Orcinus orca (killer whale): 101273287 Help Entry 101273287         CDS       T05247                                  Gene name MAPK1 Definition (RefSeq) mitogen-activated protein kinase 1   KO K04371   mitogen-activated protein kinase 1/3 [EC:2.7.11.24] Organism oor  Orcinus orca (killer whale) Pathway oor01521   EGFR tyrosine kinase inhibitor resistance oor01522   Endocrine resistance oor01524   Platinum drug resistance oor04010   MAPK signaling pathway oor04012   ErbB signaling pathway oor04014   Ras signaling pathway oor04015   Rap1 signaling pathway oor04022   cGMP-PKG signaling pathway oor04024   cAMP signaling pathway oor04062   Chemokine signaling pathway oor04066   HIF-1 signaling pathway oor04068   FoxO signaling pathway oor04071   Sphingolipid signaling pathway oor04072   Phospholipase D signaling pathway oor04114   Oocyte meiosis oor04140   Autophagy - animal oor04150   mTOR signaling pathway oor04151   PI3K-Akt signaling pathway oor04210   Apoptosis oor04218   Cellular senescence oor04261   Adrenergic signaling in cardiomyocytes oor04270   Vascular smooth muscle contraction oor04350   TGF-beta signaling pathway oor04360   Axon guidance oor04370   VEGF signaling pathway oor04371   Apelin signaling pathway oor04380   Osteoclast differentiation oor04510   Focal adhesion oor04520   Adherens junction oor04540   Gap junction oor04550   Signaling pathways regulating pluripotency of stem cells oor04611   Platelet activation oor04613   Neutrophil extracellular trap formation oor04620   Toll-like receptor signaling pathway oor04621   NOD-like receptor signaling pathway oor04625   C-type lectin receptor signaling pathway oor04650   Natural killer cell mediated cytotoxicity oor04657   IL-17 signaling pathway oor04658   Th1 and Th2 cell differentiation oor04659   Th17 cell differentiation oor04660   T cell receptor signaling pathway oor04662   B cell receptor signaling pathway oor04664   Fc epsilon RI signaling pathway oor04666   Fc gamma R-mediated phagocytosis oor04668   TNF signaling pathway oor04713   Circadian entrainment oor04720   Long-term potentiation oor04722   Neurotrophin signaling pathway oor04723   Retrograde endocannabinoid signaling oor04724   Glutamatergic synapse oor04725   Cholinergic synapse oor04726   Serotonergic synapse oor04730   Long-term depression oor04810   Regulation of actin cytoskeleton oor04910   Insulin signaling pathway oor04912   GnRH signaling pathway oor04914   Progesterone-mediated oocyte maturation oor04915   Estrogen signaling pathway oor04916   Melanogenesis oor04917   Prolactin signaling pathway oor04919   Thyroid hormone signaling pathway oor04921   Oxytocin signaling pathway oor04926   Relaxin signaling pathway oor04928   Parathyroid hormone synthesis, secretion and action oor04929   GnRH secretion oor04930   Type II diabetes mellitus oor04933   AGE-RAGE signaling pathway in diabetic complications oor04934   Cushing syndrome oor04935   Growth hormone synthesis, secretion and action oor04960   Aldosterone-regulated sodium reabsorption oor05010   Alzheimer disease oor05020   Prion disease oor05022   Pathways of neurodegeneration - multiple diseases oor05034   Alcoholism oor05132   Salmonella infection oor05133   Pertussis oor05135   Yersinia infection oor05140   Leishmaniasis oor05142   Chagas disease oor05145   Toxoplasmosis oor05152   Tuberculosis oor05160   Hepatitis C oor05161   Hepatitis B oor05163   Human cytomegalovirus infection oor05164   Influenza A oor05165   Human papillomavirus infection oor05166   Human T-cell leukemia virus 1 infection oor05167   Kaposi sarcoma-associated herpesvirus infection oor05170   Human immunodeficiency virus 1 infection oor05171   Coronavirus disease - COVID-19 oor05200   Pathways in cancer oor05203   Viral carcinogenesis oor05205   Proteoglycans in cancer oor05206   MicroRNAs in cancer oor05210   Colorectal cancer oor05211   Renal cell carcinoma oor05212   Pancreatic cancer oor05213   