Physeter catodon (sperm whale): 102974274
Help
Entry
102974274 CDS
T06011
Gene name
ARAF
Definition
(RefSeq) serine/threonine-protein kinase A-Raf isoform X1
KO
K08845
A-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
pcad
Physeter catodon (sperm whale)
Pathway
pcad01521
EGFR tyrosine kinase inhibitor resistance
pcad01522
Endocrine resistance
pcad04010
MAPK signaling pathway
pcad04012
ErbB signaling pathway
pcad04068
FoxO signaling pathway
pcad04270
Vascular smooth muscle contraction
pcad04650
Natural killer cell mediated cytotoxicity
pcad04720
Long-term potentiation
pcad04726
Serotonergic synapse
pcad04730
Long-term depression
pcad04810
Regulation of actin cytoskeleton
pcad04910
Insulin signaling pathway
pcad04914
Progesterone-mediated oocyte maturation
pcad04928
Parathyroid hormone synthesis, secretion and action
pcad05010
Alzheimer disease
pcad05022
Pathways of neurodegeneration - multiple diseases
pcad05034
Alcoholism
pcad05160
Hepatitis C
pcad05161
Hepatitis B
pcad05200
Pathways in cancer
pcad05205
Proteoglycans in cancer
pcad05210
Colorectal cancer
pcad05211
Renal cell carcinoma
pcad05212
Pancreatic cancer
pcad05213
Endometrial cancer
pcad05214
Glioma
pcad05215
Prostate cancer
pcad05218
Melanoma
pcad05219
Bladder cancer
pcad05220
Chronic myeloid leukemia
pcad05221
Acute myeloid leukemia
pcad05223
Non-small cell lung cancer
pcad05224
Breast cancer
pcad05225
Hepatocellular carcinoma
pcad05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102974274 (ARAF)
04012 ErbB signaling pathway
102974274 (ARAF)
04068 FoxO signaling pathway
102974274 (ARAF)
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
102974274 (ARAF)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
102974274 (ARAF)
09152 Endocrine system
04910 Insulin signaling pathway
102974274 (ARAF)
04914 Progesterone-mediated oocyte maturation
102974274 (ARAF)
04928 Parathyroid hormone synthesis, secretion and action
102974274 (ARAF)
09153 Circulatory system
04270 Vascular smooth muscle contraction
102974274 (ARAF)
09156 Nervous system
04726 Serotonergic synapse
102974274 (ARAF)
04720 Long-term potentiation
102974274 (ARAF)
04730 Long-term depression
102974274 (ARAF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102974274 (ARAF)
05205 Proteoglycans in cancer
102974274 (ARAF)
09162 Cancer: specific types
05210 Colorectal cancer
102974274 (ARAF)
05212 Pancreatic cancer
102974274 (ARAF)
05225 Hepatocellular carcinoma
102974274 (ARAF)
05226 Gastric cancer
102974274 (ARAF)
05214 Glioma
102974274 (ARAF)
05221 Acute myeloid leukemia
102974274 (ARAF)
05220 Chronic myeloid leukemia
102974274 (ARAF)
05218 Melanoma
102974274 (ARAF)
05211 Renal cell carcinoma
102974274 (ARAF)
05219 Bladder cancer
102974274 (ARAF)
05215 Prostate cancer
102974274 (ARAF)
05213 Endometrial cancer
102974274 (ARAF)
05224 Breast cancer
102974274 (ARAF)
05223 Non-small cell lung cancer
102974274 (ARAF)
09164 Neurodegenerative disease
05010 Alzheimer disease
102974274 (ARAF)
05022 Pathways of neurodegeneration - multiple diseases
102974274 (ARAF)
09165 Substance dependence
05034 Alcoholism
102974274 (ARAF)
09172 Infectious disease: viral
