Physeter catodon (sperm whale): 102988182
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Entry
102988182 CDS
T06011
Gene name
JAK1
Definition
(RefSeq) tyrosine-protein kinase JAK1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
pcad
Physeter catodon (sperm whale)
Pathway
pcad01521
EGFR tyrosine kinase inhibitor resistance
pcad04151
PI3K-Akt signaling pathway
pcad04217
Necroptosis
pcad04380
Osteoclast differentiation
pcad04550
Signaling pathways regulating pluripotency of stem cells
pcad04621
NOD-like receptor signaling pathway
pcad04630
JAK-STAT signaling pathway
pcad04658
Th1 and Th2 cell differentiation
pcad04659
Th17 cell differentiation
pcad05140
Leishmaniasis
pcad05145
Toxoplasmosis
pcad05152
Tuberculosis
pcad05160
Hepatitis C
pcad05161
Hepatitis B
pcad05162
Measles
pcad05163
Human cytomegalovirus infection
pcad05164
Influenza A
pcad05165
Human papillomavirus infection
pcad05166
Human T-cell leukemia virus 1 infection
pcad05167
Kaposi sarcoma-associated herpesvirus infection
pcad05168
Herpes simplex virus 1 infection
pcad05169
Epstein-Barr virus infection
pcad05171
Coronavirus disease - COVID-19
pcad05200
Pathways in cancer
pcad05203
Viral carcinogenesis
pcad05212
Pancreatic cancer
pcad05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
102988182 (JAK1)
04151 PI3K-Akt signaling pathway
102988182 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
102988182 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
102988182 (JAK1)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
102988182 (JAK1)
04658 Th1 and Th2 cell differentiation
102988182 (JAK1)
04659 Th17 cell differentiation
102988182 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
102988182 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102988182 (JAK1)
05203 Viral carcinogenesis
102988182 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102988182 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
102988182 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
102988182 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
102988182 (JAK1)
05161 Hepatitis B
102988182 (JAK1)
05160 Hepatitis C
102988182 (JAK1)
05171 Coronavirus disease - COVID-19
102988182 (JAK1)
05164 Influenza A
102988182 (JAK1)
05162 Measles
102988182 (JAK1)
05168 Herpes simplex virus 1 infection
102988182 (JAK1)
05163 Human cytomegalovirus infection
102988182 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
102988182 (JAK1)
05169 Epstein-Barr virus infection
102988182 (JAK1)
05165 Human papillomavirus infection
102988182 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
102988182 (JAK1)
05140 Leishmaniasis
102988182 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102988182 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcad01001
]
102988182 (JAK1)
Enzymes [BR:
pcad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
102988182 (JAK1)
Protein kinases [BR:
pcad01001
]
Non-receptor tyrosine kinases
JAK family [OT]
102988182 (JAK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
FERM_F1
Motif
Other DBs
NCBI-GeneID:
102988182
NCBI-ProteinID:
XP_023975359
UniProt:
A0A2Y9SI10
LinkDB
All DBs
Position
4
AA seq
1153 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSSKKTDVNLEAPEPGVEVLFYLSDREPLRLGGGEYTAEEL
CIRAAQECCISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNSYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
LFHPNDNGNILCYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIR
EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
CFEKSELLGVQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMGHLKKQILRTDNISFVLK
RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIMQGEHLGRGTRTHIYSGT
LTDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV
ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL
LAREGTDSECGPFIKLSDPGIPVTVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT
TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI
MRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT
GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS
GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD
FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD
SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPRNCPEEVYQLMRKCWEFQPSNRTT
FQNLIEGFEALLK
NT seq
3462 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg
agctccaagaagactgacgtgaatctggaggcccctgagccaggggtggaagtgctcttc
tatctgtcggatagggagcccctccggttgggcggcggagagtacacagcggaggagctg
tgcatcagggcggcacaggaatgctgtatatctcctctgtgtcacaacctctttgccctg
tatgatgagaacaccaagctctggtatgctccgaatcgcaccatcaccgtcgatgacaag
atgtcactccggctccactaccggatgaggttctatttcaccaactggcatgggaccaat
gataacgagcagtcagtatggcgacattctccaaagaagcagaagaacagctacgagaaa
aaaaaagtaccagatgcaacccctctccttgacgccagctcattggagtatctgtttgct
cagggacagtatgatttggtcaaatgcctggctcccattcgagaccccaagacagagcag
gatgggcatgatattgagaacgagtgtctgggaatggccgtcctggccatctcccactat
gctatgatgaagaagatgcagttgccagaacttcccaaggacatcagctacaagcgatat
attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata
aataatgttttcaaggatttcctaaaggagtttaacaacaagaccatttgtgacagcagt
gtgtccacacacgacctgaaggtgaaatacctggctaccttggaaactttgacaaaacat
tatggtgctgaaatatttgagacttccatgctactgatttcatcagaaaatgagatgaat
ctgttccatccgaatgataatggaaacattctctgctatgaagtgatggtgactggaaat
cttggaatccagtggaggcagaaaccaaatgttgttcctgttgaaaaggaaaaaaataaa
ctgaaacggaaaaaactggaaaataaacacaagaaggatgaggagaaaaacaaaatccgg
gaagagtggaacaatttttcttacttccctgagatcacgcacattgtaatcaaggagtct
gtggtcagcattaataagcaggacaacaaaaaaatggaactgaagctctcttcccacgaa
gaggccttgtcctttgtgtccctcgtggatggctacttccggctcacagcagatgcccat
cattacctctgcaccgacgtggctcccccgttgatcgtccacaacatacagaatggctgt
catggtccaatctgcacagagtatgccatcaataagttgcggcaagaaggaagcgaggag
ggaatgtatgtgctgcggtggagctgcaccgacttcgacaacatcctcatgaccgtcact
tgctttgaaaaatctgagttgctgggtgtccagaagcagttcaagaactttcagattgag
gtgcagaagggccgctacagcctgcatggctcggaccgaagcttccccagccttggagac
ctcatgggccacctgaagaagcagatcctgcgcacggacaacatcagctttgtgctgaag
cgctgctgccagcccaagccccgagaaatctccaatctgctggtggccacaaagaaagcc
caggagtggcagcctgtctaccccatgagccagctgagttttgatcggatcctcaagaaa
gatattatgcagggcgagcaccttgggagaggcacgcggacacacatctactctgggacc
ctcacggattacaaggatgacgaaggaacttccgaagagaagagaataaaagtgatcctc
aaagtcttagaccccagccacagggacatttctctggccttctttgaggcagccagcatg
atgagacaggtctcccataaacacatcgtgtacctctatggtgtttgtgtccgggatgtg
gagaatatcatggtggaagagtttgtggagggggggcccctggatctcttcatgcaccgg
aaaagtgatgtcctcaccacaccctggaagttcaaagttgccaaacagctggccagtgcc
ctgagttacttggaggataaagatctggtccacggaaacgtgtgcactaaaaacctcctc
ctggcccgcgagggcactgacagcgagtgcggccccttcatcaagctcagtgaccccggc
atccccgtcactgtgctgtccaggcaagagtgcatagaacgaatcccatggatcgctcct
gagtgtgttgaagactccaagaacctgagtgtggccgctgacaagtggagctttgggacc
acgctctgggagatctgctacaatggcgagatccccttgaaagacaagacactgattgag
aaagagagattctatgaaagccggtgcaggccagtgaccccgtcttgtaaggagctagct
gaccttatgacccgctgcatgaactacgaccccaaccagagacccttcttccgagccatc
atgagagacatcaataagctggaggagcagaatccagacatcgtatcagaaaaaaagcca
gcaactgaagtggatcccacacattttgaaaagcggttcttaaagaggatacgtgacttg
ggagagggccactttgggaaggtcgagctctgcaggtatgaccctgagggggacaataca
ggggagcaggtggccgtcaaatccctgaagcctgagagcggagggaaccacatagctgat
ctgaagaaggaaattgaaatcttaagaaacctttatcatgagaacattgtgaagtataaa
ggcatctgcacagaagacggaggaaatggtattaagctcatcatggaatttctgccttcg
ggaagtcttaaggagtatcttccaaagaataagaacaaaattaacctcaaacagcagtta
aaatatgccgttcagatttgtaaggggatggactatttgggttctcggcagtacgttcac
cgtgacttagcagcaagaaatgtccttgttgagagtgaacaccaagtgaaaattggggac
tttggtctaaccaaagccattgaaactgataaggagtactacacagtcaaggacgatcgg
gacagccctgtgttttggtatgctccagaatgtttaattcagtgtaagttttatatcgcc
tctgatgtctggtcttttggagtaactctgcatgagctgcttacttactgtgattcagat
tccagtcccatggcgttgttcctgaaaatgataggcccaactcatggccagatgacagta
acaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacgtaactgtcca
gaagaggtttatcaacttatgagaaaatgctgggaattccaaccatccaatcggacaacc
tttcagaaccttattgagggatttgaagcgcttctaaaataa
DBGET
integrated database retrieval system
