Ovis aries (sheep): 100294652
Help
Entry
100294652 CDS
T03117
Gene name
AKT1
Definition
(RefSeq) RAC-alpha serine/threonine-protein kinase
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
oas
Ovis aries (sheep)
Pathway
oas01521
EGFR tyrosine kinase inhibitor resistance
oas01522
Endocrine resistance
oas01524
Platinum drug resistance
oas04010
MAPK signaling pathway
oas04012
ErbB signaling pathway
oas04014
Ras signaling pathway
oas04015
Rap1 signaling pathway
oas04022
cGMP-PKG signaling pathway
oas04024
cAMP signaling pathway
oas04062
Chemokine signaling pathway
oas04066
HIF-1 signaling pathway
oas04068
FoxO signaling pathway
oas04071
Sphingolipid signaling pathway
oas04072
Phospholipase D signaling pathway
oas04140
Autophagy - animal
oas04150
mTOR signaling pathway
oas04151
PI3K-Akt signaling pathway
oas04152
AMPK signaling pathway
oas04210
Apoptosis
oas04211
Longevity regulating pathway
oas04213
Longevity regulating pathway - multiple species
oas04218
Cellular senescence
oas04261
Adrenergic signaling in cardiomyocytes
oas04370
VEGF signaling pathway
oas04371
Apelin signaling pathway
oas04380
Osteoclast differentiation
oas04510
Focal adhesion
oas04550
Signaling pathways regulating pluripotency of stem cells
oas04611
Platelet activation
oas04613
Neutrophil extracellular trap formation
oas04620
Toll-like receptor signaling pathway
oas04625
C-type lectin receptor signaling pathway
oas04630
JAK-STAT signaling pathway
oas04660
T cell receptor signaling pathway
oas04662
B cell receptor signaling pathway
oas04664
Fc epsilon RI signaling pathway
oas04666
Fc gamma R-mediated phagocytosis
oas04668
TNF signaling pathway
oas04722
Neurotrophin signaling pathway
oas04725
Cholinergic synapse
oas04728
Dopaminergic synapse
oas04910
Insulin signaling pathway
oas04914
Progesterone-mediated oocyte maturation
oas04915
Estrogen signaling pathway
oas04917
Prolactin signaling pathway
oas04919
Thyroid hormone signaling pathway
oas04920
Adipocytokine signaling pathway
oas04922
Glucagon signaling pathway
oas04923
Regulation of lipolysis in adipocytes
oas04926
Relaxin signaling pathway
oas04929
GnRH secretion
oas04931
Insulin resistance
oas04932
Non-alcoholic fatty liver disease
oas04933
AGE-RAGE signaling pathway in diabetic complications
oas04935
Growth hormone synthesis, secretion and action
oas04973
Carbohydrate digestion and absorption
oas05010
Alzheimer disease
oas05017
Spinocerebellar ataxia
oas05132
Salmonella infection
oas05135
Yersinia infection
oas05142
Chagas disease
oas05145
Toxoplasmosis
oas05152
Tuberculosis
oas05160
Hepatitis C
oas05161
Hepatitis B
oas05162
Measles
oas05163
Human cytomegalovirus infection
oas05164
Influenza A
oas05165
Human papillomavirus infection
oas05166
Human T-cell leukemia virus 1 infection
oas05167
Kaposi sarcoma-associated herpesvirus infection
oas05168
Herpes simplex virus 1 infection
oas05169
Epstein-Barr virus infection
oas05170
Human immunodeficiency virus 1 infection
oas05200
Pathways in cancer
oas05205
Proteoglycans in cancer
oas05210
Colorectal cancer
oas05211
Renal cell carcinoma
oas05212
Pancreatic cancer
oas05213
Endometrial cancer
oas05214
Glioma
oas05215
Prostate cancer
oas05218
Melanoma
oas05220
Chronic myeloid leukemia
oas05221
Acute myeloid leukemia
oas05222
Small cell lung cancer
oas05223
Non-small cell lung cancer
oas05224
Breast cancer
oas05225
Hepatocellular carcinoma
oas05226
Gastric cancer
oas05230
Central carbon metabolism in cancer
oas05231
Choline metabolism in cancer
oas05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
oas05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100294652 (AKT1)
04012 ErbB signaling pathway
100294652 (AKT1)
04014 Ras signaling pathway
100294652 (AKT1)
04015 Rap1 signaling pathway
100294652 (AKT1)
04370 VEGF signaling pathway
100294652 (AKT1)
04371 Apelin signaling pathway
100294652 (AKT1)
04630 JAK-STAT signaling pathway
100294652 (AKT1)
04668 TNF signaling pathway
100294652 (AKT1)
04066 HIF-1 signaling pathway
100294652 (AKT1)
04068 FoxO signaling pathway
100294652 (AKT1)
04072 Phospholipase D signaling pathway
100294652 (AKT1)
04071 Sphingolipid signaling pathway
100294652 (AKT1)
