Porphyromonas cangingivalis: NCTC12856_01834
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Entry
NCTC12856_01834 CDS
T06514
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
pcag
Porphyromonas cangingivalis
Pathway
pcag00300
Lysine biosynthesis
pcag00550
Peptidoglycan biosynthesis
pcag01100
Metabolic pathways
pcag01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
pcag00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NCTC12856_01834 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NCTC12856_01834 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NCTC12856_01834 (murF)
Enzymes [BR:
pcag01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NCTC12856_01834 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
VEJ04547
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Position
1:2085737..2087032
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AA seq
431 aa
AA seq
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MTTIQHLYEIYLRHPGICTDTRKLCKGDLFFALHGANFDGNDFALRALEQGAAYAIVDKD
VAPSDPRCLLVEDTLTALQALATHHRRQFDIPVIGITGTNGKTTTKELIRSVLSRKYNLL
ATEGNLNNHIGVPLMILRLDSSHEMALIEMGAGAPGEIHTLVEIAQPNVGLITNIGRAHL
QGFGSIEGVLRTKSELPEYLYAHEGTFLLNSDDPLLVEKWGTQTVLTYGQEGNYVSGKVA
GHLPYLSVSVGETVVHSQLVGAYNLINILAAIAMGKYFEVPEADIYAGIEGYQPTNNRSQ
LVRLEGGSQLIVDAYNANPSSMAVAIDNLVDSPARHKVAILGDMLELGEATEEEHRRVLT
HLSAHPEVKALLCGPCFRKVAGEAFLAFEKVEDICEYLRRHPLPSESLVLIKGSRGIALE
KVLPLFCSGSL
NT seq
1296 nt
NT seq
+upstream
nt +downstream
nt
atgaccaccatacaacacctctacgagatctatctgcgccatcccggtatatgtacggac
accagaaagttgtgtaagggggatttattcttcgctcttcatggagccaattttgatggc
aacgactttgccctccgtgctcttgaacaaggggcggcctatgccatcgttgataaggac
gtggcaccctccgatcctcgttgccttcttgtcgaagatacgttgacggcacttcaagcc
cttgccacccatcaccgccgacagtttgacatccctgtcatcggcatcacgggcaccaac
ggtaagacgacgacgaaggagctcatccgctccgtcctctctcgcaagtacaacctcctt
gccaccgagggcaacctcaacaaccatatcggtgtaccgctcatgatcctcagactcgac
tcctcccacgagatggctctcatcgagatgggtgcaggggcacccggagagatccatacc
ttggtagagatcgcacagccgaatgtggggctgattacaaacatcggtagggctcactta
caaggatttgggtcgatagaaggagtcttgcgtaccaagagtgagcttcccgagtatctc
tatgctcatgagggtactttcctcctgaatagtgacgatccactcttggttgaaaaatgg
ggaacacagaccgtacttacctatgggcaagagggcaactatgtctcaggcaaagtggca
ggtcatctgccctacctgtcggtctcggtcggagaaacagtggtccactctcaactcgta
ggggcatacaatctcatcaatatccttgctgcaatcgcgatgggcaaatactttgaagtg
cccgaagccgacatctatgcaggtatcgaggggtatcaacccaccaataaccgttcgcag
ctcgtccgacttgagggtggctcccaactcatcgtcgatgcctataatgccaacccctca
agtatggctgttgccattgacaatctcgttgactcgccggctcgacacaaagtcgccatc
ctcggagacatgctcgaactcggagaagccaccgaagaggagcatcgtagggtcttgaca
cacctctctgctcatcccgaagtcaaggctctactctgtggcccatgcttccgaaaagtt
gcaggcgaggcatttcttgcctttgagaaggtcgaggacatctgtgaatatctccgccgg
catcctctcccatccgaaagccttgtgctcatcaaaggctcacgtgggatagccctcgaa
aaggttctgcctcttttctgttcaggcagtctatga
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