KEGG   Orcinus orca (killer whale): 101280796Help
Entry
101280796         CDS       T05247                                 

Gene name
EZH2
Definition
(RefSeq) histone-lysine N-methyltransferase EZH2 isoform X1
  KO
K11430  histone-lysine N-methyltransferase EZH2 [EC:2.1.1.43]
Organism
oor  Orcinus orca (killer whale)
Pathway
oor00310  Lysine degradation
oor05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:oor00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    101280796 (EZH2)
 09160 Human Diseases
  09161 Cancers
   05206 MicroRNAs in cancer
    101280796 (EZH2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:oor03036]
    101280796 (EZH2)
Enzymes [BR:oor01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     101280796 (EZH2)
Chromosome and associated proteins [BR:oor03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     101280796 (EZH2)
   Polycomb group proteins
    PRC2-EZH2 complex
     101280796 (EZH2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: SET EZH2_WD-Binding
Motif
Other DBs
NCBI-GeneID: 101280796
NCBI-ProteinID: XP_004283695
LinkDB All DBs
Position
Unknown
AA seq 751 aa AA seqDB search
MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEW
KQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNF
MVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQ
YNDDDDDDDGDDPDEREEKQKDLEENREDKESRPPRKFPSDKIFEAISSMFPDKGTAEEL
KEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHRKC
SYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRR
GRLPNNSSRPGTPTTNVLESKDTDSDREAGTETGGEGNDKEEEEKKDETSSSSEANSRCQ
TPIKMKPNAEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESS
VIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCP
CVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWD
SKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRG
KVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRA
IQTGEELFFDYRYSQADALKYVGIEREMEIP
NT seq 2256 nt NT seq  +upstreamnt  +downstreamnt
atgggccagactgggaagaaatctgagaagggaccagtgtgttggcggaagcgtgtaaag
tcagagtacatgcgcctgcggcagctcaagaggttcaggcgagctgacgaagtcaagagt
atgtttagttccaatcgtcagaaaattttggaaagaacagaaatcttaaaccaagaatgg
aaacagcgaaggatccagcctgtgcacatcctgacttctgtgagctcattgcgcgggacc
agggagtgttcggtgaccagtgacttggattttccaacacaagtcatcccgttaaagact
ctgaatgcagttgcttcagtacccataatgtattcttggtctcctctacagcagaatttc
atggtggaagatgaaactgttttacataacattccttacatgggggatgaagttttagac
caggacgggactttcattgaagaactaataaaaaattatgatggaaaagtacacggggat
agagaatgtgggtttataaatgatgaaatttttgtggagttggtgaatgctcttggtcaa
tacaatgacgatgatgatgatgatgatggagatgatcctgatgaaagagaagaaaaacag
aaagatctagaggagaaccgagaagataaagaaagtcgcccacctcggaaatttccttct
gataaaatttttgaagctatttcctcaatgtttccagataagggcacagcagaagagcta
aaggaaaagtacaaagaactcactgagcagcagctcccaggtgcacttccccctgagtgt
acccccaacatagatggaccaaacgccaagtctgttcagagggagcagagcttgcactca
tttcatacgcttttctgtaggcgatgttttaaatatgactgcttcctacatcgtaagtgc
agttattcttttcatgcgacacccaacacttacaagcggaagaacacagagacggctctg
gacaacaagccttgcggcccccagtgttaccagcacttggagggcgcgaaggagtttgct
gccgccctcactgccgagcggataaagacgcccccgaagcgcccaggcggccgcaggaga
gggcggctccccaacaacagcagcaggcccggcacccccaccaccaacgtgctcgagtcg
aaggacacggacagtgacagggaggcggggaccgagaccggaggggagggcaacgacaag
gaagaggaggagaagaaggacgagacctccagttcctcagaagcgaattctcggtgtcaa
acaccaataaagatgaagcccaacgccgagccccccgagaacgtggagtggagtggtgct
gaggcctccatgttcagggtcctcatcggcacgtactacgacaatttctgtgccatcgcc
aggttgattgggaccaaaacatgtcgacaggtgtatgagtttcgagtcaaagaatccagt
gtcatagcgccagcccccgccgaggacgttgacacccctcccaggaagaagaagaggaaa
caccggttgtgggctgcgcactgcagaaagatacagctgaagaaggatggctcctccaac
catgtttacaactaccagccctgtgaccacccacggcagccttgtgacagctcgtgccct
tgtgtgatagcccagaatttttgtgaaaagttttgtcaatgtagttcagagtgtcagaac
cgctttccgggatgccgctgcaaagcccagtgcaacaccaagcagtgcccgtgctacctg
gctgtccgagagtgtgaccccgacctctgtcttacttgtggagccgctgaccactgggac
agtaaaaacgtgtcctgcaagaactgtagcattcagcggggctctaagaagcatttattg
ctagcaccatctgatgtggcaggctgggggattttcatcaaagatcctgtacagaagaac
gaattcatctcggaatactgcggagagattatttctcaagatgaagcagacagaagaggg
aaagtatatgataaatacatgtgcagctttctcttcaacttgaacaatgattttgtggtg
gatgcaacccgcaagggtaacaaaattcgttttgcaaatcactcagtaaatccaaactgc
tatgcaaaagtgatgatggttaacggcgatcacaggatagggatttttgctaagagagcc
atccagactggtgaagagctgttttttgattacagatacagccaggctgacgccctcaag
tacgtgggcatcgaaagagaaatggaaatcccttga

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