04024 cAMP signaling pathway
100294652 (AKT1)
04022 cGMP-PKG signaling pathway
100294652 (AKT1)
04151 PI3K-Akt signaling pathway
100294652 (AKT1)
04152 AMPK signaling pathway
100294652 (AKT1)
04150 mTOR signaling pathway
100294652 (AKT1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100294652 (AKT1)
09143 Cell growth and death
04210 Apoptosis
100294652 (AKT1)
04218 Cellular senescence
100294652 (AKT1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100294652 (AKT1)
04550 Signaling pathways regulating pluripotency of stem cells
100294652 (AKT1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100294652 (AKT1)
04613 Neutrophil extracellular trap formation
100294652 (AKT1)
04620 Toll-like receptor signaling pathway
100294652 (AKT1)
04625 C-type lectin receptor signaling pathway
100294652 (AKT1)
04660 T cell receptor signaling pathway
100294652 (AKT1)
04662 B cell receptor signaling pathway
100294652 (AKT1)
04664 Fc epsilon RI signaling pathway
100294652 (AKT1)
04666 Fc gamma R-mediated phagocytosis
100294652 (AKT1)
04062 Chemokine signaling pathway
100294652 (AKT1)
09152 Endocrine system
04910 Insulin signaling pathway
100294652 (AKT1)
04922 Glucagon signaling pathway
100294652 (AKT1)
04923 Regulation of lipolysis in adipocytes
100294652 (AKT1)
04920 Adipocytokine signaling pathway
100294652 (AKT1)
04929 GnRH secretion
100294652 (AKT1)
04915 Estrogen signaling pathway
100294652 (AKT1)
04914 Progesterone-mediated oocyte maturation
100294652 (AKT1)
04917 Prolactin signaling pathway
100294652 (AKT1)
04926 Relaxin signaling pathway
100294652 (AKT1)
04935 Growth hormone synthesis, secretion and action
100294652 (AKT1)
04919 Thyroid hormone signaling pathway
100294652 (AKT1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
100294652 (AKT1)
09154 Digestive system
04973 Carbohydrate digestion and absorption
100294652 (AKT1)
09156 Nervous system
04725 Cholinergic synapse
100294652 (AKT1)
04728 Dopaminergic synapse
100294652 (AKT1)
04722 Neurotrophin signaling pathway
100294652 (AKT1)
09158 Development and regeneration
04380 Osteoclast differentiation
100294652 (AKT1)
09149 Aging
04211 Longevity regulating pathway
100294652 (AKT1)
04213 Longevity regulating pathway - multiple species
100294652 (AKT1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100294652 (AKT1)
05205 Proteoglycans in cancer
100294652 (AKT1)
05230 Central carbon metabolism in cancer
100294652 (AKT1)
05231 Choline metabolism in cancer
100294652 (AKT1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100294652 (AKT1)
09162 Cancer: specific types
05210 Colorectal cancer
100294652 (AKT1)
05212 Pancreatic cancer
100294652 (AKT1)
05225 Hepatocellular carcinoma
100294652 (AKT1)
05226 Gastric cancer
100294652 (AKT1)
05214 Glioma
100294652 (AKT1)
05221 Acute myeloid leukemia
100294652 (AKT1)
05220 Chronic myeloid leukemia
100294652 (AKT1)
05218 Melanoma
100294652 (AKT1)
05211 Renal cell carcinoma
100294652 (AKT1)
05215 Prostate cancer
100294652 (AKT1)
05213 Endometrial cancer
100294652 (AKT1)
05224 Breast cancer
100294652 (AKT1)
05222 Small cell lung cancer
100294652 (AKT1)
05223 Non-small cell lung cancer
100294652 (AKT1)
09164 Neurodegenerative disease
05010 Alzheimer disease
100294652 (AKT1)
05017 Spinocerebellar ataxia
100294652 (AKT1)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
100294652 (AKT1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100294652 (AKT1)
04931 Insulin resistance
100294652 (AKT1)
04933 AGE-RAGE signaling pathway in diabetic complications
100294652 (AKT1)
09171 Infectious disease: bacterial
05132 Salmonella infection
100294652 (AKT1)
05135 Yersinia infection
100294652 (AKT1)
05152 Tuberculosis
100294652 (AKT1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100294652 (AKT1)
05170 Human immunodeficiency virus 1 infection
100294652 (AKT1)
05161 Hepatitis B
100294652 (AKT1)
05160 Hepatitis C
100294652 (AKT1)
05164 Influenza A
100294652 (AKT1)
05162 Measles
100294652 (AKT1)
05168 Herpes simplex virus 1 infection
100294652 (AKT1)
05163 Human cytomegalovirus infection
100294652 (AKT1)
05167 Kaposi sarcoma-associated herpesvirus infection
100294652 (AKT1)
