Phascolarctos cinereus (koala): 110202713
Help
Entry
110202713 CDS
T05867
Gene name
AKT2
Definition
(RefSeq) RAC-beta serine/threonine-protein kinase
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw01521
EGFR tyrosine kinase inhibitor resistance
pcw01522
Endocrine resistance
pcw01524
Platinum drug resistance
pcw04010
MAPK signaling pathway
pcw04012
ErbB signaling pathway
pcw04014
Ras signaling pathway
pcw04015
Rap1 signaling pathway
pcw04022
cGMP-PKG signaling pathway
pcw04024
cAMP signaling pathway
pcw04062
Chemokine signaling pathway
pcw04066
HIF-1 signaling pathway
pcw04068
FoxO signaling pathway
pcw04071
Sphingolipid signaling pathway
pcw04072
Phospholipase D signaling pathway
pcw04140
Autophagy - animal
pcw04150
mTOR signaling pathway
pcw04151
PI3K-Akt signaling pathway
pcw04152
AMPK signaling pathway
pcw04210
Apoptosis
pcw04211
Longevity regulating pathway
pcw04213
Longevity regulating pathway - multiple species
pcw04218
Cellular senescence
pcw04261
Adrenergic signaling in cardiomyocytes
pcw04370
VEGF signaling pathway
pcw04371
Apelin signaling pathway
pcw04380
Osteoclast differentiation
pcw04510
Focal adhesion
pcw04550
Signaling pathways regulating pluripotency of stem cells
pcw04611
Platelet activation
pcw04613
Neutrophil extracellular trap formation
pcw04620
Toll-like receptor signaling pathway
pcw04625
C-type lectin receptor signaling pathway
pcw04630
JAK-STAT signaling pathway
pcw04660
T cell receptor signaling pathway
pcw04662
B cell receptor signaling pathway
pcw04664
Fc epsilon RI signaling pathway
pcw04666
Fc gamma R-mediated phagocytosis
pcw04668
TNF signaling pathway
pcw04722
Neurotrophin signaling pathway
pcw04725
Cholinergic synapse
pcw04728
Dopaminergic synapse
pcw04910
Insulin signaling pathway
pcw04914
Progesterone-mediated oocyte maturation
pcw04915
Estrogen signaling pathway
pcw04917
Prolactin signaling pathway
pcw04919
Thyroid hormone signaling pathway
pcw04920
Adipocytokine signaling pathway
pcw04922
Glucagon signaling pathway
pcw04923
Regulation of lipolysis in adipocytes
pcw04926
Relaxin signaling pathway
pcw04929
GnRH secretion
pcw04931
Insulin resistance
pcw04932
Non-alcoholic fatty liver disease
pcw04933
AGE-RAGE signaling pathway in diabetic complications
pcw04935
Growth hormone synthesis, secretion and action
pcw04973
Carbohydrate digestion and absorption
pcw05010
Alzheimer disease
pcw05017
Spinocerebellar ataxia
pcw05132
Salmonella infection
pcw05135
Yersinia infection
pcw05142
Chagas disease
pcw05145
Toxoplasmosis
pcw05152
Tuberculosis
pcw05160
Hepatitis C
pcw05161
Hepatitis B
pcw05162
Measles
pcw05163
Human cytomegalovirus infection
pcw05164
Influenza A
pcw05165
Human papillomavirus infection
pcw05166
Human T-cell leukemia virus 1 infection
pcw05167
Kaposi sarcoma-associated herpesvirus infection
pcw05168
Herpes simplex virus 1 infection
pcw05169
Epstein-Barr virus infection
pcw05170
Human immunodeficiency virus 1 infection
pcw05200
Pathways in cancer
pcw05205
Proteoglycans in cancer
pcw05210
Colorectal cancer
pcw05211
Renal cell carcinoma
pcw05212
Pancreatic cancer
pcw05213
Endometrial cancer
pcw05214
Glioma
pcw05215
Prostate cancer
pcw05218
Melanoma
pcw05220
Chronic myeloid leukemia
pcw05221
Acute myeloid leukemia
pcw05222
Small cell lung cancer
pcw05223
Non-small cell lung cancer
pcw05224
Breast cancer
pcw05225
Hepatocellular carcinoma
pcw05226
Gastric cancer
pcw05230
Central carbon metabolism in cancer
pcw05231
Choline metabolism in cancer
pcw05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
pcw05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110202713 (AKT2)
04012 ErbB signaling pathway
110202713 (AKT2)
04014 Ras signaling pathway
110202713 (AKT2)
04015 Rap1 signaling pathway
110202713 (AKT2)
04370 VEGF signaling pathway
110202713 (AKT2)
04371 Apelin signaling pathway
110202713 (AKT2)
04630 JAK-STAT signaling pathway
110202713 (AKT2)
04668 TNF signaling pathway
110202713 (AKT2)
04066 HIF-1 signaling pathway
110202713 (AKT2)
04068 FoxO signaling pathway
110202713 (AKT2)
04072 Phospholipase D signaling pathway
110202713 (AKT2)
04071 Sphingolipid signaling pathway
110202713 (AKT2)
04024 cAMP signaling pathway
110202713 (AKT2)
04022 cGMP-PKG signaling pathway
110202713 (AKT2)
