Orcinus orca (killer whale): 101283619
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Entry
101283619 CDS
T05247
Gene name
ERBB2
Definition
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor01521
EGFR tyrosine kinase inhibitor resistance
oor01522
Endocrine resistance
oor01524
Platinum drug resistance
oor04010
MAPK signaling pathway
oor04012
ErbB signaling pathway
oor04020
Calcium signaling pathway
oor04066
HIF-1 signaling pathway
oor04151
PI3K-Akt signaling pathway
oor04510
Focal adhesion
oor04520
Adherens junction
oor04530
Tight junction
oor05200
Pathways in cancer
oor05205
Proteoglycans in cancer
oor05206
MicroRNAs in cancer
oor05212
Pancreatic cancer
oor05213
Endometrial cancer
oor05215
Prostate cancer
oor05219
Bladder cancer
oor05223
Non-small cell lung cancer
oor05224
Breast cancer
oor05226
Gastric cancer
oor05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101283619 (ERBB2)
04012 ErbB signaling pathway
101283619 (ERBB2)
04066 HIF-1 signaling pathway
101283619 (ERBB2)
04020 Calcium signaling pathway
101283619 (ERBB2)
04151 PI3K-Akt signaling pathway
101283619 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101283619 (ERBB2)
04520 Adherens junction
101283619 (ERBB2)
04530 Tight junction
101283619 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101283619 (ERBB2)
05206 MicroRNAs in cancer
101283619 (ERBB2)
05205 Proteoglycans in cancer
101283619 (ERBB2)
05230 Central carbon metabolism in cancer
101283619 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
101283619 (ERBB2)
05226 Gastric cancer
101283619 (ERBB2)
05219 Bladder cancer
101283619 (ERBB2)
05215 Prostate cancer
101283619 (ERBB2)
05213 Endometrial cancer
101283619 (ERBB2)
05224 Breast cancer
101283619 (ERBB2)
05223 Non-small cell lung cancer
101283619 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101283619 (ERBB2)
01524 Platinum drug resistance
101283619 (ERBB2)
01522 Endocrine resistance
101283619 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oor01001
]
101283619 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
oor04147
]
101283619 (ERBB2)
04090 CD molecules [BR:
oor04090
]
101283619 (ERBB2)
Enzymes [BR:
oor01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101283619 (ERBB2)
Protein kinases [BR:
oor01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
101283619 (ERBB2)
Exosome [BR:
oor04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
101283619 (ERBB2)
CD molecules [BR:
oor04090
]
Proteins
101283619 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
APH
Kinase-like
Motif
Other DBs
NCBI-GeneID:
101283619
NCBI-ProteinID:
XP_004282780
LinkDB
All DBs
Position
Unknown
AA seq
1255 aa
AA seq
DB search
MELAAWCRWGLLLALLPPGAAGTQVCTGTDMKLRPLASPETHLDMLRHLYQGCQVVQGNL
ELTYLPANASLSFLQEIQEVQGYVLIAQNRVSQVPLQRLRIVRGTQLFEDNYALAVLDNG
GLLEGAPPAARAAPGGLQELQLRSLTEILKGGVLIQRNPQLCHQDTIVWKDIFHRNNQLA
LMQIDTNRSRACPPCSPACKAPHCWGESSKDCQSLTRTVCASGCARCKGPQPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTTCP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQEFAGCKKIFGSLAFVPESFEGDQASNTAPLQPEQLRVFESLEEITGYLYISAWPDSLP
DLHVFQNLRVIRGRVLHDGAYSLTLQGLGIRWLGLRSLRELGSGLALIHRNARLCFVHTV
PWDQLFRNPHQALLHSANRPEVECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQQC
VEECRVLQGLPREYVKDRYCLPCHPECQPQNGSVTCFGSEADQCVACTHYKDPPFCVARC
PSGVKPDLSFMPIWKFPDEEGMCQPCPINCTHSCVDLDDKGCPAEQRASPVTSIIAAVVG
ILLVVVVGLVFGILVKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPPSPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGSGGTAHHRHRSTSTRSGGGELTLGLEPSEEEPPTSPLAPSEG
AGSDVFDGDLGMGAAKGLQNLPQHDSSPLQRYSEDPTEPLPPETDGYVAPLTYSPQPEYV
NQPEVRPQPPSPLEGPRPPPRPAGSTLERPKTLSPGKNGVVKDIFAFGAAVENPEYLAPR
GRAAPQSHSSPAFSPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPEYLGLDMPV
NT seq
3768 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccccccggagcc
gcgggcacccaagtgtgcaccggcacagacatgaagctgcggccgctggccagtcccgag
