KEGG   Odobenus rosmarus divergens (Pacific walrus): 101363525
Entry
101363525         CDS       T05148                                 

Gene name
NRAS
Definition
(RefSeq) GTPase NRas
  KO
K07828  GTPase NRas
Organism
oro  Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro01521  EGFR tyrosine kinase inhibitor resistance
oro01522  Endocrine resistance
oro04010  MAPK signaling pathway
oro04012  ErbB signaling pathway
oro04014  Ras signaling pathway
oro04015  Rap1 signaling pathway
oro04062  Chemokine signaling pathway
oro04068  FoxO signaling pathway
oro04071  Sphingolipid signaling pathway
oro04072  Phospholipase D signaling pathway
oro04137  Mitophagy - animal
oro04140  Autophagy - animal
oro04150  mTOR signaling pathway
oro04151  PI3K-Akt signaling pathway
oro04210  Apoptosis
oro04211  Longevity regulating pathway
oro04213  Longevity regulating pathway - multiple species
oro04218  Cellular senescence
oro04360  Axon guidance
oro04370  VEGF signaling pathway
oro04371  Apelin signaling pathway
oro04540  Gap junction
oro04550  Signaling pathways regulating pluripotency of stem cells
oro04625  C-type lectin receptor signaling pathway
oro04650  Natural killer cell mediated cytotoxicity
oro04660  T cell receptor signaling pathway
oro04662  B cell receptor signaling pathway
oro04664  Fc epsilon RI signaling pathway
oro04714  Thermogenesis
oro04720  Long-term potentiation
oro04722  Neurotrophin signaling pathway
oro04725  Cholinergic synapse
oro04726  Serotonergic synapse
oro04730  Long-term depression
oro04810  Regulation of actin cytoskeleton
oro04910  Insulin signaling pathway
oro04912  GnRH signaling pathway
oro04915  Estrogen signaling pathway
oro04916  Melanogenesis
oro04917  Prolactin signaling pathway
oro04919  Thyroid hormone signaling pathway
oro04921  Oxytocin signaling pathway
oro04926  Relaxin signaling pathway
oro04929  GnRH secretion
oro04933  AGE-RAGE signaling pathway in diabetic complications
oro04935  Growth hormone synthesis, secretion and action
oro05010  Alzheimer disease
oro05022  Pathways of neurodegeneration - multiple diseases
oro05034  Alcoholism
oro05160  Hepatitis C
oro05161  Hepatitis B
oro05163  Human cytomegalovirus infection
oro05165  Human papillomavirus infection
oro05166  Human T-cell leukemia virus 1 infection
oro05167  Kaposi sarcoma-associated herpesvirus infection
oro05170  Human immunodeficiency virus 1 infection
oro05200  Pathways in cancer
oro05203  Viral carcinogenesis
oro05205  Proteoglycans in cancer
oro05206  MicroRNAs in cancer
oro05210  Colorectal cancer
oro05211  Renal cell carcinoma
oro05213  Endometrial cancer
oro05214  Glioma
oro05215  Prostate cancer
oro05216  Thyroid cancer
oro05218  Melanoma
oro05219  Bladder cancer
oro05220  Chronic myeloid leukemia
oro05221  Acute myeloid leukemia
oro05223  Non-small cell lung cancer
oro05224  Breast cancer
oro05225  Hepatocellular carcinoma
oro05226  Gastric cancer
oro05230  Central carbon metabolism in cancer
oro05231  Choline metabolism in cancer
oro05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:oro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101363525 (NRAS)
   04012 ErbB signaling pathway
    101363525 (NRAS)
   04014 Ras signaling pathway
    101363525 (NRAS)
   04015 Rap1 signaling pathway
    101363525 (NRAS)
   04370 VEGF signaling pathway
    101363525 (NRAS)
   04371 Apelin signaling pathway
    101363525 (NRAS)
   04068 FoxO signaling pathway
    101363525 (NRAS)
   04072 Phospholipase D signaling pathway
    101363525 (NRAS)
   04071 Sphingolipid signaling pathway
    101363525 (NRAS)
   04151 PI3K-Akt signaling pathway
    101363525 (NRAS)
   04150 mTOR signaling pathway
    101363525 (NRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101363525 (NRAS)
   04137 Mitophagy - animal
    101363525 (NRAS)
  09143 Cell growth and death
   04210 Apoptosis
    101363525 (NRAS)
   04218 Cellular senescence
    101363525 (NRAS)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    101363525 (NRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    101363525 (NRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101363525 (NRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    101363525 (NRAS)
   04650 Natural killer cell mediated cytotoxicity
    101363525 (NRAS)
   04660 T cell receptor signaling pathway
    101363525 (NRAS)
   04662 B cell receptor signaling pathway
    101363525 (NRAS)
   04664 Fc epsilon RI signaling pathway
    101363525 (NRAS)
   04062 Chemokine signaling pathway
    101363525 (NRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    101363525 (NRAS)
   04929 GnRH secretion
    101363525 (NRAS)