05169 Epstein-Barr virus infection
100294652 (AKT1)
05165 Human papillomavirus infection
100294652 (AKT1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100294652 (AKT1)
05142 Chagas disease
100294652 (AKT1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100294652 (AKT1)
01524 Platinum drug resistance
100294652 (AKT1)
01522 Endocrine resistance
100294652 (AKT1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oas01001
]
100294652 (AKT1)
Enzymes [BR:
oas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100294652 (AKT1)
Protein kinases [BR:
oas01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
100294652 (AKT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Pkinase_C
Kinase-like
PH_11
Seadorna_VP7
Pkinase_fungal
APH
Motif
Other DBs
NCBI-GeneID:
100294652
NCBI-ProteinID:
NP_001155329
UniProt:
A0A6P9FQK7
C5IJA6
LinkDB
All DBs
Position
18
AA seq
480 aa
AA seq
DB search
MNDVAVVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDLEQRESPLNNFSVAQC
QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKRQEEETMDF
RSGSPGENSGAEEMEVSLARPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
RERVFPEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
ILMEEIRFPRTLSPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFSSIVWQDVYEKK
LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDGMEGEDSERRPHFPQFSYSASGTA
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
atgaacgacgtggccgtcgtgaaggagggctggctgcacaagcgaggggagtacatcaag
acctggcggccccgttacttcctcctgaagaatgatggcaccttcatcggctacaaggag
cggccgcaggacctggagcagcgcgagtcgcccctcaacaacttctctgtggcccaatgc
cagctgatgaagacggagcggccgcggcccaacaccttcatcatccgctgcctgcagtgg
accacggtcatcgagcgcacgttccacgtggagacgcccgaggagcgggaggagtggacc
accgccatccagacggtggccgatggtctcaagaggcaggaggaggagacgatggacttc
cggtcgggctcacccggcgagaactcgggggccgaggagatggaggtgtcgctggccagg
cccaagcaccgcgtgaccatgaatgagtttgagtacctgaagctgctgggcaaaggcacc
ttcgggaaggtgatcctggtgaaggagaaggccacaggccgctactacgccatgaagatc
ctcaagaaggaggtcatcgtggccaaagacgaggtggcccacacgctcacagagaaccgc
gttctccagaactcccggcacccgttcctgacggccctgaagtactccttccagacgcac
gaccgcctgtgcttcgtcatggagtacgccaacgggggcgagctcttcttccacctgtcc
cgggagcgggtgtttcccgaggaccgggcccgcttctacggcgccgagatcgtgtcggcc
ctggattacctgcactcggagaagaacgtggtgtacagggacctcaagctcgagaacctc
atgctggacaaggacgggcacatcaagatcaccgactttggactgtgcaaggagggcatc
aaggacggcgccaccatgaagactttctgcgggacccccgagtacctggcccccgaggtg
ctggaagacaacgactacggccgggcggtggactggtgggggctgggcgtggtcatgtac
gagatgatgtgcggccgcctgcccttctacaaccaggaccacgagaagcttttcgagctc
atcctcatggaggagatccgcttcccgcgcacactcagcccggaggccaagtccttgctc
tcggggctgctcaagaaggaccccaagcagcggcttggtgggggctctgaggacgccaag
gagatcatgcagcaccgattcttcagcagcatcgtgtggcaggacgtgtacgagaagaag
ctcagcccgcccttcaagcctcaggtcacgtctgagacggacaccaggtattttgatgag
gagttcacagcccagatgatcaccattacgccacctgaccaagacgacggcatggagggg
gaggacagcgagcggaggccgcacttcccccagttttcctactcggccagcggcacggcc
tga
Ovis aries (sheep): 101118462
Help
Entry
101118462 CDS
T03117
Gene name
AKT3
Definition
(RefSeq) RAC-gamma serine/threonine-protein kinase
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
oas
Ovis aries (sheep)
Pathway
oas01521
EGFR tyrosine kinase inhibitor resistance
oas01522
Endocrine resistance
oas01524
Platinum drug resistance
oas04010
MAPK signaling pathway
oas04012
ErbB signaling pathway
oas04014
Ras signaling pathway
oas04015
Rap1 signaling pathway
oas04022
cGMP-PKG signaling pathway
oas04024
cAMP signaling pathway
oas04062
Chemokine signaling pathway
oas04066
HIF-1 signaling pathway
oas04068
FoxO signaling pathway
oas04071
Sphingolipid signaling pathway
oas04072
Phospholipase D signaling pathway
oas04140
Autophagy - animal
oas04150
mTOR signaling pathway
oas04151
PI3K-Akt signaling pathway
oas04152
AMPK signaling pathway
oas04210
Apoptosis
oas04211
Longevity regulating pathway
oas04213
Longevity regulating pathway - multiple species
oas04218
Cellular senescence
oas04261
Adrenergic signaling in cardiomyocytes
oas04370
VEGF signaling pathway
oas04371
Apelin signaling pathway
oas04380
Osteoclast differentiation
oas04510
Focal adhesion
oas04550
Signaling pathways regulating pluripotency of stem cells
oas04611
Platelet activation
oas04613
