Neisseria meningitidis M01-240355 (serogroup B): NMBM01240355_1925
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Entry
NMBM01240355_1925 CDS
T01947
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
nms
Neisseria meningitidis M01-240355 (serogroup B)
Pathway
nms00230
Purine metabolism
nms01100
Metabolic pathways
nms01110
Biosynthesis of secondary metabolites
Module
nms_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
nms00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
NMBM01240355_1925 (purL)
Enzymes [BR:
nms01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
NMBM01240355_1925 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-ProteinID:
ADZ00399
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All DBs
Position
2114250..2118236
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AA seq
1328 aa
AA seq
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MSVVLPLRGVTALSDFRVEKLLQKAAALGLPEVKLSSEFWYFAGSEKALDAATVEKLQAL
LAAQSVEQTPKAREGLHLFLVTPRLGTISPWASKATNIAENCGLAGIERIERGMAVWLEG
ALTDEQKQQWAALLHDRMTESVLPDFQTASKLFHHLESETFSSVDVLGGGKEALVKANTE
MGLALSADEIDYLVENYQALQRNPSDVELMMFAQANSEHCRHKIFNADFILNGEKQPKSL
FGMIRDTHNAHPEGTVVAYKDNSSVIEGAKIERFYPNAAENQGYRFHEEDTHIIMKVETH
NHPTAIAPFAGAATGAGGEIRDEGATGKGSRPKAGLTGFTVSNLNIPDLKQPWEQDYGKP
EHISSPLDIMIEGPIGGAAFNNEFGRPNLLGYFRTFEEKFDGQVRGYHKPIMIAGGLGSI
QAQQTHKDEIPEGALLIQLGGPGMLIGLGGGAASSMDTGTNDASLDFNSVQRGNPEIERR
AQEVIDRCWQLGGKNPIISIHDVGAGGLSNAFPELVNDAGRGAVFKLRDVPLEEHGLTPL
QIWCNESQERYVLSILEKDLDTFRAICERERCPFAVVGTATDDGHLKVRDDLFANNPVDL
PLNVLLGKPPKTTRTDKTVAPYATEGNPFGKKPFNAGDIDITEAAYRVLRLPAVAAKNFL
ITIGDRSVGGMTHRDQMVGKYQTPVADCAVTMMGFNTYRGEAMSMGEKPTVALFDAPASG
RMCVGEAITNIAAVNIGDIGNIKLSANWMAACGNEGEDEKLYRTVEAVSKACQALDLSIP
VGKDSLSMKTVWQDGEEKKSVVSPLSLIISAFAPVKDVRKTVTPELKNVEDSVLLFIDLG
FGKARMGGSAFGQVYNNMSGDAPDLDDTSRLKAFYNVIQQLVAEDKLLAYHDRSDGGLFA
VLVEMAFAGRCGLDIDLNLLLAQTFITNHTALSQSLRTEEVKALAEWQETIARTLFNEEL
GAVIQVRKQDVADIINLFYQQQLHHNVFEIGTLTDENTLIIRDGQTHLISDNLIKLQQTW
QETSHQIQRLRDNPACADSEFALIGDNGRSALFANLKFDVNEDIAAPFINSGAKPKIAIL
REQGVNGQIEMAAAFTRAGFDAYDVHMSDLMAGRIHLADFKMLAACGGFSYGDVLGAGEG
WAKSILFHPALRDQFAAFFADPDTLTLGVCNGCQMVSNLAEIIPGTAGWPKFKRNLSEQF
EARLSMVHVPKSASLILNEMQGSSLPVVVSHGEGRADFALHGGNISADLGIALQYVDGQN
QVTQTYPLNPNGSPQGIAGITNADGRVTIMMPHPERVYRAAQMSWKPEGWTELSGWYRLF
AGARKALG
NT seq
3987 nt
NT seq
+upstream
nt +downstream
nt
atgtctgtcgttttgcccttgcgcggcgttaccgccctttccgatttccgtgtcgaaaaa
ctcttgcaaaaagccgccgcactcggactgcccgaagtcaaattaagcagcgaattttgg
tatttcgccggcagcgagaaagcattggatgccgcgactgtcgaaaaactgcaagccttg
ttggcggcgcaaagcgttgaacaaacgccaaaagcgcgcgagggcttgcatttgtttttg
gtcacgccccgtttgggtacgatttcgccgtgggcttccaaggcgaccaatatcgcggaa
aactgcggtttggcaggcatcgagcgcatcgagcgcggcatggcggtgtggctggaaggt
gcgcttaccgatgaacagaaacagcaatgggcggctttgctgcacgaccgcatgaccgaa
tccgtattgcccgattttcagacggcctccaaattattccaccatctcgaatccgaaact
ttctccagcgtcgatgttttgggcggcggtaaagaggctttggtcaaagccaataccgaa
atgggcttggcactttcagccgacgaaatcgattatctggttgaaaactaccaggctttg
cagcgcaatccgtccgatgttgaattgatgatgttcgcgcaggcaaacagcgaacactgc
cgccacaaaatcttcaacgccgacttcatcctcaacggcgaaaaacaaccgaaatccctg
ttcggtatgatacgcgacacgcacaacgcgcatcccgaaggcacggtcgtcgcttataaa
gacaactcgtccgtaattgaaggcgcgaaaatcgagcgtttctatccgaatgcggcggaa
aaccaaggttaccgtttccacgaagaagacacgcatatcatcatgaaagtggaaacgcac