05161 Hepatitis B
102974274 (ARAF)
05160 Hepatitis C
102974274 (ARAF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102974274 (ARAF)
01522 Endocrine resistance
102974274 (ARAF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcad01001
]
102974274 (ARAF)
Enzymes [BR:
pcad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
102974274 (ARAF)
Protein kinases [BR:
pcad01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
102974274 (ARAF)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
Pkinase_fungal
APH
TUG-UBL1
Kdo
Motif
Other DBs
NCBI-GeneID:
102974274
NCBI-ProteinID:
XP_007104243
UniProt:
A0A2Y9ELW4
LinkDB
All DBs
Position
21
AA seq
645 aa
AA seq
DB search
MPPARNRRSGLTRGAPWHLPSPTLARLDKVLGSMEPPRGPPANGAEPSRTVGTVKVYLPN
KQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCVVYRLIKGRKTVTAWDTAIAPLDGEELI
VEVLEDVPLTMHNFQVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVD
MSTNRRQFYHSVQDLSGGSRQHEAPSNRPLNEPLTPQGPSLSPASSCTQHRDPKHFPFPA
PANAPLQRIRSTSTPNVHMVSTTAPMDSGLIQLPSQSFNTDAAGNRGGGDGTPRGSPSPA
SVSSGRKSPHSKSPSEQRERKSLADDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSF
GTVFRGRWHGDVAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAII
TQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGL
TVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYE
LMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREERPLFP
QILATIELLQRSLPKIERSASEPSLHRTQADELPACLLSAARLVP
NT seq
1938 nt
NT seq
+upstream
nt +downstream
nt
atgccccccgcccggaaccggaggagtggtttgacccggggagccccatggcacctgccc
agccccaccttagcccgtcttgacaaagtcctaggctccatggagccaccaaggggcccc
cctgccaacggggctgagccgtcccggacagtgggcaccgtcaaagtgtacctgcccaac
aagcaacgcacggtggtgactgtccgggatggcatgagtgtctacgactctctagacaag
gccctcaaggtgcggggactcaatcaggattgctgtgtggtctaccggctcatcaagggg
cgaaagacagtcaccgcctgggacacagccattgccccactggatggcgaggagctcatt
gtggaggtcctcgaagacgtccccctgaccatgcacaattttcaggtacggaagacgttc
ttcagcctggccttttgtgacttctgccttaagtttctgttccatggcttccgctgccaa
acctgtggatacaagttccaccagcattgttcctccaaggtccccacagtctgtgtcgac
atgagtaccaaccgccgacagttctaccacagtgtccaagatttgtccggaggctccaga
cagcatgaggctccctcgaaccgccccctgaatgagccactcacccctcagggtcccagc
ctttcccctgccagctcctgcacccagcaccgcgaccccaagcacttccccttccctgcc
ccagccaacgcccccctccagcgcatccgctccacatctacccccaacgtccacatggtc
agcaccacagcccccatggactccggcctcatccagctcccttcccagagtttcaacact
gacgctgccgggaatagaggtggtggcgatggaaccccccgggggagccccagcccagcc
agcgtgtcctcggggaggaagtccccacattccaagtccccgtcagagcagcgggagcgg
aagtccttggccgatgacaagaagaaagtgaagaatctggggtaccgggactcgggctat
tactgggaggtgccacccagtgaggtgcagctgctgaagaggatcgggacgggctcgttt
gggaccgtgtttcgtgggcggtggcacggcgatgtggccgtgaaggtgctcaaggtggcc
caacccacagctgagcaggcccaggccttcaagaacgagatgcaggtgctcaggaagaca
cgtcacgtcaacatcttgctgttcatgggcttcatgacccggccgggatttgctatcatc
acacagtggtgcgagggctccagtctctaccaccacctgcacgtggccgacacacgcttc
gacatggtccagctcattgatgtggcccggcagactgcccagggcatggactacctccat
gccaagaacatcatccaccgagatctcaagtctaacaacatcttcctacatgaggggctc
acggtgaagatcggggacttcggcctggccacagtgaagacgcggtggagtggggcccag
cctttggagcagccctcgggctctgtgctatggatggcagctgaggtgatccgtatgcag
gacccgaacccctacagcttccagtcggatgtctacgcctatggggttgtgctctacgag
ctcatgaccggctcgctgccttacagccacattggcagccgtgaccagattatctttatg
