Physeter catodon (sperm whale): 102983752
Help
Entry
102983752 CDS
T06011
Gene name
EML4
Definition
(RefSeq) echinoderm microtubule-associated protein-like 4 isoform X1
KO
K15420
echinoderm microtubule-associated protein-like 4
Organism
pcad
Physeter catodon (sperm whale)
Pathway
pcad05200
Pathways in cancer
pcad05223
Non-small cell lung cancer
pcad05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102983752 (EML4)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102983752 (EML4)
09162 Cancer: specific types
05223 Non-small cell lung cancer
102983752 (EML4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
pcad04812
]
102983752 (EML4)
Cytoskeleton proteins [BR:
pcad04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
EMAP
102983752 (EML4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HELP
WD40
ANAPC4_WD40
Ribosomal_S7
SlyX
Motif
Other DBs
NCBI-GeneID:
102983752
NCBI-ProteinID:
XP_007112246
UniProt:
A0A2Y9F0V3
LinkDB
All DBs
Position
12
AA seq
1006 aa
AA seq
DB search
MEDRLPGLASVCASSTLRSFCTDDSISAASTSDVQDRLSALELRVQQQEDEITVLKAALA
DVLRRLTISEDHVASVKKSVPSKGQPGIREAISMSCITNGSGANRKPSHTSSVSIARKET
LSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQTHRQTQESKNS
TPTKSIKRPPTAEKSHNSWENSDDSRNKLLRAVSTSKLISKVIKNADKHKDVIINQAKMS
TREKNSQEGEYVKMFMRGRPITMFIPSDVDNYDDIRTELPPEKLKLEWVYGYRGKDCRAN
VYLLPTGEIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAIHPDKIRIATGQIAGVDKD
GRPLQPHVRVWDSVSLSTLQIIGLGTFERGVGCLDFSKADSGVHLCVIDDSNEHMLTVWD
WQKKSKGAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGNSLTRKQGVFGKYEK
PKFVQCLTFLGNGDVLTGDSGGVILIWSKTTVEPTPGKGPKGVYQISRQIKAHDGSVFTL
CQMRNGMLLTGGGKDRKIILWDHDLNPEREIEVPDQYGTIRAVAEGKADQFLVGTSRNFI
LRGTFNDGFQIEVQGHTDELWGLATHPFKDLLLTCAQDRQVCMWNSVEHRLEWTRLVDEP
GHCADFHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSLDGTFLAVGSH
DNFIYLYVVSENGRKYSRHGKCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPNGCK
LIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNRKVIAVADDFCKVHL
FQYPCSKAKAPSHKYSAHSSHVTNVSFTHNDSHLISTGGKDMSIIQWKLVEKLSLPQNEV
VADTALTKAPVSSIESVMQSDAPAPPPSQPLNETAEEESRISSSPTLLENSLEQTVGPSA
DHSEERSEGGSEDLGEPVYEEPARGMSDERSEGALPGDQQDPSPLS
NT seq
3021 nt
NT seq
+upstream
nt +downstream
nt
atggaagaccgcttgcctggtctcgcttcagtgtgtgcttcctctacacttaggagcttc
tgcactgatgatagtatttctgctgcaagtacttctgatgttcaagatcgcctctcagcc
cttgagttacgagttcaacaacaagaagatgaaatcactgtgctaaaggcagcattggct
gatgttttgaggcgtcttacaatctctgaagatcatgtagcctcagtgaaaaaatcagtc
ccaagtaaaggccagccaggcattcgagaagctatttccatgtcctgtataaccaatggg
agtggtgcaaacagaaaaccaagtcacaccagctctgtttcaatcgcaagaaaagaaact
ctttcatctgctgctaaaagtggtacagaaaaaaagaaagaaaaaccacaaggacagaga
gaaaaaaaagaggaatctcactctaatgatcaaagtccacaaattcgagcatcaccttct
ccccagccctcttcacagcctctccaaacacacagacaaactcaagaaagcaagaattct
actcccaccaaaagcataaaacgaccaccaacagctgaaaagtcacataattcatgggaa
aattcagacgatagccgtaataaattactgagggcagtttcaacatcaaaattaatatca
