Physeter catodon (sperm whale): 102982229
Help
Entry
102982229 CDS
T06011
Gene name
PTK2
Definition
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
pcad
Physeter catodon (sperm whale)
Pathway
pcad01522
Endocrine resistance
pcad04012
ErbB signaling pathway
pcad04062
Chemokine signaling pathway
pcad04151
PI3K-Akt signaling pathway
pcad04360
Axon guidance
pcad04370
VEGF signaling pathway
pcad04510
Focal adhesion
pcad04670
Leukocyte transendothelial migration
pcad04810
Regulation of actin cytoskeleton
pcad04935
Growth hormone synthesis, secretion and action
pcad05100
Bacterial invasion of epithelial cells
pcad05135
Yersinia infection
pcad05146
Amoebiasis
pcad05163
Human cytomegalovirus infection
pcad05165
Human papillomavirus infection
pcad05170
Human immunodeficiency virus 1 infection
pcad05200
Pathways in cancer
pcad05202
Transcriptional misregulation in cancer
pcad05205
Proteoglycans in cancer
pcad05222
Small cell lung cancer
pcad05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
102982229 (PTK2)
04370 VEGF signaling pathway
102982229 (PTK2)
04151 PI3K-Akt signaling pathway
102982229 (PTK2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
102982229 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102982229 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
102982229 (PTK2)
04062 Chemokine signaling pathway
102982229 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
102982229 (PTK2)
09158 Development and regeneration
04360 Axon guidance
102982229 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102982229 (PTK2)
05202 Transcriptional misregulation in cancer
102982229 (PTK2)
05205 Proteoglycans in cancer
102982229 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
102982229 (PTK2)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
102982229 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
102982229 (PTK2)
05100 Bacterial invasion of epithelial cells
102982229 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
102982229 (PTK2)
05163 Human cytomegalovirus infection
102982229 (PTK2)
05165 Human papillomavirus infection
102982229 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
102982229 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
102982229 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcad01001
]
102982229 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
pcad01009
]
102982229 (PTK2)
Enzymes [BR:
pcad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
102982229 (PTK2)
Protein kinases [BR:
pcad01001
]
Non-receptor tyrosine kinases
FAK family
102982229 (PTK2)
Protein phosphatases and associated proteins [BR:
pcad01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
102982229 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_N_2
FERM_M
Kinase-like
FERM_F2
Motif
Other DBs
NCBI-GeneID:
102982229
NCBI-ProteinID:
XP_028356130
UniProt:
A0A455C474
LinkDB
All DBs
Position
15
AA seq
1132 aa
AA seq
DB search
MFLLPAGNGARVEEHRADGAGAGRQEYDRYLASSKIMAAAYLDPNLNHTPNSSTKTHLGT
GVERSPGAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYG
FRLSHLRSEEVHWLHLDMGVSNVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTL
NFFYQQVKSDYMLEIADQVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLK
RFFPRSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGS
SWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDRKGTLQLKIAGAP
EPLTVTAPSLTIAENMADLIDGYCRLVHGATQSFIIRPQKEGERALPSIPKLANSEKQGV
RTHAVSVSGVSHCQHKVKKARRFLPLVFCSHEPPSADEISGDETDDYAEIIDEEDTYTMP
SKSYGIDEARDYEIQRERIELGRCIGEGQFGDVHQGAYTSPENPALAVAIKTCKNCTSDS
VREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASL
ILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGK
LPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPM
PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKVQQEERMRMESRRQVTVSW
DSGGSDEAPPKPSRPGYPSPRSSEGFHPSPQHMVQTNHYQVSGYPGSHGITAVAGSIYPG