Neutrophil extracellular trap formation
oas04620
Toll-like receptor signaling pathway
oas04625
C-type lectin receptor signaling pathway
oas04630
JAK-STAT signaling pathway
oas04660
T cell receptor signaling pathway
oas04662
B cell receptor signaling pathway
oas04664
Fc epsilon RI signaling pathway
oas04666
Fc gamma R-mediated phagocytosis
oas04668
TNF signaling pathway
oas04722
Neurotrophin signaling pathway
oas04725
Cholinergic synapse
oas04728
Dopaminergic synapse
oas04910
Insulin signaling pathway
oas04914
Progesterone-mediated oocyte maturation
oas04915
Estrogen signaling pathway
oas04917
Prolactin signaling pathway
oas04919
Thyroid hormone signaling pathway
oas04920
Adipocytokine signaling pathway
oas04922
Glucagon signaling pathway
oas04923
Regulation of lipolysis in adipocytes
oas04926
Relaxin signaling pathway
oas04929
GnRH secretion
oas04931
Insulin resistance
oas04932
Non-alcoholic fatty liver disease
oas04933
AGE-RAGE signaling pathway in diabetic complications
oas04935
Growth hormone synthesis, secretion and action
oas04973
Carbohydrate digestion and absorption
oas05010
Alzheimer disease
oas05017
Spinocerebellar ataxia
oas05132
Salmonella infection
oas05135
Yersinia infection
oas05142
Chagas disease
oas05145
Toxoplasmosis
oas05152
Tuberculosis
oas05160
Hepatitis C
oas05161
Hepatitis B
oas05162
Measles
oas05163
Human cytomegalovirus infection
oas05164
Influenza A
oas05165
Human papillomavirus infection
oas05166
Human T-cell leukemia virus 1 infection
oas05167
Kaposi sarcoma-associated herpesvirus infection
oas05168
Herpes simplex virus 1 infection
oas05169
Epstein-Barr virus infection
oas05170
Human immunodeficiency virus 1 infection
oas05200
Pathways in cancer
oas05205
Proteoglycans in cancer
oas05210
Colorectal cancer
oas05211
Renal cell carcinoma
oas05212
Pancreatic cancer
oas05213
Endometrial cancer
oas05214
Glioma
oas05215
Prostate cancer
oas05218
Melanoma
oas05220
Chronic myeloid leukemia
oas05221
Acute myeloid leukemia
oas05222
Small cell lung cancer
oas05223
Non-small cell lung cancer
oas05224
Breast cancer
oas05225
Hepatocellular carcinoma
oas05226
Gastric cancer
oas05230
Central carbon metabolism in cancer
oas05231
Choline metabolism in cancer
oas05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
oas05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101118462 (AKT3)
04012 ErbB signaling pathway
101118462 (AKT3)
04014 Ras signaling pathway
101118462 (AKT3)
04015 Rap1 signaling pathway
101118462 (AKT3)
04370 VEGF signaling pathway
101118462 (AKT3)
04371 Apelin signaling pathway
101118462 (AKT3)
04630 JAK-STAT signaling pathway
101118462 (AKT3)
04668 TNF signaling pathway
101118462 (AKT3)
04066 HIF-1 signaling pathway
101118462 (AKT3)
04068 FoxO signaling pathway
101118462 (AKT3)
04072 Phospholipase D signaling pathway
101118462 (AKT3)
04071 Sphingolipid signaling pathway
101118462 (AKT3)
04024 cAMP signaling pathway
101118462 (AKT3)
04022 cGMP-PKG signaling pathway
101118462 (AKT3)
04151 PI3K-Akt signaling pathway
101118462 (AKT3)
04152 AMPK signaling pathway
101118462 (AKT3)
04150 mTOR signaling pathway
101118462 (AKT3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101118462 (AKT3)
09143 Cell growth and death
04210 Apoptosis
101118462 (AKT3)
04218 Cellular senescence
101118462 (AKT3)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101118462 (AKT3)
04550 Signaling pathways regulating pluripotency of stem cells
101118462 (AKT3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101118462 (AKT3)
04613 Neutrophil extracellular trap formation
101118462 (AKT3)
04620 Toll-like receptor signaling pathway
101118462 (AKT3)
04625 C-type lectin receptor signaling pathway
101118462 (AKT3)
04660 T cell receptor signaling pathway
101118462 (AKT3)
04662 B cell receptor signaling pathway
101118462 (AKT3)
04664 Fc epsilon RI signaling pathway
101118462 (AKT3)
04666 Fc gamma R-mediated phagocytosis
101118462 (AKT3)
04062 Chemokine signaling pathway
101118462 (AKT3)
09152 Endocrine system
04910 Insulin signaling pathway
101118462 (AKT3)
04922 Glucagon signaling pathway
101118462 (AKT3)
04923 Regulation of lipolysis in adipocytes
101118462 (AKT3)
