Physeter catodon (sperm whale): 102978925
Help
Entry
102978925 CDS
T06011
Gene name
SOS2
Definition
(RefSeq) son of sevenless homolog 2
KO
K03099
son of sevenless
Organism
pcad
Physeter catodon (sperm whale)
Pathway
pcad01521
EGFR tyrosine kinase inhibitor resistance
pcad01522
Endocrine resistance
pcad04010
MAPK signaling pathway
pcad04012
ErbB signaling pathway
pcad04014
Ras signaling pathway
pcad04062
Chemokine signaling pathway
pcad04068
FoxO signaling pathway
pcad04072
Phospholipase D signaling pathway
pcad04150
mTOR signaling pathway
pcad04151
PI3K-Akt signaling pathway
pcad04510
Focal adhesion
pcad04540
Gap junction
pcad04630
JAK-STAT signaling pathway
pcad04650
Natural killer cell mediated cytotoxicity
pcad04660
T cell receptor signaling pathway
pcad04662
B cell receptor signaling pathway
pcad04664
Fc epsilon RI signaling pathway
pcad04714
Thermogenesis
pcad04722
Neurotrophin signaling pathway
pcad04810
Regulation of actin cytoskeleton
pcad04910
Insulin signaling pathway
pcad04912
GnRH signaling pathway
pcad04915
Estrogen signaling pathway
pcad04917
Prolactin signaling pathway
pcad04926
Relaxin signaling pathway
pcad04935
Growth hormone synthesis, secretion and action
pcad05034
Alcoholism
pcad05160
Hepatitis C
pcad05161
Hepatitis B
pcad05163
Human cytomegalovirus infection
pcad05165
Human papillomavirus infection
pcad05200
Pathways in cancer
pcad05205
Proteoglycans in cancer
pcad05206
MicroRNAs in cancer
pcad05210
Colorectal cancer
pcad05211
Renal cell carcinoma
pcad05213
Endometrial cancer
pcad05214
Glioma
pcad05215
Prostate cancer
pcad05220
Chronic myeloid leukemia
pcad05221
Acute myeloid leukemia
pcad05223
Non-small cell lung cancer
pcad05224
Breast cancer
pcad05225
Hepatocellular carcinoma
pcad05226
Gastric cancer
pcad05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102978925 (SOS2)
04012 ErbB signaling pathway
102978925 (SOS2)
04014 Ras signaling pathway
102978925 (SOS2)
04630 JAK-STAT signaling pathway
102978925 (SOS2)
04068 FoxO signaling pathway
102978925 (SOS2)
04072 Phospholipase D signaling pathway
102978925 (SOS2)
04151 PI3K-Akt signaling pathway
102978925 (SOS2)
04150 mTOR signaling pathway
102978925 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
102978925 (SOS2)
04540 Gap junction
102978925 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102978925 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
102978925 (SOS2)
04660 T cell receptor signaling pathway
102978925 (SOS2)
04662 B cell receptor signaling pathway
102978925 (SOS2)
04664 Fc epsilon RI signaling pathway
102978925 (SOS2)
04062 Chemokine signaling pathway
102978925 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
102978925 (SOS2)
04912 GnRH signaling pathway
102978925 (SOS2)
04915 Estrogen signaling pathway
102978925 (SOS2)
04917 Prolactin signaling pathway
102978925 (SOS2)
04926 Relaxin signaling pathway
102978925 (SOS2)
04935 Growth hormone synthesis, secretion and action
102978925 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
102978925 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
102978925 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102978925 (SOS2)
05206 MicroRNAs in cancer
102978925 (SOS2)
05205 Proteoglycans in cancer
102978925 (SOS2)
05231 Choline metabolism in cancer
102978925 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
102978925 (SOS2)
05225 Hepatocellular carcinoma
102978925 (SOS2)
05226 Gastric cancer
102978925 (SOS2)
05214 Glioma
102978925 (SOS2)
05221 Acute myeloid leukemia
102978925 (SOS2)
05220 Chronic myeloid leukemia
102978925 (SOS2)
05211 Renal cell carcinoma