04151 PI3K-Akt signaling pathway
110202713 (AKT2)
04152 AMPK signaling pathway
110202713 (AKT2)
04150 mTOR signaling pathway
110202713 (AKT2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
110202713 (AKT2)
09143 Cell growth and death
04210 Apoptosis
110202713 (AKT2)
04218 Cellular senescence
110202713 (AKT2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
110202713 (AKT2)
04550 Signaling pathways regulating pluripotency of stem cells
110202713 (AKT2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
110202713 (AKT2)
04613 Neutrophil extracellular trap formation
110202713 (AKT2)
04620 Toll-like receptor signaling pathway
110202713 (AKT2)
04625 C-type lectin receptor signaling pathway
110202713 (AKT2)
04660 T cell receptor signaling pathway
110202713 (AKT2)
04662 B cell receptor signaling pathway
110202713 (AKT2)
04664 Fc epsilon RI signaling pathway
110202713 (AKT2)
04666 Fc gamma R-mediated phagocytosis
110202713 (AKT2)
04062 Chemokine signaling pathway
110202713 (AKT2)
09152 Endocrine system
04910 Insulin signaling pathway
110202713 (AKT2)
04922 Glucagon signaling pathway
110202713 (AKT2)
04923 Regulation of lipolysis in adipocytes
110202713 (AKT2)
04920 Adipocytokine signaling pathway
110202713 (AKT2)
04929 GnRH secretion
110202713 (AKT2)
04915 Estrogen signaling pathway
110202713 (AKT2)
04914 Progesterone-mediated oocyte maturation
110202713 (AKT2)
04917 Prolactin signaling pathway
110202713 (AKT2)
04926 Relaxin signaling pathway
110202713 (AKT2)
04935 Growth hormone synthesis, secretion and action
110202713 (AKT2)
04919 Thyroid hormone signaling pathway
110202713 (AKT2)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
110202713 (AKT2)
09154 Digestive system
04973 Carbohydrate digestion and absorption
110202713 (AKT2)
09156 Nervous system
04725 Cholinergic synapse
110202713 (AKT2)
04728 Dopaminergic synapse
110202713 (AKT2)
04722 Neurotrophin signaling pathway
110202713 (AKT2)
09158 Development and regeneration
04380 Osteoclast differentiation
110202713 (AKT2)
09149 Aging
04211 Longevity regulating pathway
110202713 (AKT2)
04213 Longevity regulating pathway - multiple species
110202713 (AKT2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110202713 (AKT2)
05205 Proteoglycans in cancer
110202713 (AKT2)
05230 Central carbon metabolism in cancer
110202713 (AKT2)
05231 Choline metabolism in cancer
110202713 (AKT2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
110202713 (AKT2)
09162 Cancer: specific types
05210 Colorectal cancer
110202713 (AKT2)
05212 Pancreatic cancer
110202713 (AKT2)
05225 Hepatocellular carcinoma
110202713 (AKT2)
05226 Gastric cancer
110202713 (AKT2)
05214 Glioma
110202713 (AKT2)
05221 Acute myeloid leukemia
110202713 (AKT2)
05220 Chronic myeloid leukemia
110202713 (AKT2)
05218 Melanoma
110202713 (AKT2)
05211 Renal cell carcinoma
110202713 (AKT2)
05215 Prostate cancer
110202713 (AKT2)
05213 Endometrial cancer
110202713 (AKT2)
05224 Breast cancer
110202713 (AKT2)
05222 Small cell lung cancer
110202713 (AKT2)
05223 Non-small cell lung cancer
110202713 (AKT2)
09164 Neurodegenerative disease
05010 Alzheimer disease
110202713 (AKT2)
05017 Spinocerebellar ataxia
110202713 (AKT2)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
110202713 (AKT2)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
110202713 (AKT2)
04931 Insulin resistance
110202713 (AKT2)
04933 AGE-RAGE signaling pathway in diabetic complications
110202713 (AKT2)
09171 Infectious disease: bacterial
05132 Salmonella infection
110202713 (AKT2)
05135 Yersinia infection
110202713 (AKT2)
05152 Tuberculosis
110202713 (AKT2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
110202713 (AKT2)
05170 Human immunodeficiency virus 1 infection
110202713 (AKT2)
05161 Hepatitis B
110202713 (AKT2)
05160 Hepatitis C
110202713 (AKT2)
05164 Influenza A
110202713 (AKT2)
05162 Measles
110202713 (AKT2)
05168 Herpes simplex virus 1 infection
110202713 (AKT2)
05163 Human cytomegalovirus infection
110202713 (AKT2)
05167 Kaposi sarcoma-associated herpesvirus infection
110202713 (AKT2)
05169 Epstein-Barr virus infection
110202713 (AKT2)
05165 Human papillomavirus infection
110202713 (AKT2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
