Ovis aries (sheep): 780519
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Entry
780519 CDS
T03117
Gene name
ERBB2
Definition
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
oas
Ovis aries (sheep)
Pathway
oas01521
EGFR tyrosine kinase inhibitor resistance
oas01522
Endocrine resistance
oas01524
Platinum drug resistance
oas04010
MAPK signaling pathway
oas04012
ErbB signaling pathway
oas04020
Calcium signaling pathway
oas04066
HIF-1 signaling pathway
oas04151
PI3K-Akt signaling pathway
oas04510
Focal adhesion
oas04520
Adherens junction
oas04530
Tight junction
oas05200
Pathways in cancer
oas05205
Proteoglycans in cancer
oas05206
MicroRNAs in cancer
oas05212
Pancreatic cancer
oas05213
Endometrial cancer
oas05215
Prostate cancer
oas05219
Bladder cancer
oas05223
Non-small cell lung cancer
oas05224
Breast cancer
oas05226
Gastric cancer
oas05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
780519 (ERBB2)
04012 ErbB signaling pathway
780519 (ERBB2)
04066 HIF-1 signaling pathway
780519 (ERBB2)
04020 Calcium signaling pathway
780519 (ERBB2)
04151 PI3K-Akt signaling pathway
780519 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
780519 (ERBB2)
04520 Adherens junction
780519 (ERBB2)
04530 Tight junction
780519 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
780519 (ERBB2)
05206 MicroRNAs in cancer
780519 (ERBB2)
05205 Proteoglycans in cancer
780519 (ERBB2)
05230 Central carbon metabolism in cancer
780519 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
780519 (ERBB2)
05226 Gastric cancer
780519 (ERBB2)
05219 Bladder cancer
780519 (ERBB2)
05215 Prostate cancer
780519 (ERBB2)
05213 Endometrial cancer
780519 (ERBB2)
05224 Breast cancer
780519 (ERBB2)
05223 Non-small cell lung cancer
780519 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
780519 (ERBB2)
01524 Platinum drug resistance
780519 (ERBB2)
01522 Endocrine resistance
780519 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oas01001
]
780519 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
oas04147
]
780519 (ERBB2)
04090 CD molecules [BR:
oas04090
]
780519 (ERBB2)
Enzymes [BR:
oas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
780519 (ERBB2)
Protein kinases [BR:
oas01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
780519 (ERBB2)
Exosome [BR:
oas04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
780519 (ERBB2)
CD molecules [BR:
oas04090
]
Proteins
780519 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
APH
Kinase-like
Motif
Other DBs
NCBI-GeneID:
780519
NCBI-ProteinID:
XP_014954244
Ensembl:
ENSOARG00000011865
UniProt:
A0A6P3YL94
LinkDB
All DBs
Position
11
AA seq
1258 aa
AA seq
DB search
MELAAWCRWGLLLALLPPGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPADASLSFLQEIQEVQGYVLIAHNRVSQVPLQRLRIVRGTQLFEEHYALAVLDNG
DFLEGAAPAAGTASGGLQELQLRSLTEILKGGVLIQRNPQLCHQDTILWEDIFHKNNQLP
LKQIDTNRSRACAPCSPACKAPNCWGESSEDCQSLTRTVCASGCARCKGPQPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCAPVCYGLGMEHLREVRAVTSAN
IQEFAGCKKIFGSLAFLPESFAGDPDSNITPLQAEQLKVFESLEEITGYLYISAWPDSLP
DLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELSSGLALIHRNARLCFVHTV
PWDQLFQNPHQALLHSANRPENECVGEGLACYPLCAQGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLQGLPREYVKDRYCLPCHPECLPQNGSVTCFGSEADQCVACAHYKDPPFCV
ARCPSGVKPDLSFMPIWKFPDEEGICQPCPINCTHSCVDLDDKGCPAEQRASPVTSIIAA
VVGVLLVVLVGLVFGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKE
TELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGV
GSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLE
DVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRR
RFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVK
CWMIDSECRPRFRELVTEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDL
VDAEEYLVPQQGFFCPDPAPGAGGTAHRRHRSTSTRSGGGELTLGLEPSEEEPPRSPLAP
SEGAGSDVFDGDLGMGAAKGLQSLPQHDSSPLQRYSEDPTVPLSPEADGYVAPSTCSPQP
EYVNQPEVRPQPPSPLEGPLPPPRPAGSTLERPKTLSPGKNGVVKDVFAFGAAVENPEYL
APRGRAAPQSHPSPAFSPAFDNLYYWDQDPSERGTPSSSFEGTPTAENPEYLGLDMPV
NT seq