aaccacccgaccgccatcgcgccgtttgcgggcgcggcaacaggcgcgggcggcgaaatc
cgcgacgaaggcgcaacgggcaaaggttcgcgtccgaaagcaggcttgaccggctttacc
gtctccaacctcaacatccccgacctcaaacagccgtgggaacaagactacggcaagccg
gaacacatttcctccccgttggacatcatgattgaaggccccatcggcggcgcggcgttc
aacaacgaattcggccgccccaacctcttgggctacttccgcacttttgaagagaagttt
gacggtcaggttcgcggctaccacaaaccgattatgattgccggcggcttgggcagcatt
caggcgcagcagacgcataaagacgaaatccccgaaggcgcgttgctgatccaactgggc
ggcccgggcatgcttatcggcttgggcggcggcgcggcttcttcgatggataccggcacg
aacgacgcgtctttagacttcaattccgtacaacgcggcaaccccgaaatcgaacgccgc
gcgcaggaagtcatcgaccgctgctggcagctcggcggcaaaaacccgattatctccatc
cacgacgtgggcgcaggaggtttgtccaacgccttccccgaactggtcaacgatgccgga
cgcggcgcggtattcaagctgcgcgacgtgccgctggaagaacacggtttaacgcctttg
caaatctggtgcaacgaatcgcaagagcgttatgtgttgtcgattttggaaaaagatttg
gacaccttccgcgccatctgcgaacgcgaacgctgcccgtttgccgtggttggcacggcg
accgacgacggccatttgaaagtgcgcgacgatttgttcgccaacaaccccgtcgatttg
ccgctgaacgtcttgctcggcaaaccgcccaaaaccacgcgtaccgacaaaacggttgcg
ccgtatgcgaccgaagggaatccctttgggaaaaaaccgtttaacgccggcgatatcgac
attaccgaagccgcctaccgcgttttgcgcctgcctgccgtagccgccaaaaacttcctg
attaccatcggcgaccgcagcgtcggcggcatgacccaccgcgaccaaatggtcggcaaa
taccaaacccccgtagccgactgcgccgttaccatgatgggcttcaatacctatcgcggc
gaagcgatgtctatgggcgaaaaaccgaccgttgccctgtttgacgcgcctgcttcaggc
agaatgtgcgtcggcgaagccatcaccaacatcgcggcggtcaacatcggcgacatcggc
aacatcaagctctccgccaactggatggcggcgtgcggcaacgagggcgaagacgaaaaa
ctctaccgcaccgtcgaagcggtttccaaagcctgtcaggcattggatttgagcattccc
gtgggcaaagacagcctgtcgatgaaaactgtgtggcaggacggcgaagagaaaaaatcc
gtcgtctcgccattgagcctgattatctctgcgttcgcgccggtcaaagacgtgcgcaaa
accgttacgcccgaattgaaaaacgtcgaagacagcgtattgttatttatcgatttgggc
ttcggcaaagcgcgtatgggcggctctgcattcggtcaggtatacaacaacatgagcggc
gacgcgcccgatttggacgatacaagtcgtctgaaagcgttttacaacgtgattcaacag
cttgtcgccgaagacaaactcttggcataccacgaccgcagcgacggcggtttgtttgcc
gttttggtagaaatggcgtttgcggggcggtgcggcttggatatagatttaaatttattg
cttgcacaaacatttattaccaaccataccgctctgtctcaatcattgcggactgaagag
gtaaaagcgttggctgaatggcaagaaaccattgcccgcacattatttaatgaagagttg
ggtgctgttatccaagttagaaaacaagatgttgccgatattatcaatttattctatcaa
caacagctgcatcataatgtctttgaaatcggtacgttaactgatgagaacacgttaatc
atccgcgacgggcaaacgcaccttatttctgacaacctaatcaaactgcaacaaacctgg
caagaaaccagccatcaaatccaacgcctgcgcgacaaccccgcctgcgccgacagcgag
ttcgcattgattggcgacaacggacgcagcgcattgtttgccaacctgaaattcgacgtg
aacgaagacatcgccgcgccgtttatcaacagcggcgcgaaacccaaaatcgccatcctg
cgcgaacagggcgtaaacgggcaaatcgaaatggccgccgcctttacccgcgccggattc
gatgcttacgacgtgcatatgtccgacctgatggcaggccgcatccacctcgccgacttc
aaaatgctggcggcgtgcggcggcttcagctacggcgacgtactcggcgcgggcgaaggc
tgggcgaaatcgattctgttccaccctgctctgcgcgaccagtttgccgccttcttcgcc
gacccggacacgctgacattgggcgtgtgcaacggctgccaaatggtcagcaaccttgcc
gaaatcatccccggcacggcaggctggccgaagttcaaacgcaacctgagcgaacagttt
gaagcgcgcctaagcatggttcacgtccccaaatccgcgtcgctgattctgaacgaaatg
caaggctccagcctgcccgtcgtcgtcagccacggcgaaggccgcgccgacttcgcactt
cacggcggcaacatttctgccgatttgggcattgcgctgcaatatgtggacggtcaaaac
caagttacccaaacctatccgctcaaccccaacggctcgccgcaaggcatcgccggcatt
accaacgccgacggccgcgtgaccatcatgatgccccaccccgaacgcgtgtaccgcgcc
gcacaaatgagctggaaaccggaaggctggacggaactgtccggctggtaccgcctcttt
gccggcgcacgtaaagccttgggctaa
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