KEGG   PATHWAY: lav04714
Entry
lav04714                    Pathway                                
Name
Thermogenesis - Loxodonta africana (African savanna elephant)
Description
Thermogenesis is essential for warm-blooded animals, ensuring normal cellular and physiological function under conditions of environmental challenge. Thermogenesis in brown and beige adipose tissue is mainly controlled by norepinephrine, which is released from sympathetic nervous system in response to cold or dietary stimuli. The mitochondrial uncoupling protein 1 (UCP1) is responsible for the process whereby chemical energy is converted into heat in these adipocytes. Activation of these adipocytes leads to an increase in calorie consumption and is expected to improve overweight conditions, providing a potential strategy for treating obesity and its related metabolic disorders.
Class
Organismal Systems; Environmental adaptation
Pathway map
lav04714  Thermogenesis
lav04714

Other DBs
GO: 1990845
Organism
Loxodonta africana (African savanna elephant) [GN:lav]
Gene
100674524  ADRB3; beta-3 adrenergic receptor [KO:K04143]
100655206  guanine nucleotide-binding protein G(s) subunit alpha isoform X1 [KO:K04632]
100669226  neuroendocrine secretory protein 55-like [KO:K04632]
100671072  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
100673570  ADCY2; LOW QUALITY PROTEIN: adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
100674724  ADCY3; adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
100675525  ADCY4; adenylate cyclase type 4 [KO:K08044] [EC:4.6.1.1]
100670244  ADCY5; LOW QUALITY PROTEIN: adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
100653532  ADCY6; adenylate cyclase type 6 isoform X1 [KO:K08046] [EC:4.6.1.1]
100653771  ADCY7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
100661616  ADCY8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
100663448  ADCY9; LOW QUALITY PROTEIN: adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
100655094  ADCY10; adenylate cyclase type 10 isoform X1 [KO:K11265] [EC:4.6.1.1]
100656966  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
100674245  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
100675162  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
100653565  CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 [KO:K09048]
100673694  CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 [KO:K09048]
100666211  CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 [KO:K09048]
100670574  CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 [KO:K09048]
100677344  CREB3; cyclic AMP-responsive element-binding protein 3 isoform X1 [KO:K09048]
100675079  CREB5; cyclic AMP-responsive element-binding protein 5 isoform X1 [KO:K09047]
100673967  PRDM16; PR domain zinc finger protein 16 [KO:K22410] [EC:2.1.1.367]
100656478  ZNF516; LOW QUALITY PROTEIN: zinc finger protein 516 [KO:K22411]
100663912  KDM1A; lysine-specific histone demethylase 1A isoform X3 [KO:K11450] [EC:1.14.99.66]
100656582  UCP1; LOW QUALITY PROTEIN: mitochondrial brown fat uncoupling protein 1 [KO:K08769]
100671524  KDM3B; lysine-specific demethylase 3B isoform X1 [KO:K15601] [EC:1.14.11.65]
100654829  KDM3A; LOW QUALITY PROTEIN: lysine-specific demethylase 3A [KO:K15601] [EC:1.14.11.65]
100654830  SMARCA2; probable global transcription activator SNF2L2 isoform X2 [KO:K11647] [EC:5.6.2.-]
100659543  SMARCA4; transcription activator BRG1 isoform X1 [KO:K11647] [EC:5.6.2.-]
100674942  SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 isoform X1 [KO:K11648]
100660769  SMARCC1; SWI/SNF complex subunit SMARCC1 isoform X3 [KO:K11649]
100655517  SMARCC2; SWI/SNF complex subunit SMARCC2 [KO:K11649]
100659599  SMARCD1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [KO:K11650]
100673764  SMARCD3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 isoform X2 [KO:K11650]
100670155  SMARCD2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 [KO:K11650]
100658784  SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 isoform X1 [KO:K11651]