102978925 (SOS2)
05215 Prostate cancer
102978925 (SOS2)
05213 Endometrial cancer
102978925 (SOS2)
05224 Breast cancer
102978925 (SOS2)
05223 Non-small cell lung cancer
102978925 (SOS2)
09165 Substance dependence
05034 Alcoholism
102978925 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
102978925 (SOS2)
05160 Hepatitis C
102978925 (SOS2)
05163 Human cytomegalovirus infection
102978925 (SOS2)
05165 Human papillomavirus infection
102978925 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102978925 (SOS2)
01522 Endocrine resistance
102978925 (SOS2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04990 Domain-containing proteins not elsewhere classified [BR:
pcad04990
]
102978925 (SOS2)
Domain-containing proteins not elsewhere classified [BR:
pcad04990
]
Pleckstrin homology (PH) domain-containing proteins
Dbl-Like RhoGEF family proteins
102978925 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
Histone
PH
IQ_SEC7_PH
PH_19
PH_13
Motif
Other DBs
NCBI-GeneID:
102978925
NCBI-ProteinID:
XP_023971777
UniProt:
A0A2Y9S2X5
LinkDB
All DBs
Position
11
AA seq
1332 aa
AA seq
DB search
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRNLFKPSDI
EKIFSNILDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEHEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKSNHSQSRLPG
YSSAEYRLKEKFVMRKVQICDKEDTCECKHAFELVSKDENSIIFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPSEADKLA
VEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILD
DAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGNASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDASNSKGTMKSDDDPPAIPPRQPPPPKVKPRVPAPTGAFDGPL
HSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFTLQPPPLGHLHRDPDWFRDVSTCPNSPN
TPLSTPSPRVPRRCYVLSSSQNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPLY
RLPLLENAETPQ
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccgtacgagttcttcagcgaagagaacagtccgaaatggcgg
ggactgttggtctcagccctgcggaaggttcaggagcaagtacatcccaatctctcagct
aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc
atggcccaaccaaggactgttcaagatgtggaggaacgagttcaaaagacctttcctcat
ccaattgataaatgggctattgctgatgcacagtctgccatagagaaacgaaaacgaaga
aatcctctcttactgcctgtggacaaaatccatccttcattgaaggaagttttagggtac
aaagtggactaccatgtgtcactatatattgtggctgttctagagtatatctcagctgat
attttgaaattggctggtaattatgtttttaatatccgacattatgaaatatcgcaacag
gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac
ataggcttggtttctctttgtgaagatgaacctagttcttcaggtgaattaaactactat
gaccttgtcagaactgaaattgcagaagaaagacagtacctacgggaactaaatatgatc
ataaaagtatttcgagaagcttttctttctgacagaaacctgtttaaaccttctgatatt
gaaaagattttcagtaacattttagatatacatgaattgaccgtgaaacttttaggttta
attgaagacacagttgaaatgactgatgaaagcagccctcatcccttagctggaagctgt
tttgaagatttagcagaggaacaagcatttgatccttatgaaacattatcacaggatatt
ctttcaccaaaatttaatgaacatttcagtaagttgatggccagacctgcagtggctcta
cactttcagtccattgctgatggttttaaagaggcagttcgttatgtccttccacgcctt
atgctggtgccagtatatcattgttggcactattttgaattattaaagcaattgaaagca
tgtagtgaagagcatgaagacagagaatgtttgaaccaagctattactgctctcatgaat
ctccaaggtagtatggaccgaatttacaagcagtattcacctagacgccgacctggggat
cctgtttgccctttttataatcgtcaattaagaagcaagcacctggctattaaaaaaatg
aatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgtaat
gaatttattatggaaggcccattgacaagaattggtgctaaacacgaacggcatattttt
ctctttgatggcttaatgattagctgcaaatccaatcatagccagtcacgccttccagga
tacagtagtgcagaatacagattaaaagaaaaatttgtcatgaggaaagtacaaatatgt
gataaagaagatacttgtgaatgcaaacatgcttttgaattagtatccaaagatgaaaac
agcataatatttgctgctaagtctgctgaagagaaaaataattggatggcagcacttatt
tctcttcattatcgtagtactctagatcgaatgctagattcagtattactgaaggaagaa
