KEGG   Ornithorhynchus anatinus (platypus): 100085901
Entry
100085901         CDS       T01045                                 

Gene name
ADCY3
Definition
(RefSeq) LOW QUALITY PROTEIN: adenylate cyclase type 3
  KO
K08043  adenylate cyclase 3 [EC:4.6.1.1]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa00230  Purine metabolism
oaa01100  Metabolic pathways
oaa01522  Endocrine resistance
oaa04015  Rap1 signaling pathway
oaa04020  Calcium signaling pathway
oaa04022  cGMP-PKG signaling pathway
oaa04024  cAMP signaling pathway
oaa04062  Chemokine signaling pathway
oaa04072  Phospholipase D signaling pathway
oaa04114  Oocyte meiosis
oaa04211  Longevity regulating pathway
oaa04213  Longevity regulating pathway - multiple species
oaa04261  Adrenergic signaling in cardiomyocytes
oaa04270  Vascular smooth muscle contraction
oaa04371  Apelin signaling pathway
oaa04540  Gap junction
oaa04611  Platelet activation
oaa04713  Circadian entrainment
oaa04714  Thermogenesis
oaa04723  Retrograde endocannabinoid signaling
oaa04724  Glutamatergic synapse
oaa04725  Cholinergic synapse
oaa04727  GABAergic synapse
oaa04740  Olfactory transduction
oaa04750  Inflammatory mediator regulation of TRP channels
oaa04911  Insulin secretion
oaa04912  GnRH signaling pathway
oaa04913  Ovarian steroidogenesis
oaa04914  Progesterone-mediated oocyte maturation
oaa04915  Estrogen signaling pathway
oaa04916  Melanogenesis
oaa04918  Thyroid hormone synthesis
oaa04921  Oxytocin signaling pathway
oaa04923  Regulation of lipolysis in adipocytes
oaa04925  Aldosterone synthesis and secretion
oaa04926  Relaxin signaling pathway
oaa04927  Cortisol synthesis and secretion
oaa04928  Parathyroid hormone synthesis, secretion and action
oaa04934  Cushing syndrome
oaa04935  Growth hormone synthesis, secretion and action
oaa04962  Vasopressin-regulated water reabsorption
oaa04970  Salivary secretion
oaa04971  Gastric acid secretion
oaa04972  Pancreatic secretion
oaa04976  Bile secretion
oaa05032  Morphine addiction
oaa05163  Human cytomegalovirus infection
oaa05166  Human T-cell leukemia virus 1 infection
oaa05200  Pathways in cancer
oaa05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100085901 (ADCY3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100085901 (ADCY3)
   04371 Apelin signaling pathway
    100085901 (ADCY3)
   04020 Calcium signaling pathway
    100085901 (ADCY3)
   04072 Phospholipase D signaling pathway
    100085901 (ADCY3)
   04024 cAMP signaling pathway
    100085901 (ADCY3)
   04022 cGMP-PKG signaling pathway
    100085901 (ADCY3)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100085901 (ADCY3)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    100085901 (ADCY3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100085901 (ADCY3)
   04062 Chemokine signaling pathway
    100085901 (ADCY3)
  09152 Endocrine system
   04911 Insulin secretion
    100085901 (ADCY3)
   04923 Regulation of lipolysis in adipocytes
    100085901 (ADCY3)
   04912 GnRH signaling pathway
    100085901 (ADCY3)
   04913 Ovarian steroidogenesis
    100085901 (ADCY3)
   04915 Estrogen signaling pathway
    100085901 (ADCY3)
   04914 Progesterone-mediated oocyte maturation
    100085901 (ADCY3)
   04921 Oxytocin signaling pathway
    100085901 (ADCY3)
   04926 Relaxin signaling pathway
    100085901 (ADCY3)
   04935 Growth hormone synthesis, secretion and action
    100085901 (ADCY3)
   04918 Thyroid hormone synthesis
    100085901 (ADCY3)
   04928 Parathyroid hormone synthesis, secretion and action