100670743  ACTG1; actin, cytoplasmic 2 [KO:K05692]
100654618  ACTB; actin, cytoplasmic 1 [KO:K05692]
100669389  ACTL6A; actin-like protein 6A [KO:K11340]
100658922  ACTL6B; actin-like protein 6B [KO:K11652]
100673206  AT-rich interactive domain-containing protein 1A isoform X1 [KO:K11653]
100656075  ARID1B; LOW QUALITY PROTEIN: AT-rich interactive domain-containing protein 1B [KO:K11653]
100668907  DPF3; zinc finger protein DPF3 isoform X2 [KO:K22198]
100676459  DPF1; zinc finger protein neuro-d4 [KO:K22198]
100654408  PPARG; peroxisome proliferator-activated receptor gamma isoform X1 [KO:K08530]
100658813  MAP3K5; mitogen-activated protein kinase kinase kinase 5 isoform X1 [KO:K04426] [EC:2.7.11.25]
100675607  MAP2K3; dual specificity mitogen-activated protein kinase kinase 3 isoform X1 [KO:K04432] [EC:2.7.12.2]
100673331  MAPK14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
100656926  MAPK13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
100661039  MAPK12; mitogen-activated protein kinase 12 isoform X1 [KO:K04441] [EC:2.7.11.24]
100654985  PPARGC1A; peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X2 [KO:K07202]
100657989  ATF2; cyclic AMP-dependent transcription factor ATF-2 isoform X1 [KO:K04450]
100670854  SIRT6; NAD-dependent protein deacetylase sirtuin-6 [KO:K11416] [EC:2.3.1.286]
100661893  FGF21; LOW QUALITY PROTEIN: fibroblast growth factor 21 [KO:K22429]
100675020  PLIN1; LOW QUALITY PROTEIN: perilipin-1 [KO:K08768]
100670874  LIPE; hormone-sensitive lipase [KO:K07188] [EC:3.1.1.79]
100657987  PNPLA2; patatin-like phospholipase domain-containing protein 2 [KO:K16816] [EC:3.1.1.3]
100671842  MGLL; monoglyceride lipase isoform X1 [KO:K01054] [EC:3.1.1.23]
100659413  PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X2 [KO:K07198] [EC:2.7.11.31]
100671280  PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X1 [KO:K07198] [EC:2.7.11.31]
100665273  PRKAB2; 5'-AMP-activated protein kinase subunit beta-2 isoform X1 [KO:K07199]
100676546  PRKAB1; 5'-AMP-activated protein kinase subunit beta-1 [KO:K07199]
100669727  PRKAG1; 5'-AMP-activated protein kinase subunit gamma-1 isoform X2 [KO:K07200]
100675348  PRKAG3; 5'-AMP-activated protein kinase subunit gamma-3 [KO:K07200]
100672035  PRKAG2; 5'-AMP-activated protein kinase subunit gamma-2 [KO:K07200]
100676198  GCG; glucagon [KO:K05259]
100658874  BMP8A; bone morphogenetic protein 8A [KO:K16622]
100670539  bone morphogenetic protein 8A [KO:K16622]
100671522  CNR1; cannabinoid receptor 1 isoform X2 [KO:K04277]
100660875  NPPA; natriuretic peptides A [KO:K12334]
100660583  NPPB; natriuretic peptides B [KO:K12335]
100671961  NPR1; atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
100662471  PRKG1; cGMP-dependent protein kinase 1 isoform X1 [KO:K07376] [EC:2.7.11.12]
100657163  PRKG2; cGMP-dependent protein kinase 2 [KO:K19477] [EC:2.7.11.12]
100673673  KLB; beta-klotho [KO:K22404]
100662289  FGFR1; fibroblast growth factor receptor 1 isoform X3 [KO:K04362] [EC:2.7.10.1]
100667934  FRS2; fibroblast growth factor receptor substrate 2 isoform X3 [KO:K12461]
100655474  GRB2; growth factor receptor-bound protein 2 [KO:K04364]
100657379  SOS1; LOW QUALITY PROTEIN: son of sevenless homolog 1 [KO:K03099]
100656200  SOS2; son of sevenless homolog 2 isoform X1 [KO:K03099]
100661512  KRAS; GTPase KRas isoform X2 [KO:K07827]
100659051  NRAS; GTPase NRas [KO:K07828]
100654322  RPS6KA6; ribosomal protein S6 kinase alpha-6 isoform X1 [KO:K04373] [EC:2.7.11.1]
100658801  RPS6KA2; ribosomal protein S6 kinase alpha-2 isoform X1 [KO:K04373] [EC:2.7.11.1]
100659843  RPS6KA3; ribosomal protein S6 kinase alpha-3 [KO:K04373] [EC:2.7.11.1]
100676062  RPS6KA1; LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-1 [KO:K04373] [EC:2.7.11.1]
100667008  TSC1; hamartin isoform X1 [KO:K07206]
100670924  TSC2; tuberin isoform X4 [KO:K07207]
100671462  RHEB; GTP-binding protein Rheb isoform X1 [KO:K07208]
100657753  regulatory-associated protein of mTOR isoform X1 [KO:K07204]
100660112  MTOR; LOW QUALITY PROTEIN: serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