110202713 (AKT2)
05142 Chagas disease
110202713 (AKT2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110202713 (AKT2)
01524 Platinum drug resistance
110202713 (AKT2)
01522 Endocrine resistance
110202713 (AKT2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcw01001
]
110202713 (AKT2)
Enzymes [BR:
pcw01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
110202713 (AKT2)
Protein kinases [BR:
pcw01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
110202713 (AKT2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Kinase-like
Pkinase_C
PH_11
Motif
Other DBs
NCBI-GeneID:
110202713
NCBI-ProteinID:
XP_020834643
UniProt:
A0A6P5JMP9
LinkDB
All DBs
Position
Unknown
AA seq
481 aa
AA seq
DB search
MNEVSVVKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEVPDQSLPPLNNFSVAEC
QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKNQEPVEDAM
DYKCGSPSDSSVAEEMEVAVSKTRTKATMNDFDYLKLLGKGTFGKVILVREKATGRYYAM
KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTNDRLCFVMEYANGGELFFH
LSRERVFTEDRARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG
ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMTCGRLPFYNQDHERLFE
LILLEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPRDAKEVMEHRFFSAINWQDVLQK
KLPPPFKPQVTSEIDTRYFDDEFTAQSITITPPDRYDSMGSLEPDQRTHFPQFSYSASIR
E
NT seq
1446 nt
NT seq
+upstream
nt +downstream
nt
atgaacgaggtgtccgtcgtcaaagaaggctggctccacaagagaggtgaatacatcaag
acctggagacctcgttacttcctgttaaaaagcgatggttcattcatcggctacaaagag
aggccagaggtccctgaccagagtttgccccctttaaataacttttctgtagcagaatgc
cagctaatgaaaacagagcgacctcggcccaacacctttgtcatccgatgcttgcaatgg
acaacggttatcgaaaggacctttcacgtggattctccagatgagagggaggagtggatg
agggccatccagatggtggccaacagcctgaagaatcaggagcccgtggaagacgcgatg
gactacaaatgtggctcccccagtgactcctcagtggccgaggagatggaagtggctgtc
agcaaaacacggacgaaggcgaccatgaatgactttgactatctcaagcttctgggcaaa
ggcacctttggcaaagtcatcctggtgcgggagaaggccacagggcgctactacgccatg
aagatcctgaggaaggaggtcatcatcgccaaggatgaagttgcccacacagtcactgag
agtcgagtcctacagaataccaggcacccgtttctcacagcactgaagtatgcctttcag
acaaatgaccgcctctgttttgtgatggagtatgccaacggtggggagctgtttttccac
ctgtcgagagagcgcgtcttcacggaggacagggcgcggttctacggggccgagatcgtc
tctgccttggagtacctgcactcccgggatgtggtctacagggacatcaagctggagaac
ctcatgctggacaaagacggacacatcaagatcactgactttggcctctgcaaggagggc
atcagtgacggggccaccatgaagaccttctgcggcaccccggagtacctagccccagag
gtgctggaggacaacgactacgggcgggcggtggactggtgggggctgggcgtggtgatg
tacgagatgacatgtggccggctgcccttctacaaccaggaccacgagcgcctcttcgag
ctgattctcctggaggagatccgttttccgcgcacgctcagccccgaggccaagtctctg
ctggctgggctgctgaagaaggaccccaagcagaggctgggcgggggaccccgggatgcc
aaggaggtcatggagcaccgcttcttctcggccatcaattggcaggatgtcttgcagaag
aagctcccacctccatttaagccccaggtcacatcagagattgacacacggtacttcgat
gatgaattcacagcgcagtccatcaccatcacccccccagaccgatatgacagcatgggc
tcccttgaacctgaccagcgcacccacttcccacagttctcttactcagccagcatccgg
gagtga
Phascolarctos cinereus (koala): 110203042
Help
Entry
110203042 CDS
T05867
Gene name
AKT1
Definition
(RefSeq) LOW QUALITY PROTEIN: RAC-alpha serine/threonine-protein kinase
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw01521
EGFR tyrosine kinase inhibitor resistance
pcw01522
Endocrine resistance
pcw01524
Platinum drug resistance
pcw04010
MAPK signaling pathway
pcw04012
ErbB signaling pathway
pcw04014
Ras signaling pathway
pcw04015
Rap1 signaling pathway
pcw04022
cGMP-PKG signaling pathway
pcw04024
cAMP signaling pathway
pcw04062
Chemokine signaling pathway
pcw04066
HIF-1 signaling pathway
pcw04068
FoxO signaling pathway
pcw04071
Sphingolipid signaling pathway
pcw04072
Phospholipase D signaling pathway
pcw04140
Autophagy - animal
pcw04150
mTOR signaling pathway
pcw04151
PI3K-Akt signaling pathway
pcw04152
AMPK signaling pathway
pcw04210
Apoptosis
pcw04211
Longevity regulating pathway
pcw04213
Longevity regulating pathway - multiple species
pcw04218
Cellular senescence
pcw04261
Adrenergic signaling in cardiomyocytes
pcw04370
VEGF signaling pathway
pcw04371
Apelin signaling pathway
pcw04380
Osteoclast differentiation
pcw04510
Focal adhesion
pcw04550
Signaling pathways regulating pluripotency of stem cells
pcw04611
Platelet activation
pcw04613
Neutrophil extracellular trap formation
pcw04620
Toll-like receptor signaling pathway
pcw04625
C-type lectin receptor signaling pathway
pcw04630
