KEGG   Oryctolagus cuniculus (rabbit): 100345812
Entry
100345812         CDS       T03373                                 

Gene name
TGFBR1
Definition
(RefSeq) transforming growth factor beta receptor 1
  KO
K04674  TGF-beta receptor type-1 [EC:2.7.11.30]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu04010  MAPK signaling pathway
ocu04060  Cytokine-cytokine receptor interaction
ocu04068  FoxO signaling pathway
ocu04144  Endocytosis
ocu04218  Cellular senescence
ocu04350  TGF-beta signaling pathway
ocu04371  Apelin signaling pathway
ocu04380  Osteoclast differentiation
ocu04390  Hippo signaling pathway
ocu04520  Adherens junction
ocu04659  Th17 cell differentiation
ocu04926  Relaxin signaling pathway
ocu04933  AGE-RAGE signaling pathway in diabetic complications
ocu05142  Chagas disease
ocu05161  Hepatitis B
ocu05166  Human T-cell leukemia virus 1 infection
ocu05200  Pathways in cancer
ocu05210  Colorectal cancer
ocu05212  Pancreatic cancer
ocu05220  Chronic myeloid leukemia
ocu05225  Hepatocellular carcinoma
ocu05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100345812 (TGFBR1)
   04350 TGF-beta signaling pathway
    100345812 (TGFBR1)
   04390 Hippo signaling pathway
    100345812 (TGFBR1)
   04371 Apelin signaling pathway
    100345812 (TGFBR1)
   04068 FoxO signaling pathway
    100345812 (TGFBR1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100345812 (TGFBR1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100345812 (TGFBR1)
  09143 Cell growth and death
   04218 Cellular senescence
    100345812 (TGFBR1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    100345812 (TGFBR1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    100345812 (TGFBR1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    100345812 (TGFBR1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100345812 (TGFBR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100345812 (TGFBR1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100345812 (TGFBR1)
   05212 Pancreatic cancer
    100345812 (TGFBR1)
   05225 Hepatocellular carcinoma
    100345812 (TGFBR1)
   05226 Gastric cancer
    100345812 (TGFBR1)
   05220 Chronic myeloid leukemia
    100345812 (TGFBR1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100345812 (TGFBR1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100345812 (TGFBR1)
   05161 Hepatitis B
    100345812 (TGFBR1)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    100345812 (TGFBR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ocu01001]
    100345812 (TGFBR1)
Enzymes [BR:ocu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     100345812 (TGFBR1)
Protein kinases [BR:ocu01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   100345812 (TGFBR1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Pkinase_fungal APH Activin_recp FTA2
Other DBs
NCBI-GeneID: 100345812
NCBI-ProteinID: XP_008260330
Ensembl: ENSOCUG00000016292
LinkDB
Position
1
AA seq 434 aa
MCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTVVKQSPGLGPVELAAV
IAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTTSGS
GSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIY
QTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALST
ASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAP
NHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYY
DLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIK
KTLSQLSQQEGIKM
NT seq 1305 nt   +upstreamnt  +downstreamnt
atgtgtatagcagaaattgacttaattcctcgagacaggccatttgtatgtgcaccctct
tcaaaaactggctctgttactacaacatactgctgcaatcaggaccattgcaataaaatc
gaactcccaactgttgtaaagcagtcacctggccttggtcctgtcgaactagcagctgtc
attgctggaccagtctgcttcgtctgcatctcactcatgttgatggtctatatctgccat
aaccgcacggtcattcaccaccgggtgccaaatgaggaggatccttcattagatcgccct
tttatttcagagggcaccacgttaaaagatttaatttatgatatgacaacatcgggttcg
ggatcaggtttaccattgcttgttcagagaacaattgcaaggactattgtgttacaagaa
agcattggcaaaggtcgatttggagaagtttggcgagggaagtggcggggagaggaagtg
gctgtgaagattttctcctccagggaggagcgctcctggttccgggaagcagagatttac
cagaccgtaatgttacgccatgagaacatcctggggttcattgcagcggataataaagat
aatggcacatggactcagctgtggttggtgtcggattaccatgagcatgggtcccttttt
gattacttgaacagatacacagtgaccgtggagggcatgatcaaacttgctctgtctaca
gccagtggtcttgcccatcttcacatggagattgttggtacccaaggaaaaccagccatt
gctcatagagatttgaaatcaaagaacatcttggtaaagaagaatggaacttgctgtatt
gcagacttgggactggcagtaagacatgattcagccacagatacaattgatattgctcca
aaccacagagtgggaacaaaaaggtacatggctcctgaagttctagatgattccataaat
atgaagcattttgaatccttcaaacgtgctgacatctatgcaatgggcttagtattctgg
gaaattgctcgacgatgttccattggtggaattcatgaggattaccagctgccttattat
gatcttgtaccttctgatccatcagttgaagaaatgagaaaagttgtttgtgaacagaag
ttaaggccaaatattccaaacagatggcagagctgtgaagccttgcgagtaatggctaaa
attatgagagaatgttggtatgccaatggagcagctcggctcacagctttgcggattaag
aaaacattgtcacagctcagtcagcaggaaggcatcaaaatgtaa

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