QASLLDQTDSWNHRPQEISMWQPNVEDSATLDLRGIGQVLPTHLMEERLIRQQQEMEEDQ
RWLEKEERFLKPDVRLSRGSIDREDGGPQGPTGNQHIYQPVGKPDPAAPPKKPPRPGAPG
HLSSLASLGSPGDNYNEGVKPWRLQPQEISPPPTANLDRSNDRVYENVTGLVRAVIEMSS
KIQPAPPEEYVPMVKEVGLALRTLLATVDETIPVLPASTHREIEMAQKLLNSDLGELINK
MKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKALGQTRPH
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atgttcctcctgcctgctgggaacggtgcccgggttgaagaacatagggcagatggggca
ggagcagggagacaagaatatgacagatacctagcatctagcaaaataatggcagctgct
taccttgacccaaacttgaatcacacaccgaattcaagtaccaagactcacctgggtacc
ggtgtggaacgttcccctggggccatggagcgagtgttgaaggtctttcattattttgaa
agcaacagtgagccaaccacttgggccagtattatcaggcatggagatgctactgacgtc
aggggcatcattcagaagatagtggacagtcacaaagtaaagcacgtggcctgctatgga
tttcgcctcagtcacctgcggtcagaggaggttcactggctccatttggatatgggtgtc
tccaatgtgagggagaagtatgaacttgcacacccaccagaggagtggaaatacgaattg
agaattcgttatttgccaaaaggatttctaaaccagtttactgaagacaagccaactctg
aatttcttctatcaacaggtgaagagcgattatatgttggagatcgctgatcaagtggac
caggacattgctttgaagttgggttgtctagaaatacggcggtcgtactgggagatgcgg
ggcaacgccctggagaagaagtctaactatgaagtattagaaaaagatgttggtttgaag
cgattttttcctaggagtttactggattcagtcaaggccaaaacactaagaaaattgatc
caacaaacatttagacagtttgccaaccttaatagagaagaaagtattttgaaattcttt
gagatcctctccccagtgtacagatttgataaagaatgcttcaagtgtgcccttggttca
agctggattatttcggtggagctggcgattggccccgaagaaggaatcagttacctcaca
gacaagggctgcaaccccacacacctggccgacttcaatcaagtgcagaccattcagtat
tcaaacagcgaagacaaggacaggaaaggaacgctgcagctgaagattgcaggagcgcct
gagcctctgacggtgacagcaccgtccctgaccattgccgagaacatggccgacctgata
gatgggtactgccggctggtgcacggggccacgcagtctttcatcatcaggccccagaaa
gaaggtgaacgggctttgccatcgataccaaagctggccaacagcgagaagcagggcgtt
cggacccacgccgtctccgtgtcaggagtcagtcactgccaacataaagttaagaaagct
aggcgctttctccctttggtcttctgttcccacgaacctccttctgcggatgaaattagt
ggggacgaaacagatgactatgctgagattatcgacgaagaagatacctacaccatgccc
tcgaaaagctatggaatagatgaagccagggactatgagattcagagagaaagaatagaa
ctcggacggtgcatcggagagggccagtttggagacgtgcaccaaggcgcttacacgagc
ccggagaatccagctctggcggttgcaattaaaacatgtaaaaactgtacttcggacagc
gtgagagagaaattccttcaagaagccttaacgatgcgtcagtttgaccaccctcacatt
gtgaagctgattggagtcatcacagagaaccccgtctggatcatcatggagctgtgcacg
ctcggagagctgaggtcatttctgcaagtaaggaaatacagtttggatctagcatctctg
atcctctatgcctatcagcttagcacagcccttgcgtacctagagagcaaaagatttgtg
cacagggacattgctgctcggaatgttctggtgtcctcaaacgattgtgtaaaattagga
gactttggattatcccgatatatggaagacagtacttactacaaagcttccaaaggaaaa
ttgcctattaaatggatggctccagagtcaatcaattttcgccgttttacctcagctagt
gacgtatggatgtttggtgtgtgtatgtgggagatactgatgcacggtgtgaagcccttt
caaggtgtgaagaacaatgatgtgatcggtcgcattgagaacggggagaggttgcccatg
cctccgaactgccctcccactctctacagcctcatgaccaagtgctgggcctacgatccc
agccggcggccccgcttcactgagctcaaagctcagctcagcacaatcctggaggaagag
aaggtccagcaagaagaacggatgaggatggagtccagaaggcaggtcacagtgtcctgg
gactccggagggtccgacgaagcaccacccaagcccagcagacctggttatcctagtccg
aggtccagcgaagggtttcatcccagcccacagcacatggtacagaccaatcactaccag
gtctctggctaccctggctcacatggaatcacagccgtggctggcagcatctacccaggt
caggcatctcttttggaccaaacagattcgtggaatcacagaccacaggagatatcgatg
tggcagcccaacgtggaggactctgcaacactggacctgcgcggcatcgggcaggtgttg
ccgacccacctgatggaggagcggctgatccggcagcagcaggagatggaagaggatcag
cgctggctggagaaggaggagaggtttctgaaacctgacgtgcggctctctcgaggcagc
atcgacagggaggatggaggtcctcagggcccgactggaaaccagcacatatatcagcct
gtgggcaaaccagatcctgcagctccaccaaagaaaccaccgcgtcccggagccccgggg
cacctgagcagcctagccagcctcggcagccccggggacaattacaacgagggtgtcaag
ccgtggaggcttcagccccaggaaatcagcccccctcccactgccaacctggaccggtcc
aatgacagggtgtacgagaacgtgacgggcctggtgagggcggtcatcgagatgtccagc
aagatccagccagccccgccagaggagtatgtccccatggtgaaggaagtcggcttggcc
ctgaggacgctgttggccaccgtggatgagaccattcccgtcctgcccgccagcacccac
cgagagattgagatggcccagaagctgctgaactccgacctgggggagctcatcaacaag
atgaagctggcccagcagtatgtcatgaccagcctgcagcaggagtacaagaagcagatg
ctgacggctgcacacgccctggccgtggacgccaagaacctgcttgatgtcatcgaccag
gccagactgaaggccctggggcagacgaggccgcactga
DBGET
integrated database retrieval system
