataccgtcggctattccatcccgtac
aaaaccgaagaatttttccgcgaactgattgccaaaacgcccaacggcggcaaagtcgtt
tggtcggcacactgccacaacgatttgggcttggcggttgccaattcgcttgccgcatta
aaaggcggtgcgcgtcaggtggaatgtactgtcaacggcttgggcgaacgtgcaggcaat
gcttcggttgaagaaatcgtgatggcgttgaaagtgcgccacgacttgttcggcttggaa
accggcatcgataccacgcaaatcgtgccttcgtccaaactggtgtccaccattacgggc
tatcccgtgcagcccaacaaagccattgtcggtgccaatgccttttcgcatgaatcgggc
atccatcaggacggggtgctgaaacaccgcgaaacttacgagattatgtctgccgaatcg
gtcggttggtcggctaaccgattgagcttgggcaaattgtccggccgcaacgccttcaaa
accaagctggcggatttgggcatcgagttggaaagcgaagaggcactgaacgcggcattt
gcacgcttcaaagaactcgccgacaaaaaacgcgaaatcttcgatgaagacctgcacgcg
ctggtgtcggacgaaatgggcaatatgaataccgaaagctacaaattcatttcccaaaaa
atcagcaccgaaaccggcgaagagccgcgcgccgacatcgtgttcagcatcaaaggcgaa
gaaaaacgcgcttccgcaaccggttccggtccggttgatgcaattttcaaagcgattgaa
agcgtggcgcaaagcggcgcgactttgcagatttattccgtcaatgccgtcacgcaaggt
acggaaagccaaggcgaaaccagcgtccgtctggcacgcggcaaccgcgtcgtcaacggt
cagggcgcggataccgacgttttggttgccaccgccaaagcctacctttccgccttgagc
aaactggaatttagtgccgccaaaccgaaagcgcaaggcagcggtacgatttga
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