JAK-STAT signaling pathway
pcw04660
T cell receptor signaling pathway
pcw04662
B cell receptor signaling pathway
pcw04664
Fc epsilon RI signaling pathway
pcw04666
Fc gamma R-mediated phagocytosis
pcw04668
TNF signaling pathway
pcw04722
Neurotrophin signaling pathway
pcw04725
Cholinergic synapse
pcw04728
Dopaminergic synapse
pcw04910
Insulin signaling pathway
pcw04914
Progesterone-mediated oocyte maturation
pcw04915
Estrogen signaling pathway
pcw04917
Prolactin signaling pathway
pcw04919
Thyroid hormone signaling pathway
pcw04920
Adipocytokine signaling pathway
pcw04922
Glucagon signaling pathway
pcw04923
Regulation of lipolysis in adipocytes
pcw04926
Relaxin signaling pathway
pcw04929
GnRH secretion
pcw04931
Insulin resistance
pcw04932
Non-alcoholic fatty liver disease
pcw04933
AGE-RAGE signaling pathway in diabetic complications
pcw04935
Growth hormone synthesis, secretion and action
pcw04973
Carbohydrate digestion and absorption
pcw05010
Alzheimer disease
pcw05017
Spinocerebellar ataxia
pcw05132
Salmonella infection
pcw05135
Yersinia infection
pcw05142
Chagas disease
pcw05145
Toxoplasmosis
pcw05152
Tuberculosis
pcw05160
Hepatitis C
pcw05161
Hepatitis B
pcw05162
Measles
pcw05163
Human cytomegalovirus infection
pcw05164
Influenza A
pcw05165
Human papillomavirus infection
pcw05166
Human T-cell leukemia virus 1 infection
pcw05167
Kaposi sarcoma-associated herpesvirus infection
pcw05168
Herpes simplex virus 1 infection
pcw05169
Epstein-Barr virus infection
pcw05170
Human immunodeficiency virus 1 infection
pcw05200
Pathways in cancer
pcw05205
Proteoglycans in cancer
pcw05210
Colorectal cancer
pcw05211
Renal cell carcinoma
pcw05212
Pancreatic cancer
pcw05213
Endometrial cancer
pcw05214
Glioma
pcw05215
Prostate cancer
pcw05218
Melanoma
pcw05220
Chronic myeloid leukemia
pcw05221
Acute myeloid leukemia
pcw05222
Small cell lung cancer
pcw05223
Non-small cell lung cancer
pcw05224
Breast cancer
pcw05225
Hepatocellular carcinoma
pcw05226
Gastric cancer
pcw05230
Central carbon metabolism in cancer
pcw05231
Choline metabolism in cancer
pcw05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
pcw05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110203042 (AKT1)
04012 ErbB signaling pathway
110203042 (AKT1)
04014 Ras signaling pathway
110203042 (AKT1)
04015 Rap1 signaling pathway
110203042 (AKT1)
04370 VEGF signaling pathway
110203042 (AKT1)
04371 Apelin signaling pathway
110203042 (AKT1)
04630 JAK-STAT signaling pathway
110203042 (AKT1)
04668 TNF signaling pathway
110203042 (AKT1)
04066 HIF-1 signaling pathway
110203042 (AKT1)
04068 FoxO signaling pathway
110203042 (AKT1)
04072 Phospholipase D signaling pathway
110203042 (AKT1)
04071 Sphingolipid signaling pathway
110203042 (AKT1)
04024 cAMP signaling pathway
110203042 (AKT1)
04022 cGMP-PKG signaling pathway
110203042 (AKT1)
04151 PI3K-Akt signaling pathway
110203042 (AKT1)
04152 AMPK signaling pathway
110203042 (AKT1)
04150 mTOR signaling pathway
110203042 (AKT1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
110203042 (AKT1)
09143 Cell growth and death
04210 Apoptosis
110203042 (AKT1)
04218 Cellular senescence
110203042 (AKT1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
110203042 (AKT1)
04550 Signaling pathways regulating pluripotency of stem cells
110203042 (AKT1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
110203042 (AKT1)
04613 Neutrophil extracellular trap formation
110203042 (AKT1)
04620 Toll-like receptor signaling pathway
110203042 (AKT1)
04625 C-type lectin receptor signaling pathway
110203042 (AKT1)
04660 T cell receptor signaling pathway
110203042 (AKT1)
04662 B cell receptor signaling pathway
110203042 (AKT1)
04664 Fc epsilon RI signaling pathway
110203042 (AKT1)
04666 Fc gamma R-mediated phagocytosis
110203042 (AKT1)
04062 Chemokine signaling pathway
110203042 (AKT1)
09152 Endocrine system
04910 Insulin signaling pathway
110203042 (AKT1)
04922 Glucagon signaling pathway
110203042 (AKT1)
04923 Regulation of lipolysis in adipocytes
110203042 (AKT1)
04920 Adipocytokine signaling pathway
110203042 (AKT1)
04929 GnRH secretion
110203042 (AKT1)
04915 Estrogen signaling pathway
110203042 (AKT1)
04914 Progesterone-mediated oocyte maturation
110203042 (AKT1)