gtgggccgtggctatctgtccccggacctcagcaaaatctccagcaactgccccaaggcc
atgaggcgcctgctgtctgactgcctcaagttccagcgggaggagcggcccctctttccc
cagatcctggccacgattgagctgctgcagcggtcactccccaagattgagcggagtgcc
tccgaaccctccttgcaccgtacccaggctgatgagttgcctgcctgcctactcagcgca
gcccgccttgtgccttag
Physeter catodon (sperm whale): 102986916
Help
Entry
102986916 CDS
T06011
Gene name
BRAF
Definition
(RefSeq) serine/threonine-protein kinase B-raf isoform X3
KO
K04365
B-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
pcad
Physeter catodon (sperm whale)
Pathway
pcad01521
EGFR tyrosine kinase inhibitor resistance
pcad01522
Endocrine resistance
pcad04010
MAPK signaling pathway
pcad04012
ErbB signaling pathway
pcad04015
Rap1 signaling pathway
pcad04024
cAMP signaling pathway
pcad04062
Chemokine signaling pathway
pcad04068
FoxO signaling pathway
pcad04150
mTOR signaling pathway
pcad04270
Vascular smooth muscle contraction
pcad04510
Focal adhesion
pcad04650
Natural killer cell mediated cytotoxicity
pcad04720
Long-term potentiation
pcad04722
Neurotrophin signaling pathway
pcad04726
Serotonergic synapse
pcad04730
Long-term depression
pcad04810
Regulation of actin cytoskeleton
pcad04910
Insulin signaling pathway
pcad04914
Progesterone-mediated oocyte maturation
pcad04928
Parathyroid hormone synthesis, secretion and action
pcad04934
Cushing syndrome
pcad05010
Alzheimer disease
pcad05022
Pathways of neurodegeneration - multiple diseases
pcad05034
Alcoholism
pcad05160
Hepatitis C
pcad05161
Hepatitis B
pcad05200
Pathways in cancer
pcad05205
Proteoglycans in cancer
pcad05210
Colorectal cancer
pcad05211
Renal cell carcinoma
pcad05212
Pancreatic cancer
pcad05213
Endometrial cancer
pcad05214
Glioma
pcad05215
Prostate cancer
pcad05216
Thyroid cancer
pcad05218
Melanoma
pcad05219
Bladder cancer
pcad05220
Chronic myeloid leukemia
pcad05221
Acute myeloid leukemia
pcad05223
Non-small cell lung cancer
pcad05224
Breast cancer
pcad05225
Hepatocellular carcinoma
pcad05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102986916 (BRAF)
04012 ErbB signaling pathway
102986916 (BRAF)
04015 Rap1 signaling pathway
102986916 (BRAF)
04068 FoxO signaling pathway
102986916 (BRAF)
04024 cAMP signaling pathway
102986916 (BRAF)
04150 mTOR signaling pathway
102986916 (BRAF)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
102986916 (BRAF)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102986916 (BRAF)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
102986916 (BRAF)
04062 Chemokine signaling pathway
102986916 (BRAF)
09152 Endocrine system
04910 Insulin signaling pathway
102986916 (BRAF)
04914 Progesterone-mediated oocyte maturation
102986916 (BRAF)
04928 Parathyroid hormone synthesis, secretion and action
102986916 (BRAF)
09153 Circulatory system
04270 Vascular smooth muscle contraction
102986916 (BRAF)
09156 Nervous system
04726 Serotonergic synapse
102986916 (BRAF)
04720 Long-term potentiation
102986916 (BRAF)
04730 Long-term depression
102986916 (BRAF)
04722 Neurotrophin signaling pathway
102986916 (BRAF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102986916 (BRAF)
05205 Proteoglycans in cancer
102986916 (BRAF)
