KEGG   Oryctolagus cuniculus (rabbit): 100352386
Entry
100352386         CDS       T03373                                 

Gene name
DDB2
Definition
(RefSeq) damage specific DNA binding protein 2
  KO
K10140  DNA damage-binding protein 2
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu03420  Nucleotide excision repair
ocu04115  p53 signaling pathway
ocu04120  Ubiquitin mediated proteolysis
ocu05161  Hepatitis B
ocu05169  Epstein-Barr virus infection
ocu05200  Pathways in cancer
ocu05202  Transcriptional misregulation in cancer
ocu05210  Colorectal cancer
ocu05212  Pancreatic cancer
ocu05213  Endometrial cancer
ocu05214  Glioma
ocu05216  Thyroid cancer
ocu05217  Basal cell carcinoma
ocu05218  Melanoma
ocu05220  Chronic myeloid leukemia
ocu05222  Small cell lung cancer
ocu05223  Non-small cell lung cancer
ocu05224  Breast cancer
ocu05225  Hepatocellular carcinoma
ocu05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    100352386 (DDB2)
  09124 Replication and repair
   03420 Nucleotide excision repair
    100352386 (DDB2)
 09140 Cellular Processes
  09143 Cell growth and death
   04115 p53 signaling pathway
    100352386 (DDB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100352386 (DDB2)
   05202 Transcriptional misregulation in cancer
    100352386 (DDB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100352386 (DDB2)
   05212 Pancreatic cancer
    100352386 (DDB2)
   05225 Hepatocellular carcinoma
    100352386 (DDB2)
   05226 Gastric cancer
    100352386 (DDB2)
   05214 Glioma
    100352386 (DDB2)
   05216 Thyroid cancer
    100352386 (DDB2)
   05220 Chronic myeloid leukemia
    100352386 (DDB2)
   05217 Basal cell carcinoma
    100352386 (DDB2)
   05218 Melanoma
    100352386 (DDB2)
   05213 Endometrial cancer
    100352386 (DDB2)
   05224 Breast cancer
    100352386 (DDB2)
   05222 Small cell lung cancer
    100352386 (DDB2)
   05223 Non-small cell lung cancer
    100352386 (DDB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    100352386 (DDB2)
   05169 Epstein-Barr virus infection
    100352386 (DDB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:ocu04121]
    100352386 (DDB2)
   03400 DNA repair and recombination proteins [BR:ocu03400]
    100352386 (DDB2)
Ubiquitin system [BR:ocu04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     100352386 (DDB2)
DNA repair and recombination proteins [BR:ocu03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      100352386 (DDB2)
SSDB
Motif
Pfam: WD40
Other DBs
NCBI-GeneID: 100352386
NCBI-ProteinID: XP_002709135
Ensembl: ENSOCUG00000002076
UniProt: G1SGS2
LinkDB
Position
1
AA seq 427 aa
MAPKKRPEAQKPLEVVLRPRSKRNRSPRDPEPEAKKLNVTGCAPGRRSDSDCLPAGLPGL
QDPQPCSSLVRALHQHRLGRTAWPSLQQGLQQSFLHSLASYRIFQKAAPFDRRATSLAWH
PTHPSTLAVGSKGGDIMLWNFRVKDRPTFIKGIGAGGSITGLKFNLLNTNQFFASSMEGT
TRLQDFTGNTLRVFTSSDTCNVWFCSLDVSARSRVVVTGDNMGHVFLLNMDGKELWNLRM
HKKKVTHVALNPSCDWLLATASVDQTVKIWDLRQVRGKASFLCSLPHKHPVNSACFSPDG
ARLLTTDQKNELRIYSASQWDCPVGLIPHPHRHFQHLTPIKASWHPRYNLIVVGRYPDPN
FKSCAPYELRTIDMFDGGSGKMMCQLYDPESSGIVSLNEFNPMGDTLASTMGYHILVWSQ
EEAGARK
NT seq 1284 nt   +upstreamnt  +downstreamnt
atggctcccaagaaacgccccgaagcccagaagcccctcgaggttgtgctgcgcccccgg
agcaagaggaaccgaagtccccgagacccagagcccgaggccaagaagctgaacgtcacg
ggctgcgctcctggcagaagatctgactcagactgcctcccggcggggttgcccggcctg
caggacccgcagccctgcagcagccttgtcagggccttgcaccagcacaggctgggcaga
accgcctggccatcgctgcaacagggtctccagcagtcctttttgcactctctggcttct
taccggatattccaaaaggctgccccatttgataggagggctacctccttggcctggcac
ccgactcaccccagcaccctggcagtgggttccaaagggggagacatcatgctgtggaac
tttagggtaaaggacagacccaccttcatcaaagggattggagctggagggagcatcact
gggctgaagtttaaccttctcaataccaaccagtttttcgcctcctcaatggagggaaca
actaggctgcaagactttacaggcaacaccctccgagtttttaccagctcagacacctgc
aacgtgtggttttgcagcctggacgtgtctgccagaagccgagtggtggtcacaggagac
aacatggggcacgtgtttctgctgaacatggacggtaaagagctctggaatctccgaatg
cacaaaaagaaagtgacccatgtggctctgaacccgagctgcgattggttactggccaca
gcctccgtagaccaaacagtgaaaatctgggacctgcgccaggttagagggaaagccagc
ttcctctgctcgctgccacacaagcatcctgtcaactcagcctgcttcagtcctgacgga
gcccggctcctgaccacggatcagaagaatgagctccggatttactctgcctcccagtgg
gactgccccgtgggcctcatcccgcatcctcaccggcacttccagcacctcactcccatc
aaggcaagctggcaccctcggtacaacctcattgtcgtgggtcggtacccagatcctaat
ttcaaaagttgcgctccctacgaactaaggacgattgacatgtttgacggaggctcaggg
aagatgatgtgtcagctctatgacccagaatcttctgggatcgtttcgcttaacgagttc
aatcccatgggggacacactggcctccacaatgggttatcacattctcgtttggagccag
gaagaagctggggcacggaaatga

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