04917 Prolactin signaling pathway
110203042 (AKT1)
04926 Relaxin signaling pathway
110203042 (AKT1)
04935 Growth hormone synthesis, secretion and action
110203042 (AKT1)
04919 Thyroid hormone signaling pathway
110203042 (AKT1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
110203042 (AKT1)
09154 Digestive system
04973 Carbohydrate digestion and absorption
110203042 (AKT1)
09156 Nervous system
04725 Cholinergic synapse
110203042 (AKT1)
04728 Dopaminergic synapse
110203042 (AKT1)
04722 Neurotrophin signaling pathway
110203042 (AKT1)
09158 Development and regeneration
04380 Osteoclast differentiation
110203042 (AKT1)
09149 Aging
04211 Longevity regulating pathway
110203042 (AKT1)
04213 Longevity regulating pathway - multiple species
110203042 (AKT1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110203042 (AKT1)
05205 Proteoglycans in cancer
110203042 (AKT1)
05230 Central carbon metabolism in cancer
110203042 (AKT1)
05231 Choline metabolism in cancer
110203042 (AKT1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
110203042 (AKT1)
09162 Cancer: specific types
05210 Colorectal cancer
110203042 (AKT1)
05212 Pancreatic cancer
110203042 (AKT1)
05225 Hepatocellular carcinoma
110203042 (AKT1)
05226 Gastric cancer
110203042 (AKT1)
05214 Glioma
110203042 (AKT1)
05221 Acute myeloid leukemia
110203042 (AKT1)
05220 Chronic myeloid leukemia
110203042 (AKT1)
05218 Melanoma
110203042 (AKT1)
05211 Renal cell carcinoma
110203042 (AKT1)
05215 Prostate cancer
110203042 (AKT1)
05213 Endometrial cancer
110203042 (AKT1)
05224 Breast cancer
110203042 (AKT1)
05222 Small cell lung cancer
110203042 (AKT1)
05223 Non-small cell lung cancer
110203042 (AKT1)
09164 Neurodegenerative disease
05010 Alzheimer disease
110203042 (AKT1)
05017 Spinocerebellar ataxia
110203042 (AKT1)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
110203042 (AKT1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
110203042 (AKT1)
04931 Insulin resistance
110203042 (AKT1)
04933 AGE-RAGE signaling pathway in diabetic complications
110203042 (AKT1)
09171 Infectious disease: bacterial
05132 Salmonella infection
110203042 (AKT1)
05135 Yersinia infection
110203042 (AKT1)
05152 Tuberculosis
110203042 (AKT1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
110203042 (AKT1)
05170 Human immunodeficiency virus 1 infection
110203042 (AKT1)
05161 Hepatitis B
110203042 (AKT1)
05160 Hepatitis C
110203042 (AKT1)
05164 Influenza A
110203042 (AKT1)
05162 Measles
110203042 (AKT1)
05168 Herpes simplex virus 1 infection
110203042 (AKT1)
05163 Human cytomegalovirus infection
110203042 (AKT1)
05167 Kaposi sarcoma-associated herpesvirus infection
110203042 (AKT1)
05169 Epstein-Barr virus infection
110203042 (AKT1)
05165 Human papillomavirus infection
110203042 (AKT1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
110203042 (AKT1)
05142 Chagas disease
110203042 (AKT1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110203042 (AKT1)
01524 Platinum drug resistance
110203042 (AKT1)
01522 Endocrine resistance
110203042 (AKT1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcw01001
]
110203042 (AKT1)
Enzymes [BR:
pcw01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
110203042 (AKT1)
Protein kinases [BR:
pcw01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
110203042 (AKT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Pkinase_C
Kinase-like
PH_11
Seadorna_VP7
Pkinase_fungal
APH
Motif
Other DBs
NCBI-GeneID:
110203042
NCBI-ProteinID:
XP_020835126
UniProt:
A0A6P5JUQ5
LinkDB
All DBs
Position
Unknown
AA seq
480 aa
AA seq
DB search
MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPQDVDQRESPLNNFSVAQC
QLMKTERPKPNTFIIRCLQWTTVIERTFHVETPEEREEWTKAIQMVADSLKKQEEEMMDF
RSGSPSDNSGAEEMEVSTTKPKHKVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
ILMEEIRFPRTLSPDAKSLLSGLLKKDPKQRLGGGSDDAKEIMQHKFFAGIVWQDVYEKK
LVPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDNMECVDNERRPHFPQFSYSASGTA
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
atgaacgacgttgcgattgttaaggagggctggctgcataagcgaggagaatacatcaaa
acatggcggccacgctacttcttgctgaagagtgatgggagcttcattggctacaaggag
cggccacaggacgtggaccagcgggagtcacccctcaacaacttctcagttgcacaatgc
cagctgatgaagacagagcgacccaaacccaatacattcatcatccgctgcctgcagtgg
