KEGG   Ovis aries (sheep): 100192422
Entry
100192422         CDS       T03117                                 

Gene name
MMP9
Definition
(RefSeq) matrix metalloproteinase-9
  KO
K01403  matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
Organism
oas  Ovis aries (sheep)
Pathway
oas01522  Endocrine resistance
oas04657  IL-17 signaling pathway
oas04668  TNF signaling pathway
oas04670  Leukocyte transendothelial migration
oas04915  Estrogen signaling pathway
oas04926  Relaxin signaling pathway
oas05161  Hepatitis B
oas05200  Pathways in cancer
oas05202  Transcriptional misregulation in cancer
oas05205  Proteoglycans in cancer
oas05206  MicroRNAs in cancer
oas05215  Prostate cancer
oas05219  Bladder cancer
oas05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    100192422 (MMP9)
 09150 Organismal Systems
  09151 Immune system
   04657 IL-17 signaling pathway
    100192422 (MMP9)
   04670 Leukocyte transendothelial migration
    100192422 (MMP9)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    100192422 (MMP9)
   04926 Relaxin signaling pathway
    100192422 (MMP9)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100192422 (MMP9)
   05202 Transcriptional misregulation in cancer
    100192422 (MMP9)
   05206 MicroRNAs in cancer
    100192422 (MMP9)
   05205 Proteoglycans in cancer
    100192422 (MMP9)
  09162 Cancer: specific types
   05219 Bladder cancer
    100192422 (MMP9)
   05215 Prostate cancer
    100192422 (MMP9)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    100192422 (MMP9)
  09172 Infectious disease: viral
   05161 Hepatitis B
    100192422 (MMP9)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100192422 (MMP9)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:oas01002]
    100192422 (MMP9)
Enzymes [BR:oas01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.35  gelatinase B
     100192422 (MMP9)
Peptidases and inhibitors [BR:oas01002]
 Metallo peptidases
  Family M10
   100192422 (MMP9)
SSDB
Motif
Pfam: Peptidase_M10 fn2 Hemopexin PG_binding_1 PT Reprolysin_4 DUF4953 Reprolysin_3
Other DBs
NCBI-GeneID: 100192422
NCBI-ProteinID: XP_004014663
Ensembl: ENSOARG00000007908
UniProt: A0A6P3E9E1
LinkDB
Position
13
AA seq 709 aa
MSPRQPLVLALLVLACCSAAPSPRQPTVVVFPGERRTSLTNRQLAEEYLYRYGYTPAAEL
SEDGQSLRRALLSFQRRLSLPETGELDSTTLDAMRAPRCGVPDLGGFQTFEGELKWHHHN
ITYWIQNYSEDLPRDVIDDAFARAFALWSAVTPLTFTRVYGREADIVIQFGVREHGDGYP
FDGKNGLLAHAFPPGSGIQGDAHFDDEELWSLGKGVVIPTYFGNAKGAACHFPFTFEGRS
YSSCTTDGRSDDMLWCSTTADYDADRQFGFCPSERLYTQDGNADGKPCVFPFTFEGRTYS
ACTSDGRSDGYRWCATTANYDQDKLYGFCPTRVDATVTGGNAAGELCVFPFTFLGKEYSA
CTREGRNDGHLWCATTSNFDKDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMY
PMYRFTEEHPLHRDDVQGIQHLYGPRPEPEPRPPATTTAEPQPTAPPTVCVTGPPTARPS
EGPTTGPTGPPAAGPTGPPTAGPSAAPTESPDPAEDVCNVDIFDAIAEIGNRLHFFKAGK
YWKLSGGGGRRVQGPFLVKSTWPALPRKLDSAFEDPLTKKIFFFSGRQVWVYTGASVLGP
RRLDKLGLGPEVAQVTGALPRPGGKVLLFSGQSFWRFDVKTQKVDPQSVTPVDQMFPGVP