Endometrial cancer oor05214   Glioma oor05215   Prostate cancer oor05216   Thyroid cancer oor05218   Melanoma oor05219   Bladder cancer oor05220   Chronic myeloid leukemia oor05221   Acute myeloid leukemia oor05223   Non-small cell lung cancer oor05224   Breast cancer oor05225   Hepatocellular carcinoma oor05226   Gastric cancer oor05230   Central carbon metabolism in cancer oor05231   Choline metabolism in cancer oor05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:oor00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101273287 (MAPK1)    04012 ErbB signaling pathway     101273287 (MAPK1)    04014 Ras signaling pathway     101273287 (MAPK1)    04015 Rap1 signaling pathway     101273287 (MAPK1)    04350 TGF-beta signaling pathway     101273287 (MAPK1)    04370 VEGF signaling pathway     101273287 (MAPK1)    04371 Apelin signaling pathway     101273287 (MAPK1)    04668 TNF signaling pathway     101273287 (MAPK1)    04066 HIF-1 signaling pathway     101273287 (MAPK1)    04068 FoxO signaling pathway     101273287 (MAPK1)    04072 Phospholipase D signaling pathway     101273287 (MAPK1)    04071 Sphingolipid signaling pathway     101273287 (MAPK1)    04024 cAMP signaling pathway     101273287 (MAPK1)    04022 cGMP-PKG signaling pathway     101273287 (MAPK1)    04151 PI3K-Akt signaling pathway     101273287 (MAPK1)    04150 mTOR signaling pathway     101273287 (MAPK1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     101273287 (MAPK1)   09143 Cell growth and death    04114 Oocyte meiosis     101273287 (MAPK1)    04210 Apoptosis     101273287 (MAPK1)    04218 Cellular senescence     101273287 (MAPK1)   09144 Cellular community - eukaryotes    04510 Focal adhesion     101273287 (MAPK1)    04520 Adherens junction     101273287 (MAPK1)    04540 Gap junction     101273287 (MAPK1)    04550 Signaling pathways regulating pluripotency of stem cells     101273287 (MAPK1)   09142 Cell motility    04810 Regulation of actin cytoskeleton     101273287 (MAPK1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     101273287 (MAPK1)    04613 Neutrophil extracellular trap formation     101273287 (MAPK1)    04620 Toll-like receptor signaling pathway     101273287 (MAPK1)    04621 NOD-like receptor signaling pathway     101273287 (MAPK1)    04625 C-type lectin receptor signaling pathway     101273287 (MAPK1)    04650 Natural killer cell mediated cytotoxicity     101273287 (MAPK1)    04660 T cell receptor signaling pathway     101273287 (MAPK1)    04658 Th1 and Th2 cell differentiation     101273287 (MAPK1)    04659 Th17 cell differentiation     101273287 (MAPK1)    04657 IL-17 signaling pathway     101273287 (MAPK1)    04662 B cell receptor signaling pathway     101273287 (MAPK1)    04664 Fc epsilon RI signaling pathway     101273287 (MAPK1)    04666 Fc gamma R-mediated phagocytosis     101273287 (MAPK1)    04062 Chemokine signaling pathway     101273287 (MAPK1)   09152 Endocrine system    04910 Insulin signaling pathway     101273287 (MAPK1)    04929 GnRH secretion     101273287 (MAPK1)    04912 GnRH signaling pathway     101273287 (MAPK1)    04915 Estrogen signaling pathway     101273287 (MAPK1)    04914 Progesterone-mediated oocyte maturation     101273287 (MAPK1)    04917 Prolactin signaling pathway     101273287 (MAPK1)    04921 Oxytocin signaling pathway     101273287 (MAPK1)    04926 Relaxin signaling pathway     101273287 (MAPK1)    04935 Growth hormone synthesis, secretion and action     101273287 (MAPK1)    04919 Thyroid hormone signaling pathway     101273287 (MAPK1)    04928 Parathyroid hormone synthesis, secretion and action     101273287 (MAPK1)    04916 Melanogenesis     101273287 (MAPK1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     101273287 (MAPK1)    04270 Vascular smooth muscle contraction     101273287 (MAPK1)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     101273287 (MAPK1)   09156 Nervous system    04724 Glutamatergic synapse     101273287 (MAPK1)    04725 Cholinergic synapse     101273287 (MAPK1)    04726 Serotonergic synapse     101273287 (MAPK1)    04720 Long-term potentiation     101273287 (MAPK1)    04730 Long-term depression     101273287 (MAPK1)    04723 Retrograde endocannabinoid signaling     101273287 (MAPK1)    04722 Neurotrophin signaling pathway     101273287 (MAPK1)   09158 Development and regeneration    04360 Axon guidance     101273287 (MAPK1)    04380 Osteoclast differentiation     101273287 (MAPK1)   09159 Environmental adaptation    04713 Circadian entrainment     101273287 (MAPK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101273287 (MAPK1)    05206 MicroRNAs in cancer     101273287 (MAPK1)    05205 Proteoglycans in cancer     101273287 (MAPK1)    05203 Viral carcinogenesis     101273287 (MAPK1)    05230 Central carbon metabolism in cancer     101273287 (MAPK1)    05231 Choline metabolism in cancer     101273287 (MAPK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     101273287 (MAPK1)   09162 Cancer: specific types    05210 Colorectal cancer     101273287 (MAPK1)    05212 Pancreatic cancer     101273287 (MAPK1)    05225 Hepatocellular carcinoma     101273287 (MAPK1)    05226 Gastric cancer     101273287 (MAPK1)    05214 Glioma     101273287 (MAPK1)    05216 Thyroid cancer     101273287 (MAPK1)    05221 Acute myeloid leukemia     101273287 (MAPK1)    05220 Chronic myeloid leukemia     101273287 (MAPK1)    05218 Melanoma     101273287 (MAPK1)    05211 Renal cell carcinoma     101273287 (MAPK1)    05219 Bladder cancer     101273287 (MAPK1)    05215 Prostate cancer     101273287 (MAPK1)    05213 Endometrial cancer     101273287 (MAPK1)    05224 Breast cancer     101273287 (MAPK1)    05223 Non-small cell lung cancer     101273287 (MAPK1)   09164 Neurodegenerative disease    05010 Alzheimer disease     101273287 (MAPK1)    05020 Prion disease     101273287 (MAPK1)    05022 Pathways of neurodegeneration - multiple diseases     101273287 (MAPK1)   09165 Substance dependence    05034 Alcoholism     101273287 (MAPK1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101273287 (MAPK1)    04933 AGE-RAGE signaling pathway in diabetic complications     101273287 (MAPK1)    04934 Cushing syndrome     101273287 (MAPK1)   09171 Infectious disease: bacterial    05132 Salmonella infection     101273287 (MAPK1)    05135 Yersinia infection     101273287 (MAPK1)    05133 Pertussis     101273287 (MAPK1)    05152 Tuberculosis     101273287 (MAPK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101273287 (MAPK1)    05170 Human immunodeficiency virus 1 infection     101273287 (MAPK1)    05161 Hepatitis B     101273287 (MAPK1)    05160 Hepatitis C     101273287 (MAPK1)    05171 Coronavirus disease - COVID-19     101273287 (MAPK1)    05164 Influenza A     101273287 (MAPK1)    05163 Human cytomegalovirus infection     101273287 (MAPK1)    05167 Kaposi sarcoma-associated herpesvirus infection     101273287 (MAPK1)    05165 Human papillomavirus infection     101273287 (MAPK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     101273287 (MAPK1)    05140 Leishmaniasis     101273287 (MAPK1)    05142 Chagas disease     101273287 (MAPK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     101273287 (MAPK1)    01524 Platinum drug resistance     101273287 (MAPK1)    01522 Endocrine resistance     101273287 (MAPK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:oor01001]     101273287 (MAPK1)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:oor03036]     101273287 (MAPK1)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:oor04147]     101273287 (MAPK1) Enzymes [BR:oor01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.24  mitogen-activated protein kinase      101273287 (MAPK1) Protein kinases [BR:oor01001]  Serine/threonine kinases: CMGC group   MAPK family [OT]    101273287 (MAPK1) Chromosome and associated proteins [BR:oor03036]  Eukaryotic type   Centromeric chromatin formation