accacggtaattgagagaacgtttcacgtggagacccccgaggagcgggaagaatggacc
aaagccatacagatggtggctgacagcctgaaaaagcaagaggaagaaatgatggacttc
cggtcaggttcaccgagtgacaattccggggccgaggagatggaggtgtctacgacaaag
cccaaacacaaagtgacaatgaatgaattcgaatacctgaagctgctgggcaaaggcaca
tttgggaaggtgatcctggtgaaggagaaggcgaccgggagatactatgccatgaagatc
ctcaagaaggaagtgattgtggccaaggatgaggtggcacatacgcttacagagaaccga
gtcttgcagaactcaaggcacccgttcctgacagcactgaagtactcattccagacgcat
gaccgcctatgctttgtgatggagtatgccaatggaggagagctgtttttccatctctcc
cgagagcgggtattctccgaagaccgagccagattctacggggcagagattgtgtctgcg
ctggactacttgcattctgagaagaatgtagtgtacagggacctcaagttggaaaaccta
atgctggacaaagatggtcacatcaaaatcaccgacttcggtctgtgcaaggaggggatc
aaagatggtgctacaatgaagaccttctgtgggactccagaatatctggcccctgaggtg
ctagaagacaatgactatggccgggcagtggactggtggggcctaggagtggtgatgtat
gagatgatgtgtggccggctgcccttctacaaccaggaccatgagaagctgtttgagctg
atccttatggaggagattcgattcccccgaacgctctccccggatgccaagtctcttctg
tcggggttgctaaaaaaggaccccaagcagaggttaggtgggggatcagacgatgcaaaa
gagattatgcagcacaagttttttgctggcattgtatggcaagatgtctatgaaaaaaag
ctggtgcctccttttaagccgcaagtgacatctgagacagacaccaggtattttgatgag
gagtttacagcccagatgatcacaatcacccctcctgaccaagatgacaacatggagtgt
gtggacaatgagagacggccccactttcctcagttctcatactctgctagtgggacagcg
tga
Phascolarctos cinereus (koala): 110205475
Help
Entry
110205475 CDS
T05867
Gene name
AKT3
Definition
(RefSeq) RAC-gamma serine/threonine-protein kinase isoform X1
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw01521
EGFR tyrosine kinase inhibitor resistance
pcw01522
Endocrine resistance
pcw01524
Platinum drug resistance
pcw04010
MAPK signaling pathway
pcw04012
ErbB signaling pathway
pcw04014
Ras signaling pathway
pcw04015
Rap1 signaling pathway
pcw04022
cGMP-PKG signaling pathway
pcw04024
cAMP signaling pathway
pcw04062
Chemokine signaling pathway
pcw04066
HIF-1 signaling pathway
pcw04068
FoxO signaling pathway
pcw04071
Sphingolipid signaling pathway
pcw04072
Phospholipase D signaling pathway
pcw04140
Autophagy - animal
pcw04150
mTOR signaling pathway
pcw04151
PI3K-Akt signaling pathway
pcw04152
AMPK signaling pathway
pcw04210
Apoptosis
pcw04211
Longevity regulating pathway
pcw04213
Longevity regulating pathway - multiple species
pcw04218
Cellular senescence
pcw04261
Adrenergic signaling in cardiomyocytes
pcw04370
VEGF signaling pathway
pcw04371
Apelin signaling pathway
pcw04380
Osteoclast differentiation
pcw04510
Focal adhesion
pcw04550
Signaling pathways regulating pluripotency of stem cells
pcw04611
Platelet activation
pcw04613
Neutrophil extracellular trap formation
pcw04620
Toll-like receptor signaling pathway
pcw04625
C-type lectin receptor signaling pathway
pcw04630
JAK-STAT signaling pathway
pcw04660
T cell receptor signaling pathway
pcw04662
B cell receptor signaling pathway
pcw04664
Fc epsilon RI signaling pathway
pcw04666
Fc gamma R-mediated phagocytosis
pcw04668
TNF signaling pathway
pcw04722
Neurotrophin signaling pathway
pcw04725
Cholinergic synapse
pcw04728
Dopaminergic synapse
pcw04910
Insulin signaling pathway
pcw04914
Progesterone-mediated oocyte maturation
pcw04915
Estrogen signaling pathway
pcw04917
Prolactin signaling pathway
pcw04919
Thyroid hormone signaling pathway
pcw04920
Adipocytokine signaling pathway
pcw04922
Glucagon signaling pathway
pcw04923
Regulation of lipolysis in adipocytes
pcw04926
Relaxin signaling pathway
pcw04929
GnRH secretion
pcw04931
Insulin resistance
pcw04932
Non-alcoholic fatty liver disease
pcw04933
AGE-RAGE signaling pathway in diabetic complications
pcw04935
Growth hormone synthesis, secretion and action
pcw04973
Carbohydrate digestion and absorption
pcw05010
Alzheimer disease
pcw05017
Spinocerebellar ataxia
pcw05132
Salmonella infection
pcw05135
Yersinia infection
pcw05142
Chagas disease
pcw05145
Toxoplasmosis
pcw05152
Tuberculosis
pcw05160
Hepatitis C
pcw05161
Hepatitis B
pcw05162
Measles
pcw05163
Human cytomegalovirus infection
pcw05164
Influenza A
pcw05165
Human papillomavirus infection
pcw05166
Human T-cell leukemia virus 1 infection
pcw05167
Kaposi sarcoma-associated herpesvirus infection
pcw05168
Herpes simplex virus 1 infection
pcw05169
Epstein-Barr virus infection
pcw05170
Human immunodeficiency virus 1 infection
pcw05200
Pathways in cancer
pcw05205
Proteoglycans in cancer
