KEGG   Oryctolagus cuniculus (rabbit): 100037719
Entry
100037719         CDS       T03373                                 

Gene name
PRKCB, PRKCB1
Definition
(RefSeq) protein kinase C beta
  KO
K19662  classical protein kinase C beta type [EC:2.7.11.13]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu01521  EGFR tyrosine kinase inhibitor resistance
ocu04010  MAPK signaling pathway
ocu04012  ErbB signaling pathway
ocu04014  Ras signaling pathway
ocu04015  Rap1 signaling pathway
ocu04020  Calcium signaling pathway
ocu04062  Chemokine signaling pathway
ocu04064  NF-kappa B signaling pathway
ocu04066  HIF-1 signaling pathway
ocu04070  Phosphatidylinositol signaling system
ocu04071  Sphingolipid signaling pathway
ocu04150  mTOR signaling pathway
ocu04270  Vascular smooth muscle contraction
ocu04310  Wnt signaling pathway
ocu04370  VEGF signaling pathway
ocu04510  Focal adhesion
ocu04540  Gap junction
ocu04650  Natural killer cell mediated cytotoxicity
ocu04662  B cell receptor signaling pathway
ocu04666  Fc gamma R-mediated phagocytosis
ocu04670  Leukocyte transendothelial migration
ocu04713  Circadian entrainment
ocu04720  Long-term potentiation
ocu04723  Retrograde endocannabinoid signaling
ocu04724  Glutamatergic synapse
ocu04725  Cholinergic synapse
ocu04726  Serotonergic synapse
ocu04727  GABAergic synapse
ocu04728  Dopaminergic synapse
ocu04730  Long-term depression
ocu04750  Inflammatory mediator regulation of TRP channels
ocu04911  Insulin secretion
ocu04912  GnRH signaling pathway
ocu04916  Melanogenesis
ocu04918  Thyroid hormone synthesis
ocu04919  Thyroid hormone signaling pathway
ocu04921  Oxytocin signaling pathway
ocu04925  Aldosterone synthesis and secretion
ocu04928  Parathyroid hormone synthesis, secretion and action
ocu04929  GnRH secretion
ocu04931  Insulin resistance
ocu04933  AGE-RAGE signaling pathway in diabetic complications
ocu04935  Growth hormone synthesis, secretion and action
ocu04960  Aldosterone-regulated sodium reabsorption
ocu04961  Endocrine and other factor-regulated calcium reabsorption
ocu04970  Salivary secretion
ocu04971  Gastric acid secretion
ocu04972  Pancreatic secretion
ocu04973  Carbohydrate digestion and absorption
ocu05017  Spinocerebellar ataxia
ocu05022  Pathways of neurodegeneration - multiple diseases
ocu05031  Amphetamine addiction
ocu05032  Morphine addiction
ocu05140  Leishmaniasis
ocu05143  African trypanosomiasis
ocu05146  Amoebiasis
ocu05161  Hepatitis B
ocu05163  Human cytomegalovirus infection
ocu05164  Influenza A
ocu05170  Human immunodeficiency virus 1 infection
ocu05200  Pathways in cancer
ocu05205  Proteoglycans in cancer
ocu05206  MicroRNAs in cancer
ocu05214  Glioma
ocu05223  Non-small cell lung cancer
ocu05225  Hepatocellular carcinoma
ocu05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100037719 (PRKCB)
   04012 ErbB signaling pathway
    100037719 (PRKCB)
   04014 Ras signaling pathway
    100037719 (PRKCB)
   04015 Rap1 signaling pathway
    100037719 (PRKCB)
   04310 Wnt signaling pathway
    100037719 (PRKCB)
   04370 VEGF signaling pathway
    100037719 (PRKCB)
   04064 NF-kappa B signaling pathway
    100037719 (PRKCB)
   04066 HIF-1 signaling pathway
    100037719 (PRKCB)
   04020 Calcium signaling pathway
    100037719 (PRKCB)
   04070 Phosphatidylinositol signaling system
    100037719 (PRKCB)
   04071 Sphingolipid signaling pathway
    100037719 (PRKCB)