proteins    SAC (spindle assembly checkpoint) factors     Protein kinases      101273287 (MAPK1) Exosome [BR:oor04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    101273287 (MAPK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr APH FTA2 Choline_kinase Kdo Kinase-like Motif Other DBs NCBI-GeneID:  101273287 NCBI-ProteinID:  XP_004276081 LinkDB All DBs Position Unknown AA seq 335 aa AA seqDB search MPSPLLPSFFIYFFSSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIG INDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANV LHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGY TKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLL SLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIA EAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS NT seq 1008 nt NT seq  +upstreamnt  +downstreamnt atgccatctcccctcctcccctccttttttatttatttttttagctctgcttatgataat gtcaacaaagttcgagtagctatcaagaaaatcagcccttttgagcaccagacctactgc cagagaaccctgagggagataaaaatcttactgcgcttcagacatgagaacatcattgga atcaatgatattattcgagcaccaaccatcgagcagatgaaagatgtatatatagtacaa gacctcatggaaacagatctctacaagctcttgaagacgcaacacctcagcaacgaccat atctgctattttctttaccagatcctcagagggttaaaatatatccattcagctaacgtg ctgcaccgtgacctcaaaccttccaacctgctgctcaacaccacctgcgatctcaagatc tgtgactttggcttggcccgtgttgcagatccggaccatgatcacacagggttcctgaca gagtacgttgccacacgttggtacagggctccggaaattatgttgaattccaagggctac accaagtccattgatatttggtctgtaggctgcatcctggcagagatgctctccaacagg cccatcttcccggggaagcattacctcgaccagctgaaccacattctgggtattcttgga tccccatcccaggaagacctgaattgtataataaatttaaaagctaggaactatttgctt tctcttccgcacaaaaataaggtgccatggaacaggctgttcccaaatgctgactccaaa gctctggatttactggacaagatgttgacgttcaaccctcataagaggattgaggtggaa caggctctggcccacccgtacctggagcagtactacgacccaagtgacgagcccatcgcc gaagcaccattcaagtttgacatggaattggatgacttgcccaaggaaaagctcaaagaa ctcatttttgaagagaccgctagattccagccaggatacagatcttaa

Orcinus orca (killer whale): 101289394 Help Entry 101289394         CDS       T05247                                  Gene name MAPK3 Definition (RefSeq) mitogen-activated protein kinase 3   KO K04371   mitogen-activated protein kinase 1/3 [EC:2.7.11.24] Organism oor  Orcinus orca (killer whale) Pathway oor01521   EGFR tyrosine kinase inhibitor resistance oor01522   Endocrine resistance oor01524   Platinum drug resistance oor04010   MAPK signaling pathway oor04012   ErbB signaling pathway oor04014   Ras signaling pathway oor04015   Rap1 signaling pathway oor04022   cGMP-PKG signaling pathway oor04024   cAMP signaling pathway oor04062   Chemokine signaling pathway oor04066   HIF-1 signaling pathway oor04068   FoxO signaling pathway oor04071   Sphingolipid signaling pathway oor04072   Phospholipase D signaling pathway oor04114   Oocyte meiosis oor04140   Autophagy - animal oor04150   mTOR signaling pathway oor04151   PI3K-Akt signaling pathway oor04210   Apoptosis oor04218   Cellular senescence oor04261   Adrenergic signaling in cardiomyocytes oor04270   Vascular smooth muscle contraction oor04350   TGF-beta signaling pathway oor04360   Axon guidance oor04370   VEGF signaling pathway oor04371   Apelin signaling pathway oor04380   Osteoclast differentiation oor04510   Focal adhesion oor04520   Adherens junction oor04540   Gap junction oor04550   Signaling pathways regulating pluripotency of stem cells oor04611   Platelet activation oor04613   Neutrophil extracellular trap formation oor04620   Toll-like receptor signaling pathway oor04621   NOD-like receptor signaling pathway oor04625   C-type lectin receptor signaling pathway oor04650   Natural killer cell mediated cytotoxicity oor04657   IL-17 signaling pathway oor04658   Th1 and Th2 cell differentiation oor04659   Th17 cell differentiation oor04660   T cell receptor signaling pathway oor04662   B cell receptor signaling pathway oor04664   Fc epsilon RI signaling pathway oor04666   Fc gamma R-mediated phagocytosis oor04668   TNF signaling pathway oor04713   Circadian entrainment oor04720   Long-term