KEGG   Odobenus rosmarus divergens (Pacific walrus): 101373587Help
Entry
101373587         CDS       T05148                                 

Gene name
STAT3
Definition
(RefSeq) signal transducer and activator of transcription 3 isoform X1
  KO
K04692  signal transducer and activator of transcription 3
Organism
oro  Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro01521  EGFR tyrosine kinase inhibitor resistance
oro04062  Chemokine signaling pathway
oro04066  HIF-1 signaling pathway
oro04068  FoxO signaling pathway
oro04217  Necroptosis
oro04550  Signaling pathways regulating pluripotency of stem cells
oro04630  Jak-STAT signaling pathway
oro04659  Th17 cell differentiation
oro04917  Prolactin signaling pathway
oro04920  Adipocytokine signaling pathway
oro04931  Insulin resistance
oro04933  AGE-RAGE signaling pathway in diabetic complications
oro05145  Toxoplasmosis
oro05160  Hepatitis C
oro05161  Hepatitis B
oro05162  Measles
oro05163  Human cytomegalovirus infection
oro05167  Kaposi sarcoma-associated herpesvirus infection
oro05169  Epstein-Barr virus infection
oro05200  Pathways in cancer
oro05203  Viral carcinogenesis
oro05205  Proteoglycans in cancer
oro05206  MicroRNAs in cancer
oro05212  Pancreatic cancer
oro05221  Acute myeloid leukemia
oro05223  Non-small cell lung cancer
oro05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
oro05321  Inflammatory bowel disease (IBD)
Brite
KEGG Orthology (KO) [BR:oro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 Jak-STAT signaling pathway
    101373587 (STAT3)
   04066 HIF-1 signaling pathway
    101373587 (STAT3)
   04068 FoxO signaling pathway
    101373587 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    101373587 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    101373587 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    101373587 (STAT3)
   04062 Chemokine signaling pathway
    101373587 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    101373587 (STAT3)
   04917 Prolactin signaling pathway
    101373587 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101373587 (STAT3)
   05206 MicroRNAs in cancer
    101373587 (STAT3)
   05205 Proteoglycans in cancer
    101373587 (STAT3)
   05203 Viral carcinogenesis
    101373587 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101373587 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    101373587 (STAT3)
   05221 Acute myeloid leukemia
    101373587 (STAT3)
   05223 Non-small cell lung cancer
    101373587 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease (IBD)
    101373587 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    101373587 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101373587 (STAT3)
  09172 Infectious disease: viral
   05162 Measles
    101373587 (STAT3)
   05161 Hepatitis B
    101373587 (STAT3)
   05160 Hepatitis C
    101373587 (STAT3)
   05163 Human cytomegalovirus infection
    101373587 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101373587 (STAT3)
   05169 Epstein-Barr virus infection
    101373587 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101373587 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101373587 (STAT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:oro03000]
    101373587 (STAT3)
Transcription factors [BR:oro03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    101373587 (STAT3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 Baculo_PEP_C DUF3287 Syntaxin-6_N
Motif
Other DBs
NCBI-GeneID: 101373587
NCBI-ProteinID: XP_004410592
UniProt: A0A2U3WNF0
LinkDB All DBs
Position
Unknown
AA seq 770 aa AA seqDB search
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMPDLNGNNQSVTRQKMQQLEQMLTALDQMRRNIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM
NT seq 2313 nt NT seq  +upstreamnt  +downstreamnt
atggcccaatggaatcagctacagcagctcgacacgaggtacctggagcagcttcatcag
ctgtatagtgacagcttcccgatggagctgcgacagtttctggccccttggattgagagt
caagactgggcatatgcagccagcaaagaatcacatgcgactttggtgtttcataatctc
ttgggtgagattgaccagcagtacagccgtttcctacaggagtcaaatgttctctatcag
cacaatctacggagaatcaagcagttccttcagagcagatacctggagaagccaatggag
attgcccgaatcgtggcccggtgcctgtgggaagagtcccgcctgctccaaactgcagcc
actgcggcccagcaagggggccaggccaaccaccccacagccgccgtggtgacggagaag
cagcagatgctggagcagcacctacaggatgttcggaagcgagtacaggatctagaacag
aaaatgaaagtggtcgagaatctccaggatgactttgatttcaactataaaaccctcaag
agtcaaggagacatgccggatctgaatgggaacaaccagtcagtgaccaggcagaagatg
cagcagctggagcagatgctcaccgcgctggaccagatgcggcgcaacatcgtgagtgag
ttggcggggctgttgtcagcgatggagtatgtgcagaaaacgctcaccgacgaagagctg
gctgactggaagaggcggcaacagattgcgtgcattggaggccctcccaacatctgccta
gatcgcctagaaaactggataacctcattagcagaatctcaacttcagacccgccaacaa
attaaaaaactggaggagttgcagcaaaaagtgtcctacaaaggggatcccattgtacag
caccggccaatgctggaggagaggattgtagagctgtttagaaacttaatgaaaagtgcc
ttcgtggtggagcggcagccctgcatgcccatgcatcccgaccggccgttagtcatcaag
actggagtccagttcactaccaaagtcagattgctggtcaaattccccgagttaaattat
cagcttaaaattaaagtgtgcattgacaaagactccggggatgttgcagctctcagagga
tcccggaaatttaacattctgggcacaaacacgaaagtgatgaacatggaagagtccaac
aacggcagcctgtctgcagaattcaaacacctgaccctgagagagcaaagatgtggtaat
gggggccgagccaattgtgacgcctccctgattgtcaccgaggagctgcacctgatcacc
tttgagactgaggtgtatcaccaaggcctcaagattgaccttgagacccactccttgcca
gttgtggtgatctccaacatctgtcagatgccaaatgcctgggcatcaattctgtggtat
aacatgctgaccaacaaccccaagaacgtgaactttttcaccaagcccccgattggcacc
tgggatcaagtggccgaggtgctgagctggcagttctcctccaccacaaagcgagggctg
agcatcgagcagttgactacgctggcagagaaactcttaggacctggtgtgaactattca
gggtgtcagattacgtgggctaaattttgcaaagaaaacatggctggcaaaggcttctcc
ttctgggtttggctagacaatatcattgaccttgtgaaaaagtacatcctggctctttgg
aatgaagggtacataatgggttttatcagtaaggaacgggagcgggccatcttgagcacc
aagcccccaggcacctttctgctacgattcagtgagagcagcaaagaaggaggtgtcacc
ttcacttgggtggagaaggacatcagcggtaagacccagatccagtcagtggaaccatat
accaagcagcagctgaacaacatgtcgtttgctgaaatcatcatgggctataagatcatg
gatgctaccaacatcctggtgtctccgctggtctatctctaccctgacattcctaaggag
gaggcatttggaaagtactgtagaccagagagccaggagcatcctgaagctgacccaggt
agtgctgccccatacctgaagaccaagtttatctgtgtgacaccaacgacgtgcagcaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataat
ggtgaaggtgctgagccctcagcaggagggcagttcgagtccctcacgttcgacatggag
ttgacctcagagtgcgctacctccccgatgtga

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