   04912 GnRH signaling pathway
    101363525 (NRAS)
   04915 Estrogen signaling pathway
    101363525 (NRAS)
   04917 Prolactin signaling pathway
    101363525 (NRAS)
   04921 Oxytocin signaling pathway
    101363525 (NRAS)
   04926 Relaxin signaling pathway
    101363525 (NRAS)
   04935 Growth hormone synthesis, secretion and action
    101363525 (NRAS)
   04919 Thyroid hormone signaling pathway
    101363525 (NRAS)
   04916 Melanogenesis
    101363525 (NRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    101363525 (NRAS)
   04726 Serotonergic synapse
    101363525 (NRAS)
   04720 Long-term potentiation
    101363525 (NRAS)
   04730 Long-term depression
    101363525 (NRAS)
   04722 Neurotrophin signaling pathway
    101363525 (NRAS)
  09158 Development and regeneration
   04360 Axon guidance
    101363525 (NRAS)
  09149 Aging
   04211 Longevity regulating pathway
    101363525 (NRAS)
   04213 Longevity regulating pathway - multiple species
    101363525 (NRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    101363525 (NRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101363525 (NRAS)
   05206 MicroRNAs in cancer
    101363525 (NRAS)
   05205 Proteoglycans in cancer
    101363525 (NRAS)
   05203 Viral carcinogenesis
    101363525 (NRAS)
   05230 Central carbon metabolism in cancer
    101363525 (NRAS)
   05231 Choline metabolism in cancer
    101363525 (NRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101363525 (NRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101363525 (NRAS)
   05225 Hepatocellular carcinoma
    101363525 (NRAS)
   05226 Gastric cancer
    101363525 (NRAS)
   05214 Glioma
    101363525 (NRAS)
   05216 Thyroid cancer
    101363525 (NRAS)
   05221 Acute myeloid leukemia
    101363525 (NRAS)
   05220 Chronic myeloid leukemia
    101363525 (NRAS)
   05218 Melanoma
    101363525 (NRAS)
   05211 Renal cell carcinoma
    101363525 (NRAS)
   05219 Bladder cancer
    101363525 (NRAS)
   05215 Prostate cancer
    101363525 (NRAS)
   05213 Endometrial cancer
    101363525 (NRAS)
   05224 Breast cancer
    101363525 (NRAS)
   05223 Non-small cell lung cancer
    101363525 (NRAS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101363525 (NRAS)
   05022 Pathways of neurodegeneration - multiple diseases
    101363525 (NRAS)
  09165 Substance dependence
   05034 Alcoholism
    101363525 (NRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    101363525 (NRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101363525 (NRAS)
   05170 Human immunodeficiency virus 1 infection
    101363525 (NRAS)
   05161 Hepatitis B
    101363525 (NRAS)
   05160 Hepatitis C
    101363525 (NRAS)
   05163 Human cytomegalovirus infection
    101363525 (NRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101363525 (NRAS)
   05165 Human papillomavirus infection
    101363525 (NRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101363525 (NRAS)
   01522 Endocrine resistance
    101363525 (NRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:oro04131]
    101363525 (NRAS)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:oro04147]
    101363525 (NRAS)
   04031 GTP-binding proteins [BR:oro04031]
    101363525 (NRAS)
Membrane trafficking [BR:oro04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    101363525 (NRAS)
Exosome [BR:oro04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   101363525 (NRAS)
  Exosomal proteins of other body fluids (saliva and urine)
   101363525 (NRAS)
  Exosomal proteins of breast cancer cells
   101363525 (NRAS)
  Exosomal proteins of colorectal cancer cells
   101363525 (NRAS)
GTP-binding proteins [BR:oro04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    101363525 (NRAS)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 FeoB_N Septin ParA Ldh_1_N
Other DBs
NCBI-GeneID: 101363525
NCBI-ProteinID: XP_012418140
UniProt: A0A2U3ZGM5
LinkDB
Position
Unknown
AA seq 189 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL
PTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSNDDGTQG
CMGLPCVVM
NT seq 570 nt   +upstreamnt  +downstreamnt
atgactgagtacaaactggtggtggttggagcaggtggtgtcgggaaaagcgcattgaca
atccagctaatccagaaccactttgtagatgagtatgatcccaccatagaggattcttac
cgaaaacaggtggttatagacggtgaaacctgtctgttggacatactggatacagctggt
caagaggagtacagtgccatgagagaccaatacatgaggacaggcgaaggcttcctctgt
gtatttgccatcaataatagcaaatcatttgcagatattaacctctacagggaacagatt
aagcgcgtaaaagattcagatgatgtacctatggtgctagtaggaaataagtgtgatttg
ccaacaaggacagtggacacaaaacaagcccacgaactggccaagagttatgggattcca
ttcattgaaacctcagccaagaccagacagggtgtcgaagatgccttttacacactggta
agagaaatacgtcagtaccgaatgaagaaactcaacagcaatgatgatgggactcaaggt