100670071  MLST8; target of rapamycin complex subunit LST8 [KO:K08266]
100671446  AKT1S1; proline-rich AKT1 substrate 1 isoform X2 [KO:K16184]
100653946  RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1 [KO:K04688] [EC:2.7.11.1]
100671034  RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1 [KO:K04688] [EC:2.7.11.1]
100664539  RPS6; 40S ribosomal protein S6 [KO:K02991]
100670254  ACSL4; long-chain-fatty-acid--CoA ligase 4 isoform X4 [KO:K01897] [EC:6.2.1.3]
100675620  ACSL6; long-chain-fatty-acid--CoA ligase 6 isoform X2 [KO:K01897] [EC:6.2.1.3]
100656393  ACSL5; long-chain-fatty-acid--CoA ligase 5 [KO:K01897] [EC:6.2.1.3]
100675480  ACSL1; long-chain-fatty-acid--CoA ligase 1 [KO:K01897] [EC:6.2.1.3]
100657037  ACSL3; long-chain-fatty-acid--CoA ligase 3 isoform X3 [KO:K01897] [EC:6.2.1.3]
808794  ND1; NADH dehydrogenase subunit 1 [KO:K03878] [EC:7.1.1.2]
808792  ND2; NADH dehydrogenase subunit 2 [KO:K03879] [EC:7.1.1.2]
808786  ND3; NADH dehydrogenase subunit 3 [KO:K03880] [EC:7.1.1.2]
808784  ND4; NADH dehydrogenase subunit 4 [KO:K03881] [EC:7.1.1.2]
808785  ND4L; NADH dehydrogenase subunit 4L [KO:K03882] [EC:7.1.1.2]
808793  ND5; NADH dehydrogenase subunit 5 [KO:K03883] [EC:7.1.1.2]
808795  ND6; NADH dehydrogenase subunit 6 [KO:K03884] [EC:7.1.1.2]
100677530  NDUFS1; NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial isoform X1 [KO:K03934] [EC:7.1.1.2]
100654713  NDUFS2; NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial isoform X1 [KO:K03935] [EC:7.1.1.2]
100671569  NDUFS3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial isoform X1 [KO:K03936] [EC:7.1.1.2]
100665872  NDUFS4; NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial [KO:K03937]
100669401  NDUFS5; NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 [KO:K03938]
100658561  NDUFS6; NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial [KO:K03939]
100677129  NDUFS7; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial [KO:K03940] [EC:7.1.1.2]
100671885  NDUFS8; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial [KO:K03941] [EC:7.1.1.2]
100669323  NDUFV1; NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial isoform X1 [KO:K03942] [EC:7.1.1.2]
100673749  NDUFV2; NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial [KO:K03943] [EC:7.1.1.2]
100670560  NDUFV3; NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial isoform X1 [KO:K03944]
111751867  NDUFA1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 [KO:K03945]
100654461  NDUFA2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 [KO:K03946]
100661324  NDUFA3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 [KO:K03947]
100676572  NDUFA4L2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 [KO:K03948]
100669927  NDUFA4; cytochrome c oxidase subunit NDUFA4 [KO:K03948]
100668904  cytochrome c oxidase subunit NDUFA4 [KO:K03948]
100661044  NDUFA5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 [KO:K03949]
100654354  NDUFA6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 [KO:K03950]
100663654  NDUFA7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 [KO:K03951]
100675084  NDUFA8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 [KO:K03952]
100669755  NDUFA9; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial [KO:K03953]
111752617  NDUFA10; LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial [KO:K03954]
100671498  NDUFAB1; acyl carrier protein, mitochondrial [KO:K03955]
100675610  NDUFA11; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 [KO:K03956]
100661505  NDUFA12; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 [KO:K11352]
100674818  NDUFA13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 isoform X1 [KO:K11353]
100660762  NDUFB1; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [KO:K03957]
100664407  NDUFB2; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial [KO:K03958]
100661123  NDUFB3; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 isoform X3 [KO:K03959]
100674815  NDUFB4; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 [KO:K03960]