   04150 mTOR signaling pathway
    100037719 (PRKCB)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100037719 (PRKCB)
   04540 Gap junction
    100037719 (PRKCB)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    100037719 (PRKCB)
   04662 B cell receptor signaling pathway
    100037719 (PRKCB)
   04666 Fc gamma R-mediated phagocytosis
    100037719 (PRKCB)
   04670 Leukocyte transendothelial migration
    100037719 (PRKCB)
   04062 Chemokine signaling pathway
    100037719 (PRKCB)
  09152 Endocrine system
   04911 Insulin secretion
    100037719 (PRKCB)
   04929 GnRH secretion
    100037719 (PRKCB)
   04912 GnRH signaling pathway
    100037719 (PRKCB)
   04921 Oxytocin signaling pathway
    100037719 (PRKCB)
   04935 Growth hormone synthesis, secretion and action
    100037719 (PRKCB)
   04918 Thyroid hormone synthesis
    100037719 (PRKCB)
   04919 Thyroid hormone signaling pathway
    100037719 (PRKCB)
   04928 Parathyroid hormone synthesis, secretion and action
    100037719 (PRKCB)
   04916 Melanogenesis
    100037719 (PRKCB)
   04925 Aldosterone synthesis and secretion
    100037719 (PRKCB)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    100037719 (PRKCB)
  09154 Digestive system
   04970 Salivary secretion
    100037719 (PRKCB)
   04971 Gastric acid secretion
    100037719 (PRKCB)
   04972 Pancreatic secretion
    100037719 (PRKCB)
   04973 Carbohydrate digestion and absorption
    100037719 (PRKCB)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100037719 (PRKCB)
   04961 Endocrine and other factor-regulated calcium reabsorption
    100037719 (PRKCB)
  09156 Nervous system
   04724 Glutamatergic synapse
    100037719 (PRKCB)
   04727 GABAergic synapse
    100037719 (PRKCB)
   04725 Cholinergic synapse
    100037719 (PRKCB)
   04728 Dopaminergic synapse
    100037719 (PRKCB)
   04726 Serotonergic synapse
    100037719 (PRKCB)
   04720 Long-term potentiation
    100037719 (PRKCB)
   04730 Long-term depression
    100037719 (PRKCB)
   04723 Retrograde endocannabinoid signaling
    100037719 (PRKCB)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100037719 (PRKCB)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100037719 (PRKCB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100037719 (PRKCB)
   05206 MicroRNAs in cancer
    100037719 (PRKCB)
   05205 Proteoglycans in cancer
    100037719 (PRKCB)
   05231 Choline metabolism in cancer
    100037719 (PRKCB)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100037719 (PRKCB)
   05214 Glioma
    100037719 (PRKCB)
   05223 Non-small cell lung cancer
    100037719 (PRKCB)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    100037719 (PRKCB)
   05022 Pathways of neurodegeneration - multiple diseases
    100037719 (PRKCB)
  09165 Substance dependence
   05031 Amphetamine addiction
    100037719 (PRKCB)
   05032 Morphine addiction
    100037719 (PRKCB)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100037719 (PRKCB)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100037719 (PRKCB)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100037719 (PRKCB)
   05164 Influenza A
    100037719 (PRKCB)
   05161 Hepatitis B
    100037719 (PRKCB)
   05163 Human cytomegalovirus infection
    100037719 (PRKCB)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100037719 (PRKCB)
   05140 Leishmaniasis
    100037719 (PRKCB)
   05143 African trypanosomiasis