tgtatggggttaccgtgtgtggtgatgtaa

KEGG   Odobenus rosmarus divergens (Pacific walrus): 101367134
Entry
101367134         CDS       T05148                                 

Definition
(RefSeq) GTPase HRas-like
  KO
K02833  GTPase HRas
Organism
oro  Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro01521  EGFR tyrosine kinase inhibitor resistance
oro01522  Endocrine resistance
oro04010  MAPK signaling pathway
oro04012  ErbB signaling pathway
oro04014  Ras signaling pathway
oro04015  Rap1 signaling pathway
oro04062  Chemokine signaling pathway
oro04068  FoxO signaling pathway
oro04071  Sphingolipid signaling pathway
oro04072  Phospholipase D signaling pathway
oro04137  Mitophagy - animal
oro04140  Autophagy - animal
oro04144  Endocytosis
oro04150  mTOR signaling pathway
oro04151  PI3K-Akt signaling pathway
oro04210  Apoptosis
oro04211  Longevity regulating pathway
oro04213  Longevity regulating pathway - multiple species
oro04218  Cellular senescence
oro04360  Axon guidance
oro04370  VEGF signaling pathway
oro04371  Apelin signaling pathway
oro04510  Focal adhesion
oro04540  Gap junction
oro04550  Signaling pathways regulating pluripotency of stem cells
oro04625  C-type lectin receptor signaling pathway
oro04630  JAK-STAT signaling pathway
oro04650  Natural killer cell mediated cytotoxicity
oro04660  T cell receptor signaling pathway
oro04662  B cell receptor signaling pathway
oro04664  Fc epsilon RI signaling pathway
oro04714  Thermogenesis
oro04720  Long-term potentiation
oro04722  Neurotrophin signaling pathway
oro04725  Cholinergic synapse
oro04726  Serotonergic synapse
oro04730  Long-term depression
oro04810  Regulation of actin cytoskeleton
oro04910  Insulin signaling pathway
oro04912  GnRH signaling pathway
oro04915  Estrogen signaling pathway
oro04916  Melanogenesis
oro04917  Prolactin signaling pathway
oro04919  Thyroid hormone signaling pathway
oro04921  Oxytocin signaling pathway
oro04926  Relaxin signaling pathway
oro04929  GnRH secretion
oro04933  AGE-RAGE signaling pathway in diabetic complications
oro04935  Growth hormone synthesis, secretion and action
oro05010  Alzheimer disease
oro05022  Pathways of neurodegeneration - multiple diseases
oro05034  Alcoholism
oro05132  Salmonella infection
oro05160  Hepatitis C
oro05161  Hepatitis B
oro05163  Human cytomegalovirus infection
oro05165  Human papillomavirus infection
oro05166  Human T-cell leukemia virus 1 infection
oro05167  Kaposi sarcoma-associated herpesvirus infection
oro05170  Human immunodeficiency virus 1 infection
oro05200  Pathways in cancer
oro05203  Viral carcinogenesis
oro05205  Proteoglycans in cancer
oro05206  MicroRNAs in cancer
oro05210  Colorectal cancer
oro05211  Renal cell carcinoma
oro05213  Endometrial cancer
oro05214  Glioma
oro05215  Prostate cancer
oro05216  Thyroid cancer
oro05218  Melanoma
oro05219  Bladder cancer
oro05220  Chronic myeloid leukemia
oro05221  Acute myeloid leukemia
oro05223  Non-small cell lung cancer
oro05224  Breast cancer
oro05225  Hepatocellular carcinoma
oro05226  Gastric cancer
oro05230  Central carbon metabolism in cancer
oro05231  Choline metabolism in cancer
oro05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:oro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101367134
   04012 ErbB signaling pathway
    101367134
   04014 Ras signaling pathway
    101367134
   04015 Rap1 signaling pathway
    101367134
   04370 VEGF signaling pathway
    101367134
   04371 Apelin signaling pathway
    101367134
   04630 JAK-STAT signaling pathway
    101367134
   04068 FoxO signaling pathway
    101367134
   04072 Phospholipase D signaling pathway
    101367134
   04071 Sphingolipid signaling pathway
    101367134
   04151 PI3K-Akt signaling pathway
    101367134
   04150 mTOR signaling pathway
    101367134
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    101367134
   04140 Autophagy - animal
    101367134
   04137 Mitophagy - animal
    101367134
  09143 Cell growth and death
   04210 Apoptosis
    101367134
   04218 Cellular senescence
    101367134
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101367134
   04540 Gap junction
    101367134
   04550 Signaling pathways regulating pluripotency of stem cells
    101367134
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101367134
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    101367134
   04650 Natural killer cell mediated cytotoxicity
    101367134
   04660 T cell receptor signaling pathway
    101367134
   04662 B cell receptor signaling pathway
    101367134
   04664 Fc epsilon RI signaling pathway
    101367134
   04062 Chemokine signaling pathway
    101367134