100669954  NDUFB5; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial [KO:K03961]
100661329  NDUFB6; LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 [KO:K03962]
100675297  NDUFB7; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 [KO:K03963]
100663225  NDUFB8; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial [KO:K03964]
100659326  NDUFB9; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 [KO:K03965]
100664859  NDUFB10; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 [KO:K03966]
100659182  NDUFB11; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial [KO:K11351]
100676791  NDUFC1; NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial [KO:K03967]
104846185  NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial-like [KO:K03967]
100664015  NDUFC2; NADH dehydrogenase [ubiquinone] 1 subunit C2 [KO:K03968]
100665724  NDUFAF1; complex I intermediate-associated protein 30, mitochondrial [KO:K18159]
100672314  NDUFAF2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 isoform X1 [KO:K18160]
100656680  NDUFAF3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 isoform X1 [KO:K09008]
100665463  NDUFAF4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 [KO:K18161]
100668356  NDUFAF5; arginine-hydroxylase NDUFAF5, mitochondrial isoform X1 [KO:K18162] [EC:2.1.1.-]
100667384  NDUFAF6; NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform X1 [KO:K18163]
100653954  NDUFAF7; protein arginine methyltransferase NDUFAF7, mitochondrial isoform X2 [KO:K18164]
100655385  NDUFAF8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8 [KO:K24726]
100141371  SDHA; succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial [KO:K00234] [EC:1.3.5.1]
100141376  SDHB; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial [KO:K00235] [EC:1.3.5.1]
100672637  SDHC; succinate dehydrogenase cytochrome b560 subunit, mitochondrial [KO:K00236]
100668090  SDHD; succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial [KO:K00237]
100655924  LOW QUALITY PROTEIN: succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial-like [KO:K00237]
100667241  cytochrome b-c1 complex subunit Rieske, mitochondrial [KO:K00411] [EC:7.1.1.8]
808783  CYTB; cytochrome b [KO:K00412]
100666414  LOW QUALITY PROTEIN: cytochrome c1, heme protein, mitochondrial [KO:K00413]
100674803  cytochrome b-c1 complex subunit 1, mitochondrial [KO:K00414]
100668947  cytochrome b-c1 complex subunit 2, mitochondrial [KO:K00415]
100676911  cytochrome b-c1 complex subunit 6, mitochondrial isoform X1 [KO:K00416]
100669937  cytochrome b-c1 complex subunit 7 [KO:K00417]
100662438  cytochrome b-c1 complex subunit 8 [KO:K00418]
100659857  cytochrome b-c1 complex subunit 9 isoform X2 [KO:K00419]
100666038  cytochrome b-c1 complex subunit 10 [KO:K00420]
808791  COX1; cytochrome c oxidase subunit I [KO:K02256] [EC:7.1.1.9]
808790  COX2; cytochrome c oxidase subunit II [KO:K02261]
808787  COX3; cytochrome c oxidase subunit III [KO:K02262]
100655578  cytochrome c oxidase subunit 4 isoform 1, mitochondrial [KO:K02263]
100659426  cytochrome c oxidase subunit 4 isoform 2, mitochondrial [KO:K02263]
100659010  cytochrome c oxidase subunit 5B, mitochondrial [KO:K02265]
100663363  cytochrome c oxidase subunit 6A2, mitochondrial [KO:K02266]
100674944  cytochrome c oxidase subunit 6A1, mitochondrial isoform X1 [KO:K02266]
100676021  cytochrome c oxidase subunit 6B2 [KO:K02267]
100656914  cytochrome c oxidase subunit 6B1 isoform X2 [KO:K02267]
100673278  cytochrome c oxidase subunit 6C [KO:K02268]
100659078  cytochrome c oxidase subunit 7A-related protein, mitochondrial isoform X2 [KO:K02270]
100663191  cytochrome c oxidase subunit 7A2, mitochondrial [KO:K02270]
100657307  cytochrome c oxidase subunit 7A1, mitochondrial isoform X1 [KO:K02270]
100658215  cytochrome c oxidase subunit 7B, mitochondrial [KO:K02271]
100666763  cytochrome c oxidase subunit 7B2, mitochondrial [KO:K02271]
111749980  cytochrome c oxidase subunit 7C, mitochondrial [KO:K02272]
100665257  cytochrome c oxidase subunit 8A, mitochondrial [KO:K02273]
