Pteropus alecto (black flying fox): 102878181 Help Entry 102878181         CDS       T02993                                  Gene name CASP8 Definition (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism pale  Pteropus alecto (black flying fox) Pathway pale01524   Platinum drug resistance pale04115   p53 signaling pathway pale04210   Apoptosis pale04215   Apoptosis - multiple species pale04217   Necroptosis pale04620   Toll-like receptor signaling pathway pale04621   NOD-like receptor signaling pathway pale04622   RIG-I-like receptor signaling pathway pale04625   C-type lectin receptor signaling pathway pale04657   IL-17 signaling pathway pale04668   TNF signaling pathway pale04932   Non-alcoholic fatty liver disease pale05010   Alzheimer disease pale05016   Huntington disease pale05022   Pathways of neurodegeneration - multiple diseases pale05132   Salmonella infection pale05134   Legionellosis pale05142   Chagas disease pale05145   Toxoplasmosis pale05152   Tuberculosis pale05160   Hepatitis C pale05161   Hepatitis B pale05162   Measles pale05163   Human cytomegalovirus infection pale05164   Influenza A pale05165   Human papillomavirus infection pale05167   Kaposi sarcoma-associated herpesvirus infection pale05168   Herpes simplex virus 1 infection pale05169   Epstein-Barr virus infection pale05170   Human immunodeficiency virus 1 infection pale05200   Pathways in cancer pale05203   Viral carcinogenesis pale05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:pale00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     102878181 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     102878181 (CASP8)    04215 Apoptosis - multiple species     102878181 (CASP8)    04217 Necroptosis     102878181 (CASP8)    04115 p53 signaling pathway     102878181 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     102878181 (CASP8)    04621 NOD-like receptor signaling pathway     102878181 (CASP8)    04622 RIG-I-like receptor signaling pathway     102878181 (CASP8)    04625 C-type lectin receptor signaling pathway     102878181 (CASP8)    04657 IL-17 signaling pathway     102878181 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102878181 (CASP8)    05203 Viral carcinogenesis     102878181 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     102878181 (CASP8)    05016 Huntington disease     102878181 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     102878181 (CASP8)   09166 Cardiovascular disease    05416 Viral myocarditis     102878181 (CASP8)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     102878181 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     102878181 (CASP8)    05134 Legionellosis     102878181 (CASP8)    05152 Tuberculosis     102878181 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102878181 (CASP8)    05161 Hepatitis B     102878181 (CASP8)    05160 Hepatitis C     102878181 (CASP8)    05164 Influenza A     102878181 (CASP8)    05162 Measles     102878181 (CASP8)    05168 Herpes simplex virus 1 infection     102878181 (CASP8)    05163 Human cytomegalovirus infection     102878181 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     102878181 (CASP8)    05169 Epstein-Barr virus infection     102878181 (CASP8)    05165 Human papillomavirus infection     102878181 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     102878181 (CASP8)    05142 Chagas disease     102878181 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     102878181 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:pale01002]     102878181 (CASP8) Enzymes [BR:pale01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      102878181 (CASP8) Peptidases and inhibitors [BR:pale01002]  Cysteine peptidases   Family C14: caspase family    102878181 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED SAP18 PYRIN Motif Other DBs NCBI-GeneID:  102878181 NCBI-ProteinID:  XP_006921414 LinkDB All DBs Position Unknown AA seq 467 aa AA seqDB search MSFNSCLYDIGENLGSDELASLKFLSLDYIPQRKQEPIKDALTLFQRLQEKRMLEESNLS FLKELLFRINRLDLLVNHLGTSGEEMKKELQIPDKAQISAYRVMLFQISEDVNKPELKAF KFLLSQEIAKCKLEDDMTLLDIFIEMEKRLILGKRNLDTLKRICDQVNKSLLKKISDYEE LSRERTSSQKGSPDSNKTQLLCWIFVFQTSDKVYRMKSKPRGYCVIFNNYDFSEARKAVP KLHSIKDRNGTDLDAGALSETFKDLHFEINTFKNCTAKEICDVLKSYQSRNHNNKDCFIC CILSHGDKGIIYGCDGQEVPIYELTSYFTGSNCPSLVDKPKIFFIQACQGDNYQRGIPVE TDSEEKETYLEMDSSFQKRYIPDEADFLLGMATVNNCVSYRNPMEGTWYIQSLCQSLREK CPRGEDILTILTDVNFEVSRKDDKKNMGKQMPQPTFTLRKKLFFPLN NT seq 1404 nt NT seq  +upstreamnt  +downstreamnt atgagtttcaacagttgtctctatgatattggggaaaatctgggcagtgatgagctggcc tccctcaagttcctgagcctggactacatcccacaaaggaagcaggaacccatcaaggat gccttaacgttattccagagactccaggaaaagagaatgttggaggaaagcaacttgtcc ttcttgaaggagctgctattccgaattaatagactggatttgctggtcaaccacctaggc accagcggagaagagatgaagaaggagctgcagataccggacaaggctcagatctctgcc tacagggtcatgctttttcagatttcggaagacgtaaacaaaccggaattgaaggccttt aagtttcttttgagccaggagatcgccaaatgtaaactggaagatgacatgaccttgctt gatattttcatagagatggagaagaggcttatacttgggaaaagaaatctggacaccctg aaaagaatctgtgaccaagtcaacaagagcctgctgaagaaaatcagtgattatgaagaa ttaagcagagaacgaacctcttcacagaagggcagcccagacagcaataagacgcagctc ctgtgttggatttttgtttttcagacatcggacaaagtttaccgaatgaaaagcaagcct cgtgggtactgtgtgatatttaacaattatgattttagcgaagcacggaaggctgtgccc aaacttcacagcatcaaggatagaaatggaacagacttggatgcaggggctttgagtgaa acctttaaagaccttcattttgagataaatactttcaaaaactgcacagcaaaggaaatc tgtgatgttctgaaatcctatcaaagcagaaaccacaataacaaggactgcttcatctgt tgcatcctctcccatggagacaagggcatcatctatggctgtgatgggcaggaagtcccc atctatgagctgacttcttacttcactggttcaaattgcccttccctcgtagacaaaccg aaaatcttttttattcaggcttgtcaaggggataactaccagagaggtatacctgttgag actgactcagaagagaaggaaacctatttagaaatggattcatcgtttcagaagagatat atccctgatgaggccgactttctgctagggatggccactgtgaacaactgtgtttcctac cgaaaccccatggagggaacctggtatattcagtcactctgtcagagcctgagagaaaaa tgtcctaggggtgaagatattcttaccatcctcactgatgtgaactttgaagtgagcaga aaggatgacaagaaaaatatggggaagcagatgccacaacctaccttcaccctgagaaaa aaactctttttccctctgaattga

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