aatgaacaaccacttagattaccgagtcctgaagtgtatcgttttgtggtaaaagactct
gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggaatccccattattaaa
ggaggaactgtggtgaaattaattgaaaggttaacatatcacatgtatgcagatcccaat
tttgttcgtacttttcttactacgtatcgttcattttgtaaaccacaggaattgctaagc
ttactgattgaacgatttgaaattccagagccagaaccttctgaagcagataaattggca
gtagagaaaggcgagcagccaatcagtgcagaccttaaaaggtttcgcaaggaatacgtc
caaccagtacaacttaggatcttaaatgtgtttcggcactgggttgaacaccatttttat
gactttgaaagagacttggagttgcttgaaaggctagaatccttcatttcaagtgtaaga
gggaaagctatgaagaaatgggtagagtcaattgctaagatcatcaagaggaagaaacaa
gctcaggcaaatggaataagccataatattacctttgaaagtccacctccaccaattgaa
tggcatatcagcagaccaggacagtttgaaacgtttgatctcatgacacttcatccaata
gaaattgcacgtcagctgacacttttggaatctgatctctacaggaaagttcaaccttca
gaacttgtagggagtgtatggacgaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgccacaccacaaatctcactctctggtttgaaaagtgcattgtggaagca
gaaaattttgaggaacgggtggcagtactaagtagaattatagaaattctgcaagttttt
caagatttgaataatttcaatggtgtattagagatcgtcagtgcagtaaattcagtatca
gtctatagactagatcatacctttgaggcattgcaggaaagaaaaaggaaaattttggat
gatgctgtggaattaagtcaagatcattttaaaaaatatctagtgaaacttaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaagactgaagaa
gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtagctgaaattactggagaaattcagcaatatcagaatcaaccttactgtttacgg
atagaaccagaaatgaggaggttctttgaaaaccttaaccccatgggaaatgcttctgaa
aaagagtttacagattatttgttcaacaagtcactagaaattgaaccccgaaactgcaaa
cagccacctcgatttcctaggaaatcaactttctctttaaaatctcctggaataaggcct
aatacaggccgacatggctctacctcaggtactttacgaggtcatccaacaccattagaa
agagaaccatgtaaaataagctttagtcggattgctgaaacagagcttgaatcaacagtg
tcagcaccaacctctccaaatacaccatctactccaccagtatctgcttcttcagacctt
agtgtgtttttagatgtggatctcaacagttcctgtggaagcaatagcatctttgctcca
gtcctcttgcctcattcaaagtctttctttagttcgtgtggtagtttacataagctaagt
gaagagccactgattcctcctccacttcctcctcgaaaaaaatttgatcacgatgcttca
aattccaagggaactatgaaatctgatgatgacccccctgctattccgccaagacagcct
cctcctccaaaggtaaaacccagagttcctgctcctactggtgcatttgacgggcctctg
catagtccaccaccgccgccgccgagagatcctcttcccgatacccctccaccagttccc
cttcggcctccagaacactttataaactgtccatttactcttcagccacctccactggga
catcttcacagagatccagactggttcagagacgttagtacgtgtccaaattctccaaac
actcctcttagcacaccctctccaagggtaccacgtcgatgctatgtgctcagttctagt
caaaataatcttgctcatcctcaagctccccctgttccaccaaggcagaattcaagccct
catctaccaaaactgccaccaaagacttacaaacgggagctttcacaccccccattgtat
agactgcctttgctagaaaatgcagaaactcctcaatga
Physeter catodon (sperm whale): 102981677
Help
Entry
102981677 CDS
T06011
Definition
(RefSeq) LOW QUALITY PROTEIN: son of sevenless homolog 2-like
KO
K03099
son of sevenless
Organism
pcad
Physeter catodon (sperm whale)
Pathway
pcad01521
EGFR tyrosine kinase inhibitor resistance
pcad01522
Endocrine resistance
pcad04010
MAPK signaling pathway
pcad04012
ErbB signaling pathway
pcad04014
Ras signaling pathway
pcad04062
Chemokine signaling pathway
pcad04068
FoxO signaling pathway
pcad04072
Phospholipase D signaling pathway
pcad04150
mTOR signaling pathway
pcad04151
PI3K-Akt signaling pathway
pcad04510
Focal adhesion
pcad04540
Gap junction
pcad04630
JAK-STAT signaling pathway
pcad04650
Natural killer cell mediated cytotoxicity
pcad04660
T cell receptor signaling pathway
pcad04662
B cell receptor signaling pathway
pcad04664
Fc epsilon RI signaling pathway
pcad04714
Thermogenesis
pcad04722
Neurotrophin signaling pathway
pcad04810
Regulation of actin cytoskeleton
pcad04910
Insulin signaling pathway
pcad04912
GnRH signaling pathway
pcad04915
Estrogen signaling pathway
pcad04917
Prolactin signaling pathway
pcad04926
Relaxin signaling pathway
pcad04935
Growth hormone synthesis, secretion and action
pcad05034
Alcoholism
pcad05160