aaagttataaaaaatgcagacaagcataaagatgtcatcatcaaccaagcaaaaatgtca
acccgtgaaaaaaacagccaagaaggagaatatgttaaaatgtttatgcgaggtcgacca
attacaatgttcattccttctgatgttgacaactatgatgacatcagaacagagctgcct
cctgagaagctcaaactggagtgggtatatggttatcgaggaaaggactgtcgagctaat
gtttaccttcttcctaccggggaaatcgtttatttcatagcgtcagtagtagtactattt
aattatgaggagagaactcaacgacactacctgggtcatacagactgtgtgaaatgcctt
gctatacatcctgacaaaattaggattgcaactggacagatagctggagtggataaggat
ggaaggcccctgcagccccatgtcagagtgtgggattcagttagtctgtctacactgcaa
attattggacttggaacttttgagcgtggagtaggatgcctggatttttcaaaagcagat
tcaggtgttcatttatgtgtcatcgatgactccaatgagcatatgcttactgtatgggat
tggcagaagaaatcaaaaggagcagaaataaagacaacaaatgaagttgttttggctgtg
gaattccatccaacagatgcaaataccataataacctgtggtaaatctcacatttttttc
tggacctggagtggcaattcactaacaagaaaacagggagtttttgggaaatacgaaaaa
ccaaaatttgtgcagtgtttgacattcttggggaatggagatgttcttactggagactca
ggtggagtcatacttatatggagcaaaactactgtagaacccacacctgggaaagggcct
aaaggtgtttatcagatcagcagacaaatcaaagctcatgatggcagtgtgttcacactt
tgtcagatgagaaatggtatgttattaactggaggcgggaaagacagaaaaataattctg
tgggatcatgatctgaatcctgaaagagaaatagaggttcctgatcagtatggaacaatc
agagctgtagcagaaggaaaggcagatcaatttttggtaggcacatcacgaaactttatt
ttacggggaacatttaatgatggcttccaaatagaagtacagggtcatactgatgagctt
tggggtcttgccacacatcccttcaaagatttgctcttgacatgtgctcaggacagacag
gtgtgcatgtggaactcggtggaacacaggctggaatggaccaggctcgtagatgaacca
ggacactgtgcagattttcatccaagtggcacagtggtggccataggaacgcactcaggc
aggtggtttgttctggatgcagaaaccagagatctagtttctatccacacagacgggaat
gaacagctctctgtgatgcgctactcattagatggcaccttcctggctgtgggatctcat
gacaactttatttacctctatgtggtctcagaaaatggaagaaagtatagcagacatgga
aagtgcactggacattccagctatatcacacaccttgactggtctccagacaacaagtac
ataatgtctaactcgggagactatgagattctgtactgggacattccaaatggctgcaaa
ctaattaggaatcgatcagactgtaaggacatcgattggacgacatacacctgtgtgcta
ggctttcaagtctttggtgtctggccagaaggatctgatgggacagatatcaatgcactg
gtgcggtcccacaatagaaaggtgatagctgttgctgatgacttctgcaaagtccacctg
tttcagtatccctgctccaaagcaaaggctcccagtcacaagtacagtgcccacagcagc
catgtcaccaatgtcagttttactcataatgacagtcacctgatttcaactggtggaaaa
gacatgagcatcattcagtggaaacttgtggaaaagttatctttgcctcagaatgaggtt
gtagcggatactgcgctcaccaaagcccccgtctcttccattgaaagtgtcatgcagtct
gatgctcccgcaccacctccttcccagcccttaaatgagacagctgaagaagaaagcagg
ataagcagttctcccacacttctggagaacagcctggaacagactgtggggcccagcgca
gaccacagtgaggagcggagtgaggggggcagcgaagacctcggtgagcctgtttacgaa
gagccagcccgcgggatgagcgatgagcggagcgaaggcgccctccccggggaccagcag
gacccttcacccctgtcctaa
Physeter catodon (sperm whale): 102988118
Help
Entry
102988118 CDS
T06011
Gene name
ALK
Definition
(RefSeq) ALK tyrosine kinase receptor
KO
K05119
anaplastic lymphoma kinase [EC:
2.7.10.1
]
Organism
pcad
Physeter catodon (sperm whale)
Pathway
pcad05200
Pathways in cancer
pcad05223
Non-small cell lung cancer
pcad05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102988118 (ALK)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102988118 (ALK)
