KEGG   Oryctolagus cuniculus (rabbit): 100345729
Entry
100345729         CDS       T03373                                 

Gene name
CHEK1
Definition
(RefSeq) checkpoint kinase 1
  KO
K02216  serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu04110  Cell cycle
ocu04115  p53 signaling pathway
ocu04218  Cellular senescence
ocu05166  Human T-cell leukemia virus 1 infection
ocu05170  Human immunodeficiency virus 1 infection
ocu05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    100345729 (CHEK1)
   04115 p53 signaling pathway
    100345729 (CHEK1)
   04218 Cellular senescence
    100345729 (CHEK1)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    100345729 (CHEK1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100345729 (CHEK1)
   05170 Human immunodeficiency virus 1 infection
    100345729 (CHEK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ocu01001]
    100345729 (CHEK1)
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:ocu03400]
    100345729 (CHEK1)
Enzymes [BR:ocu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     100345729 (CHEK1)
Protein kinases [BR:ocu01001]
 Serine/threonine kinases: CAMK group
  CAMKL family
   100345729 (CHEK1)
DNA repair and recombination proteins [BR:ocu03400]
 Eukaryotic type
  Check point factors
   Other check point factors
    100345729 (CHEK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Pkinase_fungal Kdo APH
Other DBs
NCBI-GeneID: 100345729
NCBI-ProteinID: XP_002708707
Ensembl: ENSOCUG00000014703
UniProt: G1T7Y1
LinkDB
Position
1
AA seq 476 aa
MAVPFVEDWDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRAIDCPENIKKEICINK
MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVY
LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLK
RKDFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA
LLHKILVENPSVRITIPDIKKDRWYNKPLKKGAKRPRATSGGVSESPGGFSKHIQSNLDF
SLVNSTSSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL
GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTVSTTDRR
NNKLIFKVNLVEMDEKILVDFRLSKGDGLEFKRHFLKIKGKLSDVVSSQKVWLPAT
NT seq 1431 nt   +upstreamnt  +downstreamnt
atggcagtgccctttgtggaagattgggacttggtgcaaaccctgggagaaggtgcctat
ggagaagttcaacttgctgtgaatagaataactgaagaggcagttgcagtgaagattgtg
gacatgaagcgtgccatagactgcccggaaaatattaagaaagagatttgtatcaataaa
atgttaaatcatgaaaatgtagtaaaattctatggtcacaggagagaaggcaatatccag
tatctatttttggagtactgcagtggaggagagctttttgacagaatagagccagacata
ggcatgcctgaacaggatgctcagaggttcttccaccaactcatggcaggagtggtttat
ctgcatggtattgggataacacatagggatattaagccagaaaatctcctgttggatgaa
agggataacctcaaaatctccgactttggcttggccacagtgtttcggcataataatcgt
gagcgtttattgaacaagatgtgtggtacattaccttatgttgctccagagcttctgaag
agaaaagattttcatgcagaaccagttgatgtttggtcctgtggaatagtacttactgca
atgctggctggagaattaccatgggaccagcccagtgacagttgtcaggaatattctgat
tggaaagaaaaaaaaacatacctcaatccttggaaaaaaatcgattctgcccctttagct
ctgctgcataaaatcctagttgagaatccatcagtaaggattaccattccagacataaaa
aaagatagatggtacaacaagccactcaagaaaggggcgaagagaccccgagccacttca
ggtggtgtatcagagtctcctggtggattttctaagcatattcaatccaatttggacttc
tctctggtaaacagtacttcgagtgaagaaaatgtgaaatattccagttctcaaccagag
ccacggacaggactctccttatgggacaccagtccttcatacattgataaactggtacaa
gggatcagtttttcccagcccacctgtcctgatcatatgcttttgaatagtcaattactt
ggcaccccaggatcctcacagaatccctggcaacgcttggtcaaaagaatgacgagattc
tttactaaactggatgcagacaaatcttatcagtgcttgaaggagacctgtgagaagttg
ggctatcagtggaagaagagttgtatgaatcaggttactgtatcgactactgacaggaga
aacaataaactgattttcaaagtgaatttggtagaaatggatgagaagatattggttgac
ttccgactttctaagggtgatggattggagttcaagagacacttcctgaagattaaaggg
aagctgagtgatgttgtgagcagccagaaagtttggcttcctgccacatga

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