Hepatitis C
pcad05161
Hepatitis B
pcad05163
Human cytomegalovirus infection
pcad05165
Human papillomavirus infection
pcad05200
Pathways in cancer
pcad05205
Proteoglycans in cancer
pcad05206
MicroRNAs in cancer
pcad05210
Colorectal cancer
pcad05211
Renal cell carcinoma
pcad05213
Endometrial cancer
pcad05214
Glioma
pcad05215
Prostate cancer
pcad05220
Chronic myeloid leukemia
pcad05221
Acute myeloid leukemia
pcad05223
Non-small cell lung cancer
pcad05224
Breast cancer
pcad05225
Hepatocellular carcinoma
pcad05226
Gastric cancer
pcad05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102981677
04012 ErbB signaling pathway
102981677
04014 Ras signaling pathway
102981677
04630 JAK-STAT signaling pathway
102981677
04068 FoxO signaling pathway
102981677
04072 Phospholipase D signaling pathway
102981677
04151 PI3K-Akt signaling pathway
102981677
04150 mTOR signaling pathway
102981677
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
102981677
04540 Gap junction
102981677
09142 Cell motility
04810 Regulation of actin cytoskeleton
102981677
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
102981677
04660 T cell receptor signaling pathway
102981677
04662 B cell receptor signaling pathway
102981677
04664 Fc epsilon RI signaling pathway
102981677
04062 Chemokine signaling pathway
102981677
09152 Endocrine system
04910 Insulin signaling pathway
102981677
04912 GnRH signaling pathway
102981677
04915 Estrogen signaling pathway
102981677
04917 Prolactin signaling pathway
102981677
04926 Relaxin signaling pathway
102981677
04935 Growth hormone synthesis, secretion and action
102981677
09156 Nervous system
04722 Neurotrophin signaling pathway
102981677
09159 Environmental adaptation
04714 Thermogenesis
102981677
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102981677
05206 MicroRNAs in cancer
102981677
05205 Proteoglycans in cancer
102981677
05231 Choline metabolism in cancer
102981677
09162 Cancer: specific types
05210 Colorectal cancer
102981677
05225 Hepatocellular carcinoma
102981677
05226 Gastric cancer
102981677
05214 Glioma
102981677
05221 Acute myeloid leukemia
102981677
05220 Chronic myeloid leukemia
102981677
05211 Renal cell carcinoma
102981677
05215 Prostate cancer
102981677
05213 Endometrial cancer
102981677
05224 Breast cancer
102981677
05223 Non-small cell lung cancer
102981677
09165 Substance dependence
05034 Alcoholism
102981677
09172 Infectious disease: viral
05161 Hepatitis B
102981677
05160 Hepatitis C
102981677
05163 Human cytomegalovirus infection
102981677
05165 Human papillomavirus infection
102981677
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102981677
01522 Endocrine resistance
102981677
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04990 Domain-containing proteins not elsewhere classified [BR:
pcad04990
]
102981677
Domain-containing proteins not elsewhere classified [BR:
pcad04990
]
Pleckstrin homology (PH) domain-containing proteins
Dbl-Like RhoGEF family proteins
102981677
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
PH
Histone
PH_13
Motif
Other DBs
NCBI-GeneID:
102981677
NCBI-ProteinID:
XP_023980472
UniProt:
A0A2Y9SSQ6
LinkDB
All DBs
Position
8
AA seq
1325 aa
AA seq
DB search
MPQAPQPYEFFSAENSPKWRGLLVSALPKVQEQVHPNLSADEEPIFQLLNKLCMAQPRTV
QDVAEVQKTFSHPVDEWAIADAQSATEKRKRRNPLLLPVDKIHPSLKEVLGYKVDYHVSL
YSVAVLEYISAGILKLAGNYVFNIRHYEISQQDIKVSVCADKVLMDMFDQDDIGLVSLCE
DEPSSSGELNYYDLVRTEIAEERQYLRKLNMIIKVFRKVFLSDRKLFKSSDIEKVFSNIL
DIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLTEEQAFDPYETLSQDILSPKFNEH
FSKLMAIPAVALQFQSIADGFKEAVYYVLPHLMLVPVYHCWHYFELLKQLKACSEEHEDR
