Orcinus orca (killer whale): 101289847 Help Entry 101289847         CDS       T05247                                  Gene name CASP3 Definition (RefSeq) caspase-3   KO K02187   caspase 3 [EC:3.4.22.56] Organism oor  Orcinus orca (killer whale) Pathway oor01524   Platinum drug resistance oor04010   MAPK signaling pathway oor04115   p53 signaling pathway oor04210   Apoptosis oor04215   Apoptosis - multiple species oor04650   Natural killer cell mediated cytotoxicity oor04657   IL-17 signaling pathway oor04668   TNF signaling pathway oor04726   Serotonergic synapse oor04932   Non-alcoholic fatty liver disease oor04933   AGE-RAGE signaling pathway in diabetic complications oor05010   Alzheimer disease oor05012   Parkinson disease oor05014   Amyotrophic lateral sclerosis oor05016   Huntington disease oor05020   Prion disease oor05022   Pathways of neurodegeneration - multiple diseases oor05132   Salmonella infection oor05133   Pertussis oor05134   Legionellosis oor05145   Toxoplasmosis oor05146   Amoebiasis oor05152   Tuberculosis oor05160   Hepatitis C oor05161   Hepatitis B oor05162   Measles oor05163   Human cytomegalovirus infection oor05164   Influenza A oor05165   Human papillomavirus infection oor05167   Kaposi sarcoma-associated herpesvirus infection oor05168   Herpes simplex virus 1 infection oor05169   Epstein-Barr virus infection oor05170   Human immunodeficiency virus 1 infection oor05200   Pathways in cancer oor05203   Viral carcinogenesis oor05205   Proteoglycans in cancer oor05206   MicroRNAs in cancer oor05210   Colorectal cancer oor05222   Small cell lung cancer oor05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:oor00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101289847 (CASP3)    04668 TNF signaling pathway     101289847 (CASP3)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     101289847 (CASP3)    04215 Apoptosis - multiple species     101289847 (CASP3)    04115 p53 signaling pathway     101289847 (CASP3)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     101289847 (CASP3)    04657 IL-17 signaling pathway     101289847 (CASP3)   09156 Nervous system    04726 Serotonergic synapse     101289847 (CASP3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101289847 (CASP3)    05206 MicroRNAs in cancer     101289847 (CASP3)    05205 Proteoglycans in cancer     101289847 (CASP3)    05203 Viral carcinogenesis     101289847 (CASP3)   09162 Cancer: specific types    05210 Colorectal cancer     101289847 (CASP3)    05222 Small cell lung cancer     101289847 (CASP3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     101289847 (CASP3)    05161 Hepatitis B     101289847 (CASP3)    05160 Hepatitis C     101289847 (CASP3)    05164 Influenza A     101289847 (CASP3)    05162 Measles     101289847 (CASP3)    05168 Herpes simplex virus 1 infection     101289847 (CASP3)    05163 Human cytomegalovirus infection     101289847 (CASP3)    05167 Kaposi sarcoma-associated herpesvirus infection     101289847 (CASP3)    05169 Epstein-Barr virus infection     101289847 (CASP3)    05165 Human papillomavirus infection     101289847 (CASP3)   09171 Infectious disease: bacterial    05132 Salmonella infection     101289847 (CASP3)    05133 Pertussis     101289847 (CASP3)    05134 Legionellosis     101289847 (CASP3)    05152 Tuberculosis     101289847 (CASP3)   09174 Infectious disease: parasitic    05146 Amoebiasis     101289847 (CASP3)    05145 Toxoplasmosis     101289847 (CASP3)   09164 Neurodegenerative disease    05010 Alzheimer disease     101289847 (CASP3)    05012 Parkinson disease     101289847 (CASP3)    05014 Amyotrophic lateral sclerosis     101289847 (CASP3)    05016 Huntington disease     101289847 (CASP3)    05020 Prion disease     101289847 (CASP3)    05022 Pathways of neurodegeneration - multiple diseases     101289847 (CASP3)   09166 Cardiovascular disease    05416 Viral myocarditis     101289847 (CASP3)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     101289847 (CASP3)    04933 AGE-RAGE signaling pathway in diabetic complications     101289847 (CASP3)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     101289847 (CASP3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:oor01002]     101289847 (CASP3) Enzymes [BR:oor01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.56  caspase-3      101289847 (CASP3) Peptidases and inhibitors [BR:oor01002]  Cysteine peptidases   Family C14: caspase family    101289847 (CASP3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 SICA_beta Motif Other DBs NCBI-GeneID:  101289847 NCBI-ProteinID:  XP_004281784 LinkDB All DBs Position Unknown AA seq 275 aa AA seqDB search MENNENSVDSKSIKTSETKILHGSKSMDSGISLDYSYKMDYPEMGLCIIINNKNFHESTG MACRSGTDVDAANLWETFTNLKYEVRNKNDLTCEEILELMYNVSKEDHSKRSSFICVLLS HGEEGKIFGTNGPVDLKKLAGFFRGDCCISLTGKPKLFVIQACRGTELDCGIETDSGVED DMACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYAHKLELMHILTRVN RKVAIEFESFSNDSTFHAKKQIPCIVSMLTKELYF NT seq 828 nt NT seq  +upstreamnt  +downstreamnt atggagaacaatgaaaattcagtggattcaaaatccattaaaacttcagagacaaagatc ttacatggaagcaaatcaatggactctggaatatccttggactatagttacaaaatggat tatcctgaaatgggtttatgtataataattaataataagaactttcatgaaagtactggg atggcatgtcggtctggtacagacgtagatgcagcaaacctctgggaaaccttcacgaac ttgaaatatgaagttaggaataaaaatgatcttacatgtgaagaaattttggaattaatg tacaatgtttctaaagaagatcacagcaaaaggagcagttttatttgcgtgcttctaagc catggcgaggaaggaaaaatttttggaacaaatggacctgtcgatctgaaaaaattagca ggtttcttcagaggggattgttgtataagcctaactggcaaacctaagcttttcgttatt caggcttgccgaggcacagaactggactgtggtattgagacagacagtggtgttgaggat gacatggcctgtcagaaaataccagttgaggcagacttcttgtatgcatattctacagca cctggttactattcctggcgaaattcaaaggacggatcctggttcatccagtcactttgt gcaatgctgaaacagtacgctcacaagcttgagcttatgcatattctcactcgggttaac cgaaaggtagcaatagaattcgagtccttttccaatgattctacttttcatgcaaagaaa cagattccttgtattgtgtctatgctcacaaaagaactgtatttttaa

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