ISTHDIFQYQEKAYFCQDHFFWRVSSRNEVNQVDYVGYVTFDLLKCPED
NT seq 2130 nt   +upstreamnt  +downstreamnt
atgagcccccggcagcccttggtcctggcactcctggtgctagcctgctgctctgccgcc
cccagcccacgccagcccaccgttgtggtcttcccaggagaacgacgaaccagcctcacc
aacaggcagctggcagaggaatacctgtaccgctatggctacactcctgcggcagagctg
agcgaggacggccagtccctgcggcgagctctgctgagcttccagcgccgcctgtccctg
cccgagactggcgagctggacagcaccaccctggacgccatgcgagccccgcgctgcggc
gtcccagacctgggcggattccagacctttgagggcgaactcaagtggcaccatcacaac
atcacctactggatccaaaattactcggaagacctgccgcgcgacgtgattgacgacgcc
tttgcccgcgctttcgcgctctggagcgcggtgacgccgctcacctttactcgagtatac
ggccgcgaagccgacatcgtcatccagtttggtgttagagagcacggagatgggtatccc
ttcgatggaaagaacgggctcctggcacacgcctttcctcctggctcaggcattcaggga
gatgcccacttcgacgatgaagagttatggtctctgggcaaaggcgttgtgatcccgacc
tacttcggaaacgcgaagggcgccgcctgccacttccccttcaccttcgagggccgctcc
tactcctcctgcaccacggacggccgttccgacgacatgctctggtgcagcaccaccgct
gactacgacgccgaccgccagttcggcttctgccccagcgagagactctacacccaggac
ggcaatgcggacggcaagccctgcgtcttcccgttcaccttcgagggccgcacctactcc
gcctgtacctccgatggtcgctccgacggctaccgctggtgcgccaccactgctaactac
gaccaggacaagctctacggcttctgcccgacccgagtcgatgcgacggtgaccgggggc
aacgcggcgggagagctgtgcgtcttccccttcaccttcctgggcaaggaatactcggcc
tgcaccagagagggtcgcaatgatgggcacctctggtgcgccaccacctccaacttcgac
aaagacaagaagtggggcttctgcccggatcaaggatacagcctgttccttgtggccgca
cacgagtttggccacgcgctgggcttagatcactcctccgtgccagaggcgctcatgtac
cccatgtacagattcaccgaggagcaccccctgcatagggacgatgttcagggcatccag
catctgtatggtcctcgccctgagcctgaaccacggcctccggccaccaccaccgccgaa
ccccagcccaccgctcccccaacggtctgcgtcacggggcctcccaccgcccgcccctca
gagggccccactactggccccacagggcccccggcagctggccccacgggtcctcccacg
gcaggcccttctgcggccccgacagagtccccggatccagcggaggacgtctgcaacgtg
gacatcttcgacgccatcgcggagattgggaaccgcctgcatttcttcaaggctgggaag
tactggaaactctctgggggagggggccgccgggtgcagggtccctttcttgtcaagagc
acgtggcctgcgctgccccgaaagctggactccgccttcgaggatccgctcaccaagaag
attttcttcttctctgggcgccaagtgtgggtgtacaccggcgcgtcggtgctaggcccg
aggcgtctggacaagttgggcctgggcccggaagtggcccaggtcaccggggccctcccg
cgccctgggggtaaggtgctgctgttcagcgggcagagcttctggaggttcgacgtgaag
acacagaaggtggatccccagagcgtcacccccgtggaccagatgttccccggggtgccc
attagcacgcacgacatctttcagtaccaagagaaagcttacttctgccaggatcacttc
ttctggcgtgtgagttcccggaatgaggtgaatcaggtggactatgtgggctacgtgacc
ttcgacctcctgaagtgccctgaggactag

KEGG   Ovis aries (sheep): 101118895
Entry
101118895         CDS       T03117                                 

Definition
(RefSeq) stromelysin-1
  KO
K01394  matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
Organism
oas  Ovis aries (sheep)
Pathway
oas04657  IL-17 signaling pathway
oas04668  TNF signaling pathway
oas05171  Coronavirus disease - COVID-19
oas05202  Transcriptional misregulation in cancer
oas05215  Prostate cancer
oas05323  Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:oas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    101118895
 09150 Organismal Systems
  09151 Immune system