04920 Adipocytokine signaling pathway
101118462 (AKT3)
04929 GnRH secretion
101118462 (AKT3)
04915 Estrogen signaling pathway
101118462 (AKT3)
04914 Progesterone-mediated oocyte maturation
101118462 (AKT3)
04917 Prolactin signaling pathway
101118462 (AKT3)
04926 Relaxin signaling pathway
101118462 (AKT3)
04935 Growth hormone synthesis, secretion and action
101118462 (AKT3)
04919 Thyroid hormone signaling pathway
101118462 (AKT3)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
101118462 (AKT3)
09154 Digestive system
04973 Carbohydrate digestion and absorption
101118462 (AKT3)
09156 Nervous system
04725 Cholinergic synapse
101118462 (AKT3)
04728 Dopaminergic synapse
101118462 (AKT3)
04722 Neurotrophin signaling pathway
101118462 (AKT3)
09158 Development and regeneration
04380 Osteoclast differentiation
101118462 (AKT3)
09149 Aging
04211 Longevity regulating pathway
101118462 (AKT3)
04213 Longevity regulating pathway - multiple species
101118462 (AKT3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101118462 (AKT3)
05205 Proteoglycans in cancer
101118462 (AKT3)
05230 Central carbon metabolism in cancer
101118462 (AKT3)
05231 Choline metabolism in cancer
101118462 (AKT3)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101118462 (AKT3)
09162 Cancer: specific types
05210 Colorectal cancer
101118462 (AKT3)
05212 Pancreatic cancer
101118462 (AKT3)
05225 Hepatocellular carcinoma
101118462 (AKT3)
05226 Gastric cancer
101118462 (AKT3)
05214 Glioma
101118462 (AKT3)
05221 Acute myeloid leukemia
101118462 (AKT3)
05220 Chronic myeloid leukemia
101118462 (AKT3)
05218 Melanoma
101118462 (AKT3)
05211 Renal cell carcinoma
101118462 (AKT3)
05215 Prostate cancer
101118462 (AKT3)
05213 Endometrial cancer
101118462 (AKT3)
05224 Breast cancer
101118462 (AKT3)
05222 Small cell lung cancer
101118462 (AKT3)
05223 Non-small cell lung cancer
101118462 (AKT3)
09164 Neurodegenerative disease
05010 Alzheimer disease
101118462 (AKT3)
05017 Spinocerebellar ataxia
101118462 (AKT3)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
101118462 (AKT3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101118462 (AKT3)
04931 Insulin resistance
101118462 (AKT3)
04933 AGE-RAGE signaling pathway in diabetic complications
101118462 (AKT3)
09171 Infectious disease: bacterial
05132 Salmonella infection
101118462 (AKT3)
05135 Yersinia infection
101118462 (AKT3)
05152 Tuberculosis
101118462 (AKT3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
101118462 (AKT3)
05170 Human immunodeficiency virus 1 infection
101118462 (AKT3)
05161 Hepatitis B
101118462 (AKT3)
05160 Hepatitis C
101118462 (AKT3)
05164 Influenza A
101118462 (AKT3)
05162 Measles
101118462 (AKT3)
05168 Herpes simplex virus 1 infection
101118462 (AKT3)
05163 Human cytomegalovirus infection
101118462 (AKT3)
05167 Kaposi sarcoma-associated herpesvirus infection
101118462 (AKT3)
05169 Epstein-Barr virus infection
101118462 (AKT3)
05165 Human papillomavirus infection
101118462 (AKT3)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
101118462 (AKT3)
05142 Chagas disease
101118462 (AKT3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101118462 (AKT3)
01524 Platinum drug resistance
101118462 (AKT3)
01522 Endocrine resistance
101118462 (AKT3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oas01001
]
101118462 (AKT3)
Enzymes [BR:
oas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101118462 (AKT3)
Protein kinases [BR:
oas01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
101118462 (AKT3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Pkinase_C
Kinase-like
FTA2
Motif
Other DBs
NCBI-GeneID:
101118462
NCBI-ProteinID:
XP_027831384
Ensembl:
ENSOARG00000006076
UniProt:
A0A6P7ELW9
LinkDB
All DBs
Position
12
AA seq
479 aa
AA seq
DB search
MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKXQ
LXKTEXPKPNTFIIRCLQWTTVIERTFHVDTPEEREEXTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atgagcgatgttaccattgtgaaagaaggttgggttcagaagaggggagaatatataaaa
aactggaggccaagatatttccttttgaagacagatggctcattcataggatataaagag
aaaccccaagatgtggatttaccttatcccctcaacaacttttcagtagcaaaangccag
ttaangaaaacagaangaccaaagccaaacacatttattatcagatgtctccagtggacc