09162 Cancer: specific types
05210 Colorectal cancer
102986916 (BRAF)
05212 Pancreatic cancer
102986916 (BRAF)
05225 Hepatocellular carcinoma
102986916 (BRAF)
05226 Gastric cancer
102986916 (BRAF)
05214 Glioma
102986916 (BRAF)
05216 Thyroid cancer
102986916 (BRAF)
05221 Acute myeloid leukemia
102986916 (BRAF)
05220 Chronic myeloid leukemia
102986916 (BRAF)
05218 Melanoma
102986916 (BRAF)
05211 Renal cell carcinoma
102986916 (BRAF)
05219 Bladder cancer
102986916 (BRAF)
05215 Prostate cancer
102986916 (BRAF)
05213 Endometrial cancer
102986916 (BRAF)
05224 Breast cancer
102986916 (BRAF)
05223 Non-small cell lung cancer
102986916 (BRAF)
09164 Neurodegenerative disease
05010 Alzheimer disease
102986916 (BRAF)
05022 Pathways of neurodegeneration - multiple diseases
102986916 (BRAF)
09165 Substance dependence
05034 Alcoholism
102986916 (BRAF)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
102986916 (BRAF)
09172 Infectious disease: viral
05161 Hepatitis B
102986916 (BRAF)
05160 Hepatitis C
102986916 (BRAF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102986916 (BRAF)
01522 Endocrine resistance
102986916 (BRAF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcad01001
]
102986916 (BRAF)
Enzymes [BR:
pcad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
102986916 (BRAF)
Protein kinases [BR:
pcad01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
102986916 (BRAF)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
C1_2
Pkinase_fungal
APH
Kdo
Motif
Other DBs
NCBI-GeneID:
102986916
NCBI-ProteinID:
XP_023983693
UniProt:
A0A2Y9SZY4
LinkDB
All DBs
Position
5
AA seq
779 aa
AA seq
DB search
MAALSGGGGGGADQGQALFNGDMEPEAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEAL
LDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASTDTVTSSS
SSSLSVLPSSLSVFQNPTDVSRSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKA
LMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFT
LAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEE
ASLAETTLTSGSSPSAPPSDSIGPPILTSPSPSKSIPIPQPFRPDEDHRNQFGQRDRSSS
APNVHINTIEPVNIDDLIRDQGFRSDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQRE
RKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKML
NVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIE
TKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWS
GSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQI
IFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQERSRRKYRLFNSGYPW
KILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGEFAAFK
NT seq
2340 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgttgagcggcggcggcggcggcggcgcggaccagggccaggctctgttcaac
ggggatatggagcccgaggccggcgccgcggcctcttcggctgcggacccggccattccc
gaggaggtgtggaatatcaaacaaatgattaaattgacacaggagcatatagaggcccta
ctggacaaatttggtggggagcataatccaccatcaatatatctggaggcctatgaagaa
tacaccagcaagctagatgccctccaacaaagagaacaacagttattggaatccctgggg
aatggaactgatttttctgtttctagctctgcatcaacagacaccgttacatcttcttcc
tcttctagcctttcagtgctgccttcatctctttcagtttttcaaaatcccacagatgtg
tcacggagcaaccccaagtcaccacaaaaacctatcgttagagtcttcctgcccaataaa
cagaggacagtggtacctgcaaggtgtggagttacagtccgggacagcctaaagaaagca
ctgatgatgagaggtctaatcccagagtgctgtgctgtttacagaattcaggatggagag