pcw05210
Colorectal cancer
pcw05211
Renal cell carcinoma
pcw05212
Pancreatic cancer
pcw05213
Endometrial cancer
pcw05214
Glioma
pcw05215
Prostate cancer
pcw05218
Melanoma
pcw05220
Chronic myeloid leukemia
pcw05221
Acute myeloid leukemia
pcw05222
Small cell lung cancer
pcw05223
Non-small cell lung cancer
pcw05224
Breast cancer
pcw05225
Hepatocellular carcinoma
pcw05226
Gastric cancer
pcw05230
Central carbon metabolism in cancer
pcw05231
Choline metabolism in cancer
pcw05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
pcw05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110205475 (AKT3)
04012 ErbB signaling pathway
110205475 (AKT3)
04014 Ras signaling pathway
110205475 (AKT3)
04015 Rap1 signaling pathway
110205475 (AKT3)
04370 VEGF signaling pathway
110205475 (AKT3)
04371 Apelin signaling pathway
110205475 (AKT3)
04630 JAK-STAT signaling pathway
110205475 (AKT3)
04668 TNF signaling pathway
110205475 (AKT3)
04066 HIF-1 signaling pathway
110205475 (AKT3)
04068 FoxO signaling pathway
110205475 (AKT3)
04072 Phospholipase D signaling pathway
110205475 (AKT3)
04071 Sphingolipid signaling pathway
110205475 (AKT3)
04024 cAMP signaling pathway
110205475 (AKT3)
04022 cGMP-PKG signaling pathway
110205475 (AKT3)
04151 PI3K-Akt signaling pathway
110205475 (AKT3)
04152 AMPK signaling pathway
110205475 (AKT3)
04150 mTOR signaling pathway
110205475 (AKT3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
110205475 (AKT3)
09143 Cell growth and death
04210 Apoptosis
110205475 (AKT3)
04218 Cellular senescence
110205475 (AKT3)
09144 Cellular community - eukaryotes
04510 Focal adhesion
110205475 (AKT3)
04550 Signaling pathways regulating pluripotency of stem cells
110205475 (AKT3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
110205475 (AKT3)
04613 Neutrophil extracellular trap formation
110205475 (AKT3)
04620 Toll-like receptor signaling pathway
110205475 (AKT3)
04625 C-type lectin receptor signaling pathway
110205475 (AKT3)
04660 T cell receptor signaling pathway
110205475 (AKT3)
04662 B cell receptor signaling pathway
110205475 (AKT3)
04664 Fc epsilon RI signaling pathway
110205475 (AKT3)
04666 Fc gamma R-mediated phagocytosis
110205475 (AKT3)
04062 Chemokine signaling pathway
110205475 (AKT3)
09152 Endocrine system
04910 Insulin signaling pathway
110205475 (AKT3)
04922 Glucagon signaling pathway
110205475 (AKT3)
04923 Regulation of lipolysis in adipocytes
110205475 (AKT3)
04920 Adipocytokine signaling pathway
110205475 (AKT3)
04929 GnRH secretion
110205475 (AKT3)
04915 Estrogen signaling pathway
110205475 (AKT3)
04914 Progesterone-mediated oocyte maturation
110205475 (AKT3)
04917 Prolactin signaling pathway
110205475 (AKT3)
04926 Relaxin signaling pathway
110205475 (AKT3)
04935 Growth hormone synthesis, secretion and action
110205475 (AKT3)
04919 Thyroid hormone signaling pathway
110205475 (AKT3)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
110205475 (AKT3)
09154 Digestive system
04973 Carbohydrate digestion and absorption
110205475 (AKT3)
09156 Nervous system
04725 Cholinergic synapse
110205475 (AKT3)
04728 Dopaminergic synapse
110205475 (AKT3)
04722 Neurotrophin signaling pathway
110205475 (AKT3)
09158 Development and regeneration
04380 Osteoclast differentiation
110205475 (AKT3)
09149 Aging
04211 Longevity regulating pathway
110205475 (AKT3)
04213 Longevity regulating pathway - multiple species
110205475 (AKT3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110205475 (AKT3)
05205 Proteoglycans in cancer
110205475 (AKT3)
05230 Central carbon metabolism in cancer
110205475 (AKT3)
05231 Choline metabolism in cancer
110205475 (AKT3)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
110205475 (AKT3)
09162 Cancer: specific types
05210 Colorectal cancer
110205475 (AKT3)
05212 Pancreatic cancer
110205475 (AKT3)
05225 Hepatocellular carcinoma
110205475 (AKT3)
05226 Gastric cancer
110205475 (AKT3)
05214 Glioma
110205475 (AKT3)
05221 Acute myeloid leukemia
110205475 (AKT3)
05220 Chronic myeloid leukemia
110205475 (AKT3)
05218 Melanoma
110205475 (AKT3)
05211 Renal cell carcinoma
110205475 (AKT3)
05215 Prostate cancer
110205475 (AKT3)
05213 Endometrial cancer
110205475 (AKT3)
05224 Breast cancer
110205475 (AKT3)