actgtcatagagagaacatttcacgtagatactccagaggaaagggaagaanggacagaa
gctatccaggctgtagcagacagactccagaggcaagaagaagagagaatgaattgtagt
ccaacttcacaaattgataatataggagaggaagagatggatgcttctacaacccatcat
aagagaaagacaatgaatgattttgactatttgaaactactaggtaaaggcacttttggg
aaagttattttggttcgagagaaggcaagtggaaaatattatgctatgaagattctgaag
aaagaagttattattgccaaggatgaagtggcacacactttaactgaaagcagagtatta
aagaacactagacatccctttttaacatccctgaaatattccttccagacaaaagaccgt
ttgtgttttgtgatggaatatgttaatgggggagagctgtttttccatttgtcgagagag
cgggtgttctccgaggaccgcacacgtttctatggtgcagaaattgtctctgccttggac
tatctacattctggaaagattgtgtaccgtgatctcaagttggagaatttgatgctggat
aaagatggccacataaaaatcacagattttggactttgcaaagaagggatcactgatgca
gccaccatgaagactttctgtggtacaccagagtatctggcaccagaggtgttagaagat
aatgactatggccgagctgtggattggtggggccttggggttgtcatgtatgaaatgatg
tgtgggagattacctttctataaccaggatcatgagaaactttttgaactaattctaatg
gaagatattaaatttcctcgaacactctcttcagatgcaaaatcattgctttcagggctc
ttgataaaggatccaaataaacgccttggtggaggaccagatgatgcaaaagaaattatg
agacacagtttcttttctggagtaaactggcaagatgtgtatgataaaaagcttgtacct
ccttttaagcctcaagtaacatctgagacagacaccagatattttgatgaagaatttaca
gctcagactattacaataacaccacctgaaaaatatgatgaggacggtatggactgcatg
gacaatgagaggcggccgcacttccctcaattttcctactctgcaagtggacgagaataa
Ovis aries (sheep): 101119242
Help
Entry
101119242 CDS
T03117
Gene name
AKT2
Definition
(RefSeq) RAC-beta serine/threonine-protein kinase
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
oas
Ovis aries (sheep)
Pathway
oas01521
EGFR tyrosine kinase inhibitor resistance
oas01522
Endocrine resistance
oas01524
Platinum drug resistance
oas04010
MAPK signaling pathway
oas04012
ErbB signaling pathway
oas04014
Ras signaling pathway
oas04015
Rap1 signaling pathway
oas04022
cGMP-PKG signaling pathway
oas04024
cAMP signaling pathway
oas04062
Chemokine signaling pathway
oas04066
HIF-1 signaling pathway
oas04068
FoxO signaling pathway
oas04071
Sphingolipid signaling pathway
oas04072
Phospholipase D signaling pathway
oas04140
Autophagy - animal
oas04150
mTOR signaling pathway
oas04151
PI3K-Akt signaling pathway
oas04152
AMPK signaling pathway
oas04210
Apoptosis
oas04211
Longevity regulating pathway
oas04213
Longevity regulating pathway - multiple species
oas04218
Cellular senescence
oas04261
Adrenergic signaling in cardiomyocytes
oas04370
VEGF signaling pathway
oas04371
Apelin signaling pathway
oas04380
Osteoclast differentiation
oas04510
Focal adhesion
oas04550
Signaling pathways regulating pluripotency of stem cells
oas04611
Platelet activation
oas04613
Neutrophil extracellular trap formation
oas04620
Toll-like receptor signaling pathway
oas04625
C-type lectin receptor signaling pathway
oas04630
JAK-STAT signaling pathway
oas04660
T cell receptor signaling pathway
oas04662
B cell receptor signaling pathway
oas04664
Fc epsilon RI signaling pathway
oas04666
Fc gamma R-mediated phagocytosis
oas04668
TNF signaling pathway
oas04722
Neurotrophin signaling pathway
oas04725
Cholinergic synapse
oas04728
Dopaminergic synapse
oas04910
Insulin signaling pathway
oas04914
Progesterone-mediated oocyte maturation
oas04915
Estrogen signaling pathway
oas04917
Prolactin signaling pathway
oas04919
Thyroid hormone signaling pathway
oas04920
Adipocytokine signaling pathway
oas04922
Glucagon signaling pathway
oas04923
Regulation of lipolysis in adipocytes
oas04926
Relaxin signaling pathway
oas04929
GnRH secretion
oas04931
Insulin resistance
oas04932
Non-alcoholic fatty liver disease
oas04933
AGE-RAGE signaling pathway in diabetic complications
oas04935
Growth hormone synthesis, secretion and action
oas04973
Carbohydrate digestion and absorption
oas05010
Alzheimer disease
oas05017
Spinocerebellar ataxia
oas05132
Salmonella infection
oas05135
Yersinia infection
oas05142
Chagas disease
oas05145
Toxoplasmosis
oas05152
Tuberculosis
oas05160
Hepatitis C
oas05161
Hepatitis B
oas05162
Measles
oas05163
Human cytomegalovirus infection
oas05164
Influenza A
oas05165
Human papillomavirus infection
oas05166
Human T-cell leukemia virus 1 infection
oas05167
Kaposi sarcoma-associated herpesvirus infection
oas05168
Herpes simplex virus 1 infection
oas05169
Epstein-Barr virus infection
oas05170
