KEGG   Pteropus alecto (black flying fox): 102878181
Entry
102878181         CDS       T02993                                 

Gene name
CASP8
Definition
(RefSeq) caspase-8
  KO
K04398  caspase 8 [EC:3.4.22.61]
Organism
pale  Pteropus alecto (black flying fox)
Pathway
pale01524  Platinum drug resistance
pale04115  p53 signaling pathway
pale04210  Apoptosis
pale04215  Apoptosis - multiple species
pale04217  Necroptosis
pale04620  Toll-like receptor signaling pathway
pale04621  NOD-like receptor signaling pathway
pale04622  RIG-I-like receptor signaling pathway
pale04625  C-type lectin receptor signaling pathway
pale04657  IL-17 signaling pathway
pale04668  TNF signaling pathway
pale04932  Non-alcoholic fatty liver disease
pale05010  Alzheimer disease
pale05016  Huntington disease
pale05022  Pathways of neurodegeneration - multiple diseases
pale05132  Salmonella infection
pale05134  Legionellosis
pale05142  Chagas disease
pale05145  Toxoplasmosis
pale05152  Tuberculosis
pale05160  Hepatitis C
pale05161  Hepatitis B
pale05162  Measles
pale05163  Human cytomegalovirus infection
pale05164  Influenza A
pale05165  Human papillomavirus infection
pale05167  Kaposi sarcoma-associated herpesvirus infection
pale05168  Herpes simplex virus 1 infection
pale05169  Epstein-Barr virus infection
pale05170  Human immunodeficiency virus 1 infection
pale05200  Pathways in cancer
pale05203  Viral carcinogenesis
pale05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:pale00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    102878181 (CASP8)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    102878181 (CASP8)
   04215 Apoptosis - multiple species
    102878181 (CASP8)
   04217 Necroptosis
    102878181 (CASP8)
   04115 p53 signaling pathway
    102878181 (CASP8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102878181 (CASP8)
   04621 NOD-like receptor signaling pathway
    102878181 (CASP8)
   04622 RIG-I-like receptor signaling pathway
    102878181 (CASP8)
   04625 C-type lectin receptor signaling pathway
    102878181 (CASP8)
   04657 IL-17 signaling pathway
    102878181 (CASP8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102878181 (CASP8)
   05203 Viral carcinogenesis
    102878181 (CASP8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102878181 (CASP8)
   05016 Huntington disease
    102878181 (CASP8)
   05022 Pathways of neurodegeneration - multiple diseases
    102878181 (CASP8)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    102878181 (CASP8)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    102878181 (CASP8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102878181 (CASP8)
   05134 Legionellosis
    102878181 (CASP8)
   05152 Tuberculosis
    102878181 (CASP8)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102878181 (CASP8)
   05161 Hepatitis B
    102878181 (CASP8)
   05160 Hepatitis C
    102878181 (CASP8)
   05164 Influenza A
    102878181 (CASP8)
   05162 Measles
    102878181 (CASP8)
   05168 Herpes simplex virus 1 infection
    102878181 (CASP8)
   05163 Human cytomegalovirus infection
    102878181 (CASP8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102878181 (CASP8)
   05169 Epstein-Barr virus infection
    102878181 (CASP8)
   05165 Human papillomavirus infection
    102878181 (CASP8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102878181 (CASP8)
   05142 Chagas disease
    102878181 (CASP8)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    102878181 (CASP8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:pale01002]
    102878181 (CASP8)
Enzymes [BR:pale01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.61  caspase-8
     102878181 (CASP8)
Peptidases and inhibitors [BR:pale01002]
 Cysteine peptidases
  Family C14: caspase family
   102878181 (CASP8)
SSDB
Motif
Pfam: Peptidase_C14 DED SAP18 PYRIN
Other DBs
NCBI-GeneID: 102878181
NCBI-ProteinID: XP_006921414
LinkDB
Position
Unknown
AA seq 467 aa
MSFNSCLYDIGENLGSDELASLKFLSLDYIPQRKQEPIKDALTLFQRLQEKRMLEESNLS
FLKELLFRINRLDLLVNHLGTSGEEMKKELQIPDKAQISAYRVMLFQISEDVNKPELKAF
KFLLSQEIAKCKLEDDMTLLDIFIEMEKRLILGKRNLDTLKRICDQVNKSLLKKISDYEE
LSRERTSSQKGSPDSNKTQLLCWIFVFQTSDKVYRMKSKPRGYCVIFNNYDFSEARKAVP
KLHSIKDRNGTDLDAGALSETFKDLHFEINTFKNCTAKEICDVLKSYQSRNHNNKDCFIC
CILSHGDKGIIYGCDGQEVPIYELTSYFTGSNCPSLVDKPKIFFIQACQGDNYQRGIPVE
TDSEEKETYLEMDSSFQKRYIPDEADFLLGMATVNNCVSYRNPMEGTWYIQSLCQSLREK
CPRGEDILTILTDVNFEVSRKDDKKNMGKQMPQPTFTLRKKLFFPLN
NT seq 1404 nt   +upstreamnt  +downstreamnt
atgagtttcaacagttgtctctatgatattggggaaaatctgggcagtgatgagctggcc
tccctcaagttcctgagcctggactacatcccacaaaggaagcaggaacccatcaaggat
gccttaacgttattccagagactccaggaaaagagaatgttggaggaaagcaacttgtcc
ttcttgaaggagctgctattccgaattaatagactggatttgctggtcaaccacctaggc
accagcggagaagagatgaagaaggagctgcagataccggacaaggctcagatctctgcc
tacagggtcatgctttttcagatttcggaagacgtaaacaaaccggaattgaaggccttt
aagtttcttttgagccaggagatcgccaaatgtaaactggaagatgacatgaccttgctt
gatattttcatagagatggagaagaggcttatacttgggaaaagaaatctggacaccctg
aaaagaatctgtgaccaagtcaacaagagcctgctgaagaaaatcagtgattatgaagaa
ttaagcagagaacgaacctcttcacagaagggcagcccagacagcaataagacgcagctc
ctgtgttggatttttgtttttcagacatcggacaaagtttaccgaatgaaaagcaagcct
cgtgggtactgtgtgatatttaacaattatgattttagcgaagcacggaaggctgtgccc
aaacttcacagcatcaaggatagaaatggaacagacttggatgcaggggctttgagtgaa
acctttaaagaccttcattttgagataaatactttcaaaaactgcacagcaaaggaaatc
tgtgatgttctgaaatcctatcaaagcagaaaccacaataacaaggactgcttcatctgt
tgcatcctctcccatggagacaagggcatcatctatggctgtgatgggcaggaagtcccc
atctatgagctgacttcttacttcactggttcaaattgcccttccctcgtagacaaaccg
aaaatcttttttattcaggcttgtcaaggggataactaccagagaggtatacctgttgag
actgactcagaagagaaggaaacctatttagaaatggattcatcgtttcagaagagatat
atccctgatgaggccgactttctgctagggatggccactgtgaacaactgtgtttcctac
cgaaaccccatggagggaacctggtatattcagtcactctgtcagagcctgagagaaaaa
tgtcctaggggtgaagatattcttaccatcctcactgatgtgaactttgaagtgagcaga
aaggatgacaagaaaaatatggggaagcagatgccacaacctaccttcaccctgagaaaa
aaactctttttccctctgaattga

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