  09152 Endocrine system
   04910 Insulin signaling pathway
    101367134
   04929 GnRH secretion
    101367134
   04912 GnRH signaling pathway
    101367134
   04915 Estrogen signaling pathway
    101367134
   04917 Prolactin signaling pathway
    101367134
   04921 Oxytocin signaling pathway
    101367134
   04926 Relaxin signaling pathway
    101367134
   04935 Growth hormone synthesis, secretion and action
    101367134
   04919 Thyroid hormone signaling pathway
    101367134
   04916 Melanogenesis
    101367134
  09156 Nervous system
   04725 Cholinergic synapse
    101367134
   04726 Serotonergic synapse
    101367134
   04720 Long-term potentiation
    101367134
   04730 Long-term depression
    101367134
   04722 Neurotrophin signaling pathway
    101367134
  09158 Development and regeneration
   04360 Axon guidance
    101367134
  09149 Aging
   04211 Longevity regulating pathway
    101367134
   04213 Longevity regulating pathway - multiple species
    101367134
  09159 Environmental adaptation
   04714 Thermogenesis
    101367134
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101367134
   05206 MicroRNAs in cancer
    101367134
   05205 Proteoglycans in cancer
    101367134
   05203 Viral carcinogenesis
    101367134
   05230 Central carbon metabolism in cancer
    101367134
   05231 Choline metabolism in cancer
    101367134
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101367134
  09162 Cancer: specific types
   05210 Colorectal cancer
    101367134
   05225 Hepatocellular carcinoma
    101367134
   05226 Gastric cancer
    101367134
   05214 Glioma
    101367134
   05216 Thyroid cancer
    101367134
   05221 Acute myeloid leukemia
    101367134
   05220 Chronic myeloid leukemia
    101367134
   05218 Melanoma
    101367134
   05211 Renal cell carcinoma
    101367134
   05219 Bladder cancer
    101367134
   05215 Prostate cancer
    101367134
   05213 Endometrial cancer
    101367134
   05224 Breast cancer
    101367134
   05223 Non-small cell lung cancer
    101367134
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101367134
   05022 Pathways of neurodegeneration - multiple diseases
    101367134
  09165 Substance dependence
   05034 Alcoholism
    101367134
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    101367134
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101367134
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101367134
   05170 Human immunodeficiency virus 1 infection
    101367134
   05161 Hepatitis B
    101367134
   05160 Hepatitis C
    101367134
   05163 Human cytomegalovirus infection
    101367134
   05167 Kaposi sarcoma-associated herpesvirus infection
    101367134
   05165 Human papillomavirus infection
    101367134
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101367134
   01522 Endocrine resistance
    101367134
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:oro04131]
    101367134
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:oro04147]
    101367134
   04031 GTP-binding proteins [BR:oro04031]
    101367134
Membrane trafficking [BR:oro04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    101367134
Exosome [BR:oro04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   101367134
  Exosomal proteins of colorectal cancer cells
   101367134
GTP-binding proteins [BR:oro04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    101367134
SSDB
Motif
Pfam: Ras Roc
Other DBs
NCBI-GeneID: 101367134
NCBI-ProteinID: XP_004415431
UniProt: A0A2U3X0A7
LinkDB
Position
Unknown
AA seq 177 aa
MFWDRYGIRCGNSARTIQLIQNHVMDEHDPSMEDSNQKRVVMGGEMRLLDVLDMAGQEEN
SALRDQYVPTGQGFLCVFAITTTTSLEDIHQYREQIKGVKDSSEGSGSRSGTLRDSLGHS
RIPVTQRPTHWLEAAFQTLVREIQEHKVGRLSSPEEGGPGCRGSKSLLPVMSLPGPL
NT seq 534 nt   +upstreamnt  +downstreamnt
atgttctgggaccgctatggaatcaggtgtgggaatagtgcccggaccatccagctcatc
cagaaccacgtcatggatgagcatgaccccagcatggaagactccaatcagaagcgagtg
gttatgggtggtgagatgcgcctgctggacgttctggacatggcgggccaggaggaaaat
agcgccctgcgggaccagtacgtgcccactggacaaggcttcctgtgtgtgtttgccatc
accaccaccacgtccttggaggacatccaccagtaccgggagcagatcaagggagtgaag
gactccagtgaggggtctggctccaggtctgggactctccgggactctctgggacactcc
aggatccccgtgacccagcggcccacgcattggcttgaggctgccttccagacgctggtg
cgagagatccaggagcacaaggtgggaaggctgagctcacccgaggagggtggcccgggc
tgcaggggctccaagtccctgctccccgtgatgtcccttccaggccccctctga

KEGG   Odobenus rosmarus divergens (Pacific walrus): 101370458
Entry
101370458         CDS       T05148                                 

Gene name
KRAS
Definition
(RefSeq) GTPase KRas isoform X2
  KO
K07827  GTPase KRas
Organism
oro  Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro01521  EGFR tyrosine kinase inhibitor resistance