   04657 IL-17 signaling pathway
    101118895
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    101118895
  09162 Cancer: specific types
   05215 Prostate cancer
    101118895
  09163 Immune disease
   05323 Rheumatoid arthritis
    101118895
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    101118895
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:oas01002]
    101118895
Enzymes [BR:oas01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.17  stromelysin 1
     101118895
Peptidases and inhibitors [BR:oas01002]
 Metallo peptidases
  Family M10
   101118895
SSDB
Motif
Pfam: Peptidase_M10 Hemopexin PG_binding_1 Astacin Reprolysin_3 Reprolysin_4 DUF4953 Reprolysin_5
Other DBs
NCBI-GeneID: 101118895
NCBI-ProteinID: XP_004016019
Ensembl: ENSOARG00000005084
UniProt: A0A6P3EK35
LinkDB
Position
15
AA seq 477 aa
MRSLPILLSLCVAVCSAYPLDRAARDKEDSMELVQQYLENYYNLAKDTKQFVRRKDSSPV
VKKIQEMQKFLGLEVTGKLDSDTLEVIRKPRCGIPDVSSFSTFPGMPKWRKTHLTYRIVN
YTKDLPRDAVDSAIEKALTVWEEVTPLTFSRIYEGEADIMIMFAVREHGDFLPFDGPGKV
LAHAYPPGSGFYGDAHFDDDEQWTKDTSGINLFLVAAHEFGHSLGLQHSTEREALMYPVY
DPLTDLTRFRLSQDDINGIQFLYGSPLVSPNDPVVPTESVPPEPGTPAACDPALSFDAIS
TLRGEILFFKGRHFWRKSFRTLEPEFHLISSFWPSLPSGIDAAYEVTSKDTVFIFKGNQF
WAIRGNEMQAGYPRGIHTLGLPSTVRKIDAAFSDKEKKKTYFFAEDKYWRFDEKRQSMEP
GFPKQIVEDFPGVEPEVDAVFKVFGFYYFFSGSSQFEFDPNAKKVTHVLKSNSWLNC
NT seq 1434 nt   +upstreamnt  +downstreamnt
atgagaagccttccaattctgctgtcgctatgtgtggcagtgtgctcagcctatccactg
gacagggctgcaagggacaaggaagacagcatggagcttgttcagcaatatctagaaaac
tactacaaccttgcaaaggatacgaaacagtttgttagaaggaaggacagtagtccagta
gtcaaaaagattcaagagatgcagaagtttctggggttggaggtgacaggaaagctggac
tctgacaccctggaggtgatacgcaagccccgatgtgggattcctgatgtcagttccttc
agcacctttcctggtatgcccaagtggaggaaaactcaccttacctacagaattgtgaat
tacacaaaggatttacccagagatgctgttgattctgccattgaaaaagctctgacggtc
tgggaggaggtgactccacttacattctccaggatctatgaaggagaagctgacataatg
atcatgtttgcagttagagaacatggggactttttgccttttgatggacctggaaaagtt
ttggctcatgcctatccacctggatcagggttttatggagatgctcactttgatgatgat
gaacaatggacaaaggatacatcaggaatcaatttattccttgttgctgcccatgaattt
ggccattccctgggtctccaacactcaaccgaacgtgaagctttgatgtacccagtctac
gaccctctcacagacctcactcggttccgcctctctcaggatgatatcaacggcattcag
ttcctgtacgggtctcccctagtttcccctaatgaccccgtggtgcccacggaatctgtg
cctccggagcccgggaccccagctgcgtgtgatcctgccttgtccttcgatgcaatcagc
acactgaggggagaaatcctgttctttaaaggcagacatttttggcggaaatctttcagg
acactcgaacctgaatttcatttgatctcttcattctggccatctcttccttcaggcata
gatgccgcatatgaagttactagcaaagacacggttttcatttttaaaggaaatcagttc
tgggccatcagaggcaatgagatgcaagcaggttacccaagaggcatccataccctgggc
cttccttcaacagtcaggaaaatagatgcagccttttctgacaaggaaaagaagaaaacg
tacttctttgcagaggacaaatactggagatttgatgagaagagacaatccatggagcca
ggttttcccaagcaaatagtggaagattttccaggggttgaaccagaggtggatgctgtt
tttaaagtatttgggttttactatttcttcagtggatcttcgcagtttgaatttgaccca
aatgcaaagaaagtgacacatgtgttgaagagtaacagctggttgaattgttag

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