Orcinus orca (killer whale): 101278255 Help Entry 101278255         CDS       T05247                                  Symbol HK2 Name (RefSeq) hexokinase-2 isoform X1   KO K00844   hexokinase [EC:2.7.1.1] Organism oor  Orcinus orca (killer whale) Pathway oor00010   Glycolysis / Gluconeogenesis oor00051   Fructose and mannose metabolism oor00052   Galactose metabolism oor00500   Starch and sucrose metabolism oor00520   Amino sugar and nucleotide sugar metabolism oor00524   Neomycin, kanamycin and gentamicin biosynthesis oor01100   Metabolic pathways oor01200   Carbon metabolism oor01250   Biosynthesis of nucleotide sugars oor04066   HIF-1 signaling pathway oor04910   Insulin signaling pathway oor04930   Type II diabetes mellitus oor04973   Carbohydrate digestion and absorption oor05230   Central carbon metabolism in cancer Module oor_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate oor_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose oor_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:oor00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     101278255 (HK2)    00051 Fructose and mannose metabolism     101278255 (HK2)    00052 Galactose metabolism     101278255 (HK2)    00500 Starch and sucrose metabolism     101278255 (HK2)    00520 Amino sugar and nucleotide sugar metabolism     101278255 (HK2)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     101278255 (HK2)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     101278255 (HK2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101278255 (HK2)   09154 Digestive system    04973 Carbohydrate digestion and absorption     101278255 (HK2)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     101278255 (HK2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101278255 (HK2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:oor04131]     101278255 (HK2) Enzymes [BR:oor01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      101278255 (HK2) Membrane trafficking [BR:oor04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     101278255 (HK2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 FGGY_N Motif Other DBs NCBI-GeneID:  101278255 NCBI-ProteinID:  XP_004277170 LinkDB All DBs Position 13:complement(25142753..25204311) Genome browser AA seq 917 aa AA seqDB search MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDETLLEIAKRFRKEMEKGLGATTHPTAS VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMR GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCLQTKLDESFLVSWTKGFKSSGV EGKDVVTLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYME EMRHIDMVEGDEGRMCINMEWGAFGDDGVLDDIRTEFDQEIDMGSLNPGKQLFEKMISGM YMGELVRLILVKMAKEELLFGGKLSPELLATGHFETKDVSDIEGEKDGIRKAREILVRLG LDPTQEDCVATHRVCQIVSTRSASLCAATLAAVLRRIKENKGEERLRSTIGVDGSVYKKH PHFAKRLHKTVRRLVPDCDIRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLESLKLS REQLLEVKRRMKVEMERGLSKETHTIAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV LLVRVRNGKRRGVEMHNKIYSIPREVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGF TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG TMMTCGYEDPHCEVGLIVGTGSNACYMEEMQNVELVEGEEGRMCVNMEWGAFGDNGCLDD FRTEFDAAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKHGLLFRGRISERLKTRG IFETKFLSQIESDCLALLQVRAILHHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA VVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLESEDGSGKG AALITAVACRIREAGQR NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgatcgcctcgcatctgctcgcctacttctttacggagctcaaccatgaccaagtgcag aaggttgaccagtatctctaccacatgcgtctttctgatgagaccctcctggagattgct aagcggttccgcaaggagatggagaaagggcttggagctaccacccaccccactgcttca gtaaaaatgctgcctacctttgtgaggtctactccagatgggacagaacatggagaattc ctggctctggaccttggagggaccaacttccgtgtgctttgggtgaaagtaacagacaat gggctccagaaggttgagatggagaaccagatctacgccattcctgaggacatcatgcga ggcagtggcacccagctgtttgaccacattgctgaatgcctggccaacttcatggataag ctacaaatcaaagacaagaagctccctttgggttttaccttctcattcccctgtctccaa acaaaactagacgagagtttcctggtctcatggaccaaggggttcaagtccagtggtgtg gaagggaaagatgtggttactctgatccggaaagccatccagaggagaggggactttgat attgacattgtggcagtggtgaatgacacagttgggaccatgatgacctgtggttatgat gaccagaactgcgagattggtcttattgtgggcacgggcagcaatgcttgctacatggaa gagatgcgccacatcgacatggtggagggtgacgagggccgtatgtgtatcaacatggag tggggagcctttggggatgatggcgtgcttgatgacatccgcacggagtttgaccaggag atcgacatgggctctctgaaccccgggaagcaactatttgagaagatgatcagtggaatg tacatgggggagctcgtgaggcttatcctagtgaagatggccaaggaggagctgcttttt ggggggaagctcagccctgaactcctcgccacgggccactttgagaccaaagatgtttca gatattgaaggggagaaggatggcatccggaaggcccgtgagatcctggtgcggctgggc ctggacccgacacaggaggactgtgtggccactcaccgggtctgccagatcgtgtccaca cgctcagccagcctgtgcgcggctacgctggcagccgtcctgcggcgcatcaaggagaac aagggcgaggagcggctgcgctccaccatcggggtggacggttctgtctacaagaagcat ccccatttcgccaagcgtcttcacaagaccgtgcggcgcctggtgcccgactgcgacatc cggttcctccgctctgaggacggcagtggcaagggggcagccatggtgacagcagtggcc taccggctggccgatcaacaccgagcccgccagaagaccctggagtctctgaagctgagc cgtgagcagctgctggaggtcaagaggaggatgaaggtagaaatggagcgaggtctgagc aaggagactcacaccattgcccccgtcaagatgctgcccacctatgtgtgtgccacccct gatggcacagagaaaggtgacttcctggccttggaccttgggggtaccaatttccgggtc ctgctggtgcgcgtgcggaatgggaagcgacgtggagtggagatgcacaacaagatctac tctatcccgcgggaggtcatgcatggcacaggggatgagctctttgaccacatcgtccag tgcattgccgacttccttgagtacatgggcatgaagggcgtgtccctgcctctgggtttc accttctccttcccctgccagcagaacagcctggacgagagcatcctcctcaagtggact aaaggcttcaaggcatctggctgcgagggtgaggacgtggttacactgctgaaggaagcc atccaccggcgagaggagtttgacctggatgtggttgctgtggtgaatgacacagttggg actatgatgacctgtggctatgaagaccctcactgtgaagttggcctcattgttggcacg ggcagcaatgcctgctacatggaggagatgcagaatgttgagctggtggaaggggaagag gggcggatgtgtgtcaacatggagtggggggccttcggggacaatggatgcctagatgac ttccgcacagaatttgatgcagctgtggatgaactttccctcaaccctggcaaacagagg ttcgagaaaatgatcagtggcatgtacttgggcgaaattgttcgtaacatcctcatcgat ttcaccaaacatgggctgctcttccgtggccgcatctcggagcggctcaagacacgggga atctttgaaaccaagttcctgtctcagattgagagtgactgcctggccctgctgcaggtc cgtgccatcctgcaccacttagggcttgagagcacctgtgatgacagcatcattgtcaag gaggtgtgcactgtggtggcgcggcgggcagcccaactctgtggtgcaggcatggccgcc gtggtggacaaaatacgagagaaccgtgggctggacaccctcaaagtgacagtgggcgtg gatgggaccctctacaagctacatcctcactttgccaaagtcatgcatgagacggtgaag gacttggctccaaaatgtgatgtgtccttcctggagtcggaggatggcagcgggaagggg gcggctctcatcactgctgtggcctgccgcatccgagaggctggacagcggtag

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