oro01522  Endocrine resistance
oro04010  MAPK signaling pathway
oro04012  ErbB signaling pathway
oro04014  Ras signaling pathway
oro04015  Rap1 signaling pathway
oro04062  Chemokine signaling pathway
oro04068  FoxO signaling pathway
oro04071  Sphingolipid signaling pathway
oro04072  Phospholipase D signaling pathway
oro04137  Mitophagy - animal
oro04140  Autophagy - animal
oro04150  mTOR signaling pathway
oro04151  PI3K-Akt signaling pathway
oro04210  Apoptosis
oro04211  Longevity regulating pathway
oro04213  Longevity regulating pathway - multiple species
oro04218  Cellular senescence
oro04360  Axon guidance
oro04370  VEGF signaling pathway
oro04371  Apelin signaling pathway
oro04540  Gap junction
oro04550  Signaling pathways regulating pluripotency of stem cells
oro04625  C-type lectin receptor signaling pathway
oro04650  Natural killer cell mediated cytotoxicity
oro04660  T cell receptor signaling pathway
oro04662  B cell receptor signaling pathway
oro04664  Fc epsilon RI signaling pathway
oro04714  Thermogenesis
oro04720  Long-term potentiation
oro04722  Neurotrophin signaling pathway
oro04725  Cholinergic synapse
oro04726  Serotonergic synapse
oro04730  Long-term depression
oro04810  Regulation of actin cytoskeleton
oro04910  Insulin signaling pathway
oro04912  GnRH signaling pathway
oro04914  Progesterone-mediated oocyte maturation
oro04915  Estrogen signaling pathway
oro04916  Melanogenesis
oro04917  Prolactin signaling pathway
oro04919  Thyroid hormone signaling pathway
oro04921  Oxytocin signaling pathway
oro04926  Relaxin signaling pathway
oro04929  GnRH secretion
oro04933  AGE-RAGE signaling pathway in diabetic complications
oro04935  Growth hormone synthesis, secretion and action
oro04960  Aldosterone-regulated sodium reabsorption
oro05010  Alzheimer disease
oro05022  Pathways of neurodegeneration - multiple diseases
oro05034  Alcoholism
oro05160  Hepatitis C
oro05161  Hepatitis B
oro05163  Human cytomegalovirus infection
oro05165  Human papillomavirus infection
oro05166  Human T-cell leukemia virus 1 infection
oro05167  Kaposi sarcoma-associated herpesvirus infection
oro05170  Human immunodeficiency virus 1 infection
oro05200  Pathways in cancer
oro05203  Viral carcinogenesis
oro05205  Proteoglycans in cancer
oro05206  MicroRNAs in cancer
oro05210  Colorectal cancer
oro05211  Renal cell carcinoma
oro05212  Pancreatic cancer
oro05213  Endometrial cancer
oro05214  Glioma
oro05215  Prostate cancer
oro05216  Thyroid cancer
oro05218  Melanoma
oro05219  Bladder cancer
oro05220  Chronic myeloid leukemia
oro05221  Acute myeloid leukemia
oro05223  Non-small cell lung cancer
oro05224  Breast cancer
oro05225  Hepatocellular carcinoma
oro05226  Gastric cancer
oro05230  Central carbon metabolism in cancer
oro05231  Choline metabolism in cancer
oro05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:oro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101370458 (KRAS)
   04012 ErbB signaling pathway
    101370458 (KRAS)
   04014 Ras signaling pathway
    101370458 (KRAS)
   04015 Rap1 signaling pathway
    101370458 (KRAS)
   04370 VEGF signaling pathway
    101370458 (KRAS)
   04371 Apelin signaling pathway
    101370458 (KRAS)
   04068 FoxO signaling pathway
    101370458 (KRAS)
   04072 Phospholipase D signaling pathway
    101370458 (KRAS)
   04071 Sphingolipid signaling pathway
    101370458 (KRAS)
   04151 PI3K-Akt signaling pathway
    101370458 (KRAS)
   04150 mTOR signaling pathway
    101370458 (KRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101370458 (KRAS)
   04137 Mitophagy - animal
    101370458 (KRAS)
  09143 Cell growth and death
   04210 Apoptosis
    101370458 (KRAS)
   04218 Cellular senescence
    101370458 (KRAS)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    101370458 (KRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    101370458 (KRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101370458 (KRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    101370458 (KRAS)
   04650 Natural killer cell mediated cytotoxicity
    101370458 (KRAS)
   04660 T cell receptor signaling pathway
    101370458 (KRAS)
   04662 B cell receptor signaling pathway
    101370458 (KRAS)
   04664 Fc epsilon RI signaling pathway
    101370458 (KRAS)
   04062 Chemokine signaling pathway
    101370458 (KRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    101370458 (KRAS)
   04929 GnRH secretion
    101370458 (KRAS)
   04912 GnRH signaling pathway
    101370458 (KRAS)
   04915 Estrogen signaling pathway
    101370458 (KRAS)
   04914 Progesterone-mediated oocyte maturation
    101370458 (KRAS)
