KEGG   Odobenus rosmarus divergens (Pacific walrus): 101362094
Entry
101362094         CDS       T05148                                 

Gene name
GRB2
Definition
(RefSeq) growth factor receptor-bound protein 2 isoform X1
  KO
K04364  growth factor receptor-bound protein 2
Organism
oro  Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro01521  EGFR tyrosine kinase inhibitor resistance
oro01522  Endocrine resistance
oro04010  MAPK signaling pathway
oro04012  ErbB signaling pathway
oro04014  Ras signaling pathway
oro04062  Chemokine signaling pathway
oro04068  FoxO signaling pathway
oro04072  Phospholipase D signaling pathway
oro04150  mTOR signaling pathway
oro04151  PI3K-Akt signaling pathway
oro04380  Osteoclast differentiation
oro04510  Focal adhesion
oro04540  Gap junction
oro04550  Signaling pathways regulating pluripotency of stem cells
oro04630  JAK-STAT signaling pathway
oro04650  Natural killer cell mediated cytotoxicity
oro04660  T cell receptor signaling pathway
oro04662  B cell receptor signaling pathway
oro04664  Fc epsilon RI signaling pathway
oro04714  Thermogenesis
oro04722  Neurotrophin signaling pathway
oro04910  Insulin signaling pathway
oro04912  GnRH signaling pathway
oro04915  Estrogen signaling pathway
oro04917  Prolactin signaling pathway
oro04926  Relaxin signaling pathway
oro04935  Growth hormone synthesis, secretion and action
oro05034  Alcoholism
oro05160  Hepatitis C
oro05161  Hepatitis B
oro05163  Human cytomegalovirus infection
oro05165  Human papillomavirus infection
oro05200  Pathways in cancer
oro05203  Viral carcinogenesis
oro05205  Proteoglycans in cancer
oro05206  MicroRNAs in cancer
oro05210  Colorectal cancer
oro05211  Renal cell carcinoma
oro05213  Endometrial cancer
oro05214  Glioma
oro05215  Prostate cancer
oro05220  Chronic myeloid leukemia
oro05221  Acute myeloid leukemia
oro05223  Non-small cell lung cancer
oro05224  Breast cancer
oro05225  Hepatocellular carcinoma
oro05226  Gastric cancer
oro05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:oro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101362094 (GRB2)
   04012 ErbB signaling pathway
    101362094 (GRB2)
   04014 Ras signaling pathway
    101362094 (GRB2)
   04630 JAK-STAT signaling pathway
    101362094 (GRB2)
   04068 FoxO signaling pathway
    101362094 (GRB2)
   04072 Phospholipase D signaling pathway
    101362094 (GRB2)
   04151 PI3K-Akt signaling pathway
    101362094 (GRB2)
   04150 mTOR signaling pathway
    101362094 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101362094 (GRB2)
   04540 Gap junction
    101362094 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    101362094 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    101362094 (GRB2)
   04660 T cell receptor signaling pathway
    101362094 (GRB2)
   04662 B cell receptor signaling pathway
    101362094 (GRB2)
   04664 Fc epsilon RI signaling pathway
    101362094 (GRB2)
   04062 Chemokine signaling pathway
    101362094 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    101362094 (GRB2)
   04912 GnRH signaling pathway
    101362094 (GRB2)
   04915 Estrogen signaling pathway
    101362094 (GRB2)
   04917 Prolactin signaling pathway
    101362094 (GRB2)
   04926 Relaxin signaling pathway
    101362094 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    101362094 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    101362094 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101362094 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    101362094 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101362094 (GRB2)
   05206 MicroRNAs in cancer
    101362094 (GRB2)
   05205 Proteoglycans in cancer
    101362094 (GRB2)
   05203 Viral carcinogenesis
    101362094 (GRB2)
   05231 Choline metabolism in cancer
    101362094 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101362094 (GRB2)
   05225 Hepatocellular carcinoma
    101362094 (GRB2)
   05226 Gastric cancer
    101362094 (GRB2)
   05214 Glioma
    101362094 (GRB2)
   05221 Acute myeloid leukemia
    101362094 (GRB2)
   05220 Chronic myeloid leukemia
    101362094 (GRB2)
   05211 Renal cell carcinoma
    101362094 (GRB2)
   05215 Prostate cancer
    101362094 (GRB2)
   05213 Endometrial cancer
    101362094 (GRB2)
   05224 Breast cancer
    101362094 (GRB2)
   05223 Non-small cell lung cancer
    101362094 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    101362094 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    101362094 (GRB2)
   05160 Hepatitis C
    101362094 (GRB2)
   05163 Human cytomegalovirus infection
    101362094 (GRB2)
   05165 Human papillomavirus infection
    101362094 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101362094 (GRB2)
   01522 Endocrine resistance
    101362094 (GRB2)
Membrane trafficking [BR:oro04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    101362094 (GRB2)
Domain-containing proteins not elsewhere classified [BR:oro04990]
 Src homology (SH) domain-containing proteins
  Signal transducing adaptor proteins
   101362094 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH2_2 SH3_3 DUF5093 hSH3 SH3_4
Other DBs
NCBI-GeneID: 101362094
NCBI-ProteinID: XP_004394397
UniProt: A0A2U3VHU3
LinkDB
Position
Unknown
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagctactgctgacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgatcagaactggtacaaggcagaa
ctcaatgggaaagatggcttcattcccaagaattacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcatgac
ggggcctttcttatccgagagagtgagagcgccccgggggacttctccctgtctgtcaag
ttcggaaatgatgtgcagcacttcaaggtgctccgagatggagctggaaagtatttcctc
tgggtggtgaaattcaattctctgaatgagctggtagattatcacaggtctacatctgtc
tccagaaaccagcagatattcctccgggacatagaacaggtgccacagcagccgacgtac
gtccaggccctctttgactttgatcctcaggaggatggagagctgggattccgtcgggga
gactttatccacgtcatggataactcagaccccaactggtggaaaggggcctgccacggg
cagaccggcatgtttccccgcaattacgtcacccctgtgaaccggaacgtctaa

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