3777 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccccccggagcc
gcgggcacccaagtgtgcaccggcacagacatgaagctgcggctgccagccagtcccgag
acccacctggacatgctacgccacctctaccaaggctgtcaggtggtgcagggtaacctg
gagctcacctatctgcctgctgatgccagcctctccttcctgcaggaaatccaggaggtg
cagggctatgtgctcatcgctcacaatcgagtgagtcaggtcccactgcagagactgcga
atcgtgcgaggcactcagctctttgaggaacactacgccctggccgtgctggacaatgga
gactttctggaaggtgctgcccctgctgcgggcacggcctcaggagggctgcaggagctg
cagctgcgaagcctcacagagatcctcaagggaggggtcttgatccagcggaacccccag
ctctgccaccaggacacgattttgtgggaggatatcttccacaagaacaaccagctgccc
ctcaagcagatagacaccaaccgctcacgggcctgcgcaccctgttctccagcttgtaaa
gctcccaactgctggggagaaagttctgaggactgtcagagcttgacgcggaccgtctgt
gccagtggctgtgcccgctgtaagggcccacagcccaccgactgctgccacgagcagtgc
gctgccggctgtactggccccaagcactctgactgcctggcctgcctccacttcaaccac
agcggtatctgtgagctgcactgcccagctctggtcacctacaacacggacaccttcgag
tcgatgcccaaccccgaggggcgttataccttcggtgccagctgtgtgaccgcctgtcct
tacaactacctgtctacggatgtgggatcctgcaccctggtttgtcccctgaacaaccaa
gaggtgacagctgaggatggaacccagaggtgtgagaaatgcagcaagccctgtgcccca
gtgtgctacggtctgggcatggaacacctgcgggaggtgagggcagtcaccagtgccaac
atccaggagtttgccggctgcaagaagatttttgggagcctggcgtttctgccagagagc
tttgcaggggacccagactctaacatcaccccactgcaggctgagcagctcaaagtgttt
gagtctctggaggagatcacaggttacctgtacatctcagcgtggccagacagcctgcct
gacctcagcgtcttccagaacctgcgagtaatccggggacgagttctgcatgatggtgcc
tactcgctgacgctgcaagggctgggcatcagctggctggggctgcgctcgctgcgggaa
ctgagcagcgggctggccctcatccaccgcaacgcccgcctctgcttcgtacacacggtg
ccctgggaccagctcttccagaacccccaccaggctctgctccacagcgccaacaggcca
gagaatgagtgcgtgggtgagggcctggcctgctacccactgtgcgcccaagggcactgc
tggggtcccgggcccacccagtgcgtcaactgcagccagttccttcggggccaggaatgc
gtggaggaatgccgagtactacagggactacaggggcttccccgggagtacgtgaaggac
aggtactgtctgccgtgccaccccgagtgtcttccccagaatggctcagtgacctgcttt
ggctcggaggctgaccaatgtgtggcttgtgcccactacaaggatcctcccttctgcgtg
gctcgctgccccagtggtgtgaagcctgacctctccttcatgcccatctggaagtttcca
gatgaagagggcatatgccagccatgccccatcaactgcacccactcctgtgtggacttg
gatgacaagggctgtcccgccgagcagagagccagccctgtgacatccatcattgccgct
gtggtgggcgttctgctggttgtccttgtggggctggtgttcggcatcctcattaagcga
aggcggcagaagatccggaagtatacaatgcggcggctgctgcaggagacggagctggtg
gagcccctgacgcccagcggagcgatgcccaatcaggctcagatgcggatcttaaaagag
acagagctgaggaaagtgaaggtgctaggatctggagcttttggcaccgtctacaagggc
atctggatccccgatggggaaaatgtgaaaatccccgtggccatcaaggtgttgagggaa
aacacatctcccaaagccaacaaggaaatcttggacgaagcatatgtgatggctggtgta
ggctccccatatgtgtcccgcctcctgggcatctgcctgacatccacagtgcagctggtg
acacagcttatgccctatggctgcctcctcgaccacgtccgagaacaccgtgggcgcctg
ggctcccaggacctgctgaactggtgtgtgcagattgccaaggggatgagctacttggag
gatgtgcggctcgtgcatagggacctggctgcccggaacgtgctggtcaagagtcccaac
catgtgaagattacagacttcgggctagcgcgactgctagacattgacgagacagagtac
cacgcagatgggggcaaggtgcccatcaagtggatggcattggagtccattctccgccgg
cggttcacccaccagagtgacgtgtggagctatggtgtgactgtgtgggagctgatgact
tttggggccaaaccttatgatgggatcccagcccgggagattcctgacctgctggagaag
ggagaacggctgccccagccccccatctgcaccattgatgtctacatgatcatggtcaaa
tgttggatgattgactctgaatgtcggccgaggttccgggagttagtgactgaattctcc
cgcatggccagggacccccagcgctttgtggtcatccagaatgaagacttgggccctgct
agccccctggatagcaccttctaccgctcgctgctggaggatgacgacatgggagacctg
gtggatgcggaggagtacctggtaccccagcagggcttcttctgcccagaccctgcccca
ggagctggaggcacggcccaccgcaggcaccgcagcacatccaccaggagtggtggtggt
gagctgacactggggctggagccctctgaggaggagccccccagatctccgctggcacct
tccgaaggggcaggctctgatgtgtttgatggcgacttgggaatgggggcggccaagggg
ctgcagtccctcccccaacacgactctagccctctacagcggtacagcgaggaccccaca
gtacccctttctcccgaggctgatggctacgttgccccctcgacctgcagcccccagccc
gaatacgtgaaccagccagaggttcgcccacagcccccgtcacccctagagggtcctctg
ccgcctcctcgacctgcaggttccactctggaaaggcccaagacgctctcccctgggaag
aatggggttgtcaaagacgtttttgcctttggggctgccgtggagaaccccgagtacttg
gcaccccggggcagggccgcccctcagtcccacccttctccagccttcagcccagccttt
gacaacctctactactgggaccaggacccatcagagcggggcactccatccagctccttt
gaagggacccctacggcagagaaccctgagtacctgggcctggacatgccagtatga
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integrated database retrieval system