    100037719 (PRKCB)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100037719 (PRKCB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ocu01001]
    100037719 (PRKCB)
Enzymes [BR:ocu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     100037719 (PRKCB)
Protein kinases [BR:ocu01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   100037719 (PRKCB)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C C1_2 Kinase-like CEP76-C2 APH
Other DBs
NCBI-GeneID: 100037719
NCBI-ProteinID: NP_001095195
Ensembl: ENSOCUG00000013916
UniProt: P05772
LinkDB
Position
6
AA seq 671 aa
MADPAAGQPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGS
LLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDREVLIVVVRDA
KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRL
SVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFNVPVPPEGSEGNEE
LRQKFERAKIGQGTKTPEEKTTNTISKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE
RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVM
EYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHI
KIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP
FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKDHAFF
RYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGF
SYTNPEFVINV
NT seq 2016 nt   +upstreamnt  +downstreamnt
atggctgacccggctgcggggcagccgccgagcgagggcgaggagagcaccgtgcgcttc
gcccgcaaaggcgccctccggcagaagaacgtgcacgaggtgaagaaccacaaattcacc
gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggggcttt
gggaagcagggattccagtgtcaagtttgctgctttgtagtgcacaagcggtgccatgag
tttgtcacattctcctgccctggtgctgacaagggcccagcctctgatgacccccggagc
aaacacaagttcaagatccacacgtactccagccccacgttctgtgaccactgtggatcc
ctgctgtacgggctcatccaccaggggatgaaatgcgacacctgcatgatgaacgtgcac
aagcgctgcgtgatgaacgtcccaagtctatgcggcaccgaccacaccgagcgccgtggc
cgcatctacatccaggcccacatcgaccgcgaggtcctcatcgtcgtcgtaagagatgct
aaaaaccttgtacctatggaccccaatggcttgtcagacccctacgtaaaactgaaactg
attcctgatcccaaaagcgagagcaagcagaagaccaaaactatcaagtgctccctcaac
cccgagtggaacgagacattcagatttcagctgaaagaatcggacaaagacagaagactt
tcagtagagatttgggactgggatctgaccagcaggaatgacttcatggggtctttgtcc
tttgggatttctgagctgcagaaagcaggtgttgatggctggtttaagttgctgagccag
gaggaaggcgagtacttcaacgtgcctgtgccgccagaggggagtgagggcaatgaagaa
ctgcggcagaaatttgagagagccaagatcggtcagggaaccaagaccccagaagaaaag
acgaccaacactatttccaaatttgacaacaatggcaacagggaccggatgaaactgacc
gatttcaacttcctgatggtgctggggaaaggcagtttcggcaaggtgatgctgtcggag
cggaagggcacagacgagctctacgctgtgaagatcctcaaaaaggacgtggtgatccaa
gatgacgacgtggaatgcaccatggtagagaagcgggtgctggccctgcctgggaagcca
ccgttcctcacccagctccactcctgcttccagaccatggaccgcctgtacttcgtcatg
gagtatgtgaacggaggggacctcatgtatcacatccaacaagttggccggttcaaggag
cctcatgctgtattttacgctgcagaaattgccatcggtctgttcttcctacagagcaag
ggcatcatttaccgtgacctgaaacttgacaatgtgatgctggattccgagggacacatc
aagatcgctgactttggcatgtgtaaggaaaacatttgggatggggtgacaaccaagacc
ttttgtggaactccagactacattgctccagagataattgcttatcagccctatgggaag
tccgtggattggtgggcattcggagtcctgctgtatgaaatgctggctggacaggcaccc
tttgaaggggaggatgaggacgagctcttccagtccatcatggaacacaacgtggcttac
cccaagtccatgtccaaggaagccgtggccatctgcaaagggctgatgaccaaacacccg
ggcaagcgtctgggttgtggacctgaaggtgaacgtgacatcaaagaccatgcgtttttc
cgatacattgattgggagaagcttgaacgcaaggagatacagcctccctacaagccaaaa
gccagggacaagcgagacacctccaacttcgacaaagagttcaccagacagcctgtggaa
ctgactcccactgataagctcttcatcatgaacttggaccaaaatgaatttgctggcttc
tcttatactaacccagagtttgtcattaatgtgtag

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