Odobenus rosmarus divergens (Pacific walrus): 101384711
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Entry
101384711 CDS
T05148
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
oro
Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro00010
Glycolysis / Gluconeogenesis
oro00020
Citrate cycle (TCA cycle)
oro00620
Pyruvate metabolism
oro00785
Lipoic acid metabolism
oro01100
Metabolic pathways
oro01200
Carbon metabolism
oro01210
2-Oxocarboxylic acid metabolism
oro04066
HIF-1 signaling pathway
oro04922
Glucagon signaling pathway
oro05230
Central carbon metabolism in cancer
oro05415
Diabetic cardiomyopathy
Module
oro_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
oro00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
101384711 (PDHA1)
00020 Citrate cycle (TCA cycle)
101384711 (PDHA1)
00620 Pyruvate metabolism
101384711 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
101384711 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
101384711 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
101384711 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
101384711 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101384711 (PDHA1)
Enzymes [BR:
oro01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
101384711 (PDHA1)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
101384711
NCBI-ProteinID:
XP_004401569
UniProt:
A0A2U3W0T1
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGVAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLRYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCVFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaaatgctcgccgctgtctctcgcgtgttgtcgggcgtcgctcagaagccggca
agcagagtgctcgtggcctcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgcgatcttcatcggctagaagagggccctcctgtcaccacagtgctcaccagggaggac
gggctcaggtactacaggatgatgcagactgttcgccggatggagttaaaggcagatcag
ctgtataaacagaaaatcattcgcggtttctgtcacttgtgtgatggtcaggaagcttgt
tgtgtgggcctggaggccggcataaatcccacagaccatcttatcacagcctatcgggct
catggctttacctttacccgtggactttctgtccgagaaattctcgcagagcttacagga
cgaagaggaggctgtgctaaaggaaaaggtggatcgatgcatatgtatgccaagaacttc
tacgggggcaatggcatcgttggagctcaggtgcccctgggagcagggattgcgctggcc
tgtaagtacaacggaaaggacgaggtctgcttgactctgtatggcgacggtgctgccaat
cagggtcagatatttgaagcttacaacatggcagctttgtggaaattgccgtgtgttttc
atctgtgagaataaccgctatggaatgggaacgtctgttgagagagcagcggctagcacg
gattactacaagagaggcgacttcattcctgggctgagggtggatggaatggatatcttg
tgtgtccgggaggcaacaaggtttgcagctgcttactgtagatctggaaaggggcccata
ctgatggagctacagacttaccgttaccatggacacagcatgagcgaccccggcgtcagt
taccgtacacgagaagagattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggatagaatggtgaacagcaatctggccagtgttgaagaattaaaggaaattgatgtt
gaagtgaggaaagaaattgaggatgctgcccagtttgccactgctgatcctgaaccgcct
ttggaagaactaggctatcacatttacagcagcgatccaccttttgaagttcggggtgca
aatcagtggatcaagtttaagtccatcagttaa
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