    100085901 (ADCY3)
   04916 Melanogenesis
    100085901 (ADCY3)
   04925 Aldosterone synthesis and secretion
    100085901 (ADCY3)
   04927 Cortisol synthesis and secretion
    100085901 (ADCY3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100085901 (ADCY3)
   04270 Vascular smooth muscle contraction
    100085901 (ADCY3)
  09154 Digestive system
   04970 Salivary secretion
    100085901 (ADCY3)
   04971 Gastric acid secretion
    100085901 (ADCY3)
   04972 Pancreatic secretion
    100085901 (ADCY3)
   04976 Bile secretion
    100085901 (ADCY3)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    100085901 (ADCY3)
  09156 Nervous system
   04724 Glutamatergic synapse
    100085901 (ADCY3)
   04727 GABAergic synapse
    100085901 (ADCY3)
   04725 Cholinergic synapse
    100085901 (ADCY3)
   04723 Retrograde endocannabinoid signaling
    100085901 (ADCY3)
  09157 Sensory system
   04740 Olfactory transduction
    100085901 (ADCY3)
   04750 Inflammatory mediator regulation of TRP channels
    100085901 (ADCY3)
  09149 Aging
   04211 Longevity regulating pathway
    100085901 (ADCY3)
   04213 Longevity regulating pathway - multiple species
    100085901 (ADCY3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100085901 (ADCY3)
   04714 Thermogenesis
    100085901 (ADCY3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100085901 (ADCY3)
  09165 Substance dependence
   05032 Morphine addiction
    100085901 (ADCY3)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    100085901 (ADCY3)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100085901 (ADCY3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100085901 (ADCY3)
   05163 Human cytomegalovirus infection
    100085901 (ADCY3)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100085901 (ADCY3)
Enzymes [BR:oaa01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     100085901 (ADCY3)
SSDB
Motif
Pfam: Guanylate_cyc AC_N
Other DBs
NCBI-GeneID: 100085901
NCBI-ProteinID: XP_028908727
LinkDB
Position
X2
AA seq 1193 aa
MSPPRAFPEPEYSADWSVSLPSEAERGPHAPTARRPREVTGGGSGPCPRPPGSVRLAFVP
ASLERLYQTYFRRQRHDTLPVLGIFAALFDCYVLLTCGPAFSPDRAAPLAVAGGGLLLAA
PLLVPLGKGPPAARPARLARRAGPYLLWLLVVAQIFCYLGLAFFRAHAVGDAAGWLAFFV
FSSFVTLPLGLAPLVLVSGAPCALHTLVLGVAVARRRRERPDGAEPLREVLANVVIYLCA
IAVGIMSYYMADRKHRKAFLEARQSLEVKINLEEQGQQQESLMLSILPKHVADEMLKDMK
RDKTQKELQQFNTMYMYRHENVSILFADIVGFTQLSSTCSAQELVKLLNELFARFDKLAA
KYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVDAISYVREKTQTGVDMRVGVH
TGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTLDCLKGEXEVEPGNGG
QPVHYLEEKGIVTYLIRASGPARPRPEWPSTCGEGPPGAGADGGGGPPRPPTSDRVVPLP
AKEQNGSVNTTCSSPRQPLDPAPQVVNPSFPNPRRRLRLRDLAEGWVDASEHEHELNQLL
NEPSWSGSRAQGVGAKGRTTFLLSIRFVDPELESRYSVEKEKQSGPRSAVPAWFLFCTAL
VWLMANTWTFVVGEGLLLILTVGSLAAIFPGKVFPEKLVAFSTWIDRTRWARNTWAMAAI
IILIMADLLSCLNRSGDPGNWTAAGGCAANPKYSSYVAVLTLIATVMLVQVSHMVKLTLM
LLLLVGVGVVNIYAWHPAFDRYDRQQLREHGSSPHLNSPENRAPFPGPLNGTSSLPLVPS
KYSMTAMIFVMMLSFYYFSRHVERLARTLSCGKMEVHDQKERVYEMRRLERGLVTNMLPD
HVGPTLPGLQEEDEVRTPTPRHPPGPPGGSRAHRHVAGPPGVDGSGPRRALLALLLPCPQ
ELYSQAYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDFDSLLDNPQFRIIT
KIKTIGSTYMAASGVTPEANTNGFTSASKEGQSDKERWQHLADLADFALAMKDTLTSINN
QSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGNIQVVEETQDI
LRTFGFRFVRRGRVFVKGKGELLTFFLKGREKVAPFPNGSSSVTLPHQVVDCS
NT seq 3582 nt   +upstreamnt  +downstreamnt
atgtcgccgccccgcgccttcccggagcccgagtattcggccgactggtcggtgagcctg
ccctccgaggcggagcggggtccccacgcccccaccgcccggcgaccccgcgaggtgacg
gggggcgggtcgggcccctgcccgcgcccgcccggctccgtgcggctggccttcgtcccc