   04917 Prolactin signaling pathway
    101370458 (KRAS)
   04921 Oxytocin signaling pathway
    101370458 (KRAS)
   04926 Relaxin signaling pathway
    101370458 (KRAS)
   04935 Growth hormone synthesis, secretion and action
    101370458 (KRAS)
   04919 Thyroid hormone signaling pathway
    101370458 (KRAS)
   04916 Melanogenesis
    101370458 (KRAS)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    101370458 (KRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    101370458 (KRAS)
   04726 Serotonergic synapse
    101370458 (KRAS)
   04720 Long-term potentiation
    101370458 (KRAS)
   04730 Long-term depression
    101370458 (KRAS)
   04722 Neurotrophin signaling pathway
    101370458 (KRAS)
  09158 Development and regeneration
   04360 Axon guidance
    101370458 (KRAS)
  09149 Aging
   04211 Longevity regulating pathway
    101370458 (KRAS)
   04213 Longevity regulating pathway - multiple species
    101370458 (KRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    101370458 (KRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101370458 (KRAS)
   05206 MicroRNAs in cancer
    101370458 (KRAS)
   05205 Proteoglycans in cancer
    101370458 (KRAS)
   05203 Viral carcinogenesis
    101370458 (KRAS)
   05230 Central carbon metabolism in cancer
    101370458 (KRAS)
   05231 Choline metabolism in cancer
    101370458 (KRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101370458 (KRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101370458 (KRAS)
   05212 Pancreatic cancer
    101370458 (KRAS)
   05225 Hepatocellular carcinoma
    101370458 (KRAS)
   05226 Gastric cancer
    101370458 (KRAS)
   05214 Glioma
    101370458 (KRAS)
   05216 Thyroid cancer
    101370458 (KRAS)
   05221 Acute myeloid leukemia
    101370458 (KRAS)
   05220 Chronic myeloid leukemia
    101370458 (KRAS)
   05218 Melanoma
    101370458 (KRAS)
   05211 Renal cell carcinoma
    101370458 (KRAS)
   05219 Bladder cancer
    101370458 (KRAS)
   05215 Prostate cancer
    101370458 (KRAS)
   05213 Endometrial cancer
    101370458 (KRAS)
   05224 Breast cancer
    101370458 (KRAS)
   05223 Non-small cell lung cancer
    101370458 (KRAS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101370458 (KRAS)
   05022 Pathways of neurodegeneration - multiple diseases
    101370458 (KRAS)
  09165 Substance dependence
   05034 Alcoholism
    101370458 (KRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    101370458 (KRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101370458 (KRAS)
   05170 Human immunodeficiency virus 1 infection
    101370458 (KRAS)
   05161 Hepatitis B
    101370458 (KRAS)
   05160 Hepatitis C
    101370458 (KRAS)
   05163 Human cytomegalovirus infection
    101370458 (KRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101370458 (KRAS)
   05165 Human papillomavirus infection
    101370458 (KRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101370458 (KRAS)
   01522 Endocrine resistance
    101370458 (KRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:oro04131]
    101370458 (KRAS)
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:oro04031]
    101370458 (KRAS)
Membrane trafficking [BR:oro04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    101370458 (KRAS)
GTP-binding proteins [BR:oro04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    101370458 (KRAS)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 MeaB FeoB_N G-alpha ATP_bind_1 Septin NPR1_interact AAA_25
Other DBs
NCBI-GeneID: 101370458
NCBI-ProteinID: XP_004412464
UniProt: A0A2U3WSX7
LinkDB
Position
Unknown
AA seq 188 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
PSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKK
SKTKCIIM
NT seq 567 nt   +upstreamnt  +downstreamnt
atgactgaatataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgacg
atacagctaattcagaatcactttgtggatgaatatgatcctacaatagaggattcctac
aggaaacaagtagtaattgatggagaaacctgtctcttggatattctcgacacagcaggt
caagaggagtacagtgcaatgagggaccagtacatgaggactggggagggctttctttgt
gtatttgccataaataatactaaatcttttgaagatattcaccattatagagaacaaata
aaaagagttaaagactctgaagatgtacctatggtcctagtaggaaataaatgtgatttg
ccttctagaacagtagacacaaaacaggctcaggacttagcaagaagttatggaattcct
tttattgaaacatcagcaaagacaagacagggtgttgatgatgccttctatacattagtt
cgagaaattcgaaaacataaagaaaagatgagcaaagatggtaaaaagaagaaaaagaag
tcaaagacaaagtgtataattatgtaa

KEGG   Odobenus rosmarus divergens (Pacific walrus): 101372786
Entry
101372786         CDS       T05148                                 

Gene name
HRAS
Definition
(RefSeq) GTPase HRas isoform X1
  KO
K02833  GTPase HRas
Organism
oro  Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro01521  EGFR tyrosine kinase inhibitor resistance
