Porphyromonas cangingivalis: NCTC12856_00350
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Entry
NCTC12856_00350 CDS
T06514
Symbol
thrA
Name
(GenBank) Aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
pcag
Porphyromonas cangingivalis
Pathway
pcag00260
Glycine, serine and threonine metabolism
pcag00261
Monobactam biosynthesis
pcag00270
Cysteine and methionine metabolism
pcag00300
Lysine biosynthesis
pcag01100
Metabolic pathways
pcag01110
Biosynthesis of secondary metabolites
pcag01120
Microbial metabolism in diverse environments
pcag01230
Biosynthesis of amino acids
Brite
KEGG Orthology (KO) [BR:
pcag00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
NCTC12856_00350 (thrA)
00270 Cysteine and methionine metabolism
NCTC12856_00350 (thrA)
00300 Lysine biosynthesis
NCTC12856_00350 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
NCTC12856_00350 (thrA)
Enzymes [BR:
pcag01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
NCTC12856_00350 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
NCTC12856_00350 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
AA_kinase
Homoserine_dh
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
VEJ02355
LinkDB
All DBs
Position
1:complement(409718..412150)
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AA seq
810 aa
AA seq
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MKILKFGGKSLDNGLGIAKVVEIITDNHKKGLSPIVVVSARGNSTDTLIALIEKARRGEE
FKEDLSLFLQHQTEPSDIKFENEQTRLLNLLTGISLVGECSPKLKDEIISYGEILSARFV
AHRLEQQGYNAIAIDSGDFFLTDAQFGSASVHIETSRVKCREVFDQLSRSCIPIVTGFIA
RSKDGHRTTLGRNGSNYSAALLANFLDADMMENYTHIDGIYTANPTVVPEARKMDELSYS
DASELSQFGAEILHIKTIEPLQEKNIPLWVLNTFGYGSKQNGTLVTASPKAKSVRALASL
TQKALIHFEGRNMLGRSGIDARIFAAFKSVDVSVSLVSQGSTERGIAIVVDESDADKAVE
ALHQEFRQDISEGKTTKIYAEKGLAIVAIIGLNLSEFDRPYRALVRNRIVPLLLNNSVPD
NTLCLLVRGEEERVKALNVIHGEMFERPKRVHLAVIGHGTVGGALIDQIIHQHAQLKEQK
NIDLRIFAIANSRQLLLSRKGIGEGWQEQLQQSTHEGNMAEAIVEYGRKFALENMILVDN
TSSESIAAEYSYFASNGFDIVSSNKKSNVAPYSEYTHLRETLKKHRRSYRYETNVGAGLP
LIDNLKLLHLAGERITRIHGLFSGSLSYIFNTLSEDPSRSFRDIVEESARRGLTEPDPRE
DLSGEDVARKVLILVRELDVPAELSDVSWENPVPEELRTLSREAFEARFGELENKIEEYR
ASCSPDEVLRYVGDIVWDETNQKATLTAALRRVSKNSPLGRVSGADSCFEIYTESYGSHP
IVIQGAGAGAVVTARGVFGDLLRLAEGYEN
NT seq
2433 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatattaaaattcggtggcaaatctcttgacaacggccttggcatagccaaagtt
gtggagatcatcacagacaaccataagaaaggactctctcccatcgtggtagtatctgcc
cgagggaatagcacggacacgcttattgcactcatagaaaaagcccgaagaggagaagaa
ttcaaagaagacttatctctttttttgcaacatcagacggagccctctgacataaagttt
gaaaacgagcaaacccggctcctgaatctactcacgggcatctcgctcgtgggtgaatgc
agccctaagctcaaagacgagatcataagctatggggagatactatcggcaaggtttgtc
gcccatagacttgaacagcaagggtacaatgccattgcgatagattccggagacttcttc
ttgacagacgcacagtttggctcagcatctgtacacatagagacttcaagggtcaaatgc
cgagaagtgtttgaccaactatcccgatcctgtatccccatcgttacgggttttatcgca
cgaagcaaggatggccaccgcaccacactcggaaggaacggcagcaactacagtgcagct
ctgcttgcaaactttctggatgcggacatgatggaaaactacacccatatagatgggata
tacactgccaatccgacggtggtgccggaagcacgcaagatggacgaactctcatactcc
gatgcttcagagctttcccaattcggcgcagagatacttcacatcaagaccatcgagcct
ttgcaagaaaaaaacatccctctgtgggtactcaatactttcggctacggctccaagcag
aacggcacccttgtcactgcaagtccgaaagccaaatctgtaagagcattggcctctctt
actcaaaaagcactgatacactttgagggacgcaatatgctcggacgctcagggatagat
gcgcggatattcgcagcattcaagagtgtggatgtaagtgtcagccttgtgtcccaaggg
tcgacagagcgtggtatagccatagtggtcgatgagtcggatgcagataaggccgtggaa
gctcttcaccaagagtttcgccaagatatttcggaaggtaagacaaccaagatctacgca
gagaaagggcttgccatagtcgccatcatcgggctcaatctgtctgagtttgaccgccca
tatagggcactcgtccgcaatcgtattgtccctctcctccttaacaactctgtgccggac
aataccctctgcctacttgtccgaggagaagaggagagagtcaaagctctcaatgtgatc
catggagagatgtttgagcgacccaagcgtgtccacctcgcagttataggtcatggcaca
gtcggaggtgctctcatagatcagattatacaccagcatgcacaactgaaagagcagaaa
aacatagacctaaggatctttgccatcgccaactcccggcagttgcttctttctcgaaaa
gggatcggggaaggctggcaagagcagctacaacaatccacacacgagggcaatatggca
gaagccatcgtagagtatggtcggaagtttgcgttggaaaacatgatcttggtcgacaat
acctcttctgaaagcatcgcagccgaatactcatactttgcgagcaacggtttcgacatc
gtctcctccaacaagaagtccaatgtagcaccctattcggagtacacacacctaagagag
acactcaagaaacacaggagaagctaccgatatgaaacaaatgtgggagccggcctacca
ctgatagacaatctcaaactgctccacttggcaggcgagcgcatcacacgtattcacgga
cttttctcagggagtctgagctacatcttcaacactctttcggaagacccctcccggtct
ttccgtgacatcgtcgaagagtccgcccgaagggggctcacagagcctgaccctcgtgag
gatctcagtggagaggatgttgcccgaaaggttctgatcttggtgagagaactggatgtg
ccggctgagctctccgatgtgtcgtgggagaaccctgttccggaagagttgagaacactc
tctcgggaggcgttcgaggcacgcttcggggaactggaaaataagattgaagagtatcga
gcctcttgctcacccgacgaagtcctcagatatgtgggagacatcgtctgggacgagacc
aatcagaaggccaccctcacagcggcactcagacgagtctccaaaaattcgcctttgggc
agagtgagtggagcagacagttgtttcgagatctataccgaaagctacggaagccacccg
atcgtgatacaaggagccggagccggagcagtcgtgacggcacggggtgtatttggcgat
ctgctgagattggccgagggctacgagaactga
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