gcctccctggagaggctctaccagacctacttcagacggcagcgccacgacaccctgccg
gtgctgggcatcttcgccgcgctcttcgactgctacgtcctgctcacgtgcggcccggcc
ttctcccccgaccgggcggcccccttggcggtggcgggcggggggctgctgctggccgcc
ccgctgctcgtccccctcgggaaggggcccccggccgcccgcccggcccgcctggcccgc
cgggccggtccctacctgctgtggctgctcgtcgtcgcccagatattctgctacctgggc
ctggccttcttccgcgcccacgcggtcggcgacgcggcgggctggctggccttcttcgtc
ttctcgtccttcgtcacgctgcccctcgggctggcgcccctggtgctggtgtccggggcc
ccctgcgccctccacaccttggtcctgggcgtcgccgtcgcgcggcggcggcgggagcgg
ccggacggggccgagccgctgagagaggtcctggccaatgtggtcatctacctctgcgcc
atcgccgtgggcatcatgtcctactacatggccgaccgcaagcaccgcaaggcctttctg
gaggctcgccagtccctcgaggtcaagatcaacctggaggaacaggggcagcagcaggaa
agcctgatgctgtccatcttgcccaaacacgtggcagacgagatgctgaaggacatgaag
agggataagacgcagaaggagctgcagcagttcaacaccatgtacatgtaccgacacgag
aacgtcagcatcctgtttgcggacatcgtgggcttcacgcagctgtcttccacctgcagc
gcccaggaactggtcaagctcctcaatgagctgttcgcccgtttcgataagctggcggcc
aaataccaccagctgcggatcaagatcctgggcgattgttactactgcatctgcgggctc
ccggactaccgagaggaccacgccgtctgctccatcctcatggggctcgccatggtggac
gccatctcgtatgtgcgggagaagacgcagaccggggtggacatgcgagtcggggtgcac
acgggcacggtgctgggcggcgtgctggggcagaaacgctggcagtacgacgtctggtcc
acggacgtcaccgtcgccaacaaaatggaagccgggggcatcccggggcgggtgcacatc
tcccagagcaccctggactgcctgaagggcgagntcgaggtggagccgggcaacgggggg
cagccggtgcactatctggaggagaaggggatcgtcacctacctcatccgcgcgtccggg
ccggcccggccgcggccagagtggccgtcaacgtgtggtgagggaccgccgggcgcgggg
gcggatgggggcggggggcccccgcgcccaccgacctctgaccgcgtggtgcctctgccc
gccaaagagcagaacgggagcgtcaacaccacctgctccagcccccggcagccccttgac
cctgccccacaggtggttaacccttccttccccaatccccgtcggcgcctgcgcctgcgc
gacttggccgaagggtgggtcgacgcctccgagcacgaacacgagctcaatcagctgctc
aacgagccctcctggagcgggagtcgggcccaaggggtgggggcaaagggcaggaccacc
ttcctgctgtccatccgcttcgtggatccggagctggagagccgctactctgtggagaag
gagaaacagagtgggccgcgttcagctgttcctgcgtggtttctcttctgcacggccctc
gtctggctgatggccaatacgtggaccttcgtggtgggggaggggctcctgctgatcctg
accgtgggttccctggcggccatcttccccggtaaggtgttccccgagaagctggtggcc
ttctccacctggatcgacaggacacgctgggccaggaacacttgggctatggcggccatc
atcatcctcatcatggccgaccttctcagctgcctgaaccgctccggggatcccggcaac
tggacggcggcaggcggctgtgccgcgaaccccaaatactccagctacgtcgcggtcctg
accctgatcgccaccgtcatgctggtgcaggtcagccacatggtcaagctcaccctcatg
ctgctgctcttggtgggcgtgggcgtggtcaacatctacgcctggcaccccgccttcgac
cggtacgaccgccagcagctccgggagcacggcagctcgccccacctcaacagcccggag
aatcgggcgccgtttcccggcccgctcaacggcaccagcagcctgcccctggtcccctcc
aagtactcgatgacggcgatgatcttcgtaatgatgctgagtttttactatttctctcgc
catgtggagaggctggcgcggacgctgtcctgtggaaagatggaggtgcacgaccagaag
gagcgcgtctacgagatgcggcgcctggaacgaggcctggtcaccaacatgctgccggac
cacgtgggcccgacacttcctgggctccaagaagaggatgaggtgaggacccccaccccc
cgacatcccccgggcccgccggggggctcccgcgctcaccgacacgtggcggggcctccc
ggcgtcgacgggagcggcccccgccgggccctcctcgctctccttctcccgtgtccccag
gaactctacagtcaggcctacgacgagatcggggtcatgttcgcttcgctgcccaacttc
gccgacttctacacggaggagagcatcaacaacggcggcatcgagtgcctgcgcttcctc
aatgagattatctccgacttcgactccctcctagacaaccctcagttccggatcatcacc
aagatcaagaccatcggcagcacctacatggccgcatccggggtcaccccagaggccaac
accaacggctttaccagcgccagcaaggagggccagtcggacaaggagcgctggcagcac
ctggccgacctggccgacttcgccctggccatgaaggacacgctgaccagcatcaacaac
cagtctttcaacaacttcatgctgagaatcggtatgaacaaaggcggggttctggcaggg
gtcatcggcgcccgcaagccccactacgatatctgggggaacacggttaacgtggccagc
aggatggagtccaccggggtcatgggcaacatccaggtggtggaggagacgcaggacatc
ctccggacgttcggcttccgcttcgtgcggcgcggccgtgtcttcgtcaagggcaaaggg
gagctgctgaccttcttcctcaaggggcgggagaaggtggcccctttccccaacggcagc
tcctccgtcaccctgccgcaccaggtggtcgactgctcctga

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