100671416  protoheme IX farnesyltransferase, mitochondrial [KO:K02257] [EC:2.5.1.141]
100666553  cytochrome c oxidase assembly protein COX11, mitochondrial isoform X1 [KO:K02258]
100674581  cytochrome c oxidase assembly protein COX14 [KO:K18181]
100665789  cytochrome c oxidase assembly protein COX15 homolog [KO:K02259] [EC:1.17.99.9]
104845421  cytochrome c oxidase assembly protein COX16 homolog, mitochondrial [KO:K18182]
100675578  cytochrome c oxidase copper chaperone [KO:K02260]
100666473  mitochondrial inner membrane protein COX18 [KO:K17797]
100671307  cytochrome c oxidase assembly protein COX19 isoform X2 [KO:K18183]
100658964  cytochrome c oxidase protein 20 homolog [KO:K18184]
100660845  uncharacterized protein LOC100660845 [KO:K18173]
100674533  cytochrome c oxidase assembly factor 3 homolog, mitochondrial [KO:K18175]
100661201  cytochrome c oxidase assembly factor 4 homolog, mitochondrial isoform X1 [KO:K18177]
100653856  cytochrome c oxidase assembly factor 5 [KO:K18178]
100674720  LOW QUALITY PROTEIN: cytochrome c oxidase assembly factor 6 homolog [KO:K18179]
100653561  cytochrome c oxidase assembly factor 7 [KO:K18180]
100666715  ATP5F1A; ATP synthase subunit alpha, mitochondrial [KO:K02132]
100673733  ATP5F1B; ATP synthase subunit beta, mitochondrial [KO:K02133] [EC:7.1.2.2]
100655730  ATP5F1C; ATP synthase subunit gamma, mitochondrial isoform X1 [KO:K02136]
100676000  ATP5F1D; ATP synthase subunit delta, mitochondrial [KO:K02134]
100669509  ATP5F1E; ATP synthase subunit epsilon, mitochondrial [KO:K02135]
111748544  LOW QUALITY PROTEIN: ATP synthase subunit epsilon, mitochondrial-like [KO:K02135]
111749757  LOW QUALITY PROTEIN: ATP synthase subunit epsilon-like protein, mitochondrial [KO:K02135]
100670894  ATP5PO; ATP synthase subunit O, mitochondrial isoform X1 [KO:K02137]
808788  ATP6; ATP synthase F0 subunit 6 [KO:K02126]
100675936  ATP5PB; ATP synthase F(0) complex subunit B1, mitochondrial isoform X1 [KO:K02127]
100657700  ATP5MC3; ATP synthase F(0) complex subunit C3, mitochondrial [KO:K02128]
100675957  ATP5MC1; ATP synthase F(0) complex subunit C1, mitochondrial [KO:K02128]
100663668  ATP5MC2; ATP synthase F(0) complex subunit C2, mitochondrial isoform X2 [KO:K02128]
100658039  ATP5PD; ATP synthase subunit d, mitochondrial [KO:K02138]
100654312  ATP5ME; ATP synthase subunit e, mitochondrial [KO:K02129]
100662026  ATP5MF; ATP synthase subunit f, mitochondrial [KO:K02130]
100657531  ATP5PF; ATP synthase-coupling factor 6, mitochondrial [KO:K02131]
100677671  ATP5MG; ATP synthase subunit g, mitochondrial [KO:K02140]
100665512  CPT2; carnitine O-palmitoyltransferase 2, mitochondrial [KO:K08766] [EC:2.3.1.21]
100673952  SLC25A20; mitochondrial carnitine/acylcarnitine carrier protein [KO:K15109]
100673572  SLC25A29; mitochondrial basic amino acids transporter isoform X1 [KO:K15109]
100665922  CPT1A; LOW QUALITY PROTEIN: carnitine O-palmitoyltransferase 1, liver isoform [KO:K08765] [EC:2.3.1.21]
100677247  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform isoform X1 [KO:K19523] [EC:2.3.1.21]
100667001  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [KO:K19524] [EC:2.3.1.21]
Compound
C00002  ATP
C00004  NADH
C00008  ADP
C00010  CoA
C00024  Acetyl-CoA
C00040  Acyl-CoA
C00080  H+
C00116  Glycerol
C00162  Fatty acid
C00165  Diacylglycerol
C00318  L-Carnitine
C00422  Triacylglycerol
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00745  Nicotine
C00942  3',5'-Cyclic GMP
C00951  Estradiol-17beta
C01352  FADH2
C01885  1-Acylglycerol
C02301  O-Acylcarnitine
C02465  Triiodothyronine
C11695  Anandamide
C13856  2-Arachidonoylglycerol
Reference
PMID:27251423
  Authors
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Related
pathway
lav00020  Citrate cycle (TCA cycle)
lav00190  Oxidative phosphorylation
lav04010  MAPK signaling pathway
lav04022  cGMP-PKG signaling pathway
lav04024  cAMP signaling pathway
lav04150  mTOR signaling pathway
lav04923  Regulation of lipolysis in adipocytes
KO pathway
ko04714   
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