Orcinus orca (killer whale): 101279538
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Entry
101279538 CDS
T05247
Symbol
ALOX12
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX12 isoform X3
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00590
Arachidonic acid metabolism
oor01100
Metabolic pathways
oor01523
Antifolate resistance
oor04726
Serotonergic synapse
oor04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
101279538 (ALOX12)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
101279538 (ALOX12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101279538 (ALOX12)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101279538 (ALOX12)
Enzymes [BR:
oor01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
101279538 (ALOX12)
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Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
101279538
NCBI-ProteinID:
XP_004267009
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Position
19:11506988..11519006
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AA seq
663 aa
AA seq
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MGRYRIRVATGAAFFAGSHDRVQLWLVGARGETELELQLLPARGQEEEFEHDIPEDLGPL
QFVKLRKHHSLVDNAWFCDHITVQGPVAFQEATFPCYRWVQADSVLCLPEGTARLAGNNA
LDVFQKHREKELKERRQIYCWATWKEGLPLTIAAGCEDDLPANMRFHEEKRLDFEGTLKA
GALEMVLKHVYTLLSSWNCFEDFDHIFWGQKNTLAEKVRQRWQDDELFGYQFLNGTNPML
LRRCTSLPSRLVLPAGMEELRTQLEKELQNSSLFEADFILLDGIPANVIRGEKQYLAAPL
VMLKMDTSGKLLPMVIQIQPPSPSSPTPPLFLPSDPPLAWLLAKSWVRNSDFQLHQLQYH
LLNTHLLAEVIAVATMRCLPGLHPVFKLLIPHIRYTMEINTRARTQLLPDGGIFDKAVST
GGGGHVHLLRRALAQLTYCSLCPPNNLADRGLLGTPGALYACDALRLWEITARYVEGIIH
LFYRGDDVVRGDPELQAWCREITEVGLCQAQNRGFPISFQSQNQLCHFLTMCVFTCTAQH
GAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTVATVMGSLPDVRQACLQMVVTWHLGRR
QPDMVPLGHHKEKYFSDPKAKSVLNQFQTDLENLEREITARNEQLDLPYEYLKPSLIENS
ITI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctaccgcatccgcgtggccaccggggccgcattcttcgccgggtcgcacgac
cgcgtgcagctgtggctggtcggggcgcgcggggagacggagctggagctgcagctgttg
ccggcgcggggccaggaggaggagtttgagcatgacattcccgaggacttgggaccactg
cagttcgtgaagctgcgcaaacaccactccctggtggacaacgcgtggttctgcgaccac
atcacggtgcagggccctgtagccttccaggaggccaccttcccgtgctaccgctgggtg
caggccgacagcgtgctgtgcctgcccgagggcaccgcccgcctggcaggaaacaacgca
ttggatgtgttccagaaacatcgagagaaggaactgaaagaaagacgtcagatatactgc
tgggccacatggaaggaagggttacccctgacaatagctgcgggctgtgaggacgatcta
cctgccaatatgagattccacgaggaaaagaggctggactttgaggggacactgaaggca
ggggctctggagatggtcctcaaacatgtttacaccctcctgagctcctggaactgcttt
gaggattttgatcacatcttctggggccagaagaataccctggctgagaaggttcgccag
cgctggcaggacgatgaattgtttggctaccagttcctcaatggcaccaatcccatgctg
ttgagacgctgcacctctctgccctcccggctagtgctgcccgcggggatggaggagcta
cggacccagctggagaaagaactccagaacagttccctgtttgaggctgatttcattctc
ctcgatggaattccagccaatgtgatccgaggagagaagcagtacctggctgcccccctc
gtcatgctgaagatggacaccagtgggaagctgctacccatggtcatccagatccagcct
cccagccccagctctccgaccccaccactgttcctgccctcagatcctccacttgcctgg
ctcctggcaaagtcctgggtccgaaattcagatttccaattgcaccagctccaatatcat
ctgctgaacacccacctgctggctgaggtcattgctgtggccaccatgaggtgcctcccg
gggctgcacccggtcttcaagctcctgattccacacatccgctacacgatggaaatcaac
acccgggcacggacccaactcctcccagacggaggtatatttgataaggcagtgagcacc
ggtggagggggccacgtgcacttgctccgccgggccctggctcagctgacctactgctcc
ctctgtcctcccaacaatctggctgaccgcggcctgctgggaaccccgggtgctctctat
gcctgcgatgctttacggctctgggagatcactgcccgctacgtggaggggatcatccac
cttttctaccgcggggatgacgtcgtgagaggggaccctgagctgcaggcctggtgtcgg
gagatcactgaggtggggctgtgccaggcccagaaccgaggtttccccatctccttccag
tcccagaatcaactctgccatttccttaccatgtgtgtcttcacgtgcactgctcagcat
ggggccatcaaccagggccagctggactggtatgcctgggtccctaatgccccatgcaca
atgcggatgcccccacctaccaccaaggaagatgtgacagtggccacggtgatgggctca
ctacctgatgtccgacaggcctgtcttcaaatggtcgtcacatggcatctggggcgccgc
cagccagacatggtgcctctggggcatcacaaagaaaagtatttctcagaccccaaggcc
aagtctgtactaaaccaattccaaacagatctggaaaacttggaaagggagattacagcc
cggaatgagcaacttgacctgccctatgaatacctaaagcccagcctcatcgagaacagc
atcactatctga
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