ECLNQAITALMNLQGSLDRIYKQYSPRCXPGDPVYPFYNHQLRSKHLAIKKMNEIQKNID
GWEGKDIGQCCNEFIMEGPLTRIGAKHEWHIFLFDGCLMISCKPNHSQSHLPGYHSTEYR
LKEKFVMRKIQICDKEDTCECKHAFELVSKDENSIIFAARSAEEKNNWMAALISLHYRST
LDQMLDSVLLKEENEQPLKLPSPEVYRFVVKDSXENIVFEDNLQSRSGIPIIKGGAVVKL
IERLTYHMYADPNFVRTFLTMYRSFCKPQELLSLLIERFEIPEPEPTEADKLAVEKGEQP
ISADLKRFHKEYVQPVQLRILNVFRHWVEHHYYHFERDLELLERLESFISSVRGKAMKKW
VESIAKIIKRKKQAQANGISHNITFQSLPPPTEWHISRPGQFETFDLMTLHPIEIARQLT
LLESDLYSKVQPSELVGHVWTKEDKEIDSPNLLKMIHHTTNLTLWFEKCIVEAENFEERV
AVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTSEERKRKILDEAVELSQDHX
KKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRRKRRKVPEITG
EIQQYQNQPYCLWIEPEMRRFFENLNPMGNASEKEFTDYLFNKSLEIEPGNSKQPPRFPR
NSTFSLKSPGIRPNTGRHGSTSGTLWGRPTPLERELCKISFSRIAETELESTVSAPTSPN
TPSTPPVSASSDLSVFLDVDLSSSCGSNSIFAPVLLPHSESFFSSCGSLHKLSEEPLIPP
ALSPRNKFDHDASNSKGTMKSDDDPPAILPRQPPPPKVKPRVPVPTGAFDGPLHSPPPPP
PRDPFPNTPPPVPLRPPEHFINCPFTLQPPPLGHLHRDPDWFRDVSTCPNSPNTPLSTPS
PRVPRXCYVLSSSQNNLAHPQAPPVPPRQDSSPHLPKLPPKTYKRELSHPPLYRLPLLEN
AETPQ
NT seq
3978 nt
NT seq
+upstream
nt +downstream
nt
atgccgcaggcgccgcagccgtacgagttcttcagcgcagagaacagtccgaaatggcgg
ggactgttggtctcggccctgccgaaggttcaggagcaagtacatcccaatctctcagct
gatgaagagccgatttttcagctgcttaataaattatgcatggcccaaccaaggactgtt
caagatgtggcggaagttcaaaagaccttttctcatccagtggatgaatgggctattgct
gatgcacagtctgccacagagaaacgaaaacgaagaaatcctctcttactgcctgtggac
aaaatccatccttcattgaaggaagttttagggtacaaagtggactaccatgtgtcccta
tatagtgtggctgtactagagtatatctcagctggtattttgaaattggctggtaattat
gtttttaatatccgacattatgaaatatcccaacaggacattaaagtgtcagtgtgtgca
gataaggttttgatggacatgtttgatcaggatgacataggcttggtttctctttgtgaa
gatgaacctagttcttcaggtgaattaaactactatgaccttgtcagaactgaaattgca
gaagaaagacagtatctacggaaactaaatatgatcataaaagtgtttcgaaaggttttt
ctttctgacagaaagctgtttaaatcttctgatattgaaaaggttttcagtaacatttta
gatatacatgaattgaccgtgaaacttttaggtctaattgaagacacagttgaaatgact
gatgaaagcagccctcatcccttagctggaagctgttttgaagatttgacagaggaacaa
gcatttgatccttatgaaacattatcacaggatattctttcaccaaaatttaatgaacat
ttcagtaagttgatggccatacctgcagtggctctacagtttcagtccattgctgatggt
tttaaagaggcagtttattatgtccttccacaccttatgctggtgccagtatatcattgt
tggcactattttgaattattaaagcaattgaaagcatgtagtgaagagcatgaagacaga
gaatgtttgaaccaagctattactgctctcatgaatctccaaggtagtttggaccgaatt
tacaagcaatattcacctagatgctgacctggggatcctgtttaccctttttataatcat
caattaagaagcaagcacctggctattaaaaaaatgaatgaaattcagaaaaacatagat
ggatgggaaggcaaagatattggacagtgttgtaatgaatttattatggaaggtccattg
acaagaattggtgccaaacacgaatggcatatttttctctttgatggctgcttaatgatt
agctgcaaacccaatcatagccagtcacaccttccaggataccatagtacagaatacaga
ttaaaagaaaaatttgtcatgaggaaaatacaaatatgtgataaagaagatacttgtgag
tgcaaacatgcttttgaattagtatccaaagatgaaaacagcataatatttgctgctagg
tctgctgaagagaaaaataattggatggcagcacttatttctcttcattatcgtagtact
ctagatcaaatgctagattcagtattactgaaggaagaaaatgaacaaccacttaaatta
ccgagtcctgaagtgtatcgttttgtggtaaaagactctngagaaaacattgtttttgaa
gacaacttgcaaagcagaagtggaatccccattattaaaggaggagctgtggtgaaatta
attgaaaggttaacgtatcacatgtatgcagatcccaattttgttcgcacttttcttact
atgtatcgttcattttgtaaaccacaggaattgctaagcttactgattgaacgatttgaa
attccagagccagaacctactgaagcagataaattggcagtagagaaaggcgagcagccg
atcagtgcagaccttaaaaggtttcacaaggaatacgtccaaccagtacaacttaggatc
ttaaatgtgtttcggcactgggtcgaacaccattattatcactttgaaagagacttggag
ttgcttgaaagactagaatccttcatttcaagtgtaagagggaaagctatgaagaaatgg
gtagagtcaattgctaagatcatcaagaggaagaaacaagctcaggcaaatggaataagc
cataatattacctttcaaagtctgccaccaccaaccgaatggcatatcagcagaccagga
cagtttgaaacgtttgatctcatgacacttcatccaatagaaattgcacgtcagctgaca
cttttggaatctgatctctacagcaaagttcaaccttctgaacttgtagggcatgtatgg
accaaagaagataaagaaatagattctccaaatttattaaaaatgattcaccacaccaca