aagaaaccaattggctgggatactgatatttcctggcttactggagaggaattgcatgta
gaagtgttggagaatgttccacttacaacacacaactttgtacggaaaacttttttcacc
ttagcattttgtgacttctgtcgaaagctgcttttccaggggttccgctgtcaaacatgt
ggttataaatttcaccagcgttgtagtacagaggttccactgatgtgtgttaattatgac
caacttgatttgctgtttgtctccaagttctttgaacaccacccaataccacaggaggag
gcctccttagcagagactacccttacatctggatcgtccccttctgcacccccctccgat
tctattgggcccccaattctcaccagtccgtctccttcaaaatccattccaattccacag
cctttccgaccagatgaagatcatcgaaatcagtttggacagcgagatcggtcctcatca
gctccaaatgtgcatataaacaccatagaacctgtcaatattgatgacttgattagagac
caagggtttcgtagtgatggaggatcaaccacaggtttatctgccacgccccctgcctca
ttacctggctcactcactaatgtgaaagcattacagaaatctccaggacctcagcgagaa
aggaagtcatcttcatcctcagaagacaggaatcgaatgaaaacacttggtagacgggat
tcaagtgacgattgggagattcctgatgggcagatcacggtgggacaaagaattggatcc
gggtcatttgggacagtctacaagggaaagtggcatggtgatgtggcagtgaaaatgttg
aatgtgacagcacccacacctcagcagttacaggccttcaaaaatgaagtaggagtactc
aggaaaactcgacatgtgaatatcctactcttcatgggttattcaacaaagccacaactg
gctattgttacccagtggtgtgagggctccagcttatatcatcatctccacatcattgag
accaaattcgagatgatcaaacttatagatattgcacggcagactgcacagggcatggat
tacttacacgccaagtcaatcatccacagagacctcaagagtaataatatttttcttcat
gaagacctcacagtaaaaataggtgattttggtctagccacagtgaaatctcgatggagt
gggtcccatcaatttgaacagttgtctggatccattttgtggatggcaccagaagtaatc
agaatgcaagataaaaacccatatagctttcagtcagatgtatatgcatttgggattgtt
ctgtatgaattgatgaccggacagttaccttattcaaacatcaacaacagggaccagata
atttttatggtgggacgaggatatctatctccagatctcagtaaggtacggagtaactgt
ccaaaagccatgaagagactaatggcagagtgcctaaaaaagaaaagagatgagagacca
ctctttccccaagaaaggtccagaagaaagtatagactctttaacagtggttacccctgg
aagattctcgcctctattgagctgctggcccgctcattgccaaaaattcaccgcagtgca
tccgaaccctctttgaatcgggctggcttccaaacagaggattttagtctgtatgcttgt
gcttctccaaaaacacccatccaggcagggggatatggagaatttgcagccttcaagtag
Physeter catodon (sperm whale): 102987866
Help
Entry
102987866 CDS
T06011
Gene name
RAF1
Definition
(RefSeq) RAF proto-oncogene serine/threonine-protein kinase isoform X2
KO
K04366
RAF proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
pcad
Physeter catodon (sperm whale)
Pathway
pcad01521
EGFR tyrosine kinase inhibitor resistance
pcad01522
Endocrine resistance
pcad04010
MAPK signaling pathway
pcad04012
ErbB signaling pathway
pcad04014
Ras signaling pathway
pcad04015
Rap1 signaling pathway
pcad04022
cGMP-PKG signaling pathway
pcad04024
cAMP signaling pathway
pcad04062
Chemokine signaling pathway
pcad04068
FoxO signaling pathway
pcad04071
Sphingolipid signaling pathway
pcad04072
Phospholipase D signaling pathway
pcad04140
Autophagy - animal
pcad04150
mTOR signaling pathway
pcad04151
PI3K-Akt signaling pathway
pcad04210
Apoptosis
pcad04218
Cellular senescence
pcad04270
Vascular smooth muscle contraction
pcad04360
Axon guidance
pcad04370
VEGF signaling pathway
pcad04371
Apelin signaling pathway
pcad04510
Focal adhesion
pcad04540
Gap junction
pcad04550
Signaling pathways regulating pluripotency of stem cells
pcad04613
Neutrophil extracellular trap formation
pcad04625
C-type lectin receptor signaling pathway
pcad04630
JAK-STAT signaling pathway
pcad04650
Natural killer cell mediated cytotoxicity
pcad04660
T cell receptor signaling pathway
