Pteropus alecto (black flying fox): 102898762 Help Entry 102898762         CDS       T02993                                  Gene name TSC2 Definition (RefSeq) tuberin isoform X11   KO K07207   tuberous sclerosis 2 Organism pale  Pteropus alecto (black flying fox) Pathway pale04072   Phospholipase D signaling pathway pale04115   p53 signaling pathway pale04140   Autophagy - animal pale04150   mTOR signaling pathway pale04151   PI3K-Akt signaling pathway pale04152   AMPK signaling pathway pale04211   Longevity regulating pathway pale04218   Cellular senescence pale04714   Thermogenesis pale04910   Insulin signaling pathway pale04919   Thyroid hormone signaling pathway pale05163   Human cytomegalovirus infection pale05165   Human papillomavirus infection pale05168   Herpes simplex virus 1 infection pale05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:pale00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     102898762 (TSC2)    04151 PI3K-Akt signaling pathway     102898762 (TSC2)    04152 AMPK signaling pathway     102898762 (TSC2)    04150 mTOR signaling pathway     102898762 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102898762 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     102898762 (TSC2)    04218 Cellular senescence     102898762 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102898762 (TSC2)    04919 Thyroid hormone signaling pathway     102898762 (TSC2)   09149 Aging    04211 Longevity regulating pathway     102898762 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     102898762 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     102898762 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     102898762 (TSC2)    05163 Human cytomegalovirus infection     102898762 (TSC2)    05165 Human papillomavirus infection     102898762 (TSC2) Protein phosphatases and associated proteins [BR:pale01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      102898762 (TSC2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Telomere_reg-2 Cnd1 Motif Other DBs NCBI-GeneID:  102898762 NCBI-ProteinID:  XP_015446495 LinkDB All DBs Position Unknown AA seq 1623 aa AA seqDB search MDVGLSSEFLMVLVNLVKFNSCYLDEYIASMVHMICLLCVQTVSSVDIEVSLQVLDAVVC YNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYME DAPLLRGAVFFVGMALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIK KYRRELQAVTWDILLNIIERLLQQLQSLESPELRAIVHDLLTTVEELCDQNEFHGSQERY FELIESCADQRPESSLLNLITYRAQSIHPAKDGWINNLQLLMERFFRSESRSAVRIKVLD VLSFVLLINRQFYEEELINMVVISQLSHIPEDRDHQVRKLATQLLVDLAEGCHTHHFNSL LDIIEKVIARSLSPPAELEERDVAAYSASLEDVKTAVLGLLVILQTKLYALPASHAMRVY EMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADALHRLGLPTKDGVVRFSPYCLCD YMEPERGSEKKASGPLSPPTGPPGPAPVGPAVRLGSLPYSLLFRVLLQCLKQETDWKVLK LVLSKLPESLRYKVLIFTSPCSVDQLSSALCSMLSGPKTLERLRGTPEGFSRTDLHLAVV PVLTALISYHNYLDKARQREMVYCLEQGLIYRCASQCVVALAICSVEMPDIMIKALPILV VKLTHISATASMAIPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVC LAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLRSFDDTPEKDSFRARSTSLNERPKSL