acccacctggacatgctccgccacctctaccagggctgtcaggtggtgcagggtaacctg
gagctcacctacctgcccgctaatgccagcctttccttcctgcaggagatccaggaggtg
cagggctacgtgctcatcgctcagaaccgagtgagtcaggtccccctgcagaggctgcgg
atcgtgcgaggcacccagctctttgaggacaactatgccctggccgtgctggacaacgga
ggccttctggaaggtgccccccctgctgcacgcgctgctccgggagggctgcaggagctg
cagctgcgaagcctcacagagatcctgaagggaggggtcttgatccagcggaacccccag
ctctgccaccaggacacgattgtgtggaaggacatcttccacaggaacaaccagctggcc
ctcatgcagatagacaccaaccgctcacgggcctgcccaccctgttctccagcttgtaaa
gctccccactgctggggagaaagttccaaggactgtcagagcttgacgcgaaccgtctgt
gccagcggctgtgcccgctgtaagggcccgcagcccaccgactgctgccacgagcagtgt
gctgccggctgcacgggccccaagcactctgactgtctggcctgcctccacttcaaccac
agtggcatctgtgagctgcactgcccagctctggtcacctacaacacggacaccttcgag
tccatgcccaaccccgagggccgttataccttcggcgccagctgcgtgaccacctgtcct
tacaactacctgtccacggacgtgggatcctgcaccctggtttgtcccctgaacaaccaa
gaggtgacagctgaggatggaacccagcggtgtgagaaatgcagcaagccctgtgcccga
gtgtgctatggtctgggcatggaacacctgcgggaggtgagggcggtcaccagtgccaac
atccaggagtttgctggctgcaagaagatctttgggagcctggcgtttgtgccggagagc
tttgagggggaccaagcctccaacactgcccccctacagcctgagcagctcagagtattt
gagtctctggaggagatcacaggttacctgtacatctcagcgtggccagacagcctgccg
gacctccacgtcttccagaatctgcgagtaatccggggacgagttctgcatgatggtgcc
tactcgctgaccctgcaagggctgggcatccgctggctggggctgcgctctctgcgggaa
ctgggcagtgggctggccctcatccaccgcaacgcccgcctctgctttgtacacacggtg
ccctgggaccagctcttccggaacccccaccaggccctgctccacagtgccaaccggcca
gaggtcgagtgcgtgggcgagggcctggcctgctacccgctgtgtgcccacgggcactgc
tggggtccagggcccacccagtgcgtcaactgcagccagttcctccggggccagcagtgc
gtggaagaatgccgagtactgcaggggctcccccgggagtacgtgaaggacaggtactgt
ctgccgtgccaccccgagtgtcagccccagaatggctcagtgacctgctttggctcggag
gctgaccagtgtgtggcttgcacccactacaaggatcctcccttctgcgtggctcgctgc
cccagtggtgtgaagcctgacctctccttcatgcccatctggaagttcccagatgaggag
ggcatgtgccagccatgccccatcaactgcacccactcctgtgtggacctggatgacaag
ggctgccccgctgagcagagagccagccccgtgacgtccatcattgccgctgtggtgggc
attctgctggtcgtcgtcgtggggctggtcttcggcatcctcgtcaagcggcggcggcag
aagatccgaaagtacacgatgcggcggctgctgcaggagacagagctggtggagcccctg
acaccgagcggagcgatgccaaatcaggctcagatgcggatcctgaaagagacagagctg
aggaaggtgaaggtgcttggatccggagcttttggtaccgtctacaagggcatctggatc
cccgatggggaaaatgtgaaaatcccagtggccatcaaagtgttgagggaaaacacatcc
cccaaagccaacaaagaaatcttggacgaagcatatgtgatggctggtgtagggtcccca
tacgtgtcccgccttctgggcatctgcctgacatccacggtgcagctggtgacacagctt
atgccctatggctgcctcctagaccacgtccgggagcaccgcgggcgcctgggctcccag
gacctgctgaactggtgtgtgcagattgccaaggggatgagctacttggaggatgtgcgg
ctcgtgcacagggacctagctgcccggaatgtgctggtcaagagtcccaaccatgtcaag
attacagacttcgggctggctcggctgctggacattgatgagacagagtaccatgcggat
gggggcaaggtgcccatcaagtggatggcgttggagtccattctccgccggcggttcacc
caccagagtgatgtgtggagctatggtgtgactgtgtgggagctgatgacttttggggcc
aaaccttacgatgggatcccagcccgggagatccctgacctcctggagaagggggagcgg
ctgccccagccccccatctgcaccattgatgtctacatgatcatggtcaaatgttggatg
atcgactctgaatgtcggccaaggttccgggagttggtggccgaattctcccgcatggcc
agggacccccagcgctttgtggtcatccagaatgaagacttgggccctcccagccccttg
gacagcaccttctaccgctcgctgctggaggatgatgacatgggggacctggtggatgct
gaggagtacctggtaccccagcaaggcttcttctgcccagaccctgccccgggctctggg
ggcacagcccaccacaggcaccgcagcacatccaccaggagtggcggtggtgagctgacg
ctgggtctggagccctcggaggaggagccccccacgtctccactggcaccttccgaaggg
gctggctctgatgtgtttgacggcgacttgggaatgggggcagccaaggggctgcagaac
ctcccccaacatgactccagccctctacagcggtacagcgaggaccccacagaaccgctt
cctcccgagaccgatggctacgttgcccccctgacctacagcccccagcccgaatacgtg
aaccagccagaggttcggccacagcccccctcacccctagagggtcctcggcctcctcct
cgacctgccggttccactctggaaaggcccaagactctctcccctgggaagaatggggtt
gtcaaagacatttttgcctttggggctgccgtggagaaccccgagtacttggcaccccgg
ggcagggctgcccctcagtcccactcttctccggccttcagcccagcctttgacaacctc
tattactgggaccaggacccatcagagcggggctctccacccagcacctttgaagggacc
cctacagcagagaaccctgagtacctgggtctggacatgccagtatga
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integrated database retrieval system