pcad04662
B cell receptor signaling pathway
pcad04664
Fc epsilon RI signaling pathway
pcad04666
Fc gamma R-mediated phagocytosis
pcad04720
Long-term potentiation
pcad04722
Neurotrophin signaling pathway
pcad04726
Serotonergic synapse
pcad04730
Long-term depression
pcad04810
Regulation of actin cytoskeleton
pcad04910
Insulin signaling pathway
pcad04912
GnRH signaling pathway
pcad04914
Progesterone-mediated oocyte maturation
pcad04915
Estrogen signaling pathway
pcad04916
Melanogenesis
pcad04917
Prolactin signaling pathway
pcad04919
Thyroid hormone signaling pathway
pcad04921
Oxytocin signaling pathway
pcad04926
Relaxin signaling pathway
pcad04928
Parathyroid hormone synthesis, secretion and action
pcad04929
GnRH secretion
pcad04935
Growth hormone synthesis, secretion and action
pcad05010
Alzheimer disease
pcad05022
Pathways of neurodegeneration - multiple diseases
pcad05034
Alcoholism
pcad05132
Salmonella infection
pcad05152
Tuberculosis
pcad05160
Hepatitis C
pcad05161
Hepatitis B
pcad05163
Human cytomegalovirus infection
pcad05164
Influenza A
pcad05165
Human papillomavirus infection
pcad05167
Kaposi sarcoma-associated herpesvirus infection
pcad05170
Human immunodeficiency virus 1 infection
pcad05200
Pathways in cancer
pcad05205
Proteoglycans in cancer
pcad05206
MicroRNAs in cancer
pcad05210
Colorectal cancer
pcad05211
Renal cell carcinoma
pcad05212
Pancreatic cancer
pcad05213
Endometrial cancer
pcad05214
Glioma
pcad05215
Prostate cancer
pcad05218
Melanoma
pcad05219
Bladder cancer
pcad05220
Chronic myeloid leukemia
pcad05221
Acute myeloid leukemia
pcad05223
Non-small cell lung cancer
pcad05224
Breast cancer
pcad05225
Hepatocellular carcinoma
pcad05226
Gastric cancer
pcad05230
Central carbon metabolism in cancer
pcad05231
Choline metabolism in cancer
pcad05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102987866 (RAF1)
04012 ErbB signaling pathway
102987866 (RAF1)
04014 Ras signaling pathway
102987866 (RAF1)
04015 Rap1 signaling pathway
102987866 (RAF1)
04370 VEGF signaling pathway
102987866 (RAF1)
04371 Apelin signaling pathway
102987866 (RAF1)
04630 JAK-STAT signaling pathway
102987866 (RAF1)
04068 FoxO signaling pathway
102987866 (RAF1)
04072 Phospholipase D signaling pathway
102987866 (RAF1)
04071 Sphingolipid signaling pathway
102987866 (RAF1)
04024 cAMP signaling pathway
102987866 (RAF1)
04022 cGMP-PKG signaling pathway
102987866 (RAF1)
04151 PI3K-Akt signaling pathway
102987866 (RAF1)
04150 mTOR signaling pathway
102987866 (RAF1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102987866 (RAF1)
09143 Cell growth and death
04210 Apoptosis
102987866 (RAF1)
04218 Cellular senescence
102987866 (RAF1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
102987866 (RAF1)
04540 Gap junction
102987866 (RAF1)
04550 Signaling pathways regulating pluripotency of stem cells
102987866 (RAF1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102987866 (RAF1)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
102987866 (RAF1)
04625 C-type lectin receptor signaling pathway
102987866 (RAF1)
04650 Natural killer cell mediated cytotoxicity
102987866 (RAF1)
04660 T cell receptor signaling pathway