aatctcactctctggtttgaaaagtgcattgtggaagcagaaaattttgaggaacgggtg
gcagtactaagtagaattatagaaattctgcaagtttttcaagatttgaataatttcaat
ggtgtattagagattgtcagtgcagtaaattcagtatcagtctatagactagatcatacc
tctgaggaaagaaaaaggaaaattttggatgaagctgtggaattaagtcaagatcattaa
aaaaaatatctagtgaaacttaagtcaatcaatccaccttgtgtgcctttttttggaata
tatttaacaaatattctgaagactgaagaagggaataatgattttttaaaaaagaaaggg
aaagatttaatcaatttcagtaagaggaggaaaaggaggaaagtacctgaaattactgga
gaaattcagcaatatcagaatcaaccttactgtttatggatagaaccagaaatgaggagg
ttctttgaaaaccttaaccccatgggaaatgcttctgaaaaagagtttacagattatttg
ttcaacaagtcactagaaattgaacccggaaactccaaacagccacctcgatttcctagg
aactcaactttctctttaaaatctcctggaataaggcctaatacaggccgacatggctct
acctcaggtactttatggggtcgtccaacaccattagaaagagaactgtgtaaaataagc
tttagtcggattgctgaaacagagcttgaatcaacagtgtcagcaccaacctctccaaat
acaccatctactccaccagtatctgcttcttcagaccttagtgtgtttttagatgtggat
ctcagcagttcctgtggaagcaatagcatctttgctccagtcctcttgcctcattcagag
tctttctttagttcgtgtggtagtttacataaactaagtgaagagccactgattcctcct
gcactttctcctcgaaacaaatttgatcatgatgcttcaaattccaagggaactatgaaa
tctgatgatgacccccctgctattctgccaagacagcctcctcctccaaaggtaaaaccc
agagttcctgtgcctactggtgcatttgacgggcctctgcatagtccaccgccgccgccg
ccgagagatccttttcccaatacccctccaccagttccccttcggcctccagaacacttc
ataaactgtccgtttactcttcaaccacctccactgggacatcttcacagagatccagac
tggttcagagatgttagtacgtgtccaaattctccaaacactcctcttagcacaccctct
ccaagggtaccacgttgatgctatgtgctcagttctagtcaaaataatcttgctcatcct
caagctccccctgttccaccaaggcaggattcaagccctcacctaccaaaactgccacca
aagacttacaaacgggagctttcgcaccccccattgtatagactgcctttgctagaaaat
gcagaaactcctcaatga
Physeter catodon (sperm whale): 102991639
Help
Entry
102991639 CDS
T06011
Gene name
SOS1
Definition
(RefSeq) son of sevenless homolog 1 isoform X1
KO
K03099
son of sevenless
Organism
pcad
Physeter catodon (sperm whale)
Pathway
pcad01521
EGFR tyrosine kinase inhibitor resistance
pcad01522
Endocrine resistance
pcad04010
MAPK signaling pathway
pcad04012
ErbB signaling pathway
pcad04014
Ras signaling pathway
pcad04062
Chemokine signaling pathway
pcad04068
FoxO signaling pathway
pcad04072
Phospholipase D signaling pathway
pcad04150
mTOR signaling pathway
pcad04151
PI3K-Akt signaling pathway
pcad04510
Focal adhesion
pcad04540
Gap junction
pcad04630
JAK-STAT signaling pathway
pcad04650
Natural killer cell mediated cytotoxicity
pcad04660
T cell receptor signaling pathway
pcad04662
B cell receptor signaling pathway
pcad04664
Fc epsilon RI signaling pathway
pcad04714
Thermogenesis
pcad04722
Neurotrophin signaling pathway
pcad04810
Regulation of actin cytoskeleton
pcad04910
Insulin signaling pathway
pcad04912
GnRH signaling pathway
pcad04915
Estrogen signaling pathway
pcad04917
Prolactin signaling pathway
pcad04926
Relaxin signaling pathway
pcad04935
Growth hormone synthesis, secretion and action
pcad05034
Alcoholism
pcad05160
Hepatitis C
pcad05161
Hepatitis B
pcad05163
Human cytomegalovirus infection
pcad05165
Human papillomavirus infection
pcad05200
Pathways in cancer
pcad05205
Proteoglycans in cancer
pcad05206
MicroRNAs in cancer
pcad05210
Colorectal cancer
pcad05211
Renal cell carcinoma
pcad05213
Endometrial cancer
pcad05214
Glioma
pcad05215
Prostate cancer
pcad05220
Chronic myeloid leukemia
pcad05221
Acute myeloid leukemia
pcad05223
Non-small cell lung cancer
pcad05224
Breast cancer
pcad05225
Hepatocellular carcinoma
pcad05226
Gastric cancer
pcad05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102991639 (SOS1)
04012 ErbB signaling pathway
102991639 (SOS1)
04014 Ras signaling pathway
102991639 (SOS1)
04630 JAK-STAT signaling pathway
102991639 (SOS1)
04068 FoxO signaling pathway
102991639 (SOS1)