09162 Cancer: specific types
05223 Non-small cell lung cancer
102988118 (ALK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcad01001
]
102988118 (ALK)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pcad04090
]
102988118 (ALK)
Enzymes [BR:
pcad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102988118 (ALK)
Protein kinases [BR:
pcad01001
]
Receptor tyrosine kinases (RTK)
ALK family
102988118 (ALK)
CD molecules [BR:
pcad04090
]
Proteins
102988118 (ALK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
MAM
Pkinase
Gly_rich
Ldl_recept_a
Nup96
Motif
Other DBs
NCBI-GeneID:
102988118
NCBI-ProteinID:
XP_028352394
UniProt:
A0A455BTT6
LinkDB
All DBs
Position
12
AA seq
1154 aa
AA seq
DB search
MGAIGLLWLLLLLSPAASGSGSGTETGQRVGSPAMGSALQPREPLSYSRLQRKSLAVDFV
VPSLFRVYARDLLLPPPSPSETMAGRLEARGSLALDCAPLLRLVGPPPGASSPAPARART
LSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPPEEATAGLLQFNLTELFSWWIRYGE
GRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLFQIFATGTGHSSLELPTNLPSLPPDS
FAWNLTWIMKDSFPFLSHRSRYGLECSFDFPCELEYSPPLHNLGNQSWSWRRVPSEEASQ
MDLLDGPEEEHSKEMPRGAFLLLNTSVNSKHTILSPWMESSSEHCRLAVSVHRRPQPSGR
YVAQLLPHSEAGREIPLVPTPGKHGWTVLQGRIGRPENPFRVALEYISSGNRSLSAVDFF
ALKNCSEGTSPGSKMALQSSFTCWNGTVLQLGQACDFHRDCAQGEDEGQLCGKLPAGFYC
NFEDGFCGWTQSSLSPHTPQWQVRTLKDARFQDHQGHALLLSTTDAPTSESATVTSATFP
APMKNSPCELRMSWLIRGVLQGNVSLVLVENKTGKEQSRMIWHVATMEGLSLWQWTALPL
LDVADRFWLQIVAWWGQGSRATVAFNNISISLDCYLTIRGEDKMPQNTAPKSRNLFEGNP
NKEPKPWENTPKENPIFDPTVHWLFTTCGASGPHGPTQAQCNNAYRNSNLSVVVGSEGPL
KGIQTWKVPATDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKDDVLYILVGQQGE
DACPSPSDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAF
MEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRI
MTQCWQHQPEDRPNFATILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPMRPKDPEGI
PPLLVSAPPATRDEGREPAARTALPSASSGKAGKKPVAAEASARGARAPAVKGGHVNMAF
SQSNPPSELHQVQGSRNKPTSLWNPTYGSWFTEKPTKKSNPPAKKEQRDRGNLGGEGGCA
MPLPAAAGRRPGTSLLLEPSSLTASLRDVPLFRLRHFPCGTVHYGYQQQGFPPEAAAPGR
GRYEDPAAKSQPAP
NT seq
3465 nt
NT seq
+upstream
nt +downstream
nt
atgggagccatagggcttctgtggctgctgctgctgctttcaccggcagcctcaggctcc
gggagcgggaccgagaccggccagcgcgtgggctcaccagccatggggtcggcgctgcag
ccccgggagccgctcagctactcgcgcctgcagaggaagagcctggcggtggactttgtg
gtaccctctctctttcgcgtctatgctcgggacctgctgctgccgccgccgtccccttcg
gagacgatggccggccggctggaggcgcgcggctcgctggctcttgactgcgccccactg
cttaggctggtggggccaccacccggcgccagctctcccgccccggcccgggcacggacg
ctgtccagggtgctgaagggaggctcggttcgcaagctccggcgcgccaagcagctggtg
ctggagctgggagaggaggcgatccttgagggctgtgtagggcccccagaggaggcgact
gcggggctgctccagttcaacctcactgagctgttcagctggtggattcgctacggcgaa
ggacggctgaggatccgcctgatgcccgagaagaaggcgtcggaagtgggcagagaggga
aggctgtccgctgcgatccgcgcctcccagccccgccttctcttccagatcttcgcgacc
gggaccgggcatagctccttggagttaccaacaaacctgccttctcttcctcctgattct