102987866 (RAF1)
04662 B cell receptor signaling pathway
102987866 (RAF1)
04664 Fc epsilon RI signaling pathway
102987866 (RAF1)
04666 Fc gamma R-mediated phagocytosis
102987866 (RAF1)
04062 Chemokine signaling pathway
102987866 (RAF1)
09152 Endocrine system
04910 Insulin signaling pathway
102987866 (RAF1)
04929 GnRH secretion
102987866 (RAF1)
04912 GnRH signaling pathway
102987866 (RAF1)
04915 Estrogen signaling pathway
102987866 (RAF1)
04914 Progesterone-mediated oocyte maturation
102987866 (RAF1)
04917 Prolactin signaling pathway
102987866 (RAF1)
04921 Oxytocin signaling pathway
102987866 (RAF1)
04926 Relaxin signaling pathway
102987866 (RAF1)
04935 Growth hormone synthesis, secretion and action
102987866 (RAF1)
04919 Thyroid hormone signaling pathway
102987866 (RAF1)
04928 Parathyroid hormone synthesis, secretion and action
102987866 (RAF1)
04916 Melanogenesis
102987866 (RAF1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
102987866 (RAF1)
09156 Nervous system
04726 Serotonergic synapse
102987866 (RAF1)
04720 Long-term potentiation
102987866 (RAF1)
04730 Long-term depression
102987866 (RAF1)
04722 Neurotrophin signaling pathway
102987866 (RAF1)
09158 Development and regeneration
04360 Axon guidance
102987866 (RAF1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102987866 (RAF1)
05206 MicroRNAs in cancer
102987866 (RAF1)
05205 Proteoglycans in cancer
102987866 (RAF1)
05230 Central carbon metabolism in cancer
102987866 (RAF1)
05231 Choline metabolism in cancer
102987866 (RAF1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102987866 (RAF1)
09162 Cancer: specific types
05210 Colorectal cancer
102987866 (RAF1)
05212 Pancreatic cancer
102987866 (RAF1)
05225 Hepatocellular carcinoma
102987866 (RAF1)
05226 Gastric cancer
102987866 (RAF1)
05214 Glioma
102987866 (RAF1)
05221 Acute myeloid leukemia
102987866 (RAF1)
05220 Chronic myeloid leukemia
102987866 (RAF1)
05218 Melanoma
102987866 (RAF1)
05211 Renal cell carcinoma
102987866 (RAF1)
05219 Bladder cancer
102987866 (RAF1)
05215 Prostate cancer
102987866 (RAF1)
05213 Endometrial cancer
102987866 (RAF1)
05224 Breast cancer
102987866 (RAF1)
05223 Non-small cell lung cancer
102987866 (RAF1)
09164 Neurodegenerative disease
05010 Alzheimer disease
102987866 (RAF1)
05022 Pathways of neurodegeneration - multiple diseases
102987866 (RAF1)
09165 Substance dependence
05034 Alcoholism
102987866 (RAF1)
09171 Infectious disease: bacterial
05132 Salmonella infection
102987866 (RAF1)
05152 Tuberculosis
102987866 (RAF1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
102987866 (RAF1)
05161 Hepatitis B
102987866 (RAF1)
05160 Hepatitis C
102987866 (RAF1)
05164 Influenza A
102987866 (RAF1)
05163 Human cytomegalovirus infection
102987866 (RAF1)
05167 Kaposi sarcoma-associated herpesvirus infection
102987866 (RAF1)
05165 Human papillomavirus infection
102987866 (RAF1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102987866 (RAF1)
01522 Endocrine resistance
102987866 (RAF1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcad01001
]
102987866 (RAF1)
Enzymes [BR:
pcad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
