Pteropus alecto (black flying fox): 17963491 Help Entry 17963491          CDS       T02993                                  Symbol COX1 Name (RefSeq) cytochrome c oxidase subunit I   KO K02256   cytochrome c oxidase subunit 1 [EC:7.1.1.9] Organism pale  Pteropus alecto (black flying fox) Pathway pale00190   Oxidative phosphorylation pale01100   Metabolic pathways pale04260   Cardiac muscle contraction pale04714   Thermogenesis pale04932   Non-alcoholic fatty liver disease pale05010   Alzheimer disease pale05012   Parkinson disease pale05014   Amyotrophic lateral sclerosis pale05016   Huntington disease pale05020   Prion disease pale05022   Pathways of neurodegeneration - multiple diseases pale05208   Chemical carcinogenesis - reactive oxygen species pale05415   Diabetic cardiomyopathy Module pale_M00154   Cytochrome c oxidase Brite KEGG Orthology (KO) [BR:pale00001]  09100 Metabolism   09102 Energy metabolism    00190 Oxidative phosphorylation     17963491 (COX1)  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     17963491 (COX1)   09159 Environmental adaptation    04714 Thermogenesis     17963491 (COX1)  09160 Human Diseases   09161 Cancer: overview    05208 Chemical carcinogenesis - reactive oxygen species     17963491 (COX1)   09164 Neurodegenerative disease    05010 Alzheimer disease     17963491 (COX1)    05012 Parkinson disease     17963491 (COX1)    05014 Amyotrophic lateral sclerosis     17963491 (COX1)    05016 Huntington disease     17963491 (COX1)    05020 Prion disease     17963491 (COX1)    05022 Pathways of neurodegeneration - multiple diseases     17963491 (COX1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     17963491 (COX1)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     17963491 (COX1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03029 Mitochondrial biogenesis [BR:pale03029]     17963491 (COX1) Enzymes [BR:pale01000]  7. Translocases   7.1  Catalysing the translocation of protons    7.1.1  Linked to oxidoreductase reactions     7.1.1.9  cytochrome-c oxidase      17963491 (COX1) Mitochondrial biogenesis [BR:pale03029]  Mitochondrial DNA transcription, translation, and replication factors   Mitochondrial DNA-encoded proteins    Cytochrome c oxidase     17963491 (COX1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  COX1 Motif Other DBs NCBI-GeneID:  17963491 NCBI-ProteinID:  YP_008965256 UniProt:  V5RMP5 LinkDB All DBs Position MT AA seq 514 aa AA seqDB search MFMNRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVIVTA HAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSTVEA GAGTGWTVYPPLAGNLAHAGASVDLAIFSLHLAGISSILGAINFITTIINMKPPALSQYQ TPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGH PEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVD TRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMLWALGFIFLFTVGGLTGIVLAN SSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNQTWAKIHFLIMFVG VNMTFFPQHFLGLSGMPRRYSDYPDAYTTWNTVSSMGSFISLTAVILMVFMIWEAFASKR EVSTVELTTTNLEWLHGCPPPYHTFEEPTYVNPK NT seq 1545 nt NT seq  +upstreamnt  +downstreamnt atgttcataaatcgttgactcttttcaaccaaccacaaagatattggcactctataccta ctatttggcgcctgagctggcatagttggaacagccctcagcctgctaatccgggcagaa ctgggccagccaggaactctattgggcgacgatcaaatctataacgtaatcgtgacagcc catgcatttgtaataatcttctttatggttataccaatcataattggaggcttcggaaac tggctcgtaccactaatgattggagccccggatatggcatttccccgaataaacaacatg agcttctgacttctacctccatcgttcctacttttactagcctcatcaacggtagaggcc ggtgctggaactggatgaacagtgtacccacctctagccggtaatctagcacacgccgga gcctcagtagacctagcaatcttctcgcttcacttagctggtatttcgtcaatcctaggc gctattaatttcattaccactattatcaatataaaacctccggccctatcccagtatcaa actcccctattcgtttgatccgtcctaatcacggctgtcttactccttctgtctctgcca gtactagccgccggaatcacaatactactaacagaccgtaacctaaatacaacctttttc gaccctgcaggagggggagacccaatcctgtaccagcatctgttttgattcttcggccac ccggaagtctatattcttattctaccaggtttcggaataatttcacatattgttacctat tactctggcaaaaaagagccattcggatatataggcatagtatgggccataatatcaatt ggattcctcggctttatcgtatgagcccaccacatgttcacagtaggtatagacgttgac acacgggcgtacttcacttccgcaaccataatcatcgctattccaacaggagtaaaagta tttagctgactagccaccctgcacggaggcaatatcaaatgatctccagcaatattatga gcactaggcttcatttttctatttacagttggaggcttgactggtattgtcctagccaac tcctcacttgacattgtacttcacgacacatattatgtagtagcacatttccactatgtc ctatccataggagctgtattcgctatcatgggaggattcgtccactgattcccactattt tcaggatatactctaaatcaaacctgagcaaaaatccatttccttattatatttgtaggt gtaaatataaccttcttccctcagcacttcctaggtctgtcaggcataccacgacgctac tcagactacccagacgcgtacacaacttgaaatacagtatcctccataggatcatttatc tcactaaccgcagtaatcctcatagtatttataatctgagaggccttcgcctcaaaacga gaggtgtcgaccgtagagctaactactacaaacctagagtgactacacgggtgtccccca ccataccacacgtttgaagaacctacatacgttaacccaaaataa

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