oro01522  Endocrine resistance
oro04010  MAPK signaling pathway
oro04012  ErbB signaling pathway
oro04014  Ras signaling pathway
oro04015  Rap1 signaling pathway
oro04062  Chemokine signaling pathway
oro04068  FoxO signaling pathway
oro04071  Sphingolipid signaling pathway
oro04072  Phospholipase D signaling pathway
oro04137  Mitophagy - animal
oro04140  Autophagy - animal
oro04144  Endocytosis
oro04150  mTOR signaling pathway
oro04151  PI3K-Akt signaling pathway
oro04210  Apoptosis
oro04211  Longevity regulating pathway
oro04213  Longevity regulating pathway - multiple species
oro04218  Cellular senescence
oro04360  Axon guidance
oro04370  VEGF signaling pathway
oro04371  Apelin signaling pathway
oro04510  Focal adhesion
oro04540  Gap junction
oro04550  Signaling pathways regulating pluripotency of stem cells
oro04625  C-type lectin receptor signaling pathway
oro04630  JAK-STAT signaling pathway
oro04650  Natural killer cell mediated cytotoxicity
oro04660  T cell receptor signaling pathway
oro04662  B cell receptor signaling pathway
oro04664  Fc epsilon RI signaling pathway
oro04714  Thermogenesis
oro04720  Long-term potentiation
oro04722  Neurotrophin signaling pathway
oro04725  Cholinergic synapse
oro04726  Serotonergic synapse
oro04730  Long-term depression
oro04810  Regulation of actin cytoskeleton
oro04910  Insulin signaling pathway
oro04912  GnRH signaling pathway
oro04915  Estrogen signaling pathway
oro04916  Melanogenesis
oro04917  Prolactin signaling pathway
oro04919  Thyroid hormone signaling pathway
oro04921  Oxytocin signaling pathway
oro04926  Relaxin signaling pathway
oro04929  GnRH secretion
oro04933  AGE-RAGE signaling pathway in diabetic complications
oro04935  Growth hormone synthesis, secretion and action
oro05010  Alzheimer disease
oro05022  Pathways of neurodegeneration - multiple diseases
oro05034  Alcoholism
oro05132  Salmonella infection
oro05160  Hepatitis C
oro05161  Hepatitis B
oro05163  Human cytomegalovirus infection
oro05165  Human papillomavirus infection
oro05166  Human T-cell leukemia virus 1 infection
oro05167  Kaposi sarcoma-associated herpesvirus infection
oro05170  Human immunodeficiency virus 1 infection
oro05200  Pathways in cancer
oro05203  Viral carcinogenesis
oro05205  Proteoglycans in cancer
oro05206  MicroRNAs in cancer
oro05210  Colorectal cancer
oro05211  Renal cell carcinoma
oro05213  Endometrial cancer
oro05214  Glioma
oro05215  Prostate cancer
oro05216  Thyroid cancer
oro05218  Melanoma
oro05219  Bladder cancer
oro05220  Chronic myeloid leukemia
oro05221  Acute myeloid leukemia
oro05223  Non-small cell lung cancer
oro05224  Breast cancer
oro05225  Hepatocellular carcinoma
oro05226  Gastric cancer
oro05230  Central carbon metabolism in cancer
oro05231  Choline metabolism in cancer
oro05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:oro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101372786 (HRAS)
   04012 ErbB signaling pathway
    101372786 (HRAS)
   04014 Ras signaling pathway
    101372786 (HRAS)
   04015 Rap1 signaling pathway
    101372786 (HRAS)
   04370 VEGF signaling pathway
    101372786 (HRAS)
   04371 Apelin signaling pathway
    101372786 (HRAS)
   04630 JAK-STAT signaling pathway
    101372786 (HRAS)
   04068 FoxO signaling pathway
    101372786 (HRAS)
   04072 Phospholipase D signaling pathway
    101372786 (HRAS)
   04071 Sphingolipid signaling pathway
    101372786 (HRAS)
   04151 PI3K-Akt signaling pathway
    101372786 (HRAS)
   04150 mTOR signaling pathway
    101372786 (HRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    101372786 (HRAS)
   04140 Autophagy - animal
    101372786 (HRAS)
   04137 Mitophagy - animal
    101372786 (HRAS)
  09143 Cell growth and death
   04210 Apoptosis
    101372786 (HRAS)
   04218 Cellular senescence
    101372786 (HRAS)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101372786 (HRAS)
   04540 Gap junction
    101372786 (HRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    101372786 (HRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101372786 (HRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    101372786 (HRAS)
   04650 Natural killer cell mediated cytotoxicity
    101372786 (HRAS)
   04660 T cell receptor signaling pathway
    101372786 (HRAS)
   04662 B cell receptor signaling pathway
    101372786 (HRAS)
   04664 Fc epsilon RI signaling pathway
    101372786 (HRAS)
   04062 Chemokine signaling pathway
    101372786 (HRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    101372786 (HRAS)
   04929 GnRH secretion
    101372786 (HRAS)
   04912 GnRH signaling pathway
