KEGG   Ovis aries (sheep): 101116239Help
Entry
101116239         CDS       T03117                                 

Gene name
LIG4
Definition
(RefSeq) DNA ligase 4
  KO
K10777  DNA ligase 4 [EC:6.5.1.1]
Organism
oas  Ovis aries (sheep)
Pathway
oas03450  Non-homologous end-joining
Brite
KEGG Orthology (KO) [BR:oas00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03450 Non-homologous end-joining
    101116239 (LIG4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:oas03400]
    101116239 (LIG4)
Enzymes [BR:oas01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.1  DNA ligase (ATP)
     101116239 (LIG4)
DNA repair and recombination proteins [BR:oas03400]
 Eukaryotic Type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    DNA Ligase 4 complex
     101116239 (LIG4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DNA_ligase_A_M DNA_ligase_A_N DNA_ligase_A_C DNA_ligase_IV BRCT BRCT_2 RNA_ligase mRNA_cap_enzyme APG17
Motif
Other DBs
NCBI-GeneID: 101116239
NCBI-ProteinID: NP_001305004
UniProt: A0A0S2UQ43
LinkDB All DBs
Position
10
AA seq 911 aa AA seqDB search
MAASQTSQTVASHVPFADLCSTLERIQKSKGRAEKIRHFKAFLDSWRKFHDALHKNQKDV
TDSFYPAMRLILPQLERERMAYGIKEIMLAKLYVELLNLPRDGKDALKLLNYRTPTGTRG
DAGDFAMIAYFVLKPRCLQKGSLSIQQVNDILDSIASNNSAKRKDLMKKSVLQLITQSSA
LEQKWLIRMIVKDLKLGFSQHTVFSVFHRDAAELHNVTTDLEKVCRQLHDPSVGLSDISI
TLFSAFKPMLAAIADIERIEKDMKHQSFYIETKLDGERMQMHKDGDVYRYFSRNGYNYED
QFGASPQEGSLTPFIHNAFRTDVLNCILDGEMMAYNPNTQTFMQKGNKFDIKRMVEDSEL
QTCYCVFDVLMVNDKKLGHETLRKRFEILNSVFTPVPGRIEIVQKTQAHTKKEVIDALNE
AIDKREEGIMVKHPLSIYKPDKRGEGWLKIKPEYVSGLMDELDILIVGGYWGKGARGGMM
SHFLCAVAEKPASGEKPSVFHTLCRVGSGYTMKELYDLGLKLAKHWKAFHRKAPPSNILC
GTEKPEVYIEPCNSVIVQVKATEIVPSDMYKTGCTLRFPRIEKIREDKEWYECTSLEDLE
QLRGKACGKLASKHLYMSGDDEPQEKKRKAAPKMKKVIGIIEHLKAPNLSNVNRVSTVFE
DVEFCVMSGTSNHPKPDLENRIAELGGYVVQNPGPDTYCVIAGSDNIRVKNIISSDKHDV
VKPEWLLECFRTRSCVPWQPRFMIHMCPSTKQHFAQEYDQFGDSYFVDTDLHRLKEVFSG
IKNAGEQTPGEMSPVIADLEHRYSWASMPLSMFRHHTVYLDLYAVINDLSTRIKGARLAI
TALELRFHGAQVVSCLAEGVSHVIVGEDQSRVADLKAIRRTLKRKFKILQERWVTVSIDK
CELQEENQYLV
NT seq 2736 nt NT seq  +upstreamnt  +downstreamnt
atggctgcctcacaaacctcacagactgttgcatctcacgttccttttgcagatttatgt
tcgactttagaacgaatacagaaaagtaaagggcgtgcagaaaaaatcagacacttcaaa
gcatttttagattcttggagaaaatttcatgatgcccttcataagaaccaaaaagatgtc
acagattctttttatccagccatgagacttattcttcctcagctggaaagggagagaatg
gcctatggaatcaaagaaattatgctggctaagctttatgttgaattgcttaacttgcct
cgagatggaaaagatgcccttaagcttttgaactacagaacaccgaccggaacccgtgga
