Orcinus orca (killer whale): 101286234 Help Entry 101286234         CDS       T05247                                  Gene name MDM2 Definition (RefSeq) E3 ubiquitin-protein ligase Mdm2   KO K06643   E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27] Organism oor  Orcinus orca (killer whale) Pathway oor01522   Endocrine resistance oor01524   Platinum drug resistance oor04068   FoxO signaling pathway oor04110   Cell cycle oor04115   p53 signaling pathway oor04120   Ubiquitin mediated proteolysis oor04144   Endocytosis oor04151   PI3K-Akt signaling pathway oor04218   Cellular senescence oor04625   C-type lectin receptor signaling pathway oor04919   Thyroid hormone signaling pathway oor05163   Human cytomegalovirus infection oor05165   Human papillomavirus infection oor05169   Epstein-Barr virus infection oor05200   Pathways in cancer oor05202   Transcriptional misregulation in cancer oor05203   Viral carcinogenesis oor05205   Proteoglycans in cancer oor05206   MicroRNAs in cancer oor05214   Glioma oor05215   Prostate cancer oor05218   Melanoma oor05219   Bladder cancer oor05220   Chronic myeloid leukemia Brite KEGG Orthology (KO) [BR:oor00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     101286234 (MDM2)  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     101286234 (MDM2)    04151 PI3K-Akt signaling pathway     101286234 (MDM2)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     101286234 (MDM2)   09143 Cell growth and death    04110 Cell cycle     101286234 (MDM2)    04115 p53 signaling pathway     101286234 (MDM2)    04218 Cellular senescence     101286234 (MDM2)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     101286234 (MDM2)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     101286234 (MDM2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101286234 (MDM2)    05202 Transcriptional misregulation in cancer     101286234 (MDM2)    05206 MicroRNAs in cancer     101286234 (MDM2)    05205 Proteoglycans in cancer     101286234 (MDM2)    05203 Viral carcinogenesis     101286234 (MDM2)   09162 Cancer: specific types    05214 Glioma     101286234 (MDM2)    05220 Chronic myeloid leukemia     101286234 (MDM2)    05218 Melanoma     101286234 (MDM2)    05219 Bladder cancer     101286234 (MDM2)    05215 Prostate cancer     101286234 (MDM2)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     101286234 (MDM2)    05169 Epstein-Barr virus infection     101286234 (MDM2)    05165 Human papillomavirus infection     101286234 (MDM2)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     101286234 (MDM2)    01522 Endocrine resistance     101286234 (MDM2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:oor04131]     101286234 (MDM2)    04121 Ubiquitin system [BR:oor04121]     101286234 (MDM2) Enzymes [BR:oor01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      101286234 (MDM2) Membrane trafficking [BR:oor04131]  Endocytosis   Clathrin-mediated endocytosis    Ubiquitin E3 ligases     101286234 (MDM2) Ubiquitin system [BR:oor04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    MDM2/MDM4 proteins     101286234 (MDM2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  zf-C3HC4_3 SWIB zf-RanBP zf-RING_2 zf-FPG_IleRS Motif Other DBs NCBI-GeneID:  101286234 NCBI-ProteinID:  XP_012392920 LinkDB All DBs Position Unknown AA seq 491 aa AA seqDB search MCNTNMSVSTDGAVSTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVIFYLGQY IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVIVNQQEPSDSGT SVSENRCHLEGGSVQKDLVQELQEEKPSSSDLVSRPSTSSRRRAVSETEENSDELPGERQ RKRHKSDNISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDS VSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYRVTVYQAGESDTDSFEEDPEISLA DYWKCTSCSEMNPPLPPHCNRCWALRENWLPEDKGKDKGKMSEKAKLENSAQVEEGFDVP DCKKSTVNDSKESCVEENDDKITQASLSQESEDYSQPSTSNSIIYSSQEDVKELEREETQ DKEESVESSFPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQ PIQMIVLTYFP NT seq 1476 nt NT seq  +upstreamnt  +downstreamnt atgtgcaataccaacatgtctgtgtctactgatggtgctgtaagcacctcacagattcca gcttcggaacaagagaccctggttagaccaaagccattgcttttgaagttgttgaagtct gttggtgcacagaaggacacctatactatgaaagaggttatattttatcttggccagtat attatgactaaacgattatatgatgagaaacaacagcatattgtgtattgttcaaatgat cttctaggggatttgtttggagtgccaagcttctctgtgaaagagcacaggaaaatatat acaatgatttatagaaacttggtgatagtcaatcagcaggaaccatcagattcaggcaca tctgtgagtgaaaacaggtgtcaccttgaaggtgggagtgttcaaaaggaccttgtgcaa gagctacaggaagagaaaccttcatcttcagatttggtttctagaccatctacctcatct agaaggagagcagttagtgagacagaagaaaattcagatgaattacctggtgaacgacaa agaaagcgccacaaatctgataatatttccctttcctttgatgaaagccttgctctgtgt gtaataagggagatatgttgtgaaagaagcagtagcagtgaatcgacagggactccatca aatccggatcttgatgctggtgtaagtgaacattcaggtgattggttggatcaggattca gtttcagatcaattcagtgtagaatttgaagttgagtctctggattcagaagattatagc cttagtgaagaaggacaagaactctcagatgaagatgatgaggtatatcgagttactgtg tatcaggcaggggagagtgatacagattcatttgaagaagatcctgaaatttccttagct gactattggaagtgtacttcatgcagtgaaatgaatcctccccttccacctcattgcaac agatgttgggcccttcgtgaaaattggcttcctgaagataaagggaaagataaagggaaa atgtctgagaaagccaaactagaaaactcagcacaagtagaagagggctttgatgtccct gactgtaagaaatctacagtgaatgattccaaagaatcatgtgttgaggaaaatgatgat aagatcacacaagcctccctatcccaagaaagtgaggactattctcagccatcaacttct aatagtatcatttatagcagccaagaagatgtcaaagagttggagagggaagaaacacaa gacaaagaagaaagtgtggaatctagttttcctcttaatgccattgaaccttgtgtgatt tgccaaggtcgacctaaaaatggttgcatagtccatggcaaaacaggacatcttatggca tgctttacatgtgccaagaagctaaagaaaaggaataagccctgccccgtatgcagacaa ccaattcaaatgattgtgctaacttatttcccctag

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