    101372786 (HRAS)
   04915 Estrogen signaling pathway
    101372786 (HRAS)
   04917 Prolactin signaling pathway
    101372786 (HRAS)
   04921 Oxytocin signaling pathway
    101372786 (HRAS)
   04926 Relaxin signaling pathway
    101372786 (HRAS)
   04935 Growth hormone synthesis, secretion and action
    101372786 (HRAS)
   04919 Thyroid hormone signaling pathway
    101372786 (HRAS)
   04916 Melanogenesis
    101372786 (HRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    101372786 (HRAS)
   04726 Serotonergic synapse
    101372786 (HRAS)
   04720 Long-term potentiation
    101372786 (HRAS)
   04730 Long-term depression
    101372786 (HRAS)
   04722 Neurotrophin signaling pathway
    101372786 (HRAS)
  09158 Development and regeneration
   04360 Axon guidance
    101372786 (HRAS)
  09149 Aging
   04211 Longevity regulating pathway
    101372786 (HRAS)
   04213 Longevity regulating pathway - multiple species
    101372786 (HRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    101372786 (HRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101372786 (HRAS)
   05206 MicroRNAs in cancer
    101372786 (HRAS)
   05205 Proteoglycans in cancer
    101372786 (HRAS)
   05203 Viral carcinogenesis
    101372786 (HRAS)
   05230 Central carbon metabolism in cancer
    101372786 (HRAS)
   05231 Choline metabolism in cancer
    101372786 (HRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101372786 (HRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101372786 (HRAS)
   05225 Hepatocellular carcinoma
    101372786 (HRAS)
   05226 Gastric cancer
    101372786 (HRAS)
   05214 Glioma
    101372786 (HRAS)
   05216 Thyroid cancer
    101372786 (HRAS)
   05221 Acute myeloid leukemia
    101372786 (HRAS)
   05220 Chronic myeloid leukemia
    101372786 (HRAS)
   05218 Melanoma
    101372786 (HRAS)
   05211 Renal cell carcinoma
    101372786 (HRAS)
   05219 Bladder cancer
    101372786 (HRAS)
   05215 Prostate cancer
    101372786 (HRAS)
   05213 Endometrial cancer
    101372786 (HRAS)
   05224 Breast cancer
    101372786 (HRAS)
   05223 Non-small cell lung cancer
    101372786 (HRAS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101372786 (HRAS)
   05022 Pathways of neurodegeneration - multiple diseases
    101372786 (HRAS)
  09165 Substance dependence
   05034 Alcoholism
    101372786 (HRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    101372786 (HRAS)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101372786 (HRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101372786 (HRAS)
   05170 Human immunodeficiency virus 1 infection
    101372786 (HRAS)
   05161 Hepatitis B
    101372786 (HRAS)
   05160 Hepatitis C
    101372786 (HRAS)
   05163 Human cytomegalovirus infection
    101372786 (HRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101372786 (HRAS)
   05165 Human papillomavirus infection
    101372786 (HRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101372786 (HRAS)
   01522 Endocrine resistance
    101372786 (HRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:oro04131]
    101372786 (HRAS)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:oro04147]
    101372786 (HRAS)
   04031 GTP-binding proteins [BR:oro04031]
    101372786 (HRAS)
Membrane trafficking [BR:oro04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    101372786 (HRAS)
Exosome [BR:oro04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   101372786 (HRAS)
  Exosomal proteins of colorectal cancer cells
   101372786 (HRAS)
GTP-binding proteins [BR:oro04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    101372786 (HRAS)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 FeoB_N Gtr1_RagA ATP_bind_1 G-alpha Septin Ldh_1_N AAA_25
Other DBs
NCBI-GeneID: 101372786
NCBI-ProteinID: XP_004403818
UniProt: A0A2U3W6N2
LinkDB
Position
Unknown
AA seq 189 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL
AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKVRKLSPPDEGGPG
CMSCKCLLS
NT seq 570 nt   +upstreamnt  +downstreamnt
atgacagaatataagcttgtggtggtgggtgctggaggtgtggggaagagtgccctgacc
atccagctcatccagaaccactttgtggatgagtatgaccccaccatcgaggactcctat
cggaagcaagtggttatcgatggtgagacgtgcctgctggacattttggacacggcgggc
caggaagaatatagcgccatgcgggaccagtacatgcgcaccggagaaggcttcctgtgt
gtgtttgccatcaacaacaccaagtccttcgaggacatccaccagtaccgggagcagatc
aagcgagtgaaggactccgatgatgtgcccatggtgctggtggggaacaagtgtgacctg
gctgcccgcactgtggagtcccggcaggcgcaggaccttgcccgcagctatggcatcccc
tacattgagacgtcggccaagacgcgccagggcgtggaggatgccttctacacgctggtg
cgagagatccggcagcacaaggtgcgaaagctgagcccgcctgacgagggtggccccggc
tgcatgagctgcaagtgcctgctctcctga

DBGET integrated database retrieval system