gatgctggagactttgcaatgattgcgtactttgtattgaaacccagatgtctacagaaa
ggaagcctaagcattcagcaagtaaatgacattttagactccattgccagcaataattct
gccaaaaggaaagacctaatgaagaaaagtgttcttcagcttataactcagagttcagca
cttgaacaaaaatggctgatacggatgattgttaaggacctcaagcttggctttagtcag
cacactgtattttctgtttttcaccgtgatgctgctgagttgcataatgtcaccacagat
ctggagaaggtctgtaggcaactgcacgatccttcagtgggactcagtgacatttccatc
accctattctctgcctttaaacccatgctggccgctatagcagatattgagcgaattgag
aaggacatgaaacaccagagtttctacatcgaaaccaagctcgacggcgagcggatgcag
atgcacaaggatggggatgtgtaccggtacttctctcgcaatgggtataactatgaggac
cagtttggtgcttccccacaggaagggtccctcacaccattcattcataatgcattcaga
acagatgtgctgaactgtatcctcgacggtgagatgatggcctacaaccctaacacacag
acttttatgcaaaaggggaataagtttgatattaaaagaatggtggaagattctgagctg
cagacttgttactgtgtttttgatgtattgatggttaatgataaaaagctaggacatgag
accctgagaaagaggtttgaaattcttaatagtgttttcacacctgtaccaggtagaata
gaaatagtgcagaaaacacaagctcatactaagaaagaagtaattgatgctttgaatgaa
gcgatagataaaagagaagaggggatcatggtaaaacacccgctgtccatttacaagcca
gataaaagaggtgaaggatggttaaaaattaaaccagagtatgtcagtggactgatggat
gagctggacatcttaatcgtcgggggctactggggaaagggtgcccggggcgggatgatg
tctcattttttgtgcgctgtggcagagaagcccgcttctggtgaaaaaccctcagtgttt
cacactctctgtcgcgttggctcgggttacactatgaaagaactgtatgacctgggtttg
aagttggcgaaacactggaaggcttttcataggaaagccccaccaagcaacattctatgt
ggaacagagaagccagaggtctacattgagccttgcaattcagtcattgttcaggttaag
gccacagagatcgtccccagtgacatgtataaaaccggctgcacgttgcgttttccacgg
attgagaaaataagagaagacaaagaatggtacgaatgtacatccctggaggacttagag
caacttcgagggaaggcctgtggaaagctcgcatccaaacacctttacatgagtggcgat
gatgaaccacaagagaaaaagcggaaagctgccccaaagatgaagaaagtcattggaatt
attgagcacctaaaagctcccaacctttctaacgtaaacagggtttctactgtctttgaa
gacgtggagttttgtgtcatgagtggaaccagcaaccatcccaagcctgacctggaaaac
agaatcgccgaattgggtggttacgtagtacagaacccaggcccagacacgtactgtgtg
atcgcagggtctgacaacattcgagtgaagaatatcatctcttcagataaacatgatgtc
gtcaagccagagtggctgctggagtgttttaggaccagaagctgtgtgccctggcaaccc
cgcttcatgatccacatgtgcccgtcgacaaagcaacactttgcccaggaatacgaccaa
ttcggggatagttactttgtcgacacagatttgcaccgactgaaggaagtgttttcggga
attaaaaacgctggtgagcagactcctggggagatgagtcctgtgattgctgatttggaa
cacaggtattcctgggccagcatgcctcttagcatgtttagacaccacaccgtttatttg
gacttgtacgctgtcatcaatgacttaagcaccagaatcaagggagctaggttagccatc
acagccttggagcttcgatttcatggagcacaagtagtttcctgtttagctgagggagtg
tctcacgtcattgttggggaagatcagagtcgggttgcagacttgaaagctattcgaagg
actcttaagaggaaatttaaaatcttacaagaacgttgggtcactgtttcaatagacaag
tgtgaattacaggaggaaaatcagtatttggtttga

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