RIARPPKQGLNNSPPVKEFKESSAADAFRCRSISVSEHVVRSRIQTSLTSSSLGSADENS MAQADDNLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLI TVTTSVGTGTRSLLGLDSGELQGSPELSSDPSMRVRQTKEAPAKLESQAGQQVCRGARDR VRSMSGGHGLRIGALDTPASHFPGGPTLPGPQTAVVSKPEKASAGTQRPAQKEKTNLAAY VPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKERRD TALYKSLSVPAASSAKPPPPPRSNTDSAVVLEEGSPGETNLPVEPPELEDFEATLGTDRR CQHAEAYSRSSSTSSQEEKSFHAEELPAGGIPIERAGPCKAARPSVDLSFQPSQPLSKSS SSPELQTLQDILGDPGDKADVGRLSPEAKARSQSGILDGEGAAWSAPGEDSRGSAQPEGP LPSNCPRSPSGLRPRGYTISDSAPSRRGKRVERDSFKSRAGASNAEKVPGINPSFVFLQL YHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEH GSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMP TKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDYECNLVSLQ CRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRH IKRLRHRIREEAHYSNPSLPLMQMHPPGHAKAPVQAPAEPMPTYETGQRKRLISSVDDFT EFV NT seq 4872 nt NT seq  +upstreamnt  +downstreamnt atggatgttggcttgtcctcagaattccttatggtgcttgtgaacttggtcaaattcaac agctgttacctcgatgaatacatcgcatcaatggtccacatgatatgcctgctgtgtgtc cagactgtgtcttctgtggacatagaggtctctttgcaggtgctggatgctgtggtctgt tataactgcctgccagcggagagcctccccctgtttattgtcaccctctgccgcaccatc aatgtcaaggagctctgtgagccttgctggaagctgatgcgtaacctcctgggcactcac ctgggccatagtgctatctacaatatgtgccgcataatggaggacagagcctacatggaa gatgccccgctgctgagaggagctgtgttctttgttggcatggctctctggggagcccac cgactctattctctcaagaactccccgacatctgtgttgccatcgttttatgaggccatg acctgtccgaatgaggtggtgtcctatgagatcgtcctctccataaccagactcataaag aagtacaggagggagctccaggctgtgacgtgggacattctgctaaacattatcgaacgc ttgcttcagcagctccagagcctggagagcccggagctcagggccatcgtccacgaccta ctgactacggtggaagagctttgtgatcagaatgaattccacggctcacaggagagatac tttgagctcattgagagttgtgcggaccagaggcctgagtcctccctcttaaacttaata acctacagggctcagtcaatccatccggcaaaagatggctggattaacaacctgcagttg ctgatggagagattcttcaggagtgaatctcgcagtgctgtgcgcatcaaggtgctggat gttctatcctttgtgctgctcatcaacagacagttctatgaggaggagctgatcaacatg gtggtcatctcacagctctcccacatccctgaggacagagaccatcaggtccggaagctg gccacccagttgctggtggacctggctgaaggctgccacacccaccacttcaatagcctg ctggacatcattgagaaagtgatcgcccgctccctctctccacccgccgagctggaggaa agagatgtggcagcatactcagcctccttggaggatgtgaagactgccgtcctggggctc ctggtcatccttcagaccaagctgtatgccttgcctgccagccatgccatgcgtgtgtat gagatgctcgtcagccacatccagctccactacaagcacagctataccctacccattgcc agtagcattcggctgcaggcctttgacttcttgctgttgctgcgggctgatgcactacac cgccttggcctgcccacaaaggatggggttgtgcggttcagtccctactgcctctgtgac tacatggagccagagagaggctctgagaagaaggccagtggccctctgtcacctcccact ggaccacctggcccagcacccgtaggccctgctgtgcgacttggctctttgccgtactcc ctcctctttcgcgttctgctacaatgtttgaagcaggagaccgactggaaggtgctgaag cttgtgctcagcaagctgccggagtcgctgcgctacaaggtcctcatttttacctctcca tgcagcgtcgaccaactatcctccgccctctgctccatgctttcaggtcccaagaccctc gagcggctcagaggcactccggaagggttctctagaaccgacctgcatctggctgtggtt cccgtgctgacagctttgatctcttaccacaactacttggacaaagccagacagcgggaa atggtgtactgcctggagcaaggcctcatctaccgctgtgccagccagtgcgtggtggcc ctggccatctgcagcgtggagatgcctgacatcatgatcaaggccctgcccatcttggtt