Human immunodeficiency virus 1 infection
oas05200
Pathways in cancer
oas05205
Proteoglycans in cancer
oas05210
Colorectal cancer
oas05211
Renal cell carcinoma
oas05212
Pancreatic cancer
oas05213
Endometrial cancer
oas05214
Glioma
oas05215
Prostate cancer
oas05218
Melanoma
oas05220
Chronic myeloid leukemia
oas05221
Acute myeloid leukemia
oas05222
Small cell lung cancer
oas05223
Non-small cell lung cancer
oas05224
Breast cancer
oas05225
Hepatocellular carcinoma
oas05226
Gastric cancer
oas05230
Central carbon metabolism in cancer
oas05231
Choline metabolism in cancer
oas05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
oas05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101119242 (AKT2)
04012 ErbB signaling pathway
101119242 (AKT2)
04014 Ras signaling pathway
101119242 (AKT2)
04015 Rap1 signaling pathway
101119242 (AKT2)
04370 VEGF signaling pathway
101119242 (AKT2)
04371 Apelin signaling pathway
101119242 (AKT2)
04630 JAK-STAT signaling pathway
101119242 (AKT2)
04668 TNF signaling pathway
101119242 (AKT2)
04066 HIF-1 signaling pathway
101119242 (AKT2)
04068 FoxO signaling pathway
101119242 (AKT2)
04072 Phospholipase D signaling pathway
101119242 (AKT2)
04071 Sphingolipid signaling pathway
101119242 (AKT2)
04024 cAMP signaling pathway
101119242 (AKT2)
04022 cGMP-PKG signaling pathway
101119242 (AKT2)
04151 PI3K-Akt signaling pathway
101119242 (AKT2)
04152 AMPK signaling pathway
101119242 (AKT2)
04150 mTOR signaling pathway
101119242 (AKT2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101119242 (AKT2)
09143 Cell growth and death
04210 Apoptosis
101119242 (AKT2)
04218 Cellular senescence
101119242 (AKT2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101119242 (AKT2)
04550 Signaling pathways regulating pluripotency of stem cells
101119242 (AKT2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101119242 (AKT2)
04613 Neutrophil extracellular trap formation
101119242 (AKT2)
04620 Toll-like receptor signaling pathway
101119242 (AKT2)
04625 C-type lectin receptor signaling pathway
101119242 (AKT2)
04660 T cell receptor signaling pathway
101119242 (AKT2)
04662 B cell receptor signaling pathway
101119242 (AKT2)
04664 Fc epsilon RI signaling pathway
101119242 (AKT2)
04666 Fc gamma R-mediated phagocytosis
101119242 (AKT2)
04062 Chemokine signaling pathway
101119242 (AKT2)
09152 Endocrine system
04910 Insulin signaling pathway
101119242 (AKT2)
04922 Glucagon signaling pathway
101119242 (AKT2)
04923 Regulation of lipolysis in adipocytes
101119242 (AKT2)
04920 Adipocytokine signaling pathway
101119242 (AKT2)
04929 GnRH secretion
101119242 (AKT2)
04915 Estrogen signaling pathway
101119242 (AKT2)
04914 Progesterone-mediated oocyte maturation
101119242 (AKT2)
04917 Prolactin signaling pathway
101119242 (AKT2)
04926 Relaxin signaling pathway
101119242 (AKT2)
04935 Growth hormone synthesis, secretion and action
101119242 (AKT2)
04919 Thyroid hormone signaling pathway
101119242 (AKT2)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
101119242 (AKT2)
09154 Digestive system
04973 Carbohydrate digestion and absorption
101119242 (AKT2)
09156 Nervous system
04725 Cholinergic synapse
101119242 (AKT2)
04728 Dopaminergic synapse
101119242 (AKT2)
04722 Neurotrophin signaling pathway
101119242 (AKT2)
09158 Development and regeneration
04380 Osteoclast differentiation
101119242 (AKT2)
09149 Aging
04211 Longevity regulating pathway
101119242 (AKT2)
04213 Longevity regulating pathway - multiple species
101119242 (AKT2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101119242 (AKT2)
05205 Proteoglycans in cancer
101119242 (AKT2)
05230 Central carbon metabolism in cancer
101119242 (AKT2)
05231 Choline metabolism in cancer
101119242 (AKT2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101119242 (AKT2)
09162 Cancer: specific types
05210 Colorectal cancer
101119242 (AKT2)
05212 Pancreatic cancer
101119242 (AKT2)
05225 Hepatocellular carcinoma
101119242 (AKT2)
05226 Gastric cancer
101119242 (AKT2)
05214 Glioma
101119242 (AKT2)
05221 Acute myeloid leukemia
101119242 (AKT2)
05220 Chronic myeloid leukemia
101119242 (AKT2)
05218 Melanoma
101119242 (AKT2)