102987866 (RAF1)
Protein kinases [BR:
pcad01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
102987866 (RAF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
Pkinase_fungal
C1_2
Motif
Other DBs
NCBI-GeneID:
102987866
NCBI-ProteinID:
XP_007126260
UniProt:
A0A2Y9FMZ7
LinkDB
All DBs
Position
18
AA seq
648 aa
AA seq
DB search
MEHIQGAWKTISNGFGFKDAVFDGPSCISPTIVQQFGYQRRASDDGKLTDPSKTSSTIRV
FLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAAS
LIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKV
PTMCVDWSNIRQLLLFPNSTVGDSGVPTLPSLTMRRMRESVSRMPVSSQHRYSTPHAFTF
NTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHGESGSPSALSSSPNNL
SPTGWSQPKTPVPAQRERAPGSSTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF
GTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIV
TQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGL
TVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDNNPFSFQSDVYSYGIVLYE
LMTGELPYSHISNRDQIIFMVGRGYTSPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFP
QILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
NT seq
1947 nt
NT seq
+upstream
nt +downstream
nt
atggagcacatacagggggcctggaagacgatcagcaatggttttggattcaaagacgca
gtgtttgatggccccagctgcatctcccctacaatagttcagcagtttggctatcagcgt
cgggcatcagatgatggcaaacttacggacccttctaagacaagcagcactatccgtgtt
tttttgccaaacaagcaaagaacagtggtcaatgtgcggaatggaatgagcttgcatgac
tgccttatgaaagctctcaaggtgaggggcctgcaaccagagtgctgtgcagttttcaga
cttctccacgaacacaagggtaaaaaagcacgtttagattggaatactgatgctgcctcg
ttgattggagaggaacttcaagtagatttcctggaccatgttccactcacaacacacaac
tttgctcggaagaccttcctgaagcttgccttctgtgacatctgtcagaagttcctgctg
aatgggtttagatgtcagacttgtggctacaagtttcacgagcattgtagcaccaaagta
cctactatgtgtgtggactggagtaatatcagacaactcttgctgttcccaaattccact
gttggtgatagtggggtcccaacactgccttctttgacaatgcgtcggatgcgagagtct
gtttcccggatgcctgttagttcccagcacagatactccacaccccacgctttcacattc
aacacctccagcccctcctctgaaggttccctgtcccagaggcagaggtcgacgtccaca
cctaatgtccacatggtcagcaccaccttgcccgtggacagcaggatgattgaggatgca
attcggagtcatggtgaatcaggctcaccttcagccttgtccagcagtcccaacaatctg
agcccaacaggctggtcacagcccaaaacccctgtgccggcacagagagagcgggcaccg
ggatccagcacccaggagaaaaacaaaattaggcctcgtggacagagagattcaagctat
tactgggaaatagaagccagtgaagtgatgctctccactcggattgggtcaggctccttt
ggaactgtttataagggcaagtggcatggagacgttgcagtaaagattctaaaggttgtt
gaccccacaccagagcagttccaggccttcaggaatgaagtggctgtccttcgcaaaacc
cggcacgtgaacatcctgctcttcatggggtacatgacgaaggacaacctggcaattgtg
acccagtggtgcgagggcagcagcctctataaacacctgcacgtccaggagaccaagttc
cagatgttccagttgattgacattgcccggcagacggctcagggaatggactatttgcat
gcaaagaacatcatccacagagacatgaaatccaacaatatatttctccatgaaggcctg
acggtgaaaattggagactttggtttggcaacagtgaagtcgcgctggagtggttctcag
caggttgaacaacccaccggctccatcttgtggatggccccagaggtgattcgaatgcag
gacaataacccgttcagcttccagtctgacgtctactcgtacggcatcgtgctgtatgag
ctcatgacaggggagctgccctactcccacatcagcaaccgcgatcagatcatcttcatg
gtaggccgagggtacacctccccagaccttagtaagctgtacaagaactgccccaaagca
atgaagaggctggtagccgactgtgtgaagaaagttaaggaagagaggcctctttttccc
cagatcctgtcttccattgagctgctccaacactctctaccgaaaatcaaccggagcgct
tctgagccatccctgcaccgggcggcccataccgaggacatcaatgcctgcacgctgacc
acatcccctagattgcctgtcttctag
DBGET
integrated database retrieval system
