KEGG   Odobenus rosmarus divergens (Pacific walrus): 101373095
Entry
101373095         CDS       T05148                                 

Gene name
SYK
Definition
(RefSeq) tyrosine-protein kinase SYK isoform X1
  KO
K05855  spleen tyrosine kinase [EC:2.7.10.2]
Organism
oro  Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro04064  NF-kappa B signaling pathway
oro04072  Phospholipase D signaling pathway
oro04151  PI3K-Akt signaling pathway
oro04380  Osteoclast differentiation
oro04611  Platelet activation
oro04625  C-type lectin receptor signaling pathway
oro04650  Natural killer cell mediated cytotoxicity
oro04662  B cell receptor signaling pathway
oro04664  Fc epsilon RI signaling pathway
oro04666  Fc gamma R-mediated phagocytosis
oro05152  Tuberculosis
oro05167  Kaposi sarcoma-associated herpesvirus infection
oro05168  Herpes simplex virus 1 infection
oro05169  Epstein-Barr virus infection
oro05171  Coronavirus disease - COVID-19
oro05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:oro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    101373095 (SYK)
   04072 Phospholipase D signaling pathway
    101373095 (SYK)
   04151 PI3K-Akt signaling pathway
    101373095 (SYK)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101373095 (SYK)
   04625 C-type lectin receptor signaling pathway
    101373095 (SYK)
   04650 Natural killer cell mediated cytotoxicity
    101373095 (SYK)
   04662 B cell receptor signaling pathway
    101373095 (SYK)
   04664 Fc epsilon RI signaling pathway
    101373095 (SYK)
   04666 Fc gamma R-mediated phagocytosis
    101373095 (SYK)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101373095 (SYK)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    101373095 (SYK)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    101373095 (SYK)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    101373095 (SYK)
   05168 Herpes simplex virus 1 infection
    101373095 (SYK)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101373095 (SYK)
   05169 Epstein-Barr virus infection
    101373095 (SYK)
Enzymes [BR:oro01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     101373095 (SYK)
Protein kinases [BR:oro01001]
 Non-receptor tyrosine kinases
  SYK family
   101373095 (SYK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 Kdo RIO1
Other DBs
NCBI-GeneID: 101373095
NCBI-ProteinID: XP_004409899
UniProt: A0A2U3WLR1
LinkDB
Position
Unknown
AA seq 635 aa
MAGSMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKA
HHYTIEREMNGTYAIAGGRTHGSPAELCHYHSQESDGLVCLLKKPFHRPPGVQPKTGPFE
DLKESLIRDYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRVESEQI
VMIGSKTNGKFLIRDRNDNGSYALCLLHEGKVLHYRIDKDKTGKLSIPDGKKFDTLWQLV
EHYSYKPDGLLRVLTVPCQKIGGQTGNINFGDRTPLPGGHPAMWSAGGIISRIKSYSFPK
PGHRKSSSSTGSRPENSVTFNPYEPDRGPWATDKDAQREAMPMDTEVYESPYADPEEIRP
KEVYLDRKLLTLEDSELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
GMKYLEECNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA
PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSAMLEKGERMGCPAGCPRE
MYELMKLCWTYEVEKRPGFENVELRLRNYYYDVVN
NT seq 1908 nt   +upstreamnt  +downstreamnt
atggcggggagcatggccgacagcgccaaccacctgcccttcttcttcggcaacatcacc
cgggaggaggcggaggactacctggtccaggggggcatgagcgatgggttgtacctgctg
cgtcagagccgcaattacctgggcggcttcgcgctatcggtggcgcacgggaggaaggcg
caccactacaccatcgagcgtgagatgaacggcacctacgccatcgcgggtggcaggaca
cacggcagcccggccgagctctgccactaccactcccaggagtccgacggcctcgtctgc
ctcctcaagaagcccttccaccggccgcccggggtgcagcccaagacaggcccattcgag
gacctgaaggagagcctcatcagggactacgtgaagcagacctggaacctgcagggtcag
gctctggagcaggccatcatcagccagaaacctcagctggagaagctgatcgccaccaca
gcccacgagaaaatgccgtggttccatgggaaaatctcacgggttgaatctgagcaaatt
gtcatgataggatccaagacaaatggaaaatttttgatcagggacaggaacgacaacggg
tcttacgccctgtgcttgctgcatgaggggaaggtgctgcactaccgcatcgataaggac
aaaaccgggaagctctccatccccgacgggaagaagttcgacacgctctggcagctagtg
gagcattactcttacaaaccagatgggctgttaagagttcttacagttccatgccagaaa
attggcgggcagacaggaaacatcaactttggagaccgcacgcccctcccagggggccat
cctgcgatgtggtcagcgggtggaataatctccagaatcaaatcatactcctttccaaag
cccggccacagaaagtcctcctcatccacagggagccggcccgagaactccgtgaccttc
aatccttacgagccagaccgggggccctgggccacagacaaagacgcccagagagaagcc
atgcccatggacaccgaagtgtacgaaagcccctatgctgaccccgaggagatcaggccc
aaggaggtctacctagaccgcaagctgctgaccctggaggacagtgagctgggctctggc
aacttcgggaccgtgaagaagggctactaccagatgaaaaaagttgtgaagacagtggct
gtgaagattctgaagaacgaggctaatgacccggctcttaaagatgagttattagcagaa
gcgaatgtcatgcagcagctcgataacccttacatcgtgcgcatgatcgggatatgtgaa
gccgagtcctggatgctggttatggagatggcagaactgggtccactcaataaatattta
cagcagaacaggcacgttaaggataagaacatcatagagctggtccatcaggtttctatg
ggaatgaaatatctggaggagtgcaattttgtgcacagagatctggctgcaagaaatgta
ttgctggtcactcaacattatgccaagattagtgatttcggactttccaaagcacttcgt
gctgacgaaaactactataaggctcagacccacgggaagtggccggtgaagtggtacgct
ccagagtgcatcaactactacaagttctccagcaagagcgacgtctggagctttggggtg
ttgatgtgggaggcgttctcctacgggcagaagccctatcggggcatgaaaggcagtgaa
gtttcagctatgctggagaaaggagagaggatggggtgccccgccgggtgtccaagggag
atgtacgagctgatgaagctgtgctggacatatgaggtggagaagagacccggcttcgaa
aacgtggagctgcggctgcgcaactactactacgacgtggtgaactaa

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