KEGG   Pteropus alecto (black flying fox): 102895931
Entry
102895931         CDS       T02993                                 

Gene name
PTPN6
Definition
(RefSeq) tyrosine-protein phosphatase non-receptor type 6 isoform X2
  KO
K05697  tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
Organism
pale  Pteropus alecto (black flying fox)
Pathway
pale04520  Adherens junction
pale04630  JAK-STAT signaling pathway
pale04650  Natural killer cell mediated cytotoxicity
pale04660  T cell receptor signaling pathway
pale04662  B cell receptor signaling pathway
pale05140  Leishmaniasis
pale05205  Proteoglycans in cancer
pale05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:pale00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    102895931 (PTPN6)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    102895931 (PTPN6)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    102895931 (PTPN6)
   04660 T cell receptor signaling pathway
    102895931 (PTPN6)
   04662 B cell receptor signaling pathway
    102895931 (PTPN6)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    102895931 (PTPN6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102895931 (PTPN6)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    102895931 (PTPN6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pale01009]
    102895931 (PTPN6)
Enzymes [BR:pale01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     102895931 (PTPN6)
Protein phosphatases and associated proteins [BR:pale01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    102895931 (PTPN6)
SSDB
Motif
Pfam: Y_phosphatase SH2 DSPc Y_phosphatase3 PTPlike_phytase
Other DBs
NCBI-GeneID: 102895931
NCBI-ProteinID: XP_006914717
UniProt: L5KI40
LinkDB
Position
Unknown
AA seq 595 aa
MVRWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDF
YDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTNERWYHGHMSGGQA
ETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGERYTLGG
SETFDSLTDLVEYFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTA
KAGFWEEFESLQKQEVKNLHQRLEGQRPENKCKNRYKNILPFDHSRVILQGRDSNVPGSD
YINANYVTNQLLGPDENAKTYIASQGCLEATVNDFWQMTWQENTRVIVMTTREVEKGRNK
CVPYWPEVGTQRVYGPYTVTNCGEYDTAEYKLRTLQVSPLDNGNLVREIWHYQYLSWPDH
GVPSEPGGVLSFLDQINQRQESLPHPGPIIVHCSAGIGRTGTIIVIDMLMESISTKGLDC
DIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVMQSQKGQESEYGNIT
YPPAMKNAHAQASRTSSKHKEDVYENLHSKNKREEKVKKQRSADKDKSKGSLKRK
NT seq 1788 nt   +upstreamnt  +downstreamnt
atggtgaggtggtttcatcgagacctcagtgggctggatgcagagaccctgctcaagggc
cgaggtgtccatgggagtttcctggctcggcctagtcgcaagaaccagggtgacttctcc
ctctccgtcagggtgggggatcaggtgacccatattcggatccagaactcgggggatttc
tacgacttgtatggaggggagaagtttgcgacgcttacagagctggtggagtactacaca
cagcagcagggcgtcctacaggaccgcgatggcaccatcatccacctcaagtaccctctt
aactgctccgaccctacgaatgagaggtggtaccatggccacatgtctggggggcaggca
gagacgttgctgcaggccaagggtgagccctggacatttcttgtgcgtgagagtctcagc
caacctggagattttgtgctgtcggtgctcagtgaccagcccaaggctggcccaggctcc
ccgctcagagtcacccatatcaaggtcatgtgtgagggtgaacgctacacattaggtggt
tcggagacctttgacagcctcacagacctggtggaatatttcaagaagacagggatcgag
gaggcctcgggtgcctttgtctacctgcggcagccctactatgccacgagggtgaatgcg
gccgacattgagaatcgggtcttggaactgaacaagaagcaggagtcggaagacacagcc
aaggctggcttctgggaagagtttgagagcctgcagaagcaggaggtgaagaacctgcac
cagcgactggaagggcagcggccagagaacaagtgcaagaaccgctataagaacatcctc
ccgttcgaccacagccgagtgatcctgcagggacgtgacagcaacgtccctgggtccgac
tacatcaacgccaactacgtcacgaaccagctgctgggccctgatgagaatgctaagacc
tacatcgccagccagggctgcctggaggccacggtcaacgacttctggcagatgacatgg
caggagaacacccgtgtcattgtcatgaccacccgagaagtggagaaaggccggaacaaa
tgtgtcccatactggccggaggtgggcactcagcgcgtgtatggaccctacactgtaacc
aactgtggggaatatgacacagccgagtacaaactccgcaccttacaggtctccccactg
gacaatggcaacctagtacgggagatctggcactaccagtacttgagctggcctgaccat
ggggtccccagtgaacctgggggcgtcctcagcttcctagaccagatcaatcagcgtcag
gaaagtctgcctcaccctgggcccatcatcgtgcattgcagcgcgggcattggccgcaca
ggcaccatcattgtcattgacatgctcatggagagcatctccactaaggggctggactgt
gacattgacatccagaagacgatccagatggtgcgggctcaacgctcgggcatggtgcag
acagaggcgcagtacaagttcatctatgtggccattgcccagtttattgaaaccaccaag
aagaagctggaggtcatgcagtcccagaagggccaagagtcagagtatgggaacatcacc
taccctccggctatgaagaatgcccatgcccaggcctcccgcacgtcctctaaacacaaa
gaggatgtgtacgagaacctgcacagtaagaacaagagggaggagaaggtgaagaaacag
cggtcagcggacaaggacaagagcaagggctccctcaagaggaagtga

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