gtgaagctcacgcacatctcagccacggccagcatggctattccacttcttgagttcctg tcgactctggccaggttgccgcacctctacaggaactttgcagcagagcagtacgcaagc gtgtttgccatctccctgccatataccaacccctccaagttcaatcagtatattgtgtgt ctggcccatcacgtcatagctatgtggttcattaggtgccgcctgcccttccggaaagac tttgttccgtttatcactaagggcctgcgctccaacgtcctccggtcttttgatgacaca ccagagaaggacagcttcagagcgcggagcaccagtctcaacgagaggcccaagagtttg aggatagccagaccccccaaacaaggcttgaataactctccacccgtcaaagaattcaag gagagctctgcagccgatgccttccggtgccgcagcatcagtgtgtctgaacatgtggtc cgcagcaggatccagacgtcccttacaagctccagcttgggatctgcagatgagaactcg atggctcaggctgatgacaatttgaaaaatcttcacctagagctcacagaaacatgtctg gacatgatggccagatacgtgttctcaaacttcacggcagtccccaagaggtcccctgta ggagagttcctcctggccggtggcagaaccaaaacctggctggttgggaacaagcttatc accgtgacgacaagcgtggggactggaacccggtcgctgctgggtctggactcaggagag ctacagggcagcccagaattgagctctgaccccagcatgcgtgtgagacagacaaaggag gcgccagccaagctagagtcccaggctgggcagcaggtgtgccgtggggcccgggaccgg gtccgctccatgtctgggggccatggccttcgcattggtgccctggacactccagcctcc cacttcccaggaggccccactttgccaggcccacagactgcagtggtcagcaagcctgag aaggcctcagctggcacccagcgcccagcgcagaaagagaagacgaacctggcggcctac gtacccctgctgacccagggctgggcggagatcttggtccggaggcccacagggaacacc agctggctgatgagcctggagaacccgcttagccccttctcctcggacatcaacaacatg ccgctgcaggagctgtccaacgcgctcatggctgccgagcgcttcaaggagcgccgtgac acagctctgtacaagtcgctgtcagtgccggcggccagctcagccaagcctccgccaccc ccacgttctaacacagactctgcggtggttctggaggagggaagtccaggtgagactaat ttgccagtggagcccccggagttggaggacttcgaggcaacactaggcacagacagacgc tgtcagcatgctgaagcttacagcaggtcatcttcaacctccagccaggaggagaagtcg ttccacgcagaggagctgcctgctggggggatccccattgagcgagctggcccctgcaag gcagcccggccctctgtggacctctccttccagccctcgcagcccctgagcaagtccagc tcctcaccagaactgcagaccctgcaggacattcttggggaccctggggacaaggctgat gttggtcggttgagccctgaggccaaggcccggtcacagtcagggatcctagacggagaa ggtgctgcttggtcagccccaggcgaagacagccggggctctgcccagcccgagggtcct ttgccttccaactgtccccgctcccccagtggcctgcggccccgaggctacactatttct gattcagccccgtcacgcaggggcaagagggtggagagggattccttcaagagcagagct ggggcctccaatgctgagaaagtaccaggcatcaaccccagcttcgtgttcctgcagctc tatcattctcctttctttggtgacgagtccaacaagccaatccttttgcccaatgagtcc ttcgaacggtcagtgcagctccttgaccagatcccgtcatacgacacgcacaagattgcc gtcctgtacgtgggagaaggccagagcaacagtgagctcgccatcctatccaatgagcat ggctcctataggtatacggaattcctgacaggcctgggcaagctcattgagcttaaggac tgccagccagataaagtgtacctgggtggcctggatgtgtgcggcgaggatggccagttc acctactgctggcacgatgacatcatgcaagctgtctttcacatcgctaccctgatgccc accaaggacgtggacaagcaccgctgtgacaagaagcgccacctgggcaatgattttgtg tccattgtctacaacgattctggcgaggacttcaaactgggtaccatcaaaggccagttc aactttgtccatgtgattatcacccccctggactacgagtgcaacctggtgtcgctgcag tgcaggaaagacatggagggcctcgtggataccagtgtagccaagatcgtgtctgaccgc aacctgcccttcgtggcccgccagatggccctgcatgcaaatatggcctcgcaggtacac cacagccgctccaaccccactgacatctacccctccaagtggattgccaggctccgccac atcaagcgactccgtcaccggatccgtgaggaagcccactactcaaatcccagcctgccc ctgatgcagatgcaccccccaggccacgccaaagccccagtgcaggccccagccgagccc atgcccacctatgagacaggccagcggaagcgtctcatctcctccgtggatgacttcaca gagtttgtgtga

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