tttgcctggaatctgacctggataatgaaagattccttcccattcctgtctcatcgcagc
cgatatggtctggagtgcagctttgacttcccctgtgagctggagtattcccctccacta
cacaaccttgggaaccagagctggtcctggcgccgtgtcccttccgaggaggcttcccag
atggacctgttggatggacccgaagaggagcactccaaggagatgcccagaggcgccttc
ctcctgctcaacacctcggtgaactccaagcacaccatcttgagtccatggatggagagc
agcagcgagcactgcaggctggccgtctcggtgcacaggcgcccgcagccctccgggagg
tacgtcgcccagctgctgccccacagtgaggctggaagagagatccccctggtacccact
ccaggaaagcatggttggactgtgctgcagggaagaattgggcgcccagagaacccgttc
cgagtggccctggaatacatctcgagtggaaaccgaagcttgtctgcagtggacttcttt
gccctgaagaactgcagcgaaggaacatccccgggctccaagatggccttgcagagttcc
ttcacttgctggaacgggacagtcctccagctcgggcaggcctgcgacttccaccgggac
tgtgcccagggagaagacgagggccagctgtgcggtaaactccctgctggtttttactgc
aacttcgaggatggattctgtggctggacccaaagctcactgtcaccccacacgccccag
tggcaagtcaggaccttaaaggatgcccggttccaggaccaccaaggccacgccctgttg
ctcagcaccactgatgcccccacctctgaaagtgctacggtgaccagcgctacgtttcct
gcaccgatgaagaactctccgtgcgagctccgaatgtcctggctcatccgtggagtcttg
cagggaaatgtctccttggtgctggtggagaacaaaaccgggaaggagcaaagcaggatg
atctggcatgttgccaccatggaaggcttgagcctgtggcagtggacggcgctgcctctc
cttgatgtggccgacaggttctggctgcagattgttgcgtggtggggacaaggatccaga
gccaccgtggctttcaacaatatctccatcagcctggactgctacctcaccattcgtggg
gaggacaagatgccgcagaatacagcacccaagtcaagaaatctgtttgagggaaaccca
aacaaggagccaaaaccctgggaaaacacaccaaaagagaaccccatctttgaccctaca
gttcactggctgttcaccacatgcggggccagtgggccccacggcccgacgcaggcccag
tgcaacaatgcctaccggaactccaacctgagtgtggtggtggggagcgagggccccctg
aagggcatccagacctggaaggtgccagccaccgacacctacagcatatcaggctacgga
gccgctggcgggaaaggcggtaagaacaccatgatgcgatcccacggcgtgtctgtgctg
ggcatcttcaacctggagaaggacgacgtgctgtacatcctggtcgggcagcagggggaa
gatgcctgccccagtcccagcgacattgctgccaggaactgcctcttgacctgtccaggc
cctggaagagtggccaagattggagacttcggaatggctcgagacatctaccgagcgagc
tactaccgaaagggaggctgtgcgatgctgccggtcaaatggatgcccccggaggccttc
atggaaggaatatttacttctaaaacagacacgtggtccttcggagtgcttctgtgggaa
atcttctctcttggatacatgccgtaccctagcaaaagcaaccaggaggttctggagttt
gtcaccagtggaggacggatggacccacctaagaactgccccgggcctgtataccggata
atgacccagtgctggcaacatcagcctgaagacaggcccaactttgccacaattttggag
aggattgaatactgcacccaggacccagatgtgatcaacactgctttgcccatagaatac
gggcccctcgtggaagaggaagagaaggtgcccatgaggcccaaggaccctgagggaatc
cctcctctgctggtctccgctcccccggccacgcgggatgagggccgcgagccggccgcc
cgcacggctctgccttccgcctcctcgggcaaagccggcaagaagcccgtggccgcagag
gcctctgcccgaggcgccagggcgccggccgtgaaggggggacacgttaacatggcattc
tctcagtccaacccgccctcggagctgcaccaagtccaggggtccagaaacaagcccacc
agcctatggaacccaacttacggctcctggttcacagagaaacccaccaaaaagagcaat
cctccggcgaagaaggagcagcgcgatagggggaacctgggcggcgagggcggctgtgcc
atgccgctccccgcggccgccggccgccggccgggcacctctctgctcctcgagccgtcc
tcgctgaccgccagcctgagggacgtgcctctgttcaggctgcgccacttcccgtgcggc
accgtccactacggctaccagcagcagggcttcccgcccgaggccgccgccccgggccgg
ggccgctacgaggaccccgcggccaagagccagcctgcgccctga
DBGET
integrated database retrieval system
