Phascolarctos cinereus (koala): 110194600
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Entry
110194600 CDS
T05867
Gene name
PTK2
Definition
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw01522
Endocrine resistance
pcw04012
ErbB signaling pathway
pcw04062
Chemokine signaling pathway
pcw04151
PI3K-Akt signaling pathway
pcw04360
Axon guidance
pcw04370
VEGF signaling pathway
pcw04510
Focal adhesion
pcw04670
Leukocyte transendothelial migration
pcw04810
Regulation of actin cytoskeleton
pcw04935
Growth hormone synthesis, secretion and action
pcw05100
Bacterial invasion of epithelial cells
pcw05135
Yersinia infection
pcw05146
Amoebiasis
pcw05163
Human cytomegalovirus infection
pcw05165
Human papillomavirus infection
pcw05170
Human immunodeficiency virus 1 infection
pcw05200
Pathways in cancer
pcw05202
Transcriptional misregulation in cancer
pcw05205
Proteoglycans in cancer
pcw05222
Small cell lung cancer
pcw05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
110194600 (PTK2)
04370 VEGF signaling pathway
110194600 (PTK2)
04151 PI3K-Akt signaling pathway
110194600 (PTK2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
110194600 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
110194600 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
110194600 (PTK2)
04062 Chemokine signaling pathway
110194600 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
110194600 (PTK2)
09158 Development and regeneration
04360 Axon guidance
110194600 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110194600 (PTK2)
05202 Transcriptional misregulation in cancer
110194600 (PTK2)
05205 Proteoglycans in cancer
110194600 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
110194600 (PTK2)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
110194600 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
110194600 (PTK2)
05100 Bacterial invasion of epithelial cells
110194600 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
110194600 (PTK2)
05163 Human cytomegalovirus infection
110194600 (PTK2)
05165 Human papillomavirus infection
110194600 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
110194600 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
110194600 (PTK2)
Enzymes [BR:
pcw01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
110194600 (PTK2)
Protein kinases [BR:
pcw01001
]
Non-receptor tyrosine kinases
FAK family
110194600 (PTK2)
Protein phosphatases and associated proteins [BR:
pcw01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
110194600 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_N_2
FERM_M
Kinase-like
FERM_F2
Motif
Other DBs
NCBI-GeneID:
110194600
NCBI-ProteinID:
XP_020822686
UniProt:
A0A6P5IUR9
LinkDB
All DBs
Position
Unknown
AA seq
1112 aa
AA seq
DB search
MLLELAGQPALKPAGAIYMEKSGCSPFPICWAKEYDRYLASSKTMAAAYLDPNLNHAPSS
STKTHLSTGMERSPGAMERVLKVFHYFENSNEPTTWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHLDMGVSNVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKNDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPKSLLESVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGSNPTHLADFNQVQTIQYSNSDDKDRKGML
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKL
ANNEKQGVRTHTVSVSDEISGDETDDYAEIIDEEDTYTMPSKSYGIDEARDYEIQRERIE
LGRCIGEGQFGDVHQGVYMSPENPAMAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHI
VKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFV
HRDIAARNVLVSSADCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSAS
DVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDP
SRRPRFTELKAQLSTILEEEKLQQEERMRMESRRQVTVSWDSGGSDEAPPKPSRPGYPSP
RSSEGFYPSPQHMVQANHYQVSGYPGSHGITAMAGSIYPGQASLLDQTESWNHRPQEVSM
WQPNMEDSATLDMRGLGQVLPAHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGS
IDREDGSLQGPTGNQHIYQPVGKPDHAAPPKKPPRPGAPSHLGSLASLNSPVDSYNEGVK
PWRLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLA
LRTLLATVDETIPMLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQM
LTAAHALAVDAKNLLDVIDQARLKMLGQARPH
NT seq
3339 nt
NT seq
+upstream
nt +downstream
nt
atgttgttggaactggctggccaaccggccctgaaaccagcaggtgctatctatatggag
aaaagcggctgtagcccatttccaatatgctgggctaaagaatatgacagatacctagca
tctagcaaaaccatggcagctgcttaccttgacccaaacttgaatcacgccccaagttca
agtacaaagacacacctcagtactgggatggagcgttctcctggggcaatggagcgagta
ttaaaagtctttcattattttgaaaatagtaatgagccaaccacatgggccagtattatt
aggcatggagatgccactgatgtcaggggcatcattcagaagatagtggacagtcacaaa
gtaaagcatgtggcctgttatggatttcgactcagtcatcttcgttcagaggaagttcac
tggctgcatttggatatgggtgtttccaatgtgagagaaaaatatgaactagcccaccca
ccggaggagtggaaatatgagttgagaattcgttatttgccaaaaggatttctgaaccag
tttacagaagacaagccaactttgaatttcttttatcagcaggtgaaaaacgactatatg
ttagaaatagctgatcaagtggaccaggaaattgctttgaagttgggttgccttgaaata
cggagatcatactgggagatgaggggcaatgccctggagaagaaatctaactatgaagta
ttagaaaaggatgttggtttaaagagattttttcctaagagtttgctggaatctgtcaag
gccaaaaccctcagaaaactgatacagcaaacatttcgtcaatttgccaacctaaataga
gaagaaagtattctgaaattctttgagattctctctcctgtgtacagatttgataaagaa
tgcttcaaatgtgctcttgggtcaagttggatcatttccgtggagctggcaattggccca
gaagaaggcatcagttaccttacagacaagggctccaatcctacacatctcgcagacttc
aatcaagttcagaccattcagtattcaaacagtgatgacaaagacagaaaaggaatgctg
caactcaaaatagcaggagcacctgagcctctcacagtgacagccccatctttaaccatt
gcagagaatatggctgacttaatcgatggatattgccgactagttaatggagccacacag
tcttttatcattagaccccagaaagaaggtgaacgagccttaccatccataccaaagcta
gccaacaatgagaagcaaggagtaaggacacatacagtctctgtgtcagatgaaattagt
ggggacgaaacagatgactacgctgagattatagatgaagaagatacttatacaatgccc
tcaaaaagctatggaatagatgaagccagggattatgagatacaaagggaaaggatagaa
cttggacgctgtattggagaaggccagtttggagatgtacatcaaggagtttacatgagt
ccagagaatccagcaatggcagttgcaattaaaacatgtaaaaattgtacctcagacagt
gtgagagaaaaattccttcaagaagccttaacaatgcgtcagtttgaccacccacatatt
gtgaaattgattggagtcataacagaaaatccagtctggataatcatggagctctgcaca
ctaggggagctgagatcatttttgcaagtgagaaaatacagcttggatttggcatctttg
attctatatgcttaccagcttagtacagcccttgcctacctagaaagtaaaagatttgtg
catagggacattgctgctagaaatgtgctggtatcttcagctgactgtgtaaaattagga
gactttggtttgtctcgatatatggaagatagtacttactacaaagcttccaaaggaaaa
ttacctattaaatggatggctccagagtcaatcaactttagacgttttacctcagctagt
gatgtatggatgtttggtgtgtgcatgtgggaaattttgatgcatggtgtaaagcctttc
caaggagtgaagaacaatgacgtaattggtcgaattgaaaatggtgaacggttaccaatg
cctccaaattgtcctcctaccctttacagccttatgactaaatgctgggcatatgatccc
agcagacgacccaggtttactgaactcaaagcacagctcagtacaatactggaggaggag
aagcttcagcaagaagaacgaatgagaatggaatccagaaggcaggtcacagtgtcctgg
gattcaggaggctcagacgaagctcctcccaagcccagccgacctggttatcctagccca
agatccagtgaaggcttttatcctagtccacaacatatggtacaagccaatcattatcag
gtctctggctatcctggttctcatggaataacagccatggctggcagcatttatcctggt
caggcatctctgttggaccaaacagagtcttggaaccaccgacctcaagaggtgtcaatg
tggcagcccaacatggaggattctgccacattggacatgaggggattaggccaggtcctt
ccagcacatcttatggaagagaggttgatacgacagcagcaggaaatggaagaagatcag
cgttggcttgagaaggaggagagatttttgaaacctgatgtgaggctctctcgaggcagt
attgaccgagaggatggaagtcttcagggtccgactggtaaccagcacatatatcaacct
gtgggtaagccagatcatgcagctccaccaaagaaaccacctcgcccaggagcacccagc
catctgggaagccttgccagcctcaacagccctgtggatagttataatgaaggagtaaag
ccatggaggctgcagccccaggaaatcagccccccacctactgccaatctggaccgctct
aatgacaaggtctatgaaaatgtaaccggcttggtgaaagctgtcatagaaatgtccagc
aagatccagcctgcccccccagaggaatatgttcctatggtaaaggaagttggcttggcc
ctaagaacattgctagcaacagtggatgagaccattcctatgcttccagcaagcactcac
agagagattgagatggcccaaaagctgttgaattcggacttgggtgagctgatcaacaag
atgaaattggcacaacaatacgtcatgaccagccttcagcaggaatacaaaaagcaaatg
ctaactgccgctcatgcactggctgtagatgccaaaaacttactagatgtcattgaccaa
gcaagattgaaaatgctggggcaggccaggccacactga
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integrated database retrieval system