05211 Renal cell carcinoma
101119242 (AKT2)
05215 Prostate cancer
101119242 (AKT2)
05213 Endometrial cancer
101119242 (AKT2)
05224 Breast cancer
101119242 (AKT2)
05222 Small cell lung cancer
101119242 (AKT2)
05223 Non-small cell lung cancer
101119242 (AKT2)
09164 Neurodegenerative disease
05010 Alzheimer disease
101119242 (AKT2)
05017 Spinocerebellar ataxia
101119242 (AKT2)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
101119242 (AKT2)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101119242 (AKT2)
04931 Insulin resistance
101119242 (AKT2)
04933 AGE-RAGE signaling pathway in diabetic complications
101119242 (AKT2)
09171 Infectious disease: bacterial
05132 Salmonella infection
101119242 (AKT2)
05135 Yersinia infection
101119242 (AKT2)
05152 Tuberculosis
101119242 (AKT2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
101119242 (AKT2)
05170 Human immunodeficiency virus 1 infection
101119242 (AKT2)
05161 Hepatitis B
101119242 (AKT2)
05160 Hepatitis C
101119242 (AKT2)
05164 Influenza A
101119242 (AKT2)
05162 Measles
101119242 (AKT2)
05168 Herpes simplex virus 1 infection
101119242 (AKT2)
05163 Human cytomegalovirus infection
101119242 (AKT2)
05167 Kaposi sarcoma-associated herpesvirus infection
101119242 (AKT2)
05169 Epstein-Barr virus infection
101119242 (AKT2)
05165 Human papillomavirus infection
101119242 (AKT2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
101119242 (AKT2)
05142 Chagas disease
101119242 (AKT2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101119242 (AKT2)
01524 Platinum drug resistance
101119242 (AKT2)
01522 Endocrine resistance
101119242 (AKT2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oas01001
]
101119242 (AKT2)
Enzymes [BR:
oas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101119242 (AKT2)
Protein kinases [BR:
oas01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
101119242 (AKT2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Kinase-like
Pkinase_C
Motif
Other DBs
NCBI-GeneID:
101119242
NCBI-ProteinID:
XP_027834123
UniProt:
A0A6P7EV68
LinkDB
All DBs
Position
14
AA seq
481 aa
AA seq
DB search
MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC
QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRGPGADPM
DYKCGSPSDCSAAEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM
KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH
LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG
ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE
LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK
KLLPPFKPQVTSEVDTRYFDDEFTAQSITVTPPDRYDSLGSLELDQRAHFPQFSYSASIR
E
NT seq
1446 nt
NT seq
+upstream
nt +downstream
nt
atgaacgaggtgtctgtcatcaaagaaggctggctccataagcgcggtgaatatatcaag
acctggcggccccggtacttcctgctgaagagcgacggctccttcattggctataaggag
cggcctgaggcccccgaccagaccctgccccccttaaacaacttctctgtcgcagaatgc
cagctgatgaagaccgagagacctcggcccaataccttcgtcattcgctgtctgcagtgg
accacagtcatcgagaggaccttccatgttgactccccggacgagagggaggagtggatg
cgggccatccagatggttgccaacagcctcaagcagcggggcccaggggcggaccccatg
gactacaagtgtggctcccccagcgactgttctgcggccgaggagatggaggtggcggtt
agcaaggcgcgggccaaggtgaccatgaatgactttgactatctcaaactcctgggcaag
ggcacctttggcaaggtcatcctggtgcgggagaaggccactggccgctactatgccatg
aagatcctgcggaaggaggtgatcatcgccaaggatgaagtcgcccacacggtcaccgag
agccgcgtcctgcagaacaccaggcacccgttcctcactgcgctgaagtacgccttccag
acacacgaccgcctgtgcttcgtgatggagtacgccaacggtggcgagctgttcttccac
ttgtcgcgggagcgtgtcttcacagaggagcgggcccgcttttatggcgcagagatcgtc
tcagccctggagtacctgcactcgcgggacgtagtgtaccgcgacataaagctggaaaac
ctcatgctggacaaggacggccacatcaagatcaccgacttcggcctgtgcaaggagggc
atcagcgacggggccaccatgaagactttctgtgggacgcctgagtacctggcgcccgag
gtgctggaggacaacgactacggccgggcagtggactggtgggggctgggcgtggtcatg
tacgagatgatgtgtggccgcctgcccttctacaaccaggatcacgagcgcctcttcgag
ctcatcctcatggaggagatccgcttcccgcgcacgctcagccccgaggccaagtccctg
cttgctgggctgcttaagaaggaccctaagcagaggctcggcggagggcccagcgacgcc
aaggaggtcatggagcacaggttcttcctcagtatcaactggcaggacgtggtccagaag
aagctcctgccacccttcaagcctcaggtcacgtctgaggtcgacacaaggtactttgac
gacgagttcaccgcccagtccatcacagtcacgcccccggaccgctatgacagcctgggc
tcactggagctggaccagcgggcgcacttcccccagttctcctattcggccagcatccga
gagtga
DBGET
integrated database retrieval system
