KEGG   Neisseria meningitidis 8013 (serogroup C): NMV_2280
Entry
NMV_2280          CDS       T01928                                 
Symbol
folD
Name
(GenBank) FolD bifunctional protein (PPDC) [includes: methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase]
  KO
K01491  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
Organism
nmt  Neisseria meningitidis 8013 (serogroup C)
Pathway
nmt00670  One carbon pool by folate
nmt01100  Metabolic pathways
nmt01120  Microbial metabolism in diverse environments
nmt01200  Carbon metabolism
nmt01240  Biosynthesis of cofactors
Module
nmt_M00140  C1-unit interconversion, prokaryotes
Brite
KEGG Orthology (KO) [BR:nmt00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    NMV_2280 (folD)
Enzymes [BR:nmt01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     NMV_2280 (folD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     NMV_2280 (folD)
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH OCD_Mu_crystall AlaDh_PNT_C
Other DBs
NCBI-ProteinID: CAX51036
UniProt: A0A9K2KQQ8
LinkDB
Position
2204156..2205010
AA seq 284 aa
MSAQLINGKEVSQKRLQAVAEAVAQRQQDNLHTPCLAVVLVGGDPASAVYVRNKKTACQK
CGIKSLSYELPESTSQEELLALVDRLNADSEVDGILVQLPLPKHLDSQAVLERISPDKDV
DGFHPYNVGRLAVKMPLMRPCTPKGVMTLLEAYGIDPKGKKAIVVGASNIVGRPQALELL
LARATVTVCHSATENLADEVAGADILVVGVGIPNFVKGEWIKPGAVVIDVGINRLDDGSL
CGDVEFETAKERAAMITPVPGGVGPMTIATLMENTLHAASLHDA
NT seq 855 nt   +upstreamnt  +downstreamnt
atgtcggcacaactgatcaatggtaaagaagtttcgcaaaaacgcctgcaggcggttgcc
gaagcggtggcgcaacgccaacaggacaatctgcacacgccttgcctggccgtggttttg
gtcggaggcgaccctgccagcgcggtttatgtccgcaacaagaaaactgcctgccaaaaa
tgcggcatcaaatcactgtcttacgagctgcccgaatcaacatcgcaggaagaactgctg
gcactggtcgaccgcctgaatgccgattccgaagtggacggtattctggttcagctaccg
ctgccgaagcacctcgacagccaggcggttttggaacgtatttcgccggataaggacgtg
gacggcttccatccttacaatgtcggcaggctggcggtcaaaatgccgctgatgcgcccg
tgtacgcccaagggcgtgatgacgcttttggaagcttacggcattgatccgaaggggaaa
aaagcgatcgtggtcggcgcgtcgaatatcgtcggccgcccgcaggcgttggaattgctg
ctggcacgcgcaacggtaacggtctgccacagcgcaaccgaaaatctggcagacgaggtt
gccggagccgatattttggtggtcggcgtgggcattccgaactttgtcaaaggcgaatgg
atcaaacccggcgcggtcgttatcgatgtgggcatcaaccgtttggacgacggcagcctg
tgcggcgacgtggaatttgaaacggcaaaagaacgggcggcgatgattacgcccgttccc
ggcggcgtgggtccgatgacgattgccacattgatggaaaacaccctgcacgcggcttca
ctgcacgatgcttga

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