KEGG   Pteropus alecto (black flying fox): 102884374
Entry
102884374         CDS       T02993                                 

Gene name
STAT3
Definition
(RefSeq) LOW QUALITY PROTEIN: signal transducer and activator of transcription 3
  KO
K04692  signal transducer and activator of transcription 3
Organism
pale  Pteropus alecto (black flying fox)
Pathway
pale01521  EGFR tyrosine kinase inhibitor resistance
pale04062  Chemokine signaling pathway
pale04066  HIF-1 signaling pathway
pale04068  FoxO signaling pathway
pale04217  Necroptosis
pale04550  Signaling pathways regulating pluripotency of stem cells
pale04630  JAK-STAT signaling pathway
pale04659  Th17 cell differentiation
pale04917  Prolactin signaling pathway
pale04920  Adipocytokine signaling pathway
pale04931  Insulin resistance
pale04933  AGE-RAGE signaling pathway in diabetic complications
pale04935  Growth hormone synthesis, secretion and action
pale05145  Toxoplasmosis
pale05160  Hepatitis C
pale05161  Hepatitis B
pale05162  Measles
pale05163  Human cytomegalovirus infection
pale05167  Kaposi sarcoma-associated herpesvirus infection
pale05169  Epstein-Barr virus infection
pale05200  Pathways in cancer
pale05203  Viral carcinogenesis
pale05205  Proteoglycans in cancer
pale05206  MicroRNAs in cancer
pale05212  Pancreatic cancer
pale05221  Acute myeloid leukemia
pale05223  Non-small cell lung cancer
pale05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pale05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:pale00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    102884374 (STAT3)
   04066 HIF-1 signaling pathway
    102884374 (STAT3)
   04068 FoxO signaling pathway
    102884374 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    102884374 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    102884374 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    102884374 (STAT3)
   04062 Chemokine signaling pathway
    102884374 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    102884374 (STAT3)
   04917 Prolactin signaling pathway
    102884374 (STAT3)
   04935 Growth hormone synthesis, secretion and action
    102884374 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102884374 (STAT3)
   05206 MicroRNAs in cancer
    102884374 (STAT3)
   05205 Proteoglycans in cancer
    102884374 (STAT3)
   05203 Viral carcinogenesis
    102884374 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102884374 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    102884374 (STAT3)
   05221 Acute myeloid leukemia
    102884374 (STAT3)
   05223 Non-small cell lung cancer
    102884374 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    102884374 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    102884374 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102884374 (STAT3)
  09172 Infectious disease: viral
   05162 Measles
    102884374 (STAT3)
   05161 Hepatitis B
    102884374 (STAT3)
   05160 Hepatitis C
    102884374 (STAT3)
   05163 Human cytomegalovirus infection
    102884374 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102884374 (STAT3)
   05169 Epstein-Barr virus infection
    102884374 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102884374 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102884374 (STAT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:pale03000]
    102884374 (STAT3)
Transcription factors [BR:pale03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    102884374 (STAT3)
SSDB
Motif
Pfam: STAT_alpha STAT_int STAT_bind SH2 Fib_alpha E2R135 Syntaxin-6_N DUF4795
Other DBs
NCBI-GeneID: 102884374
NCBI-ProteinID: XP_015454787
LinkDB
Position
Unknown
AA seq 775 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKRXLRILSLSVIARTPHLPMHPDRPLVIKTGVQFTTKVRLLVK
FPELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLR
EQRCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAW
ASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLG
PGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERE
RAILSTKPPGTXLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEII
MGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGAAPYLKTKFICVTP
TTCSNTIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM
NT seq 2328 nt   +upstreamnt  +downstreamnt
atggcccaatggaatcagctacagcagctcgacacacgatacctggagcagcttcatcag
ctgtacagtgacagcttcccgatggagctgcggcagtttctggccccttggattgagagt
caagattgggcttatgcagccagcaaagaatcacatgccactttggtgtttcataacctc
ttgggtgagattgaccagcagtacagccgcttcctacaagagtcgaatgttctctatcag
cacaatctgcgaagaatcaagcagttccttcagagcaggtatcttgagaagccaatggag
attgcccggatcgtggcccggtgcctgtgggaagagtctcgcctcctccaaactgcagcc
actgcagcccagcaagggggccaggccaaccaccccacagctgctgtggtgacagagaag
cagcagatgctggagcagcacctacaggatgttcggaagcgagtacaggatctagaacag
aaaatgaaagtggtagagaatctccaggatgactttgatttcaactataaaaccctcaag
agtcaaggagacatgcaggatctgaacggaaacaaccagtcggtgaccaggcagaagatg
cagcagctagaacagatgctaacagcgctggaccagatgcggcgaagcatcgtgagtgag
ttggcggggcttttgtcagctatggagtatgtgcagaaaactctcacggatgaagagctg
gctgactggaagaggcggcaacagatcgcttgcattggaggccctccgaacatctgcctc
gatcgtcttgaaaactggataacctcattagcagagtctcaacttcagacccgccaacaa
attaagaaactggaggagttgcagcaaaaagtttcctacaaaggggaccccatcgtgcag
caccggccaatgctggaggagaggatcgtggagctgttcagaaacttaatgaaaaggtaa
cttagaatcctgtccctttccgtcatcgcccgcaccccccacctgcccatgcatcccgac
cggcccttagtcatcaagactggtgtccagtttactactaaagtcagattgctggtcaaa
tttcctgagttaaattatcagcttaaaattaaagtatgcattgacaaagattccggggac
gttgcagctctcagaggatctcggaaatttaacattctgggcacaaacacgaaagtgatg
aacatggaagaatccaacaatggcagcctctccgcagaattcaaacacttgaccctgaga
gagcaaagatgtggtaacggaggccgagccaactgtgacgcctccctgattgtgacagag
gagctgcacctgatcacctttgagactgaagtgtatcaccaaggcctcaagattgaccta
gagacccactccttgccagtcgtggtgatctccaacatctgtcagatgccaaatgcctgg
gcgtccatcctgtggtataacatgctgaccaacaaccccaagaacgtgaactttttcacc
aagcccccgattggaacctgggatcaagtggctgaggtgctgagctggcagttctcctcc
accacgaagcgggggctgagcatcgagcagttgactacgctggcagagaagctcctagga
cctggtgtgaactattcagggtgtcagatcacatgggcaaaattttgcaaagaaaacatg
gctggcaagggcttctccttctgggtctggctggacaatatcatcgaccttgtgaaaaag
tacatcctggccctttggaatgaaggatacataatgggcttcatcagtaaggagagggag
agagccattctgagtaccaagcccccaggcaccntcctgctgagattcagtgaaagcagc
aaagaaggaggcgtcactttcacatgggtagagaaggacatcagcggtaagacgcagatc
cagtcagtggaaccatataccaagcagcagctgaacaacatgtcatttgcggaaatcatc
atgggctataagatcatggatgccaccaatatcctagtgtcgccgctggtctatctctat
cctgacatccccaaggaggaggcattcggaaagtactgtcggccagagagccaggagcat
cctgaggctgacccaggtgctgccccctacctgaagaccaagtttatctgtgtgacacca
acgacctgcagcaataccattgacctgccgatgtccccccgcactttagattcattgatg
cagtttggaaataatggtgaaggtgctgaaccctcagcaggagggcagtttgagtccctc
acattcgacatggagctgacctcagagtgtgctacctcccccatgtga

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