potentiation oor04722   Neurotrophin signaling pathway oor04723   Retrograde endocannabinoid signaling oor04724   Glutamatergic synapse oor04725   Cholinergic synapse oor04726   Serotonergic synapse oor04730   Long-term depression oor04810   Regulation of actin cytoskeleton oor04910   Insulin signaling pathway oor04912   GnRH signaling pathway oor04914   Progesterone-mediated oocyte maturation oor04915   Estrogen signaling pathway oor04916   Melanogenesis oor04917   Prolactin signaling pathway oor04919   Thyroid hormone signaling pathway oor04921   Oxytocin signaling pathway oor04926   Relaxin signaling pathway oor04928   Parathyroid hormone synthesis, secretion and action oor04929   GnRH secretion oor04930   Type II diabetes mellitus oor04933   AGE-RAGE signaling pathway in diabetic complications oor04934   Cushing syndrome oor04935   Growth hormone synthesis, secretion and action oor04960   Aldosterone-regulated sodium reabsorption oor05010   Alzheimer disease oor05020   Prion disease oor05022   Pathways of neurodegeneration - multiple diseases oor05034   Alcoholism oor05132   Salmonella infection oor05133   Pertussis oor05135   Yersinia infection oor05140   Leishmaniasis oor05142   Chagas disease oor05145   Toxoplasmosis oor05152   Tuberculosis oor05160   Hepatitis C oor05161   Hepatitis B oor05163   Human cytomegalovirus infection oor05164   Influenza A oor05165   Human papillomavirus infection oor05166   Human T-cell leukemia virus 1 infection oor05167   Kaposi sarcoma-associated herpesvirus infection oor05170   Human immunodeficiency virus 1 infection oor05171   Coronavirus disease - COVID-19 oor05200   Pathways in cancer oor05203   Viral carcinogenesis oor05205   Proteoglycans in cancer oor05206   MicroRNAs in cancer oor05210   Colorectal cancer oor05211   Renal cell carcinoma oor05212   Pancreatic cancer oor05213   Endometrial cancer oor05214   Glioma oor05215   Prostate cancer oor05216   Thyroid cancer oor05218   Melanoma oor05219   Bladder cancer oor05220   Chronic myeloid leukemia oor05221   Acute myeloid leukemia oor05223   Non-small cell lung cancer oor05224   Breast cancer oor05225   Hepatocellular carcinoma oor05226   Gastric cancer oor05230   Central carbon metabolism in cancer oor05231   Choline metabolism in cancer oor05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:oor00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101289394 (MAPK3)    04012 ErbB signaling pathway     101289394 (MAPK3)    04014 Ras signaling pathway     101289394 (MAPK3)    04015 Rap1 signaling pathway     101289394 (MAPK3)    04350 TGF-beta signaling pathway     101289394 (MAPK3)    04370 VEGF signaling pathway     101289394 (MAPK3)    04371 Apelin signaling pathway     101289394 (MAPK3)    04668 TNF signaling pathway     101289394 (MAPK3)    04066 HIF-1 signaling pathway     101289394 (MAPK3)    04068 FoxO signaling pathway     101289394 (MAPK3)    04072 Phospholipase D signaling pathway     101289394 (MAPK3)    04071 Sphingolipid signaling pathway     101289394 (MAPK3)    04024 cAMP signaling pathway     101289394 (MAPK3)    04022 cGMP-PKG signaling pathway     101289394 (MAPK3)    04151 PI3K-Akt signaling pathway     101289394 (MAPK3)    04150 mTOR signaling pathway     101289394 (MAPK3)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     101289394 (MAPK3)   09143 Cell growth and death    04114 Oocyte meiosis     101289394 (MAPK3)    04210 Apoptosis     101289394 (MAPK3)    04218 Cellular senescence     101289394 (MAPK3)   09144 Cellular community - eukaryotes    04510 Focal adhesion     101289394 (MAPK3)    04520 Adherens junction     101289394 (MAPK3)    04540 Gap junction     101289394 (MAPK3)    04550 Signaling pathways regulating pluripotency of stem cells     101289394 (MAPK3)   09142 Cell motility    04810 Regulation of actin cytoskeleton     101289394 (MAPK3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     101289394 (MAPK3)    04613 Neutrophil