04072 Phospholipase D signaling pathway
102991639 (SOS1)
04151 PI3K-Akt signaling pathway
102991639 (SOS1)
04150 mTOR signaling pathway
102991639 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
102991639 (SOS1)
04540 Gap junction
102991639 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102991639 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
102991639 (SOS1)
04660 T cell receptor signaling pathway
102991639 (SOS1)
04662 B cell receptor signaling pathway
102991639 (SOS1)
04664 Fc epsilon RI signaling pathway
102991639 (SOS1)
04062 Chemokine signaling pathway
102991639 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
102991639 (SOS1)
04912 GnRH signaling pathway
102991639 (SOS1)
04915 Estrogen signaling pathway
102991639 (SOS1)
04917 Prolactin signaling pathway
102991639 (SOS1)
04926 Relaxin signaling pathway
102991639 (SOS1)
04935 Growth hormone synthesis, secretion and action
102991639 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
102991639 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
102991639 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102991639 (SOS1)
05206 MicroRNAs in cancer
102991639 (SOS1)
05205 Proteoglycans in cancer
102991639 (SOS1)
05231 Choline metabolism in cancer
102991639 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
102991639 (SOS1)
05225 Hepatocellular carcinoma
102991639 (SOS1)
05226 Gastric cancer
102991639 (SOS1)
05214 Glioma
102991639 (SOS1)
05221 Acute myeloid leukemia
102991639 (SOS1)
05220 Chronic myeloid leukemia
102991639 (SOS1)
05211 Renal cell carcinoma
102991639 (SOS1)
05215 Prostate cancer
102991639 (SOS1)
05213 Endometrial cancer
102991639 (SOS1)
05224 Breast cancer
102991639 (SOS1)
05223 Non-small cell lung cancer
102991639 (SOS1)
09165 Substance dependence
05034 Alcoholism
102991639 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
102991639 (SOS1)
05160 Hepatitis C
102991639 (SOS1)
05163 Human cytomegalovirus infection
102991639 (SOS1)
05165 Human papillomavirus infection
102991639 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102991639 (SOS1)
01522 Endocrine resistance
102991639 (SOS1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04990 Domain-containing proteins not elsewhere classified [BR:
pcad04990
]
102991639 (SOS1)
Domain-containing proteins not elsewhere classified [BR:
pcad04990
]
Pleckstrin homology (PH) domain-containing proteins
Dbl-Like RhoGEF family proteins
102991639 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
Histone
PH
PH_19
PH_10
IQ_SEC7_PH
PH_13
Motif
Other DBs
NCBI-GeneID:
102991639
NCBI-ProteinID:
XP_023974332
UniProt:
A0A2Y9SAH3
LinkDB
All DBs
Position
12
AA seq
1333 aa
AA seq
DB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENVQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDTIFIQVTLPHGPRSASVSSISL
TKSTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSVSD
RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHSNAFFPNSPSPFTPPP
PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPIPPRQSTSQHIPKLPPKTYKREHTHPSMH
RDGPPLLENAHSS
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccgtacgagtttttcagcgaggagaacgcgcccaagtggcgg
gggctgctggtgcctgcgctgaaaaaggttcaggggcaagttcatcctactcttgagtct
agtgatgatgctcttcagtatgttgaagaattaattttgcagttattaaatatgctatgc
caagctcagccccgaagtgcttcagatgtagaggaacgtgttcaaaaaagtttccctcat
ccaattgataagtgggcaatagctgatgcccagtcggctattgaaaagaggaagcgaaga
aaccctttatctctcccagtagaaaaaattcatcctttgttaaaggaggtcctaggttat
aaaattgaccaccaggtttctgtttacatagtagcagtattagaatacatttctgcagac
attttaaagctggtggggaattatgtgcgaaatatacggcattatgaaattacaaaacaa
gatattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta
gaagatataaatatattatctttaactgatgaagagccttccacctcaggagagcaaact
tattatgatttggtaaaagcatttatggcagaaattcgacaatacataagggaacttaat
ttaattataaaagtttttagagagccctttgtctccaattcaaaattgttttcagctaat
gatgtagaaaatatatttagtcgtatagtggatatacatgaacttagtgtaaagttactg
ggccatatagaagatactgtagaaatgacagatgaaggcagtccccatccattagtagga
agttgctttgaagacttagcagaggaactggcatttgatccatatgaatcatatgctcga
gatattttacgacctggttttcatgatcgtttccttagtcagttatcaaagcctggagcg
gcactctatttgcagtcaataggcgaaggtttcaaagaagctgttcagtatgttttaccc
aggctacttctagcccctgtttaccactgtctacattactttgaacttctgaagcagtta
gaagaaaagagtgaagatcaagaagacaaggaatgtttgaaacaagcaataacagctttg
cttaatgttcagagtggtatggaaaaaatctgttctaaaagtcttgcaaaacgaagactg
agtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaacgagattcagaagaatattgatggttgggagggaaaagacattggacagtgt
tgcaatgagtttataatggaaggaactcttacacgtgtaggagccaaacatgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcagccaagactt
cctggtgctagcaatgcagaatatcgtcttaaagaaaagttttttatgagaaaggtacaa
attaatgacaaggatgacaccaatgagtacaagcatgcttttgaaataattttaaaagat
gaaaatagcgttatattttctgccaagtcagctgaagagaaaaacaattggatggcagca
ttaatatctttacagtaccggagtacactggaaaggatgcttgatgtgacaatgctacag
gaagaaaaggaggagcagatgaggctccctagtgctgatgtttatagatttgcagagcct
gactctgaagaaaatatcatatttgaagaaaacgtgcagcccaaagctggaattccaatt
atcaaagcaggaactgttattaaacttatagagaggctcacataccatatgtacgcagat
cccaattttgttcggacatttcttacaacatatagatccttttgtaaacctcaagaacta
ctgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
atagctatagagaatggagatcagcccttgagtgcagaactaaaaaggtttagaaaagaa
tatatacagcctgtacaactgcgagtattaaatgtatgtcggcactgggtagagcaccac
ttctacgattttgaaagagatgcagatcttttgcagcgaatggaggaatttattggaaca
gtaagaggtaaagcaatgaaaaagtgggttgaatccatcactaaaataatccaaaggaaa
aaaattgcaagagacaatggaccaggtcataatattacatttcagagttcgcctcccaca
gttgagtggcatataagcagacctgggcacatagagacttttgacctgctcaccttacac
ccaatagaaattgctcgacaactcactttacttgaatcagatctatatcgagctgtacag
ccatcagaattagttggaagtgtgtggacaaaggaagacaaagaaattaattctcctaat
cttctgaaaatgatccggcataccactaatctcactctgtggtttgagaaatgtattgta
gaaactgaaaacttagaagaaagagtagctgtggtgagtcgaataattgagattctgcaa
gtctttcaagagctgaacaacttcaatggtgtccttgaggttgtcagtgctatgaactca
tcacctgtatacagactagaccacacgtttgagcaaataccaagtcgccaaaagaaaatt
ttagaagaagctcatgaactaagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttggaatttatctaactaatatcttgaaaaca
gaagaaggcaaccctgaggtcctaaaaaggcatgggaaagagcttataaactttagcaaa
aggaggaaagtagcagaaataacaggcgagatccagcagtaccaaaatcagccttattgt
ttacgagtagaatcagatatcaaaaggttctttgaaaacttgaatccaatgggaaatagt
atggaaaaagaatttacagattatcttttcaacaaatccctagaaatagaaccacgaaac
cctaagcctctcccaagatttccaaaaaaatatagctatcccctaaaatctcctggtgtt
cgtccatcaaacccaagaccaggtactatgagacatcccacacctctgcagcaagagcca
aggaaaattagttatagtaggatccctgaaagtgaaacagaaagtacagcatctgcacca
aattctccaagaacaccgttaacacctcctcctgcttctggtgcttctagtaccacagat
gtttgcagcgtatttgattctgatcattcaagcccttttcactcaagcagcgataccatc
tttatccaagttacactgccccatggcccaagatctgcttcagtatcatctataagttta
accaagagcactgatgaagtgcctgtcccccctcctgttcctccacgaagacgaccagaa
tctgccccagcggaatcttcgccatctaagatcatgtctaagcatttggacagcccccca
gcaattcctcctaggcaacccacatcaaaagcctattcaccacgatattcagtatcagac
cggacctctatatcagatcctcctgaaagccctcccttattacctccacgagaacctgtg
aggacacctgatgttttctcaagctcaccactacatctccaacctccccctttgggcaaa
aaaagtgaccatagtaatgccttcttcccaaacagcccttccccctttacaccacctcct
cctcaaacaccttctcctcatggcacaagaaggcatctgccatcaccaccactgacacaa
gaagtggaccttcattccattgctgggccgcctattcctccacgacaaagcacttctcaa
catatccctaaactccctccaaaaacttacaaaagggagcatacacacccatccatgcac
agagatggaccaccactgttggagaatgcccattcttcctga
DBGET
integrated database retrieval system