05222 Small cell lung cancer
110205475 (AKT3)
05223 Non-small cell lung cancer
110205475 (AKT3)
09164 Neurodegenerative disease
05010 Alzheimer disease
110205475 (AKT3)
05017 Spinocerebellar ataxia
110205475 (AKT3)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
110205475 (AKT3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
110205475 (AKT3)
04931 Insulin resistance
110205475 (AKT3)
04933 AGE-RAGE signaling pathway in diabetic complications
110205475 (AKT3)
09171 Infectious disease: bacterial
05132 Salmonella infection
110205475 (AKT3)
05135 Yersinia infection
110205475 (AKT3)
05152 Tuberculosis
110205475 (AKT3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
110205475 (AKT3)
05170 Human immunodeficiency virus 1 infection
110205475 (AKT3)
05161 Hepatitis B
110205475 (AKT3)
05160 Hepatitis C
110205475 (AKT3)
05164 Influenza A
110205475 (AKT3)
05162 Measles
110205475 (AKT3)
05168 Herpes simplex virus 1 infection
110205475 (AKT3)
05163 Human cytomegalovirus infection
110205475 (AKT3)
05167 Kaposi sarcoma-associated herpesvirus infection
110205475 (AKT3)
05169 Epstein-Barr virus infection
110205475 (AKT3)
05165 Human papillomavirus infection
110205475 (AKT3)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
110205475 (AKT3)
05142 Chagas disease
110205475 (AKT3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110205475 (AKT3)
01524 Platinum drug resistance
110205475 (AKT3)
01522 Endocrine resistance
110205475 (AKT3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcw01001
]
110205475 (AKT3)
Enzymes [BR:
pcw01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
110205475 (AKT3)
Protein kinases [BR:
pcw01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
110205475 (AKT3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_C
Kinase-like
PH
FTA2
Motif
Other DBs
NCBI-GeneID:
110205475
NCBI-ProteinID:
XP_020837737
UniProt:
A0A6P5JU20
LinkDB
All DBs
Position
Unknown
AA seq
536 aa
AA seq
DB search
MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKSE
TSPNNTTFWSLKSFLGMHCLNHSRGKEAYQLRRKPSYFSIVYRTLGGECQLMKTERPKPN
TFIIRCLQWTTVIERTFHVDTPEERSLAFFFLEEWTEAIQAVADRLQRQEEERMNCSPTS
QIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEV
IIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVF
SEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATM
KTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDI
KFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFVGVNWQDVYDKKLVPPFK
PQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
NT seq
1611 nt
NT seq
+upstream
nt +downstream
nt
atgagcgatgttaccattgtgaaagaaggttgggttcagaagaggggagaatatataaaa
aactggaggccaagatacttccttttgaagacagatggctcattcataggatataaggag
aaacctcaagatgtggatttaccttatccccttaacaacttttcagtggcaaaaagtgaa
acatctcccaacaatactaccttttggtcactgaagtcttttctggggatgcattgtctg
aaccattccagaggcaaagaagcctaccagttgaggaggaaaccaagctatttctccatt
gtatacagaactcttggaggggaatgccaactcatgaaaacagaacgaccaaagccaaat
acatttattatcagatgcctccagtggaccactgttatagaacgaacatttcatgtggat
actccagaggaaaggtcacttgcttttttttttttggaagaatggacagaagctatccag
gctgtagcagacagacttcagaggcaagaagaagagagaatgaactgtagtccgacttca
caaattgataatataggagaggaggaaatggatgcttctacaactcatcataaaagaaag
acaatgaatgactttgactatttgaaactgttgggtaaaggcacttttggaaaagtgatt
ttggttcgagagaaggcaagtggaaaatattatgctatgaagattttgaagaaagaagta
attattgcaaaggatgaagtggcacatactctaacagaaagcagagtattaaaaaacact
aggcacccctttttaacttctttgaaatattccttccagacaaaagatcgtttgtgtttt
gtgatggagtatgttaatggaggagagctgtttttccatttgtcgagagagcgggtgttc
tctgaggaccgcacacgcttctatggtgcagaaattgtctcagctttggactatctacat
tctggaaagattgtgtaccgtgatctcaagttggaaaatttgatgttggataaagatggc
cacataaaaattacagattttggactttgcaaagaagggattacagatgcagctacgatg
aagacattttgtggtacacctgagtaccttgcacctgaggtattagaagataatgactat
ggccgtgcagtagactggtggggcctgggggttgtcatgtatgaaatgatgtgtgggaga
ttaccattctacaaccaggatcatgagaaactttttgagctaatattaatggaggacatt
aaatttcctcgaactctttcttctgatgcaaaatccttactttcaggactcttaataaaa
gatccaaataaacgccttggcggaggtccagatgatgcaaaagaaattatgaggcatagt
ttctttgttggagtaaactggcaagatgtatatgataaaaagctggtacctccttttaaa
cctcaagtaacgtctgagacagacaccagatattttgatgaagaatttacagctcagaca
attacaataacaccgcctgaaaaatatgatgaggatggtatggactgcatggacaatgag
agacggccacatttcccacagttttcctactctgcaagtggacgagaataa
DBGET
integrated database retrieval system