extracellular trap formation     101289394 (MAPK3)    04620 Toll-like receptor signaling pathway     101289394 (MAPK3)    04621 NOD-like receptor signaling pathway     101289394 (MAPK3)    04625 C-type lectin receptor signaling pathway     101289394 (MAPK3)    04650 Natural killer cell mediated cytotoxicity     101289394 (MAPK3)    04660 T cell receptor signaling pathway     101289394 (MAPK3)    04658 Th1 and Th2 cell differentiation     101289394 (MAPK3)    04659 Th17 cell differentiation     101289394 (MAPK3)    04657 IL-17 signaling pathway     101289394 (MAPK3)    04662 B cell receptor signaling pathway     101289394 (MAPK3)    04664 Fc epsilon RI signaling pathway     101289394 (MAPK3)    04666 Fc gamma R-mediated phagocytosis     101289394 (MAPK3)    04062 Chemokine signaling pathway     101289394 (MAPK3)   09152 Endocrine system    04910 Insulin signaling pathway     101289394 (MAPK3)    04929 GnRH secretion     101289394 (MAPK3)    04912 GnRH signaling pathway     101289394 (MAPK3)    04915 Estrogen signaling pathway     101289394 (MAPK3)    04914 Progesterone-mediated oocyte maturation     101289394 (MAPK3)    04917 Prolactin signaling pathway     101289394 (MAPK3)    04921 Oxytocin signaling pathway     101289394 (MAPK3)    04926 Relaxin signaling pathway     101289394 (MAPK3)    04935 Growth hormone synthesis, secretion and action     101289394 (MAPK3)    04919 Thyroid hormone signaling pathway     101289394 (MAPK3)    04928 Parathyroid hormone synthesis, secretion and action     101289394 (MAPK3)    04916 Melanogenesis     101289394 (MAPK3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     101289394 (MAPK3)    04270 Vascular smooth muscle contraction     101289394 (MAPK3)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     101289394 (MAPK3)   09156 Nervous system    04724 Glutamatergic synapse     101289394 (MAPK3)    04725 Cholinergic synapse     101289394 (MAPK3)    04726 Serotonergic synapse     101289394 (MAPK3)    04720 Long-term potentiation     101289394 (MAPK3)    04730 Long-term depression     101289394 (MAPK3)    04723 Retrograde endocannabinoid signaling     101289394 (MAPK3)    04722 Neurotrophin signaling pathway     101289394 (MAPK3)   09158 Development and regeneration    04360 Axon guidance     101289394 (MAPK3)    04380 Osteoclast differentiation     101289394 (MAPK3)   09159 Environmental adaptation    04713 Circadian entrainment     101289394 (MAPK3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101289394 (MAPK3)    05206 MicroRNAs in cancer     101289394 (MAPK3)    05205 Proteoglycans in cancer     101289394 (MAPK3)    05203 Viral carcinogenesis     101289394 (MAPK3)    05230 Central carbon metabolism in cancer     101289394 (MAPK3)    05231 Choline metabolism in cancer     101289394 (MAPK3)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     101289394 (MAPK3)   09162 Cancer: specific types    05210 Colorectal cancer     101289394 (MAPK3)    05212 Pancreatic cancer     101289394 (MAPK3)    05225 Hepatocellular carcinoma     101289394 (MAPK3)    05226 Gastric cancer     101289394 (MAPK3)    05214 Glioma     101289394 (MAPK3)    05216 Thyroid cancer     101289394 (MAPK3)    05221 Acute myeloid leukemia     101289394 (MAPK3)    05220 Chronic myeloid leukemia     101289394 (MAPK3)    05218 Melanoma     101289394 (MAPK3)    05211 Renal cell carcinoma     101289394 (MAPK3)    05219 Bladder cancer     101289394 (MAPK3)    05215 Prostate cancer     101289394 (MAPK3)    05213 Endometrial cancer     101289394 (MAPK3)    05224 Breast cancer     101289394 (MAPK3)    05223 Non-small cell lung cancer     101289394 (MAPK3)   09164 Neurodegenerative disease    05010 Alzheimer disease     101289394 (MAPK3)    05020 Prion disease     101289394 (MAPK3)    05022 Pathways of neurodegeneration - multiple diseases     101289394 (MAPK3)   09165 Substance dependence    05034 Alcoholism     101289394 (MAPK3)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101289394 (MAPK3)    04933 AGE-RAGE signaling pathway in diabetic complications     101289394 (MAPK3)    04934 Cushing syndrome     101289394 (MAPK3)   09171 Infectious disease: bacterial    05132 Salmonella infection     101289394 (MAPK3)    05135 Yersinia infection     101289394 (MAPK3)    05133 Pertussis     101289394 (MAPK3)    05152 Tuberculosis     101289394 (MAPK3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101289394 (MAPK3)    05170 Human immunodeficiency virus 1 infection     101289394 (MAPK3)    05161 Hepatitis B     101289394 (MAPK3)    05160 Hepatitis C     101289394 (MAPK3)    05171 Coronavirus disease - COVID-19     101289394 (MAPK3)    05164 Influenza A     101289394 (MAPK3)    05163 Human cytomegalovirus infection     101289394 (MAPK3)    05167 Kaposi sarcoma-associated herpesvirus infection     101289394 (MAPK3)    05165 Human papillomavirus infection     101289394 (MAPK3)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     101289394 (MAPK3)    05140 Leishmaniasis     101289394 (MAPK3)    05142 Chagas disease     101289394 (MAPK3)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     101289394 (MAPK3)    01524 Platinum drug resistance     101289394 (MAPK3)    01522 Endocrine resistance     101289394 (MAPK3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:oor01001]     101289394 (MAPK3)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:oor03036]     101289394 (MAPK3)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:oor04147]     101289394 (MAPK3) Enzymes [BR:oor01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.24  mitogen-activated protein kinase      101289394 (MAPK3) Protein kinases [BR:oor01001]  Serine/threonine kinases: CMGC group   MAPK family [OT]    101289394 (MAPK3) Chromosome and associated proteins [BR:oor03036]  Eukaryotic type   Centromeric chromatin formation proteins    SAC (spindle assembly checkpoint) factors     Protein kinases      101289394 (MAPK3) Exosome [BR:oor04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    101289394 (MAPK3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr APH Choline_kinase FTA2 Kdo NDUF_B4 Motif Other DBs NCBI-GeneID:  101289394 NCBI-ProteinID:  XP_004268688 LinkDB All DBs Position Unknown AA seq 383 aa AA seqDB search PAAAAAAAAAQGGGGGEPRGTDGVGPGVPGEVEIVKGQPFDVGPRYTQLQYIGEGAYGMV SSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMR DVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINT TCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILA EMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLF PKSDPKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFDMELDDLP KERLKELIFQETARFQPGVLEAP NT seq 1152 nt NT seq  +upstreamnt  +downstreamnt ccggcggcggcggcggcggcggcggcggctcaggggggcgggggcggggagccccgggga actgacggggtcggcccgggggtcccgggggaagtagagatagtaaaggggcagccgttc gacgtgggcccgcgctacacgcagctgcagtacatcggcgagggcgcgtatggcatggtc agctcagcttacgaccacgtgcgtaagactcgagtggccatcaagaaaatcagccccttt gagcatcagacctactgccagcgtacgttgcgagagatccagatcttgctgcgcttccgc cacgagaacgtcatcggcatccgagacattctgcgggcacccaccctggaagccatgagg gatgtctacattgtgcaagacctgatggagacagacctgtacaagttgcttaaaagccag cagctgagcaacgaccacatctgctacttcctctaccaaatcctgcggggcctcaagtat atccattccgccaacgtgctccaccgggatttaaagccctccaacctgctcattaacacc acctgcgaccttaagatctgtgattttggtcttgcccggattgccgatcctgagcacgac cacactggctttctgacggaatacgtggctacacgctggtaccgggccccagagatcatg cttaactccaagggctacaccaagtccatcgacatctggtctgtgggctgcattctggct gagatgctctccaaccggcccatcttcccgggcaagcactacctggaccagctcaaccac attctgggtatcctgggctccccctcccaggaggacctgaattgtatcatcaacatgaag gcccgaaactacctacagtctctaccctccaagaccaaggtggcctgggccaagcttttt cccaagtcggaccccaaagctcttgacctgctggaccggatgttgacctttaaccctaac aaacggatcacagtggaagaagcactggctcacccctacctggagcagtactacgaccca acagatgagccagtggccgaggaacctttcaccttcgacatggagctggatgatctaccc aaggagcggctgaaggagctcatcttccaggagacagcccgtttccagcctggggtgctg gaggccccctaa

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